IP3K1 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	IP3K1
Entrez Gene ID	34300
Full Name	Inositol 1,4,5-triphosphate kinase 1
Synonyms	CG4026,D-IP3K1,Dmel\CG4026,IP3KI,IP[[3]]K-1,UY530,anon-WO0118547.189,dmIP3Kalpha,dmIP[[3]]Kalpha
General protein information	Preferred Names Inositol 1,4,5-triphosphate kinase 1 Names CG4026 gene product from transcript CG4026-RA CG4026-PA CG4026-PB IP3 kinase 1 IP3K1-PA IP3K1-PB inositol 1,4,5-triphosphate kinase 1 inositol 1,4,5-triphosphate kinase1
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 2L Map Location: 30C9-30D1

mRNA and Protein(s)

mRNA	Protein	Name
NM_001259025.1	NP_001245954.1	inositol 1,4,5-triphosphate kinase 1, isoform B
NM_135469.4	NP_609313.2	inositol 1,4,5-triphosphate kinase 1, isoform A

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

IP(3)K-1 modulates epithelial cell apoptosis without involvement of bcl-2-type proteins.
Title: Cell-specific inositol 1,4,5 trisphosphate 3-kinase mediates epithelial cell apoptosis in response to oxidative stress in Drosophila.

the major route of IP6 synthesis depends on the activities of dmIpk2 and dmIpk1, but not dmIP3K, offering a new role for IP3K in the genesis of higher IP messengers
Title: A molecular basis for inositol polyphosphate synthesis in Drosophila melanogaster.

The following IP3K1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IP3K1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OFa14230	NM_135469.4 Latest version!	Drosophila melanogaster inositol 1,4,5-triphosphate kinase 1, transcript variant A (IP3K1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00
OFa15961	NM_001259025.1 Latest version!	Drosophila melanogaster inositol 1,4,5-triphosphate kinase 1, transcript variant B (IP3K1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

IP3K1 ( NM_135469.4 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_609313.2 Drosophila melanogaster inositol 1,4,5-triphosphate kinase 1, transcript variant A (IP3K1), mRNA.

