Rab4 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	Rab4
Entrez Gene ID	36992
Full Name	CG4921 gene product from transcript CG4921-RA
Synonyms	CG 4921,CG4921,DRAB4,DmRab4,Dmel\CG4921,Q7KY04,RAB4c,rab4
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 2R Map Location: 54C9-54C10

mRNA and Protein(s)

mRNA	Protein	Name
NM_166240.3	NP_725696.1	Rab4, isoform A
NM_079053.4	NP_523777.1	Rab4, isoform B

Pathways from BioSystems

Homologies

Bos taurus (cattle)	RAB4B	NP_001121979.1
Danio rerio (zebrafish)	rab4b	NP_001004002.1
Xenopus tropicalis (tropical clawed frog)	rab4b	NP_001016987.1
Homo sapiens (human)	RAB4B	NP_057238.3
Drosophila melanogaster (fruit fly)	Rab4	NP_523777.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004204	XP_313105.2
Mus musculus (house mouse)	Rab4b	NP_083667.1
Canis lupus familiaris (dog)	RAB4B	NP_001003275.1
Rattus norvegicus (Norway rat)	Rab4b	NP_059051.1

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Rab4-dependent vesicular traffic toward the synapse plays a vital role in maintaining synaptic balance in this neuronal network.
Title: Anterograde Transport of Rab4-Associated Vesicles Regulates Synapse Organization in Drosophila.

Re-internalized Hedgehog is then regulated in a Rab5- and Rab4-dependent manner to ensure its long-range activity
Title: Endocytosis of Hedgehog through dispatched regulates long-range signaling.

The following Rab4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rab4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OFa13065	NM_166240.3 Latest version!	Drosophila melanogaster Rab4, transcript variant A (Rab4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00
OFa13065	NM_079053.4 Latest version!	Drosophila melanogaster Rab4, transcript variant B (Rab4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Rab4 ( NM_166240.3 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_725696.1 Drosophila melanogaster Rab4, transcript variant A (Rab4), mRNA.

Price & Availability↑

CloneID	OFa13065
Clone ID Related Accession (Same CDS sequence)	NM_166240.3 , NM_079053.4
Accession Version	NM_166240.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 642bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	Rab4, isoform A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033778). On Jul 15, 2014 this sequence version replaced NM_166240.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGTCGGAAA CATACGATTA CCTGTTCAAG TTCCTGATAA TTGGCAGTGC TGGCAGCGGT 
AAGAGTTGTC TGTTGCATCA CTTCATCGAG AGCAAGTTCA AAGACGACAG TTCGCACACC 
ATCGGAGTGG AGTTCGGCTC GCGGATTGTG AACGTGGGCG GCAAGTCGGT AAAGCTACAG 
ATATGGGACA CAGCCGGTCA GGAGAGATTC CGATCGGTGA CAAGATCGTA CTATCGCGGA 
GCAGCCGGAG CTCTCCTGGT CTACGATGCC ACTTCGCGGG ACTCTTTCAA TGCTTTGACA 
AACTGGCTGA ATGATGCTCG CACTCTGGCC AGCCCAAATA TTGTGATCCT TTTGGTGGGC 
AATAAAAAGG ACTTGGAGGA GGCGCGTGAT GTGACCTTTC TGGAAGCAAG CACCTTTGCC 
CAAGAGAACG AGCTTATCTT CCTGGAGACG AGCGCCAAGA CGGGGGAGAA TGTTGAAGAG 
GCCTTTCTCA AGTGCTCAAA GACCATACTG GCCAAAATTG AGACCGGAGA GCTGGATCCC 
GAGCGCATCG GCAGCGGTAT TCAGTACGGC GGAGCTGCTC TCCGTAACTT ACAGACACGA 
CAGCGCAGCA TCAATAAGCC GGATTGCACC TGTCGCGTTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_725696.1
CDS	238..879
Translation	MSETYDYLFKFLIIGSAGSGKSCLLHHFIESKFKDDSSHTIGVEFGSRIVNVGGKSVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDATSRDSFNALTNWLNDARTLASPNIVILLVGNKKDLEEARDVTFLEASTFAQENELIFLETSAKTGENVEEAFLKCSKTILAKIETGELDPERIGSGIQYGGAALRNLQTRQRSINKPDCTCRV

Target ORF information:

RefSeq Version	NM_166240.3
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster Rab4, transcript variant A (Rab4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_166240.3

ORF Insert Sequence:

