Gene Symbol | drosha |
Entrez Gene ID | 35747 |
Full Name | CG8730 gene product from transcript CG8730-RA |
Synonyms | CG8730,DROSHA,Dmel\CG8730,Drosha |
Gene Type | protein-coding |
Organism | Drosophila melanogaster(fruit fly) |
Genome |
ORF » Species Summary » Drosophila melanogaster » drosha cDNA ORF clone
Gene Symbol | drosha |
Entrez Gene ID | 35747 |
Full Name | CG8730 gene product from transcript CG8730-RA |
Synonyms | CG8730,DROSHA,Dmel\CG8730,Drosha |
Gene Type | protein-coding |
Organism | Drosophila melanogaster(fruit fly) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_058088.4 | NP_477436.1 | drosha |
Homo sapiens (human) | DROSHA | NP_037367.3 |
Mus musculus (house mouse) | Drosha | NP_001123621.1 |
Rattus norvegicus (Norway rat) | Drosha | NP_001101125.2 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP008087 | XP_555381.3 |
DROSHA | XP_002804372.1 | |
Caenorhabditis elegans (roundworm) | drsh-1 | NP_492599.1 |
Xenopus tropicalis (tropical clawed frog) | drosha | NP_001107152.1 |
Pan troglodytes (chimpanzee) | DROSHA | XP_001157472.2 |
Bos taurus (cattle) | DROSHA | XP_005221686.1 |
Canis lupus familiaris (dog) | DROSHA | XP_854135.2 |
Gallus gallus (chicken) | DROSHA | NP_001006379.1 |
Danio rerio (zebrafish) | rnasen | NP_001103942.1 |
Drosophila melanogaster (fruit fly) | drosha | NP_477436.1 |
Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Drosha and Pasha are required for coordinated development of somatic and germ cell precursors in the larval ovary. Loss of Drosha or Pasha function perturbs somatic precursor development, causing defects in formation of terminal filaments. Drosha-controlled miRNAs including miR-8, miR-14, miR-33, miR-184, miR-317 and let-7-C function in gonadogenesis.
Title: MicroRNA-dependent roles of Drosha and Pasha in the Drosophila larval ovary morphogenesis.
We propose that Drosha represents a unique and conserved arm of the cellular defenses used to combat virus infection.
Title: Drosha as an interferon-independent antiviral factor.
report clear phenotypic differences between drosha and pasha/dgcr8 null alleles in two postembryonic lineages in the Drosophila brain
Title: Drosha-independent DGCR8/Pasha pathway regulates neuronal morphogenesis.
Excess Drosha cleaves pasha/DGCR8 primary transcripts and leads to a reduction in pasha/DGCR8 mRNA levels and Pasha/DGCR8 synthesis.
Title: Genome-wide identification of targets of the drosha-pasha/DGCR8 complex.
A genome-wide analysis of mRNAs regulated by drosha was performed.
Title: Genome-wide analysis of mRNAs regulated by Drosha and Argonaute proteins in Drosophila melanogaster.
The following drosha gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the drosha cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OFa09219 | |
Clone ID Related Accession (Same CDS sequence) | NM_058088.4 | |
Accession Version | NM_058088.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3984bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-24 | |
Organism | Drosophila melanogaster(fruit fly) | |
Product | drosha | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033778). On Jul 15, 2014 this sequence version replaced NM_058088.3. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END## |
1 | ATGTACCAGC CGCCTTTGCC ACCGCCTCCA GTCCAGCCTG CTCCTCCGCC CCCGCCACCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_477436.1 |
CDS | 88..4071 |
Translation |
Target ORF information:
Target ORF information:
|
NM_058088.4 |
1 | ATGTACCAGC CGCCTTTGCC ACCGCCTCCA GTCCAGCCTG CTCCTCCGCC CCCGCCACCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data. |
Gene Model Annotations for Drosophila melanogaster: The Rule-Benders. |
Sequence finishing and mapping of Drosophila melanogaster heterochromatin. |
The Release 5.1 annotation of Drosophila melanogaster heterochromatin. |
Combined evidence annotation of transposable elements in genome sequences. |