Tdc1 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	Tdc1
Entrez Gene ID	35573
Full Name	Tyrosine decarboxylase 1
Synonyms	CG30445,CG3686,Dmel\CG30445,dTdc1,tdc,tdc1
General protein information	Preferred Names Tyrosine decarboxylase 1 Names CG30445 gene product from transcript CG30445-RA CG30445-PA Tdc1-PA tdc1 tyramine decarboxylase 1 tyrosine decarboxylase tyrosine decarboxylase 1
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 2R Map Location: 42C4-42C4

mRNA and Protein(s)

mRNA	Protein	Name
NM_136382.3	NP_610226.2	tyrosine decarboxylase 1

Pathways from BioSystems

Homologies

Drosophila melanogaster (fruit fly)	Tdc1	NP_610226.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP007302	XP_308521.3

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Synthesis of tyramine by Tdc1 in the principal cells of the Malpighian tubule is required for physiological responses to tyrosine.
Title: Isoform- and cell-specific function of tyrosine decarboxylase in the Drosophila Malpighian tubule.

dTdc1 and dTdc2 are functional but noncomplementing Drosophila tyrosine decarboxylase genes: dTdc1 is expressed nonneurally, whereas dTdc2 is expressed neurally
Title: Two functional but noncomplementing Drosophila tyrosine decarboxylase genes: distinct roles for neural tyramine and octopamine in female fertility.

The following Tdc1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tdc1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OFa09044	NM_136382.3 Latest version!	Drosophila melanogaster tyrosine decarboxylase 1 (Tdc1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Tdc1 ( NM_136382.3 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_610226.2 Drosophila melanogaster tyrosine decarboxylase 1 (Tdc1), mRNA.