Price & Availability↑

CloneID	OFa14230
Clone ID Related Accession (Same CDS sequence)	NM_135469.4
Accession Version	NM_135469.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1326bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	inositol 1,4,5-triphosphate kinase 1, isoform A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033779). On Jan 16, 2013 this sequence version replaced NM_135469.3. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGACTATGA CTTCTACGGT GCTCCAACGG CCCATTCAAG CCAAGCCAGA GAAGAAGGCC 
TCCTCCAAAT CGACCAGCTC CTCGAGAAGC CGCTCCACGA TGGCCTGGTC CAATGAGAAG 
CTGCGCTTCT CCTGCATCGA CAACATCGGA CTCAAGCAGC TATGGAAGCT GATTGCCCTG 
GACACGAGTG CTTCATCCAA GCAGCGCAGT GCCATGATGT TGGAAGTGGA GCAACAGCAG 
CAACAGCAGC AGCAGCAGCA ATCGAACAAC AATAACGAGC GGATACCCAA CGAGAACTGC 
GACTATTTGA GTCTACAGAG ATCGGGCCAG GCGCCGAAGA ATCACATCCA GGCGCAGGAT 
CCGGCTCAGA TGTCCCTGCT CAAGTTCTTG GCCATTAATG CCCTAGAGCT GAGTGCCCCA 
GCAACGCCAC ATCTCCTCCA GCATCAGCAG GCCCACAAGC AGGCGAAGCC ACAGGGCTGG 
ATGCAGCTAT CCGGTCACCC AGAGAGCATT GTTCCCACAT CGACTGGAAT AGTGCGCAAA 
CGGATCTCAG GACTGGAGGA TAGCGAAGTA CATGCCTACC GACTGATCTG CAAGGAACCA 
CAGACCGCTC AGATAGTGCC CGCCTACTTT GGAATACAGG AGATGCAATC ACAGCACTTT 
ATTGAGCTGC AGGATCTGCT GGCTGGCTTT CGGGATCCGT GTGTGATGGA CATCAAGATG 
GGCAGCCGCA CCTTTCTCGA ATCGGAGGTC AGCAATGCCA CGCTCAGACC GGACCTCTAC 
CAGAAGATGA TCGCCGTGGA TGCGGGAGCT CCCACGCCTG CGGAGCACGA GGCACGAGCG 
ATCACCAAGC TGCGGTACAT GACATTCCGG GAGTCCCTGT CCTCCTCCCA CTCCAAGGGT 
TTCCGGATCG AAGCACTGCG TCTGCGCGGA CGACCGCCTG TCAAGGATTT GAAGACGTGC 
CGAAGCAGCG AGCAGATTGC CCAGACGATC GAACAGTTTC TGGCTGCTCG GCGATCCGTG 
CAAAAGGAGC TGCTGAAGCG ACTAAAGCAC ATGCGCCTGG TCATCGAACA GTCGACCTTC 
TTCGCCAGCC ACGAGATCAT TGGCTCCAGC ATCTTTATCG TCTACGATGA CGATCGCGTT 
GGCGTTTGGC TAATTGACTT CGCCAAGTGC CGGGAGCTGC CACCCCATGT GAGGGTGGAC 
CATCGAAGTG CTTGGGCGCC TGGAAACCGA GAGGAGGGTC TGCTACGCGG AATGGACGAG 
CTCATCCGCT CCTTCGAGGA GGTCTACGCC CGCTGTGGCT CCCATCGCAG CTGCCTTAAA 
ATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_609313.2
CDS	402..1727
Translation	MTMTSTVLQRPIQAKPEKKASSKSTSSSRSRSTMAWSNEKLRFSCIDNIGLKQLWKLIALDTSASSKQRSAMMLEVEQQQQQQQQQQSNNNNERIPNENCDYLSLQRSGQAPKNHIQAQDPAQMSLLKFLAINALELSAPATPHLLQHQQAHKQAKPQGWMQLSGHPESIVPTSTGIVRKRISGLEDSEVHAYRLICKEPQTAQIVPAYFGIQEMQSQHFIELQDLLAGFRDPCVMDIKMGSRTFLESEVSNATLRPDLYQKMIAVDAGAPTPAEHEARAITKLRYMTFRESLSSSHSKGFRIEALRLRGRPPVKDLKTCRSSEQIAQTIEQFLAARRSVQKELLKRLKHMRLVIEQSTFFASHEIIGSSIFIVYDDDRVGVWLIDFAKCRELPPHVRVDHRSAWAPGNREEGLLRGMDELIRSFEEVYARCGSHRSCLKI

Target ORF information:

RefSeq Version	NM_135469.4
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster inositol 1,4,5-triphosphate kinase 1, transcript variant A (IP3K1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_135469.4

ORF Insert Sequence:

ATGACTATGA CTTCTACGGT GCTCCAACGG CCCATTCAAG CCAAGCCAGA GAAGAAGGCC 
TCCTCCAAAT CGACCAGCTC CTCGAGAAGC CGCTCCACGA TGGCCTGGTC CAATGAGAAG 
CTGCGCTTCT CCTGCATCGA CAACATCGGA CTCAAGCAGC TATGGAAGCT GATTGCCCTG 
GACACGAGTG CTTCATCCAA GCAGCGCAGT GCCATGATGT TGGAAGTGGA GCAACAGCAG 
CAACAGCAGC AGCAGCAGCA ATCGAACAAC AATAACGAGC GGATACCCAA CGAGAACTGC 
GACTATTTGA GTCTACAGAG ATCGGGCCAG GCGCCGAAGA ATCACATCCA GGCGCAGGAT 
CCGGCTCAGA TGTCCCTGCT CAAGTTCTTG GCCATTAATG CCCTAGAGCT GAGTGCCCCA 
GCAACGCCAC ATCTCCTCCA GCATCAGCAG GCCCACAAGC AGGCGAAGCC ACAGGGCTGG 
ATGCAGCTAT CCGGTCACCC AGAGAGCATT GTTCCCACAT CGACTGGAAT AGTGCGCAAA 
CGGATCTCAG GACTGGAGGA TAGCGAAGTA CATGCCTACC GACTGATCTG CAAGGAACCA 
CAGACCGCTC AGATAGTGCC CGCCTACTTT GGAATACAGG AGATGCAATC ACAGCACTTT 
ATTGAGCTGC AGGATCTGCT GGCTGGCTTT CGGGATCCGT GTGTGATGGA CATCAAGATG 
GGCAGCCGCA CCTTTCTCGA ATCGGAGGTC AGCAATGCCA CGCTCAGACC GGACCTCTAC 
CAGAAGATGA TCGCCGTGGA TGCGGGAGCT CCCACGCCTG CGGAGCACGA GGCACGAGCG 
ATCACCAAGC TGCGGTACAT GACATTCCGG GAGTCCCTGT CCTCCTCCCA CTCCAAGGGT 
TTCCGGATCG AAGCACTGCG TCTGCGCGGA CGACCGCCTG TCAAGGATTT GAAGACGTGC 
CGAAGCAGCG AGCAGATTGC CCAGACGATC GAACAGTTTC TGGCTGCTCG GCGATCCGTG 
CAAAAGGAGC TGCTGAAGCG ACTAAAGCAC ATGCGCCTGG TCATCGAACA GTCGACCTTC 
TTCGCCAGCC ACGAGATCAT TGGCTCCAGC ATCTTTATCG TCTACGATGA CGATCGCGTT 
GGCGTTTGGC TAATTGACTT CGCCAAGTGC CGGGAGCTGC CACCCCATGT GAGGGTGGAC 
CATCGAAGTG CTTGGGCGCC TGGAAACCGA GAGGAGGGTC TGCTACGCGG AATGGACGAG 
CTCATCCGCT CCTTCGAGGA GGTCTACGCC CGCTGTGGCT CCCATCGCAG CTGCCTTAAA 
ATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IP3K1 ( NM_001259025.1 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_001245954.1 Drosophila melanogaster inositol 1,4,5-triphosphate kinase 1, transcript variant B (IP3K1), mRNA.

Price & Availability↑

CloneID	OFa15961
Clone ID Related Accession (Same CDS sequence)	NM_001259025.1
Accession Version	NM_001259025.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 957bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	inositol 1,4,5-triphosphate kinase 1, isoform B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033779). ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGTCCCTGC TCAAGTTCTT GGCCATTAAT GCCCTAGAGC TGAGTGCCCC AGCAACGCCA 
CATCTCCTCC AGCATCAGCA GGCCCACAAG CAGGCGAAGC CACAGGGCTG GATGCAGCTA 
TCCGGTCACC CAGAGAGCAT TGTTCCCACA TCGACTGGAA TAGTGCGCAA ACGGATCTCA 
GGACTGGAGG ATAGCGAAGT ACATGCCTAC CGACTGATCT GCAAGGAACC ACAGACCGCT 
CAGATAGTGC CCGCCTACTT TGGAATACAG GAGATGCAAT CACAGCACTT TATTGAGCTG 
CAGGATCTGC TGGCTGGCTT TCGGGATCCG TGTGTGATGG ACATCAAGAT GGGCAGCCGC 
ACCTTTCTCG AATCGGAGGT CAGCAATGCC ACGCTCAGAC CGGACCTCTA CCAGAAGATG 
ATCGCCGTGG ATGCGGGAGC TCCCACGCCT GCGGAGCACG AGGCACGAGC GATCACCAAG 
CTGCGGTACA TGACATTCCG GGAGTCCCTG TCCTCCTCCC ACTCCAAGGG TTTCCGGATC 
GAAGCACTGC GTCTGCGCGG ACGACCGCCT GTCAAGGATT TGAAGACGTG CCGAAGCAGC 
GAGCAGATTG CCCAGACGAT CGAACAGTTT CTGGCTGCTC GGCGATCCGT GCAAAAGGAG 
CTGCTGAAGC GACTAAAGCA CATGCGCCTG GTCATCGAAC AGTCGACCTT CTTCGCCAGC 
CACGAGATCA TTGGCTCCAG CATCTTTATC GTCTACGATG ACGATCGCGT TGGCGTTTGG 
CTAATTGACT TCGCCAAGTG CCGGGAGCTG CCACCCCATG TGAGGGTGGA CCATCGAAGT 
GCTTGGGCGC CTGGAAACCG AGAGGAGGGT CTGCTACGCG GAATGGACGA GCTCATCCGC 
TCCTTCGAGG AGGTCTACGC CCGCTGTGGC TCCCATCGCA GCTGCCTTAA AATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001245954.1
CDS	133..1089
Translation	MSLLKFLAINALELSAPATPHLLQHQQAHKQAKPQGWMQLSGHPESIVPTSTGIVRKRISGLEDSEVHAYRLICKEPQTAQIVPAYFGIQEMQSQHFIELQDLLAGFRDPCVMDIKMGSRTFLESEVSNATLRPDLYQKMIAVDAGAPTPAEHEARAITKLRYMTFRESLSSSHSKGFRIEALRLRGRPPVKDLKTCRSSEQIAQTIEQFLAARRSVQKELLKRLKHMRLVIEQSTFFASHEIIGSSIFIVYDDDRVGVWLIDFAKCRELPPHVRVDHRSAWAPGNREEGLLRGMDELIRSFEEVYARCGSHRSCLKI