ATGTCGGAAA CATACGATTA CCTGTTCAAG TTCCTGATAA TTGGCAGTGC TGGCAGCGGT 
AAGAGTTGTC TGTTGCATCA CTTCATCGAG AGCAAGTTCA AAGACGACAG TTCGCACACC 
ATCGGAGTGG AGTTCGGCTC GCGGATTGTG AACGTGGGCG GCAAGTCGGT AAAGCTACAG 
ATATGGGACA CAGCCGGTCA GGAGAGATTC CGATCGGTGA CAAGATCGTA CTATCGCGGA 
GCAGCCGGAG CTCTCCTGGT CTACGATGCC ACTTCGCGGG ACTCTTTCAA TGCTTTGACA 
AACTGGCTGA ATGATGCTCG CACTCTGGCC AGCCCAAATA TTGTGATCCT TTTGGTGGGC 
AATAAAAAGG ACTTGGAGGA GGCGCGTGAT GTGACCTTTC TGGAAGCAAG CACCTTTGCC 
CAAGAGAACG AGCTTATCTT CCTGGAGACG AGCGCCAAGA CGGGGGAGAA TGTTGAAGAG 
GCCTTTCTCA AGTGCTCAAA GACCATACTG GCCAAAATTG AGACCGGAGA GCTGGATCCC 
GAGCGCATCG GCAGCGGTAT TCAGTACGGC GGAGCTGCTC TCCGTAACTT ACAGACACGA 
CAGCGCAGCA TCAATAAGCC GGATTGCACC TGTCGCGTTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rab4 ( NM_079053.4 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_523777.1 Drosophila melanogaster Rab4, transcript variant B (Rab4), mRNA.

Price & Availability↑

CloneID	OFa13065
Clone ID Related Accession (Same CDS sequence)	NM_166240.3 , NM_079053.4
Accession Version	NM_079053.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 642bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	Rab4, isoform B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033778). On Jul 15, 2014 this sequence version replaced NM_079053.3. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGTCGGAAA CATACGATTA CCTGTTCAAG TTCCTGATAA TTGGCAGTGC TGGCAGCGGT 
AAGAGTTGTC TGTTGCATCA CTTCATCGAG AGCAAGTTCA AAGACGACAG TTCGCACACC 
ATCGGAGTGG AGTTCGGCTC GCGGATTGTG AACGTGGGCG GCAAGTCGGT AAAGCTACAG 
ATATGGGACA CAGCCGGTCA GGAGAGATTC CGATCGGTGA CAAGATCGTA CTATCGCGGA 
GCAGCCGGAG CTCTCCTGGT CTACGATGCC ACTTCGCGGG ACTCTTTCAA TGCTTTGACA 
AACTGGCTGA ATGATGCTCG CACTCTGGCC AGCCCAAATA TTGTGATCCT TTTGGTGGGC 
AATAAAAAGG ACTTGGAGGA GGCGCGTGAT GTGACCTTTC TGGAAGCAAG CACCTTTGCC 
CAAGAGAACG AGCTTATCTT CCTGGAGACG AGCGCCAAGA CGGGGGAGAA TGTTGAAGAG 
GCCTTTCTCA AGTGCTCAAA GACCATACTG GCCAAAATTG AGACCGGAGA GCTGGATCCC 
GAGCGCATCG GCAGCGGTAT TCAGTACGGC GGAGCTGCTC TCCGTAACTT ACAGACACGA 
CAGCGCAGCA TCAATAAGCC GGATTGCACC TGTCGCGTTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_523777.1
CDS	139..780
Translation	MSETYDYLFKFLIIGSAGSGKSCLLHHFIESKFKDDSSHTIGVEFGSRIVNVGGKSVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDATSRDSFNALTNWLNDARTLASPNIVILLVGNKKDLEEARDVTFLEASTFAQENELIFLETSAKTGENVEEAFLKCSKTILAKIETGELDPERIGSGIQYGGAALRNLQTRQRSINKPDCTCRV

Target ORF information:

RefSeq Version	NM_079053.4
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster Rab4, transcript variant B (Rab4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_079053.4

ORF Insert Sequence:

ATGTCGGAAA CATACGATTA CCTGTTCAAG TTCCTGATAA TTGGCAGTGC TGGCAGCGGT 
AAGAGTTGTC TGTTGCATCA CTTCATCGAG AGCAAGTTCA AAGACGACAG TTCGCACACC 
ATCGGAGTGG AGTTCGGCTC GCGGATTGTG AACGTGGGCG GCAAGTCGGT AAAGCTACAG 
ATATGGGACA CAGCCGGTCA GGAGAGATTC CGATCGGTGA CAAGATCGTA CTATCGCGGA 
GCAGCCGGAG CTCTCCTGGT CTACGATGCC ACTTCGCGGG ACTCTTTCAA TGCTTTGACA 
AACTGGCTGA ATGATGCTCG CACTCTGGCC AGCCCAAATA TTGTGATCCT TTTGGTGGGC 
AATAAAAAGG ACTTGGAGGA GGCGCGTGAT GTGACCTTTC TGGAAGCAAG CACCTTTGCC 
CAAGAGAACG AGCTTATCTT CCTGGAGACG AGCGCCAAGA CGGGGGAGAA TGTTGAAGAG 
GCCTTTCTCA AGTGCTCAAA GACCATACTG GCCAAAATTG AGACCGGAGA GCTGGATCCC 
GAGCGCATCG GCAGCGGTAT TCAGTACGGC GGAGCTGCTC TCCGTAACTT ACAGACACGA 
CAGCGCAGCA TCAATAAGCC GGATTGCACC TGTCGCGTTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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Rab4 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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