sax cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	sax
Entrez Gene ID	35731
Full Name	saxophone
Synonyms	Bkr43E,Brk43E,CG1891,Dmel\CG1891,SAX,STK-B,Sa,Sax
General protein information	Preferred Names saxophone Names CG1891 gene product from transcript CG1891-RC CG1891-PA CG1891-PB CG1891-PC sax-PA sax-PB sax-PC
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 2R Map Location: 43E18-43E18\|2-57 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_078928.4	NP_523652.2	saxophone, isoform A
NM_001259264.2	NP_001246193.1	saxophone, isoform C
NM_165559.2	NP_724606.1	saxophone, isoform B

Pathways from BioSystems

Homologies

	ACVR1	XP_001089146.1
Gallus gallus (chicken)	ACVR1	NP_989891.1
Xenopus tropicalis (tropical clawed frog)	acvr1	NP_001017357.1
Bos taurus (cattle)	ACVR1	NP_788836.2
Danio rerio (zebrafish)	acvr1l	NP_571420.1
Drosophila melanogaster (fruit fly)	sax	NP_001246193.1
Homo sapiens (human)	ACVR1	NP_001096.1
Pan troglodytes (chimpanzee)	ACVR1	XP_001145316.1
Canis lupus familiaris (dog)	ACVR1	XP_005640253.1
Mus musculus (house mouse)	Acvr1	NP_001103674.1
Rattus norvegicus (Norway rat)	Acvr1	NP_077812.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP007729	XP_308147.4

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Heterodimers of SAX and TKV play an important role in extending the BMP activity gradient by facilitating DPP diffusion and assisting GBB signaling through functional complexes with type II receptors.
Title: The interaction between two TGF-beta type I receptors plays important roles in ligand binding, SMAD activation, and gradient formation.

Data show different functional requirements for the Sax receptor, and provide a mechanistic framework for future investigations into disease states that arise from defects in BMP/TGF-beta signaling.
Title: Functional analysis of saxophone, the Drosophila gene encoding the BMP type I receptor ortholog of human ALK1/ACVRL1 and ACVR1/ALK2.

Dad inhibited Saxophone and Thickveins but not Baboon.
Title: Specificity of the inhibitory effects of Dad on TGF-beta family type I receptors, Thickveins, Saxophone, and Baboon in Drosophila.

Smox acts downstream of Sax to prevent spermatogonial over-proliferation in Drosophila.
Title: TGFbeta receptor saxophone non-autonomously regulates germline proliferation in a Smox/dSmad2-dependent manner in Drosophila testis.

ALK1 and ALK2 facilitate Bmp signaling, but when alone, ALK1 and ALK2 fail to signal effectively and sequester Gbb
Title: Dual function of the Drosophila Alk1/Alk2 ortholog Saxophone shapes the Bmp activity gradient in the wing imaginal disc.

The following sax gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the sax cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OFa09197	NM_078928.4 Latest version!	Drosophila melanogaster saxophone (sax), transcript variant A, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00
OFa09198	NM_165559.2 Latest version!	Drosophila melanogaster saxophone (sax), transcript variant B, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00
OFa12762	NM_001259264.2 Latest version!	Drosophila melanogaster saxophone (sax), transcript variant C, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

sax ( NM_078928.4 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_523652.2 Drosophila melanogaster saxophone (sax), transcript variant A, mRNA.