Target ORF information:

RefSeq Version	NM_001259025.1
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster inositol 1,4,5-triphosphate kinase 1, transcript variant B (IP3K1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001259025.1

ORF Insert Sequence:

ATGTCCCTGC TCAAGTTCTT GGCCATTAAT GCCCTAGAGC TGAGTGCCCC AGCAACGCCA 
CATCTCCTCC AGCATCAGCA GGCCCACAAG CAGGCGAAGC CACAGGGCTG GATGCAGCTA 
TCCGGTCACC CAGAGAGCAT TGTTCCCACA TCGACTGGAA TAGTGCGCAA ACGGATCTCA 
GGACTGGAGG ATAGCGAAGT ACATGCCTAC CGACTGATCT GCAAGGAACC ACAGACCGCT 
CAGATAGTGC CCGCCTACTT TGGAATACAG GAGATGCAAT CACAGCACTT TATTGAGCTG 
CAGGATCTGC TGGCTGGCTT TCGGGATCCG TGTGTGATGG ACATCAAGAT GGGCAGCCGC 
ACCTTTCTCG AATCGGAGGT CAGCAATGCC ACGCTCAGAC CGGACCTCTA CCAGAAGATG 
ATCGCCGTGG ATGCGGGAGC TCCCACGCCT GCGGAGCACG AGGCACGAGC GATCACCAAG 
CTGCGGTACA TGACATTCCG GGAGTCCCTG TCCTCCTCCC ACTCCAAGGG TTTCCGGATC 
GAAGCACTGC GTCTGCGCGG ACGACCGCCT GTCAAGGATT TGAAGACGTG CCGAAGCAGC 
GAGCAGATTG CCCAGACGAT CGAACAGTTT CTGGCTGCTC GGCGATCCGT GCAAAAGGAG 
CTGCTGAAGC GACTAAAGCA CATGCGCCTG GTCATCGAAC AGTCGACCTT CTTCGCCAGC 
CACGAGATCA TTGGCTCCAG CATCTTTATC GTCTACGATG ACGATCGCGT TGGCGTTTGG 
CTAATTGACT TCGCCAAGTG CCGGGAGCTG CCACCCCATG TGAGGGTGGA CCATCGAAGT 
GCTTGGGCGC CTGGAAACCG AGAGGAGGGT CTGCTACGCG GAATGGACGA GCTCATCCGC 
TCCTTCGAGG AGGTCTACGC CCGCTGTGGC TCCCATCGCA GCTGCCTTAA AATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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IP3K1 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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