cni cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	cni
Entrez Gene ID	34967
Full Name	cornichon
Synonyms	BG:DS02740.13,CG5855,Cni,Dmel\CG5855,IV,anon-35Fe,spnG
General protein information	Preferred Names cornichon Names CG5855 gene product from transcript CG5855-RC CG5855-PA CG5855-PB CG5855-PC cni-PA cni-PB cni-PC spindle-G
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 2L Map Location: 35F1-35F1

mRNA and Protein(s)

mRNA	Protein	Name
NM_057720.3	NP_477068.1	cornichon, isoform B
NM_165151.2	NP_723959.1	cornichon, isoform A
NM_001273566.1	NP_001260495.1	cornichon, isoform C

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	CNIH	XP_509955.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008974	XP_319722.3
Xenopus tropicalis (tropical clawed frog)	cnih1	NP_001008067.1
	CNIH	XP_001085855.1
Mus musculus (house mouse)	Cnih1	NP_034049.2
Canis lupus familiaris (dog)	CNIH1	XP_003639247.2
Danio rerio (zebrafish)	cnih1	NP_001028278.1
Caenorhabditis elegans (roundworm)	cnih-2	NP_506278.1
Homo sapiens (human)	CNIH1	NP_005767.1
Bos taurus (cattle)	CNIH1	NP_001029911.1
Rattus norvegicus (Norway rat)	Cnih1	NP_001099499.1
Gallus gallus (chicken)	CNIH	NP_001028178.1
Drosophila melanogaster (fruit fly)	cni	NP_723959.1

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

human CNIH and Drosophila Cni are primarily localized in the endoplasmic reticulum and associate with immature TGFalpha family proteins; alterations of cornichon expression result in changes in transport, processing and secretion of TGFalpha proteins
Title: Cornichon regulates transport and secretion of TGFalpha-related proteins in metazoan cells.

Data show that Cornichon (Cni), but not Cni-related, binds to the extracellular domain of Gurken (Grk), and propose that Cni acts as a cargo receptor recruiting Grk into COPII vesicles.
Title: Drosophila Cornichon acts as cargo receptor for ER export of the TGFalpha-like growth factor Gurken.

The following cni gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the cni cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OFa14735	NM_057720.3 Latest version!	Drosophila melanogaster cornichon (cni), transcript variant B, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OFa14735	NM_165151.2 Latest version!	Drosophila melanogaster cornichon (cni), transcript variant A, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OFa14735	NM_001273566.1 Latest version!	Drosophila melanogaster cornichon (cni), transcript variant C, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

cni ( NM_057720.3 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_477068.1 Drosophila melanogaster cornichon (cni), transcript variant B, mRNA.

Price & Availability↑

CloneID	OFa14735
Clone ID Related Accession (Same CDS sequence)	NM_057720.3 , NM_165151.2 , NM_001273566.1
Accession Version	NM_057720.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 435bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	cornichon, isoform B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033779). On Jan 16, 2013 this sequence version replaced NM_057720.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGCCTTCA ACTTCACCGC CTTCACGTAC ATAGTGGCCC TGATCGGGGA TGCATTCTTG 
ATATTTTTCG CCATATTTCA TGTCATTGCA TTCGACGAAC TTAAAACGGA TTATAAGAAC 
CCAATTGATC AGTGCAATAG CCTCAATCCG CTGGTTTTGC CCGAATACCT TCTGCACATC 
TTTCTGAACT TGCTCTTCTT GTTCTGCGGC GAATGGTTTT CGCTATGCAT CAACATACCC 
CTCATAGCCT ATCATATTTG GCGTTACAAA AACCGCCCTG TGATGTCGGG ACCCGGACTT 
TATGATCCCA CCACGGTCCT GAAAACCGAT ACTTTGTACC GGAACATGCG TGAGGGTTGG 
ATTAAACTGG CCGTCTATCT GATTAGCTTC TTCTACTACA TATACGGCAT GGTTTATTCG 
CTCATCTCGA CATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_477068.1
CDS	137..571
Translation	MAFNFTAFTYIVALIGDAFLIFFAIFHVIAFDELKTDYKNPIDQCNSLNPLVLPEYLLHIFLNLLFLFCGEWFSLCINIPLIAYHIWRYKNRPVMSGPGLYDPTTVLKTDTLYRNMREGWIKLAVYLISFFYYIYGMVYSLIST

Target ORF information:

RefSeq Version	NM_057720.3
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster cornichon (cni), transcript variant B, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_057720.3

ORF Insert Sequence:

ATGGCCTTCA ACTTCACCGC CTTCACGTAC ATAGTGGCCC TGATCGGGGA TGCATTCTTG 
ATATTTTTCG CCATATTTCA TGTCATTGCA TTCGACGAAC TTAAAACGGA TTATAAGAAC 
CCAATTGATC AGTGCAATAG CCTCAATCCG CTGGTTTTGC CCGAATACCT TCTGCACATC 
TTTCTGAACT TGCTCTTCTT GTTCTGCGGC GAATGGTTTT CGCTATGCAT CAACATACCC 
CTCATAGCCT ATCATATTTG GCGTTACAAA AACCGCCCTG TGATGTCGGG ACCCGGACTT 
TATGATCCCA CCACGGTCCT GAAAACCGAT ACTTTGTACC GGAACATGCG TGAGGGTTGG 
ATTAAACTGG CCGTCTATCT GATTAGCTTC TTCTACTACA TATACGGCAT GGTTTATTCG 
CTCATCTCGA CATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

cni ( NM_165151.2 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_723959.1 Drosophila melanogaster cornichon (cni), transcript variant A, mRNA.