Price & Availability↑

CloneID	OFa09197
Clone ID Related Accession (Same CDS sequence)	NM_078928.4
Accession Version	NM_078928.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1713bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	saxophone, isoform A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033778). On Jul 15, 2014 this sequence version replaced NM_078928.3. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGAGTCCA ATATATATTT AGTTTTTCTA TTGACGTTTC TGCTGTACAA TAATGCCAGA 
GCCGAAATCA GCGATCATCT GCGGGAGGAC ATACCGGACT TAGACATGGA GCTCTCCTCC 
GCCTCATCCG CCCATCTCAA TGGCAAGGAG CTACCGGCCG TGCCACAGAA CTCGGTGCAG 
ACGCATCCCA GATACAAATG CTACTCCTGC GAGCCGCCCT GTCGGGATCC CTATGAGTTT 
ACCCACACCT GCCAGAATGC GATTCAGTGC TGGAAGTCGC GCACACGCGA TGCCGATGGT 
CAGGTGCAGG AGTCACGCGG CTGCAGCACC TCGCCGGATC AACTGCCCAT GATCTGCAGC 
CAGAACTCCT TGAAGATCAA CGGGCCCAGT AAACGCAATA CGGGGAAGTT CGTGAATGTG 
GTCTGCTGTG CCGGTGATTA CTGCAATGAG GGAGACTTTC CGGAACTGCT GCCCTTCGAC 
AGCAATGATG TGACGGTGAT AACCGCGGAT ACCAGTAGCA TAAGCAAGAT GCTCGTCGCC 
GTTCTGGGTC CTTTTCTGGT CATCGCTCTG CTGGGCGCCG TGACCATCTT CTTCATTCGT 
CGTAGCCATC GCAAGCGTCT GGCTGCCTCG CGAACCAAAC AGGACCCGGA AGCGTATCTG 
GTCAATGATG AGCTGCTCCG CGCCACCAGC GCCGGGGACA GTACGCTGAG GGAGTATCTG 
CAGCACTCGG TGACCTCCGG CTCGGGCAGC GGATTGCCGC TGCTAGTGCA GCGTACGCTA 
GCCAAACAGG TCACCCTGAT CGAGTGCATT GGACGAGGCA AATACGGCGA GGTTTGGCGC 
GGTCACTGGC ATGGCGAAAG CATCGCCGTG AAGATATTCT TCAGTCGCGA CGAGGAGTCC 
TGGAAGCGGG AGACAGAGAT ATATAGCACC ATATTGCTAC GACATGAAAA TATTCTGGGA 
TTCATCGGCT CTGACATGAC GTCGCGGAAC TCGTGCACCC AACTTTGGCT GATGACGCAC 
TACTATCCAC TGGGCTCGCT CTTTGATCAC CTAAACCGTA ACGCCCTAAG CCACAACGAT 
ATGGTATGGA TTTGCCTGTC CATAGCTAAT GGGCTGGTAC ACTTGCACAC AGAGATATTC 
GGCAAGCAAG GCAAGCCAGC TATGGCCCAC CGCGATTTGA AGTCAAAGAA TATACTGGTC 
ACCTCGAACG GCTCCTGCGT GATAGCCGAT TTTGGACTGG CCGTTACCCA TTCGCACGTC 
ACAGGACAAC TGGACCTGGG CAACAACCCC AAAGTGGGCA CCAAGCGCTA CATGGCCCCA 
GAGGTTCTTG ATGAAAGCAT TGATTTAGAA TGCTTCGAAG CACTACGCCG GACAGATATT 
TACGCATTTG GACTTGTCCT CTGGGAGGTT TGTCGCCGCA CCATTTCTTG CGGCATAGCA 
GAGGAGTACA AGGTGCCCTT CTACGATGTG GTGCCAATGG ATCCCAGCTT CGAGGATATG 
CGCAAGGTGG TCTGCATCGA CAACTACAGG CCCTCCATTC CCAATCGCTG GAGCTCGGAT 
TCGTTAATGA CTGGCATGTC CAAGCTCATG AAGGAGTGCT GGCACCAAAA CCCCGACGTG 
CGCTTGCCAG CGCTGCGCAT CAAAAAGACT ATACATAAGC TGGCTTCCGC TGACGAGAAG 
ATACGCCTGG ACTTCGACGA GGTCTGCGTT TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_523652.2
CDS	55..1767
Translation	MESNIYLVFLLTFLLYNNARAEISDHLREDIPDLDMELSSASSAHLNGKELPAVPQNSVQTHPRYKCYSCEPPCRDPYEFTHTCQNAIQCWKSRTRDADGQVQESRGCSTSPDQLPMICSQNSLKINGPSKRNTGKFVNVVCCAGDYCNEGDFPELLPFDSNDVTVITADTSSISKMLVAVLGPFLVIALLGAVTIFFIRRSHRKRLAASRTKQDPEAYLVNDELLRATSAGDSTLREYLQHSVTSGSGSGLPLLVQRTLAKQVTLIECIGRGKYGEVWRGHWHGESIAVKIFFSRDEESWKRETEIYSTILLRHENILGFIGSDMTSRNSCTQLWLMTHYYPLGSLFDHLNRNALSHNDMVWICLSIANGLVHLHTEIFGKQGKPAMAHRDLKSKNILVTSNGSCVIADFGLAVTHSHVTGQLDLGNNPKVGTKRYMAPEVLDESIDLECFEALRRTDIYAFGLVLWEVCRRTISCGIAEEYKVPFYDVVPMDPSFEDMRKVVCIDNYRPSIPNRWSSDSLMTGMSKLMKECWHQNPDVRLPALRIKKTIHKLASADEKIRLDFDEVCV

