Rab6 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	Rab6
Entrez Gene ID	34636
Full Name	CG6601 gene product from transcript CG6601-RB
Synonyms	136/6,AAF53168,CG6601,DRab6,Dm Rab6,DmRab6,Dmel\CG6601,Drab6,O18334,dRab6,drab6,l(2)08323,rab6,wrt
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 2L Map Location: 33C4-33C4

mRNA and Protein(s)

mRNA	Protein	Name
NM_057824.5	NP_477172.1	Rab6, isoform A
NM_001298940.1	NP_001285869.1	Rab6, isoform B

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	LOC100610924	XP_003309297.1
Bos taurus (cattle)	RAB6A	NP_001180044.1
Arabidopsis thaliana (thale cress)	RABH1e	NP_196588.3
Arabidopsis thaliana (thale cress)	RABH1c	NP_195699.1
Xenopus tropicalis (tropical clawed frog)	rab6a	NP_989315.1
Pan troglodytes (chimpanzee)	LOC459601	XP_003954210.1
Canis lupus familiaris (dog)	LOC608330	XP_003639844.2
Danio rerio (zebrafish)	zgc:112018	NP_001013485.1
Drosophila melanogaster (fruit fly)	Rab6	NP_477172.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP011363	XP_001238010.2
Arabidopsis thaliana (thale cress)	RABH1d	NP_179816.1
Caenorhabditis elegans (roundworm)	rab-6.2	NP_510790.1

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Rab6 regulates apical cargo trafficking from the trans-Golgi network to recycling endosomes in fly photoreceptors.
Title: Rab6 functions in polarized transport in Drosophila photoreceptors.

Rab6 is required for multiple apical transport pathways but not the basolateral transport pathway in Drosophila photoreceptors.Rab6 is essential for the trans-Golgi network-recycling endosome transport.
Title: Rab6 Is Required for Multiple Apical Transport Pathways but Not the Basolateral Transport Pathway in Drosophila Photoreceptors.

Novel molecular events in the regulation of phagocytosis of infecting viruses by Rab6.
Title: Involvement of Rab6 in the regulation of phagocytosis against virus infection in invertebrates.

Rab6 localizes to Golgi and Golgi-derived membranes and interacts with BicD in establishing cell polarity during oogenesis.
Title: Rab6 and the secretory pathway affect oocyte polarity in Drosophila.

Rab6 mediates membrane organization and determinant localization during Drosophila oogenesis.
Title: Rab6 mediates membrane organization and determinant localization during Drosophila oogenesis.

The following Rab6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rab6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OFa14512	NM_001298940.1 Latest version!	Drosophila melanogaster Rab6, transcript variant B (Rab6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00
OFa14512	NM_057824.5 Latest version!	Drosophila melanogaster Rab6, transcript variant A (Rab6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Rab6 ( NM_057824.5 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_477172.1 Drosophila melanogaster Rab6, transcript variant A (Rab6), mRNA.

Price & Availability↑

CloneID	OFa14512
Clone ID Related Accession (Same CDS sequence)	NM_057824.5 , NM_001298940.1
Accession Version	NM_057824.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 627bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	Rab6, isoform A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033779). On Jul 15, 2014 this sequence version replaced NM_057824.4. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGTCATCCG GAGATTTTGG CAATCCGCTG CGGAAGTTCA AGCTCGTCTT CCTCGGCGAG 
CAGAGTGTGG GCAAGACCTC GCTGATTACG CGCTTCATGT ACGACAGCTT CGACAACACG 
TACCAGGCGA CGATCGGAAT TGATTTCCTA TCGAAGACCA TGTACCTGGA GGATCGCACT 
GTGCGCCTGC AGCTGTGGGA TACGGCGGGA CAGGAGCGAT TCCGCTCGCT GATACCCTCG 
TACATACGCG ACTCCACGGT GGCAGTGGTC GTTTACGATA TCACCAACAC CAACTCGTTC 
CACCAGACCT CCAAGTGGAT CGATGACGTG CGCACGGAGC GGGGTAGCGA CGTCATCATC 
ATGCTGGTGG GCAACAAGAC GGATCTCTCC GACAAGCGTC AGGTGTCCAC CGAGGAGGGT 
GAGCGCAAGG CGAAGGAGCT TAACGTGATG TTCATCGAGA CAAGCGCCAA GGCCGGCTAC 
AATGTGAAGC AATTGTTCCG ACGGGTGGCC GCGGCACTGC CCGGCATGGA TTCCACGGAG 
AACAAGCCCT CCGAGGACAT GCAGGAGGTT GTGCTAAAGG ACTCACCCAA CGAGACAAAG 
GATCCCGAGG GCGGCTGCGC CTGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_477172.1
CDS	318..944
Translation	MSSGDFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNTNSFHQTSKWIDDVRTERGSDVIIMLVGNKTDLSDKRQVSTEEGERKAKELNVMFIETSAKAGYNVKQLFRRVAAALPGMDSTENKPSEDMQEVVLKDSPNETKDPEGGCAC

Target ORF information:

RefSeq Version	NM_057824.5
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster Rab6, transcript variant A (Rab6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_057824.5

ORF Insert Sequence:

ATGTCATCCG GAGATTTTGG CAATCCGCTG CGGAAGTTCA AGCTCGTCTT CCTCGGCGAG 
CAGAGTGTGG GCAAGACCTC GCTGATTACG CGCTTCATGT ACGACAGCTT CGACAACACG 
TACCAGGCGA CGATCGGAAT TGATTTCCTA TCGAAGACCA TGTACCTGGA GGATCGCACT 
GTGCGCCTGC AGCTGTGGGA TACGGCGGGA CAGGAGCGAT TCCGCTCGCT GATACCCTCG 
TACATACGCG ACTCCACGGT GGCAGTGGTC GTTTACGATA TCACCAACAC CAACTCGTTC 
CACCAGACCT CCAAGTGGAT CGATGACGTG CGCACGGAGC GGGGTAGCGA CGTCATCATC 
ATGCTGGTGG GCAACAAGAC GGATCTCTCC GACAAGCGTC AGGTGTCCAC CGAGGAGGGT 
GAGCGCAAGG CGAAGGAGCT TAACGTGATG TTCATCGAGA CAAGCGCCAA GGCCGGCTAC 
AATGTGAAGC AATTGTTCCG ACGGGTGGCC GCGGCACTGC CCGGCATGGA TTCCACGGAG 
AACAAGCCCT CCGAGGACAT GCAGGAGGTT GTGCTAAAGG ACTCACCCAA CGAGACAAAG 
GATCCCGAGG GCGGCTGCGC CTGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rab6 ( NM_001298940.1 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_001285869.1 Drosophila melanogaster Rab6, transcript variant B (Rab6), mRNA.

Price & Availability↑

CloneID	OFa14512
Clone ID Related Accession (Same CDS sequence)	NM_057824.5 , NM_001298940.1
Accession Version	NM_001298940.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 627bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	Rab6, isoform B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033779). ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGTCATCCG GAGATTTTGG CAATCCGCTG CGGAAGTTCA AGCTCGTCTT CCTCGGCGAG 
CAGAGTGTGG GCAAGACCTC GCTGATTACG CGCTTCATGT ACGACAGCTT CGACAACACG 
TACCAGGCGA CGATCGGAAT TGATTTCCTA TCGAAGACCA TGTACCTGGA GGATCGCACT 
GTGCGCCTGC AGCTGTGGGA TACGGCGGGA CAGGAGCGAT TCCGCTCGCT GATACCCTCG 
TACATACGCG ACTCCACGGT GGCAGTGGTC GTTTACGATA TCACCAACAC CAACTCGTTC 
CACCAGACCT CCAAGTGGAT CGATGACGTG CGCACGGAGC GGGGTAGCGA CGTCATCATC 
ATGCTGGTGG GCAACAAGAC GGATCTCTCC GACAAGCGTC AGGTGTCCAC CGAGGAGGGT 
GAGCGCAAGG CGAAGGAGCT TAACGTGATG TTCATCGAGA CAAGCGCCAA GGCCGGCTAC 
AATGTGAAGC AATTGTTCCG ACGGGTGGCC GCGGCACTGC CCGGCATGGA TTCCACGGAG 
AACAAGCCCT CCGAGGACAT GCAGGAGGTT GTGCTAAAGG ACTCACCCAA CGAGACAAAG 
GATCCCGAGG GCGGCTGCGC CTGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001285869.1
CDS	318..944
Translation	MSSGDFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNTNSFHQTSKWIDDVRTERGSDVIIMLVGNKTDLSDKRQVSTEEGERKAKELNVMFIETSAKAGYNVKQLFRRVAAALPGMDSTENKPSEDMQEVVLKDSPNETKDPEGGCAC

Target ORF information:

RefSeq Version	NM_001298940.1
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster Rab6, transcript variant B (Rab6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001298940.1

ORF Insert Sequence:

ATGTCATCCG GAGATTTTGG CAATCCGCTG CGGAAGTTCA AGCTCGTCTT CCTCGGCGAG 
CAGAGTGTGG GCAAGACCTC GCTGATTACG CGCTTCATGT ACGACAGCTT CGACAACACG 
TACCAGGCGA CGATCGGAAT TGATTTCCTA TCGAAGACCA TGTACCTGGA GGATCGCACT 
GTGCGCCTGC AGCTGTGGGA TACGGCGGGA CAGGAGCGAT TCCGCTCGCT GATACCCTCG 
TACATACGCG ACTCCACGGT GGCAGTGGTC GTTTACGATA TCACCAACAC CAACTCGTTC 
CACCAGACCT CCAAGTGGAT CGATGACGTG CGCACGGAGC GGGGTAGCGA CGTCATCATC 
ATGCTGGTGG GCAACAAGAC GGATCTCTCC GACAAGCGTC AGGTGTCCAC CGAGGAGGGT 
GAGCGCAAGG CGAAGGAGCT TAACGTGATG TTCATCGAGA CAAGCGCCAA GGCCGGCTAC 
AATGTGAAGC AATTGTTCCG ACGGGTGGCC GCGGCACTGC CCGGCATGGA TTCCACGGAG 
AACAAGCCCT CCGAGGACAT GCAGGAGGTT GTGCTAAAGG ACTCACCCAA CGAGACAAAG 
GATCCCGAGG GCGGCTGCGC CTGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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Rab6 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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