Price & Availability↑

CloneID	OFa09044
Clone ID Related Accession (Same CDS sequence)	NM_136382.3
Accession Version	NM_136382.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1764bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	tyrosine decarboxylase 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033778). On Jan 16, 2013 this sequence version replaced NM_136382.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGATGTGG AAGAGTTTCG CAAATACGGC AAGGAAGTGA TTGATTATAT ATGCCAATAC 
GGCACTAATA TAGAGGAGCG TGACGTGGCG CCCACCTTGG ATCCGGGTTA CCTCAAAAAA 
CTGCTACCAG CCGACGCTCC CCAGTCGCCG GAGCCGTTCA AGGACGTGCT CGAGGACTTC 
GAGCAGAAGA TCATGCCGGG CGTGGTGCAC TGGAACCACC CCAAGTTCTT CGCCTACTTC 
CCCTCGGGCA ACTCTTTTCC ATCGGTCCTA GGCGACATGC TCAGCAGTGC CATTGGTTCA 
ATTGGCTTCA GCTGGGCCAG CTGTCCGGCG GCTGCCGAGC TGGAGACGAT CGTGATGAAC 
TGGTACGCCA AGGCCCTTGG CCTGCCCAAG GCCTTTGTTT CGGATGCCCC AGGCAGTACA 
GGCGGCGGCG CCCTTCAGGG ATCCGCCTCA GAGTGCGTTC TCGTCTCTCT AATCACAGCC 
CGCGCCCGGG CCATCAGCGA GCTAAAGGGT CAGACCAGCG TTCACGACAG CGTCTTCCTG 
CCCAGCCTGA TCGCATACGC CAGCCGTGAG GCACACTCCT CCGTGGAAAA GGCCACCAAG 
ATGGCCCTGG TGAAGCTCCG GATAATCGAT GCCGACGAGC ATGGACGCAT GCGCGTTGAC 
CTACTCCGCC AAGCAATTCA AAACGATGTG AACGCCGGCT TGACACCCTT CTTTGTAGTG 
GCCACTGTGG GTACCACCGG CGGCTGCGCT TTCGACGACA TCACGGAGAT CGGAAAGGTG 
TGCCGCCAGG TGTCGAGCAT TTGGCTGCAC GTAGACGGCG CCTATGCGGG AAACTCCTTC 
ATTCTGCCCG AGATGCGGGT CTTTTCGGCA GGACTCGAAT ACGCCGACTC CTTCAACACA 
AATCCCAACA AGCTTCTGCT GACGAACTTC GATGCCTCTG CCCTGTGGGT GCGGGATGTG 
ATGAACCTTA AGAGCGCGCT CAACGTGAAT CCCCTCTACC TACGACACGA GCACTTGACC 
GGAGTTGACT ACCGCCACTA CGGCATTCCC CTGAGTCGCC GATTCCGGGC ACTCAAGCTG 
TGGTTCGTCT TCCGGACATA CGGCATTCGG GGCCTACAGG AATACATTCG AAATCATATG 
GCGTTGGCTA AGAAGTTTGA GATGCTGGTG CGCAAGGATG AACGATTTGA GGTTCGCAAC 
GATGTTCACC TTGGCCTAGT TTGCTTCCGA ATGCGAACTG GCGACGAGCC CAACCACATG 
CTGCTCGCCC AGATCAACCA CTCGGGCAAG ATGCATATGA CGCCGGCCAA GTTCAACGGC 
CGCTACGTGA TCCGCTTCTG CGTCACCTAC GAGCACGCCA CTGAGAAGGA CATCCTGGAA 
GCTTGGACCC AGATAAAGTG CTTTGCTGAG GAAATACTGC GGGACCACCA GCTGGAGTCC 
AGCTCCGTGC CAACCACGCC GGAAGGCTCA GAGCGGACCA GCTCAGAGCC ATTGGCTCCA 
GTGGCGGGCA AGCCACCCAT CAAAAAGAGG CTGACCAGGA CAAAGTCGCT GCGATTCTCC 
TTCACTCGCA GCATCTCGCG GGAGCAGTAC CAGAGCCAGA GCGAGCACCT AATGGACGGG 
TGCACACCCA TCCTGGTCGT CGATCCCAAA ACTCTTCAGG AGAACTTCCA AAAGGCGGCG 
GATGACAATG ACAGGAACAA CAGCAATGGC AACGTAAAAC TCAAAGATAT ATCAGACGTG 
GATACGGACG AGGCGAGTAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_610226.2
CDS	213..1976
Translation	MDVEEFRKYGKEVIDYICQYGTNIEERDVAPTLDPGYLKKLLPADAPQSPEPFKDVLEDFEQKIMPGVVHWNHPKFFAYFPSGNSFPSVLGDMLSSAIGSIGFSWASCPAAAELETIVMNWYAKALGLPKAFVSDAPGSTGGGALQGSASECVLVSLITARARAISELKGQTSVHDSVFLPSLIAYASREAHSSVEKATKMALVKLRIIDADEHGRMRVDLLRQAIQNDVNAGLTPFFVVATVGTTGGCAFDDITEIGKVCRQVSSIWLHVDGAYAGNSFILPEMRVFSAGLEYADSFNTNPNKLLLTNFDASALWVRDVMNLKSALNVNPLYLRHEHLTGVDYRHYGIPLSRRFRALKLWFVFRTYGIRGLQEYIRNHMALAKKFEMLVRKDERFEVRNDVHLGLVCFRMRTGDEPNHMLLAQINHSGKMHMTPAKFNGRYVIRFCVTYEHATEKDILEAWTQIKCFAEEILRDHQLESSSVPTTPEGSERTSSEPLAPVAGKPPIKKRLTRTKSLRFSFTRSISREQYQSQSEHLMDGCTPILVVDPKTLQENFQKAADDNDRNNSNGNVKLKDISDVDTDEASN

Target ORF information:

RefSeq Version	NM_136382.3
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster tyrosine decarboxylase 1 (Tdc1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_136382.3

ORF Insert Sequence:

ATGGATGTGG AAGAGTTTCG CAAATACGGC AAGGAAGTGA TTGATTATAT ATGCCAATAC 
GGCACTAATA TAGAGGAGCG TGACGTGGCG CCCACCTTGG ATCCGGGTTA CCTCAAAAAA 
CTGCTACCAG CCGACGCTCC CCAGTCGCCG GAGCCGTTCA AGGACGTGCT CGAGGACTTC 
GAGCAGAAGA TCATGCCGGG CGTGGTGCAC TGGAACCACC CCAAGTTCTT CGCCTACTTC 
CCCTCGGGCA ACTCTTTTCC ATCGGTCCTA GGCGACATGC TCAGCAGTGC CATTGGTTCA 
ATTGGCTTCA GCTGGGCCAG CTGTCCGGCG GCTGCCGAGC TGGAGACGAT CGTGATGAAC 
TGGTACGCCA AGGCCCTTGG CCTGCCCAAG GCCTTTGTTT CGGATGCCCC AGGCAGTACA 
GGCGGCGGCG CCCTTCAGGG ATCCGCCTCA GAGTGCGTTC TCGTCTCTCT AATCACAGCC 
CGCGCCCGGG CCATCAGCGA GCTAAAGGGT CAGACCAGCG TTCACGACAG CGTCTTCCTG 
CCCAGCCTGA TCGCATACGC CAGCCGTGAG GCACACTCCT CCGTGGAAAA GGCCACCAAG 
ATGGCCCTGG TGAAGCTCCG GATAATCGAT GCCGACGAGC ATGGACGCAT GCGCGTTGAC 
CTACTCCGCC AAGCAATTCA AAACGATGTG AACGCCGGCT TGACACCCTT CTTTGTAGTG 
GCCACTGTGG GTACCACCGG CGGCTGCGCT TTCGACGACA TCACGGAGAT CGGAAAGGTG 
TGCCGCCAGG TGTCGAGCAT TTGGCTGCAC GTAGACGGCG CCTATGCGGG AAACTCCTTC 
ATTCTGCCCG AGATGCGGGT CTTTTCGGCA GGACTCGAAT ACGCCGACTC CTTCAACACA 
AATCCCAACA AGCTTCTGCT GACGAACTTC GATGCCTCTG CCCTGTGGGT GCGGGATGTG 
ATGAACCTTA AGAGCGCGCT CAACGTGAAT CCCCTCTACC TACGACACGA GCACTTGACC 
GGAGTTGACT ACCGCCACTA CGGCATTCCC CTGAGTCGCC GATTCCGGGC ACTCAAGCTG 
TGGTTCGTCT TCCGGACATA CGGCATTCGG GGCCTACAGG AATACATTCG AAATCATATG 
GCGTTGGCTA AGAAGTTTGA GATGCTGGTG CGCAAGGATG AACGATTTGA GGTTCGCAAC 
GATGTTCACC TTGGCCTAGT TTGCTTCCGA ATGCGAACTG GCGACGAGCC CAACCACATG 
CTGCTCGCCC AGATCAACCA CTCGGGCAAG ATGCATATGA CGCCGGCCAA GTTCAACGGC 
CGCTACGTGA TCCGCTTCTG CGTCACCTAC GAGCACGCCA CTGAGAAGGA CATCCTGGAA 
GCTTGGACCC AGATAAAGTG CTTTGCTGAG GAAATACTGC GGGACCACCA GCTGGAGTCC 
AGCTCCGTGC CAACCACGCC GGAAGGCTCA GAGCGGACCA GCTCAGAGCC ATTGGCTCCA 
GTGGCGGGCA AGCCACCCAT CAAAAAGAGG CTGACCAGGA CAAAGTCGCT GCGATTCTCC 
TTCACTCGCA GCATCTCGCG GGAGCAGTAC CAGAGCCAGA GCGAGCACCT AATGGACGGG 
TGCACACCCA TCCTGGTCGT CGATCCCAAA ACTCTTCAGG AGAACTTCCA AAAGGCGGCG 
GATGACAATG ACAGGAACAA CAGCAATGGC AACGTAAAAC TCAAAGATAT ATCAGACGTG 
GATACGGACG AGGCGAGTAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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Tdc1 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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