Target ORF information:

RefSeq Version	NM_078928.4
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster saxophone (sax), transcript variant A, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_078928.4

ORF Insert Sequence:

ATGGAGTCCA ATATATATTT AGTTTTTCTA TTGACGTTTC TGCTGTACAA TAATGCCAGA 
GCCGAAATCA GCGATCATCT GCGGGAGGAC ATACCGGACT TAGACATGGA GCTCTCCTCC 
GCCTCATCCG CCCATCTCAA TGGCAAGGAG CTACCGGCCG TGCCACAGAA CTCGGTGCAG 
ACGCATCCCA GATACAAATG CTACTCCTGC GAGCCGCCCT GTCGGGATCC CTATGAGTTT 
ACCCACACCT GCCAGAATGC GATTCAGTGC TGGAAGTCGC GCACACGCGA TGCCGATGGT 
CAGGTGCAGG AGTCACGCGG CTGCAGCACC TCGCCGGATC AACTGCCCAT GATCTGCAGC 
CAGAACTCCT TGAAGATCAA CGGGCCCAGT AAACGCAATA CGGGGAAGTT CGTGAATGTG 
GTCTGCTGTG CCGGTGATTA CTGCAATGAG GGAGACTTTC CGGAACTGCT GCCCTTCGAC 
AGCAATGATG TGACGGTGAT AACCGCGGAT ACCAGTAGCA TAAGCAAGAT GCTCGTCGCC 
GTTCTGGGTC CTTTTCTGGT CATCGCTCTG CTGGGCGCCG TGACCATCTT CTTCATTCGT 
CGTAGCCATC GCAAGCGTCT GGCTGCCTCG CGAACCAAAC AGGACCCGGA AGCGTATCTG 
GTCAATGATG AGCTGCTCCG CGCCACCAGC GCCGGGGACA GTACGCTGAG GGAGTATCTG 
CAGCACTCGG TGACCTCCGG CTCGGGCAGC GGATTGCCGC TGCTAGTGCA GCGTACGCTA 
GCCAAACAGG TCACCCTGAT CGAGTGCATT GGACGAGGCA AATACGGCGA GGTTTGGCGC 
GGTCACTGGC ATGGCGAAAG CATCGCCGTG AAGATATTCT TCAGTCGCGA CGAGGAGTCC 
TGGAAGCGGG AGACAGAGAT ATATAGCACC ATATTGCTAC GACATGAAAA TATTCTGGGA 
TTCATCGGCT CTGACATGAC GTCGCGGAAC TCGTGCACCC AACTTTGGCT GATGACGCAC 
TACTATCCAC TGGGCTCGCT CTTTGATCAC CTAAACCGTA ACGCCCTAAG CCACAACGAT 
ATGGTATGGA TTTGCCTGTC CATAGCTAAT GGGCTGGTAC ACTTGCACAC AGAGATATTC 
GGCAAGCAAG GCAAGCCAGC TATGGCCCAC CGCGATTTGA AGTCAAAGAA TATACTGGTC 
ACCTCGAACG GCTCCTGCGT GATAGCCGAT TTTGGACTGG CCGTTACCCA TTCGCACGTC 
ACAGGACAAC TGGACCTGGG CAACAACCCC AAAGTGGGCA CCAAGCGCTA CATGGCCCCA 
GAGGTTCTTG ATGAAAGCAT TGATTTAGAA TGCTTCGAAG CACTACGCCG GACAGATATT 
TACGCATTTG GACTTGTCCT CTGGGAGGTT TGTCGCCGCA CCATTTCTTG CGGCATAGCA 
GAGGAGTACA AGGTGCCCTT CTACGATGTG GTGCCAATGG ATCCCAGCTT CGAGGATATG 
CGCAAGGTGG TCTGCATCGA CAACTACAGG CCCTCCATTC CCAATCGCTG GAGCTCGGAT 
TCGTTAATGA CTGGCATGTC CAAGCTCATG AAGGAGTGCT GGCACCAAAA CCCCGACGTG 
CGCTTGCCAG CGCTGCGCAT CAAAAAGACT ATACATAAGC TGGCTTCCGC TGACGAGAAG 
ATACGCCTGG ACTTCGACGA GGTCTGCGTT TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