Price & Availability↑

CloneID	OFa14735
Clone ID Related Accession (Same CDS sequence)	NM_057720.3 , NM_165151.2 , NM_001273566.1
Accession Version	NM_165151.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 435bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	cornichon, isoform A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033779). On Jan 16, 2013 this sequence version replaced NM_165151.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGCCTTCA ACTTCACCGC CTTCACGTAC ATAGTGGCCC TGATCGGGGA TGCATTCTTG 
ATATTTTTCG CCATATTTCA TGTCATTGCA TTCGACGAAC TTAAAACGGA TTATAAGAAC 
CCAATTGATC AGTGCAATAG CCTCAATCCG CTGGTTTTGC CCGAATACCT TCTGCACATC 
TTTCTGAACT TGCTCTTCTT GTTCTGCGGC GAATGGTTTT CGCTATGCAT CAACATACCC 
CTCATAGCCT ATCATATTTG GCGTTACAAA AACCGCCCTG TGATGTCGGG ACCCGGACTT 
TATGATCCCA CCACGGTCCT GAAAACCGAT ACTTTGTACC GGAACATGCG TGAGGGTTGG 
ATTAAACTGG CCGTCTATCT GATTAGCTTC TTCTACTACA TATACGGCAT GGTTTATTCG 
CTCATCTCGA CATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_723959.1
CDS	70..504
Translation	MAFNFTAFTYIVALIGDAFLIFFAIFHVIAFDELKTDYKNPIDQCNSLNPLVLPEYLLHIFLNLLFLFCGEWFSLCINIPLIAYHIWRYKNRPVMSGPGLYDPTTVLKTDTLYRNMREGWIKLAVYLISFFYYIYGMVYSLIST

Target ORF information:

RefSeq Version	NM_165151.2
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster cornichon (cni), transcript variant A, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_165151.2

ORF Insert Sequence:

ATGGCCTTCA ACTTCACCGC CTTCACGTAC ATAGTGGCCC TGATCGGGGA TGCATTCTTG 
ATATTTTTCG CCATATTTCA TGTCATTGCA TTCGACGAAC TTAAAACGGA TTATAAGAAC 
CCAATTGATC AGTGCAATAG CCTCAATCCG CTGGTTTTGC CCGAATACCT TCTGCACATC 
TTTCTGAACT TGCTCTTCTT GTTCTGCGGC GAATGGTTTT CGCTATGCAT CAACATACCC 
CTCATAGCCT ATCATATTTG GCGTTACAAA AACCGCCCTG TGATGTCGGG ACCCGGACTT 
TATGATCCCA CCACGGTCCT GAAAACCGAT ACTTTGTACC GGAACATGCG TGAGGGTTGG 
ATTAAACTGG CCGTCTATCT GATTAGCTTC TTCTACTACA TATACGGCAT GGTTTATTCG 
CTCATCTCGA CATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

cni ( NM_001273566.1 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_001260495.1 Drosophila melanogaster cornichon (cni), transcript variant C, mRNA.

Price & Availability↑

CloneID	OFa14735
Clone ID Related Accession (Same CDS sequence)	NM_057720.3 , NM_165151.2 , NM_001273566.1
Accession Version	NM_001273566.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 435bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	cornichon, isoform C
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033779). ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGCCTTCA ACTTCACCGC CTTCACGTAC ATAGTGGCCC TGATCGGGGA TGCATTCTTG 
ATATTTTTCG CCATATTTCA TGTCATTGCA TTCGACGAAC TTAAAACGGA TTATAAGAAC 
CCAATTGATC AGTGCAATAG CCTCAATCCG CTGGTTTTGC CCGAATACCT TCTGCACATC 
TTTCTGAACT TGCTCTTCTT GTTCTGCGGC GAATGGTTTT CGCTATGCAT CAACATACCC 
CTCATAGCCT ATCATATTTG GCGTTACAAA AACCGCCCTG TGATGTCGGG ACCCGGACTT 
TATGATCCCA CCACGGTCCT GAAAACCGAT ACTTTGTACC GGAACATGCG TGAGGGTTGG 
ATTAAACTGG CCGTCTATCT GATTAGCTTC TTCTACTACA TATACGGCAT GGTTTATTCG 
CTCATCTCGA CATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001260495.1
CDS	87..521
Translation	MAFNFTAFTYIVALIGDAFLIFFAIFHVIAFDELKTDYKNPIDQCNSLNPLVLPEYLLHIFLNLLFLFCGEWFSLCINIPLIAYHIWRYKNRPVMSGPGLYDPTTVLKTDTLYRNMREGWIKLAVYLISFFYYIYGMVYSLIST

Target ORF information:

RefSeq Version	NM_001273566.1
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster cornichon (cni), transcript variant C, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001273566.1

ORF Insert Sequence:

ATGGCCTTCA ACTTCACCGC CTTCACGTAC ATAGTGGCCC TGATCGGGGA TGCATTCTTG 
ATATTTTTCG CCATATTTCA TGTCATTGCA TTCGACGAAC TTAAAACGGA TTATAAGAAC 
CCAATTGATC AGTGCAATAG CCTCAATCCG CTGGTTTTGC CCGAATACCT TCTGCACATC 
TTTCTGAACT TGCTCTTCTT GTTCTGCGGC GAATGGTTTT CGCTATGCAT CAACATACCC 
CTCATAGCCT ATCATATTTG GCGTTACAAA AACCGCCCTG TGATGTCGGG ACCCGGACTT 
TATGATCCCA CCACGGTCCT GAAAACCGAT ACTTTGTACC GGAACATGCG TGAGGGTTGG 
ATTAAACTGG CCGTCTATCT GATTAGCTTC TTCTACTACA TATACGGCAT GGTTTATTCG 
CTCATCTCGA CATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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cni cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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