SLC5A11 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	SLC5A11
Entrez Gene ID	34117
Full Name	Sodium/solute co-transporter-like 5A11
Synonyms	CG8451,CG8451-PA,Dmel\CG8451
General protein information	Preferred Names Sodium/solute co-transporter-like 5A11 Names CG8451 gene product from transcript CG8451-RA CG8451-PA NA-dependent multivitamin transporter SLC5A11-PA cupcake
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 2L Map Location: 28F1-28F1

mRNA and Protein(s)

mRNA	Protein	Name
NM_135348.3	NP_609192.1	Sodium/solute co-transporter-like 5A11

Pathways from BioSystems

Homologies

Drosophila melanogaster (fruit fly)	CG8451	NP_609192.1
Drosophila melanogaster (fruit fly)	CG33124	NP_001097056.3
Drosophila melanogaster (fruit fly)	CG31262	NP_732222.2
Drosophila melanogaster (fruit fly)	CG31668	NP_001097055.2

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The excitability of SLC5A11-expressing EB R4 neurons increases dramatically during starvation and this increase is abolished in the SLC5A11 mutation. Artificial activation of SLC5A11-expresssing neurons is sufficient to promote feeding and hunger-driven behaviors; silencing these neurons has the opposite effect.
Title: Drosophila SLC5A11 Mediates Hunger by Regulating K(+) Channel Activity.

The following SLC5A11 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SLC5A11 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OFa14097	NM_135348.3 Latest version!	Drosophila melanogaster Sodium/solute co-transporter-like 5A11 (SLC5A11), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SLC5A11 ( NM_135348.3 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_609192.1 Drosophila melanogaster Sodium/solute co-transporter-like 5A11 (SLC5A11), mRNA.