sax ( NM_165559.2 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_724606.1 Drosophila melanogaster saxophone (sax), transcript variant B, mRNA.

Price & Availability↑

CloneID	OFa09198
Clone ID Related Accession (Same CDS sequence)	NM_165559.2
Accession Version	NM_165559.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1608bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	saxophone, isoform B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033778). On May 8, 2012 this sequence version replaced NM_165559.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGAGCTCT CCTCCGCCTC ATCCGCCCAT CTCAATGGCA AGGAGCTACC GGCCGTGCCA 
CAGAACTCGG TGCAGACGCA TCCCAGATAC AAATGCTACT CCTGCGAGCC GCCCTGTCGG 
GATCCCTATG AGTTTACCCA CACCTGCCAG AATGCGATTC AGTGCTGGAA GTCGCGCACA 
CGCGATGCCG ATGGTCAGGT GCAGGAGTCA CGCGGCTGCA GCACCTCGCC GGATCAACTG 
CCCATGATCT GCAGCCAGAA CTCCTTGAAG ATCAACGGGC CCAGTAAACG CAATACGGGG 
AAGTTCGTGA ATGTGGTCTG CTGTGCCGGT GATTACTGCA ATGAGGGAGA CTTTCCGGAA 
CTGCTGCCCT TCGACAGCAA TGATGTGACG GTGATAACCG CGGATACCAG TAGCATAAGC 
AAGATGCTCG TCGCCGTTCT GGGTCCTTTT CTGGTCATCG CTCTGCTGGG CGCCGTGACC 
ATCTTCTTCA TTCGTCGTAG CCATCGCAAG CGTCTGGCTG CCTCGCGAAC CAAACAGGAC 
CCGGAAGCGT ATCTGGTCAA TGATGAGCTG CTCCGCGCCA CCAGCGCCGG GGACAGTACG 
CTGAGGGAGT ATCTGCAGCA CTCGGTGACC TCCGGCTCGG GCAGCGGATT GCCGCTGCTA 
GTGCAGCGTA CGCTAGCCAA ACAGGTCACC CTGATCGAGT GCATTGGACG AGGCAAATAC 
GGCGAGGTTT GGCGCGGTCA CTGGCATGGC GAAAGCATCG CCGTGAAGAT ATTCTTCAGT 
CGCGACGAGG AGTCCTGGAA GCGGGAGACA GAGATATATA GCACCATATT GCTACGACAT 
GAAAATATTC TGGGATTCAT CGGCTCTGAC ATGACGTCGC GGAACTCGTG CACCCAACTT 
TGGCTGATGA CGCACTACTA TCCACTGGGC TCGCTCTTTG ATCACCTAAA CCGTAACGCC 
CTAAGCCACA ACGATATGGT ATGGATTTGC CTGTCCATAG CTAATGGGCT GGTACACTTG 
CACACAGAGA TATTCGGCAA GCAAGGCAAG CCAGCTATGG CCCACCGCGA TTTGAAGTCA 
AAGAATATAC TGGTCACCTC GAACGGCTCC TGCGTGATAG CCGATTTTGG ACTGGCCGTT 
ACCCATTCGC ACGTCACAGG ACAACTGGAC CTGGGCAACA ACCCCAAAGT GGGCACCAAG 
CGCTACATGG CCCCAGAGGT TCTTGATGAA AGCATTGATT TAGAATGCTT CGAAGCACTA 
CGCCGGACAG ATATTTACGC ATTTGGACTT GTCCTCTGGG AGGTTTGTCG CCGCACCATT 
TCTTGCGGCA TAGCAGAGGA GTACAAGGTG CCCTTCTACG ATGTGGTGCC AATGGATCCC 
AGCTTCGAGG ATATGCGCAA GGTGGTCTGC ATCGACAACT ACAGGCCCTC CATTCCCAAT 
CGCTGGAGCT CGGATTCGTT AATGACTGGC ATGTCCAAGC TCATGAAGGA GTGCTGGCAC 
CAAAACCCCG ACGTGCGCTT GCCAGCGCTG CGCATCAAAA AGACTATACA TAAGCTGGCT 
TCCGCTGACG AGAAGATACG CCTGGACTTC GACGAGGTCT GCGTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_724606.1
CDS	461..2068
Translation	MELSSASSAHLNGKELPAVPQNSVQTHPRYKCYSCEPPCRDPYEFTHTCQNAIQCWKSRTRDADGQVQESRGCSTSPDQLPMICSQNSLKINGPSKRNTGKFVNVVCCAGDYCNEGDFPELLPFDSNDVTVITADTSSISKMLVAVLGPFLVIALLGAVTIFFIRRSHRKRLAASRTKQDPEAYLVNDELLRATSAGDSTLREYLQHSVTSGSGSGLPLLVQRTLAKQVTLIECIGRGKYGEVWRGHWHGESIAVKIFFSRDEESWKRETEIYSTILLRHENILGFIGSDMTSRNSCTQLWLMTHYYPLGSLFDHLNRNALSHNDMVWICLSIANGLVHLHTEIFGKQGKPAMAHRDLKSKNILVTSNGSCVIADFGLAVTHSHVTGQLDLGNNPKVGTKRYMAPEVLDESIDLECFEALRRTDIYAFGLVLWEVCRRTISCGIAEEYKVPFYDVVPMDPSFEDMRKVVCIDNYRPSIPNRWSSDSLMTGMSKLMKECWHQNPDVRLPALRIKKTIHKLASADEKIRLDFDEVCV

Target ORF information:

RefSeq Version	NM_165559.2
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster saxophone (sax), transcript variant B, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_165559.2

ORF Insert Sequence:

ATGGAGCTCT CCTCCGCCTC ATCCGCCCAT CTCAATGGCA AGGAGCTACC GGCCGTGCCA 
CAGAACTCGG TGCAGACGCA TCCCAGATAC AAATGCTACT CCTGCGAGCC GCCCTGTCGG 
GATCCCTATG AGTTTACCCA CACCTGCCAG AATGCGATTC AGTGCTGGAA GTCGCGCACA 
CGCGATGCCG ATGGTCAGGT GCAGGAGTCA CGCGGCTGCA GCACCTCGCC GGATCAACTG 
CCCATGATCT GCAGCCAGAA CTCCTTGAAG ATCAACGGGC CCAGTAAACG CAATACGGGG 
AAGTTCGTGA ATGTGGTCTG CTGTGCCGGT GATTACTGCA ATGAGGGAGA CTTTCCGGAA 
CTGCTGCCCT TCGACAGCAA TGATGTGACG GTGATAACCG CGGATACCAG TAGCATAAGC 
AAGATGCTCG TCGCCGTTCT GGGTCCTTTT CTGGTCATCG CTCTGCTGGG CGCCGTGACC 
ATCTTCTTCA TTCGTCGTAG CCATCGCAAG CGTCTGGCTG CCTCGCGAAC CAAACAGGAC 
CCGGAAGCGT ATCTGGTCAA TGATGAGCTG CTCCGCGCCA CCAGCGCCGG GGACAGTACG 
CTGAGGGAGT ATCTGCAGCA CTCGGTGACC TCCGGCTCGG GCAGCGGATT GCCGCTGCTA 
GTGCAGCGTA CGCTAGCCAA ACAGGTCACC CTGATCGAGT GCATTGGACG AGGCAAATAC 
GGCGAGGTTT GGCGCGGTCA CTGGCATGGC GAAAGCATCG CCGTGAAGAT ATTCTTCAGT 
CGCGACGAGG AGTCCTGGAA GCGGGAGACA GAGATATATA GCACCATATT GCTACGACAT 
GAAAATATTC TGGGATTCAT CGGCTCTGAC ATGACGTCGC GGAACTCGTG CACCCAACTT 
TGGCTGATGA CGCACTACTA TCCACTGGGC TCGCTCTTTG ATCACCTAAA CCGTAACGCC 
CTAAGCCACA ACGATATGGT ATGGATTTGC CTGTCCATAG CTAATGGGCT GGTACACTTG 
CACACAGAGA TATTCGGCAA GCAAGGCAAG CCAGCTATGG CCCACCGCGA TTTGAAGTCA 
AAGAATATAC TGGTCACCTC GAACGGCTCC TGCGTGATAG CCGATTTTGG ACTGGCCGTT 
ACCCATTCGC ACGTCACAGG ACAACTGGAC CTGGGCAACA ACCCCAAAGT GGGCACCAAG 
CGCTACATGG CCCCAGAGGT TCTTGATGAA AGCATTGATT TAGAATGCTT CGAAGCACTA 
CGCCGGACAG ATATTTACGC ATTTGGACTT GTCCTCTGGG AGGTTTGTCG CCGCACCATT 
TCTTGCGGCA TAGCAGAGGA GTACAAGGTG CCCTTCTACG ATGTGGTGCC AATGGATCCC 
AGCTTCGAGG ATATGCGCAA GGTGGTCTGC ATCGACAACT ACAGGCCCTC CATTCCCAAT 
CGCTGGAGCT CGGATTCGTT AATGACTGGC ATGTCCAAGC TCATGAAGGA GTGCTGGCAC 
CAAAACCCCG ACGTGCGCTT GCCAGCGCTG CGCATCAAAA AGACTATACA TAAGCTGGCT 
TCCGCTGACG AGAAGATACG CCTGGACTTC GACGAGGTCT GCGTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

sax ( NM_001259264.2 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_001246193.1 Drosophila melanogaster saxophone (sax), transcript variant C, mRNA.