Price & Availability↑

CloneID	OFa14097
Clone ID Related Accession (Same CDS sequence)	NM_135348.3
Accession Version	NM_135348.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1803bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	Sodium/solute co-transporter-like 5A11
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033779). On Jan 16, 2013 this sequence version replaced NM_135348.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGAAGCGG TGGCAAAGAA GGGCATGGAG AACTACAGAT TTGGCAGTGT GGACTATGCC 
GTTTTCCTGG GCATGATCGT ATTATCCACC AGCACGGGCA TCTATTTCGG GTGCATCAAG 
AAGAGCAAGG TGAAGCTCGA GGAGGCGGAA CCCACTCTGC CGACGACCAC GCCAAAAAGG 
CGGAAACACG ATTTCGGATC GGAGAAGATG AGCGAGTATC TGCTAGGGTC ACGCAATCTG 
AAAGTTTTCC CCGTTGCCAT GAGCCTGATA GCCAGCTATA TATCGGGCGT TACCATACTG 
GGCACAACCT CTGAGATCTA CAATTATGGC ACGCAATATT GGTTTATAGC CATAGCAATA 
ATGCTCCAAG GTATTGCCGT CTCCTACGTC TACATACCAG TGTTCTCGGC TCTTCAAGTA 
GGCTCTTCCT ATGAGTACTT GGAGATGCGC TTTCATTCGG TCGTACGAAG TATTGCATCC 
TTTATGTTTA TTCTGGATGA GATTCTGTTT CTGCCTTTCA TTGTGTATGT ACCAGCTATA 
GCTCTGAATC AGGTATCGGG CATTAATCTC CATGTGATTG CAGTGGTAAT TGTGGTCGTG 
TGTGTTTTCT ACACCTTTGT CGGAGGAATC AAAGCAGTGG TCCACACAGA TGCTTGGCAG 
GTGCTGGTCA TGTTCCTTTC CGTTCTTGCT GTGGCTATTT TGGCCACTGT CTATGCAAAT 
GGCTTGAATG TCCTTTTCGA TGATGCTGCC AAAGGTGGCC GATTGATCTT TAACAATACA 
AACCCATCGC CTTATGTAAG GCACACTGTT TGGAGCGTCC TAATCGGGGG ATTCTCCTAC 
TGGACCTCAT TCAATGCCGT CAACCAGACC ATGGTCCAGC GATACATGTC TCTTCCATCG 
CTCAAGAAGG CTCGTGCTTC CATGGCCATT TTTACAATTG GCGTGGCTGC CTTCGTCTCT 
GTTTGTTGTT ATGTGGGACT GCTAATCTAT GAGATGTACA AAGATTGTGA TCCTCTGAGT 
GCGGGACTAA TAACACACGA CGATCAGCTA CTGCCGCTCT TTGTCGTTCA GAGTGTGGGT 
CATATCTATG GTATGTCTGG TTTGTTTATA GCCGGCATAT TTGGAGCTGC CTTGAGCTCC 
CTTTCTGTGG TTCTGAACTC AACGTCCTTG GTAATCCTGG AGGATATAGT TCGCGGCTGC 
TTCAAGATGC AACCAAGTGA AAGAGCCTCC ACCATTCTGG TAAAGTCAAC TGTTATAGTT 
CTTGGCTTTG TGGCCCTATC ACTGGTATTT GTCCTGGAAC AACTGAGTGG AATCCTGAGC 
ATTTGCACTT CAATGACGGC CATCGCAGCT GGAACCACTT TTGGCCTGTT TACCCTGGGA 
ATGCTCGTTC CCTGGGCCAA TACTGTAGGC ACTGCTGTGG GCGGAATTGC AAGTGCTCTG 
CTCGCCGGGT GGATATCCTT TGGAACGCAG TTTACCATCG CAGCGGGTGA ATTGAATTCT 
CAAAAGCTTC CCGTATCCGT GGAGGGATGT GTGGGCAATG TAACGCTTCG GGAAAATATA 
TGGGTAGATG AGGAGCAAGT TTTTCCACTG TACCGACTGT CCTACCACTG GATAAATCCC 
ATTGGTGTGG CCACAGTCAT TGTGGTAGGT GCACTAGTCT CCCTTGTGAC CAAACCCACA 
AATATGAAAA CACTAGATCC GGATCTAATA TCACCAGTGA TTCACAGATT CCTTCCAAAA 
GAATGCTTTA GTGGTCGCAA TCTCCATGCG CAGGCGCACA AAAACCTCTT AAACGTATCC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_609192.1
CDS	438..2240
Translation	MEAVAKKGMENYRFGSVDYAVFLGMIVLSTSTGIYFGCIKKSKVKLEEAEPTLPTTTPKRRKHDFGSEKMSEYLLGSRNLKVFPVAMSLIASYISGVTILGTTSEIYNYGTQYWFIAIAIMLQGIAVSYVYIPVFSALQVGSSYEYLEMRFHSVVRSIASFMFILDEILFLPFIVYVPAIALNQVSGINLHVIAVVIVVVCVFYTFVGGIKAVVHTDAWQVLVMFLSVLAVAILATVYANGLNVLFDDAAKGGRLIFNNTNPSPYVRHTVWSVLIGGFSYWTSFNAVNQTMVQRYMSLPSLKKARASMAIFTIGVAAFVSVCCYVGLLIYEMYKDCDPLSAGLITHDDQLLPLFVVQSVGHIYGMSGLFIAGIFGAALSSLSVVLNSTSLVILEDIVRGCFKMQPSERASTILVKSTVIVLGFVALSLVFVLEQLSGILSICTSMTAIAAGTTFGLFTLGMLVPWANTVGTAVGGIASALLAGWISFGTQFTIAAGELNSQKLPVSVEGCVGNVTLRENIWVDEEQVFPLYRLSYHWINPIGVATVIVVGALVSLVTKPTNMKTLDPDLISPVIHRFLPKECFSGRNLHAQAHKNLLNVS

Target ORF information:

RefSeq Version	NM_135348.3
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster Sodium/solute co-transporter-like 5A11 (SLC5A11), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_135348.3

ORF Insert Sequence:

ATGGAAGCGG TGGCAAAGAA GGGCATGGAG AACTACAGAT TTGGCAGTGT GGACTATGCC 
GTTTTCCTGG GCATGATCGT ATTATCCACC AGCACGGGCA TCTATTTCGG GTGCATCAAG 
AAGAGCAAGG TGAAGCTCGA GGAGGCGGAA CCCACTCTGC CGACGACCAC GCCAAAAAGG 
CGGAAACACG ATTTCGGATC GGAGAAGATG AGCGAGTATC TGCTAGGGTC ACGCAATCTG 
AAAGTTTTCC CCGTTGCCAT GAGCCTGATA GCCAGCTATA TATCGGGCGT TACCATACTG 
GGCACAACCT CTGAGATCTA CAATTATGGC ACGCAATATT GGTTTATAGC CATAGCAATA 
ATGCTCCAAG GTATTGCCGT CTCCTACGTC TACATACCAG TGTTCTCGGC TCTTCAAGTA 
GGCTCTTCCT ATGAGTACTT GGAGATGCGC TTTCATTCGG TCGTACGAAG TATTGCATCC 
TTTATGTTTA TTCTGGATGA GATTCTGTTT CTGCCTTTCA TTGTGTATGT ACCAGCTATA 
GCTCTGAATC AGGTATCGGG CATTAATCTC CATGTGATTG CAGTGGTAAT TGTGGTCGTG 
TGTGTTTTCT ACACCTTTGT CGGAGGAATC AAAGCAGTGG TCCACACAGA TGCTTGGCAG 
GTGCTGGTCA TGTTCCTTTC CGTTCTTGCT GTGGCTATTT TGGCCACTGT CTATGCAAAT 
GGCTTGAATG TCCTTTTCGA TGATGCTGCC AAAGGTGGCC GATTGATCTT TAACAATACA 
AACCCATCGC CTTATGTAAG GCACACTGTT TGGAGCGTCC TAATCGGGGG ATTCTCCTAC 
TGGACCTCAT TCAATGCCGT CAACCAGACC ATGGTCCAGC GATACATGTC TCTTCCATCG 
CTCAAGAAGG CTCGTGCTTC CATGGCCATT TTTACAATTG GCGTGGCTGC CTTCGTCTCT 
GTTTGTTGTT ATGTGGGACT GCTAATCTAT GAGATGTACA AAGATTGTGA TCCTCTGAGT 
GCGGGACTAA TAACACACGA CGATCAGCTA CTGCCGCTCT TTGTCGTTCA GAGTGTGGGT 
CATATCTATG GTATGTCTGG TTTGTTTATA GCCGGCATAT TTGGAGCTGC CTTGAGCTCC 
CTTTCTGTGG TTCTGAACTC AACGTCCTTG GTAATCCTGG AGGATATAGT TCGCGGCTGC 
TTCAAGATGC AACCAAGTGA AAGAGCCTCC ACCATTCTGG TAAAGTCAAC TGTTATAGTT 
CTTGGCTTTG TGGCCCTATC ACTGGTATTT GTCCTGGAAC AACTGAGTGG AATCCTGAGC 
ATTTGCACTT CAATGACGGC CATCGCAGCT GGAACCACTT TTGGCCTGTT TACCCTGGGA 
ATGCTCGTTC CCTGGGCCAA TACTGTAGGC ACTGCTGTGG GCGGAATTGC AAGTGCTCTG 
CTCGCCGGGT GGATATCCTT TGGAACGCAG TTTACCATCG CAGCGGGTGA ATTGAATTCT 
CAAAAGCTTC CCGTATCCGT GGAGGGATGT GTGGGCAATG TAACGCTTCG GGAAAATATA 
TGGGTAGATG AGGAGCAAGT TTTTCCACTG TACCGACTGT CCTACCACTG GATAAATCCC 
ATTGGTGTGG CCACAGTCAT TGTGGTAGGT GCACTAGTCT CCCTTGTGAC CAAACCCACA 
AATATGAAAA CACTAGATCC GGATCTAATA TCACCAGTGA TTCACAGATT CCTTCCAAAA 
GAATGCTTTA GTGGTCGCAA TCTCCATGCG CAGGCGCACA AAAACCTCTT AAACGTATCC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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SLC5A11 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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