Price & Availability↑

CloneID	OFa12762
Clone ID Related Accession (Same CDS sequence)	NM_001259264.2
Accession Version	NM_001259264.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1749bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	saxophone, isoform C
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033778). On Jul 15, 2014 this sequence version replaced NM_001259264.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGAGTCCA ATATATATTT AGTTTTTCTA TTGACGTTTC TGCTGTACAA TAATGCCAGA 
GCCGAAATCA GCGATCATCT GCGGGAGGAC ATACCGGACT TAGACATGGA GCTCTCCTCC 
GCCTCATCCG CCCATCTCAA TGGCAAGGAG CTACCGGCCG TGCCACAGAA CTCGGTGCAG 
ACGCATCCCA GGAGACACAT TAAGAGTAAG CGCCGCATGA AGAGAAGATA CAAATGCTAC 
TCCTGCGAGC CGCCCTGTCG GGATCCCTAT GAGTTTACCC ACACCTGCCA GAATGCGATT 
CAGTGCTGGA AGTCGCGCAC ACGCGATGCC GATGGTCAGG TGCAGGAGTC ACGCGGCTGC 
AGCACCTCGC CGGATCAACT GCCCATGATC TGCAGCCAGA ACTCCTTGAA GATCAACGGG 
CCCAGTAAAC GCAATACGGG GAAGTTCGTG AATGTGGTCT GCTGTGCCGG TGATTACTGC 
AATGAGGGAG ACTTTCCGGA ACTGCTGCCC TTCGACAGCA ATGATGTGAC GGTGATAACC 
GCGGATACCA GTAGCATAAG CAAGATGCTC GTCGCCGTTC TGGGTCCTTT TCTGGTCATC 
GCTCTGCTGG GCGCCGTGAC CATCTTCTTC ATTCGTCGTA GCCATCGCAA GCGTCTGGCT 
GCCTCGCGAA CCAAACAGGA CCCGGAAGCG TATCTGGTCA ATGATGAGCT GCTCCGCGCC 
ACCAGCGCCG GGGACAGTAC GCTGAGGGAG TATCTGCAGC ACTCGGTGAC CTCCGGCTCG 
GGCAGCGGAT TGCCGCTGCT AGTGCAGCGT ACGCTAGCCA AACAGGTCAC CCTGATCGAG 
TGCATTGGAC GAGGCAAATA CGGCGAGGTT TGGCGCGGTC ACTGGCATGG CGAAAGCATC 
GCCGTGAAGA TATTCTTCAG TCGCGACGAG GAGTCCTGGA AGCGGGAGAC AGAGATATAT 
AGCACCATAT TGCTACGACA TGAAAATATT CTGGGATTCA TCGGCTCTGA CATGACGTCG 
CGGAACTCGT GCACCCAACT TTGGCTGATG ACGCACTACT ATCCACTGGG CTCGCTCTTT 
GATCACCTAA ACCGTAACGC CCTAAGCCAC AACGATATGG TATGGATTTG CCTGTCCATA 
GCTAATGGGC TGGTACACTT GCACACAGAG ATATTCGGCA AGCAAGGCAA GCCAGCTATG 
GCCCACCGCG ATTTGAAGTC AAAGAATATA CTGGTCACCT CGAACGGCTC CTGCGTGATA 
GCCGATTTTG GACTGGCCGT TACCCATTCG CACGTCACAG GACAACTGGA CCTGGGCAAC 
AACCCCAAAG TGGGCACCAA GCGCTACATG GCCCCAGAGG TTCTTGATGA AAGCATTGAT 
TTAGAATGCT TCGAAGCACT ACGCCGGACA GATATTTACG CATTTGGACT TGTCCTCTGG 
GAGGTTTGTC GCCGCACCAT TTCTTGCGGC ATAGCAGAGG AGTACAAGGT GCCCTTCTAC 
GATGTGGTGC CAATGGATCC CAGCTTCGAG GATATGCGCA AGGTGGTCTG CATCGACAAC 
TACAGGCCCT CCATTCCCAA TCGCTGGAGC TCGGATTCGT TAATGACTGG CATGTCCAAG 
CTCATGAAGG AGTGCTGGCA CCAAAACCCC GACGTGCGCT TGCCAGCGCT GCGCATCAAA 
AAGACTATAC ATAAGCTGGC TTCCGCTGAC GAGAAGATAC GCCTGGACTT CGACGAGGTC 
TGCGTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001246193.1
CDS	55..1803
Translation	MESNIYLVFLLTFLLYNNARAEISDHLREDIPDLDMELSSASSAHLNGKELPAVPQNSVQTHPRRHIKSKRRMKRRYKCYSCEPPCRDPYEFTHTCQNAIQCWKSRTRDADGQVQESRGCSTSPDQLPMICSQNSLKINGPSKRNTGKFVNVVCCAGDYCNEGDFPELLPFDSNDVTVITADTSSISKMLVAVLGPFLVIALLGAVTIFFIRRSHRKRLAASRTKQDPEAYLVNDELLRATSAGDSTLREYLQHSVTSGSGSGLPLLVQRTLAKQVTLIECIGRGKYGEVWRGHWHGESIAVKIFFSRDEESWKRETEIYSTILLRHENILGFIGSDMTSRNSCTQLWLMTHYYPLGSLFDHLNRNALSHNDMVWICLSIANGLVHLHTEIFGKQGKPAMAHRDLKSKNILVTSNGSCVIADFGLAVTHSHVTGQLDLGNNPKVGTKRYMAPEVLDESIDLECFEALRRTDIYAFGLVLWEVCRRTISCGIAEEYKVPFYDVVPMDPSFEDMRKVVCIDNYRPSIPNRWSSDSLMTGMSKLMKECWHQNPDVRLPALRIKKTIHKLASADEKIRLDFDEVCV

Target ORF information:

RefSeq Version	NM_001259264.2
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster saxophone (sax), transcript variant C, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001259264.2

ORF Insert Sequence:

ATGGAGTCCA ATATATATTT AGTTTTTCTA TTGACGTTTC TGCTGTACAA TAATGCCAGA 
GCCGAAATCA GCGATCATCT GCGGGAGGAC ATACCGGACT TAGACATGGA GCTCTCCTCC 
GCCTCATCCG CCCATCTCAA TGGCAAGGAG CTACCGGCCG TGCCACAGAA CTCGGTGCAG 
ACGCATCCCA GGAGACACAT TAAGAGTAAG CGCCGCATGA AGAGAAGATA CAAATGCTAC 
TCCTGCGAGC CGCCCTGTCG GGATCCCTAT GAGTTTACCC ACACCTGCCA GAATGCGATT 
CAGTGCTGGA AGTCGCGCAC ACGCGATGCC GATGGTCAGG TGCAGGAGTC ACGCGGCTGC 
AGCACCTCGC CGGATCAACT GCCCATGATC TGCAGCCAGA ACTCCTTGAA GATCAACGGG 
CCCAGTAAAC GCAATACGGG GAAGTTCGTG AATGTGGTCT GCTGTGCCGG TGATTACTGC 
AATGAGGGAG ACTTTCCGGA ACTGCTGCCC TTCGACAGCA ATGATGTGAC GGTGATAACC 
GCGGATACCA GTAGCATAAG CAAGATGCTC GTCGCCGTTC TGGGTCCTTT TCTGGTCATC 
GCTCTGCTGG GCGCCGTGAC CATCTTCTTC ATTCGTCGTA GCCATCGCAA GCGTCTGGCT 
GCCTCGCGAA CCAAACAGGA CCCGGAAGCG TATCTGGTCA ATGATGAGCT GCTCCGCGCC 
ACCAGCGCCG GGGACAGTAC GCTGAGGGAG TATCTGCAGC ACTCGGTGAC CTCCGGCTCG 
GGCAGCGGAT TGCCGCTGCT AGTGCAGCGT ACGCTAGCCA AACAGGTCAC CCTGATCGAG 
TGCATTGGAC GAGGCAAATA CGGCGAGGTT TGGCGCGGTC ACTGGCATGG CGAAAGCATC 
GCCGTGAAGA TATTCTTCAG TCGCGACGAG GAGTCCTGGA AGCGGGAGAC AGAGATATAT 
AGCACCATAT TGCTACGACA TGAAAATATT CTGGGATTCA TCGGCTCTGA CATGACGTCG 
CGGAACTCGT GCACCCAACT TTGGCTGATG ACGCACTACT ATCCACTGGG CTCGCTCTTT 
GATCACCTAA ACCGTAACGC CCTAAGCCAC AACGATATGG TATGGATTTG CCTGTCCATA 
GCTAATGGGC TGGTACACTT GCACACAGAG ATATTCGGCA AGCAAGGCAA GCCAGCTATG 
GCCCACCGCG ATTTGAAGTC AAAGAATATA CTGGTCACCT CGAACGGCTC CTGCGTGATA 
GCCGATTTTG GACTGGCCGT TACCCATTCG CACGTCACAG GACAACTGGA CCTGGGCAAC 
AACCCCAAAG TGGGCACCAA GCGCTACATG GCCCCAGAGG TTCTTGATGA AAGCATTGAT 
TTAGAATGCT TCGAAGCACT ACGCCGGACA GATATTTACG CATTTGGACT TGTCCTCTGG 
GAGGTTTGTC GCCGCACCAT TTCTTGCGGC ATAGCAGAGG AGTACAAGGT GCCCTTCTAC 
GATGTGGTGC CAATGGATCC CAGCTTCGAG GATATGCGCA AGGTGGTCTG CATCGACAAC 
TACAGGCCCT CCATTCCCAA TCGCTGGAGC TCGGATTCGT TAATGACTGG CATGTCCAAG 
CTCATGAAGG AGTGCTGGCA CCAAAACCCC GACGTGCGCT TGCCAGCGCT GCGCATCAAA 
AAGACTATAC ATAAGCTGGC TTCCGCTGAC GAGAAGATAC GCCTGGACTT CGACGAGGTC 
TGCGTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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sax cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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