morgue cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	morgue
Entrez Gene ID	33648
Full Name	modifier of rpr and grim, ubiquitously expressed
Synonyms	BcDNA:GH02435,CG15437,Dmel\CG15437,FBXO18,Morgue
General protein information	Preferred Names modifier of rpr and grim, ubiquitously expressed Names CG15437 gene product from transcript CG15437-RA CG15437-PA morgue-PA
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 2L Map Location: 24F2-24F2

mRNA and Protein(s)

mRNA	Protein	Name
NM_134989.3	NP_608833.1	modifier of rpr and grim, ubiquitously expressed

Pathways from BioSystems

Homologies

Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008941	XP_319696.4
Drosophila melanogaster (fruit fly)	morgue	NP_608833.1

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Drosophila morgue associates with SkpA and polyubiquitin in vivo.
Title: Drosophila morgue associates with SkpA and polyubiquitin in vivo.

study of normal developmental and physiological functions of morgue; study revealed Morgue localization in multiple cellular compartments; taken together, the diverse phenotypes observed and distribution patterns suggest pleiotropic functions for Morgue
Title: Drosophila morgue influences cell numbers and positions in the embryonic nervous system.

Drosophila morgue has a role in protein ubiquitination and programmed cell death
Title: Drosophila morgue and the intersection between protein ubiquitination and programmed cell death.

Drosophila Morgue is an F box/ubiquitin conjugase domain protein important for grim-reaper mediated apoptosis.
Title: Drosophila Morgue is an F box/ubiquitin conjugase domain protein important for grim-reaper mediated apoptosis.

Morgue mediates apoptosis in the Drosophila melanogaster retina by promoting degradation of DIAP1.
Title: Morgue mediates apoptosis in the Drosophila melanogaster retina by promoting degradation of DIAP1.

The following morgue gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the morgue cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OFa13730	NM_134989.3 Latest version!	Drosophila melanogaster modifier of rpr and grim, ubiquitously expressed (morgue), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

morgue ( NM_134989.3 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_608833.1 Drosophila melanogaster modifier of rpr and grim, ubiquitously expressed (morgue), mRNA.

Price & Availability↑

CloneID	OFa13730
Clone ID Related Accession (Same CDS sequence)	NM_134989.3
Accession Version	NM_134989.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1476bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	modifier of rpr and grim, ubiquitously expressed
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033779). On Jan 16, 2013 this sequence version replaced NM_134989.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGACTAGCT GCGTGCCAGC GCATCAGCAA AAGGACCAGG AGCAGTTGCT AAAGGAACTG 
GCCAGCAGTG GCGACGAGAT GGACGACCCG GACGATCCGG ACCAGGAACA CCACCAGCTG 
GTAGAGCCGA CCTTCTCTTT TTCGAATAGT AACACCTGCT GGGTGTGCAA CGGCTACTAT 
GGGCCCAACT TCGGGGAGCC GTTGTGCGGC GCCTGCCACG CCTTCCTGTA CAACGCACAG 
CGGGCGGAGG AGCTGCTCAC GGAGCTTTCC GATGACGAGG ATTCTGGGAA CGACGAGCCG 
CCGTTCAAGG ACAAGCAGGA AGACGAGGAG ACCGAAAACG ACGTAGACAT CATGGGCTTT 
GAGGATCTGG AGGACCCCCA ACCGGCAGCC GTGCCACAAC ATCCAAATCC GCAGCCACCA 
ATGGAGCCAC AGGATCAACA GCCAGCCCAA CCAGTTATAG ATCTGCCACA GCCGGTGCCG 
GAGGCTGCGG CACCACGACG CGAGTCTCCG GAGCGCGACT TTGAGCACGA GAGAGCCATT 
AATCCCTTCC TGCTGCCCAT TAAGCGTCCG CGGGCCACGG CTCCCTTGGC TCTGCCCCAT 
TACATGCATG AGCTGGCCGA TGGAAGGGCG CGAGTGCATG AATACAACGC CGCCAGCGGA 
AGCGGAGCAA GTGGCAGCAG CAGAAACATT GTCAACATAA TACCCGTCGA GGTGATGCTG 
AAAATATTTG CCTATTTGGA CGACATGTCG CTGTGGATGG CTAGTGAAGT TTGCAAGCAA 
TGGCACGACA TTGTCGGGAA AAACACGGCC CAGAGCATGT GGAAGGCGTA TATCAAGCAG 
CGCTGGCCGC TGTTCGACAG TTTGGCAGAC AATCCAAACT GGTATCGGCT GTACGGGGCA 
CTGATGTCTT CCTGCTTCTG TCGCACTTGC CTGATTGAGA TGGGCGGTCG GGGTCAGGAT 
GCACAGGAGG CAGATCCACA GCTGGGCGAT CGGGAGCCGG GCAATGTAAT GCGCAACAAC 
TTTCTGCGCG GTGAAGCCAA TCTGCTGAAC AGCTACGAAT CTGAGGGCAT ATCGGCCATA 
CCGTTGGATC GGCAAAACAA CTACTGGCAG GCGACAATTC TGGGGCCACC GGGCAGTCCC 
TACGAAGGCG GCAAGTTCTT CCTGTTCATA TACTTCCCGG AGCGATATCC GATGACGCCG 
CCCACAGTAC GTTTCCTCAC CAAAATCCTG CATCCGAATG TTTCGCGGCA TGGGGACGTG 
GGCATCGACA TCTTCCAGCA GCACAACTGG TCTCTGGCGC TGAACGTGGC CAAGGTGCTG 
CTTTCTGTGC AGAGCCTGCT GACCGATCCG TATACCGAAG TCTGCATGGA GCCTGAACTT 
GGATACATCT ATGAGCACGA GCGCGAAAGG TTCGAGCAAC TGGTGCGCGC GTGGACATGG 
AAGTACGCCA TGTACGAGCT AATTGCACCG CGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_608833.1
CDS	74..1549
Translation	MTSCVPAHQQKDQEQLLKELASSGDEMDDPDDPDQEHHQLVEPTFSFSNSNTCWVCNGYYGPNFGEPLCGACHAFLYNAQRAEELLTELSDDEDSGNDEPPFKDKQEDEETENDVDIMGFEDLEDPQPAAVPQHPNPQPPMEPQDQQPAQPVIDLPQPVPEAAAPRRESPERDFEHERAINPFLLPIKRPRATAPLALPHYMHELADGRARVHEYNAASGSGASGSSRNIVNIIPVEVMLKIFAYLDDMSLWMASEVCKQWHDIVGKNTAQSMWKAYIKQRWPLFDSLADNPNWYRLYGALMSSCFCRTCLIEMGGRGQDAQEADPQLGDREPGNVMRNNFLRGEANLLNSYESEGISAIPLDRQNNYWQATILGPPGSPYEGGKFFLFIYFPERYPMTPPTVRFLTKILHPNVSRHGDVGIDIFQQHNWSLALNVAKVLLSVQSLLTDPYTEVCMEPELGYIYEHERERFEQLVRAWTWKYAMYELIAPR

Target ORF information:

RefSeq Version	NM_134989.3
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster modifier of rpr and grim, ubiquitously expressed (morgue), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_134989.3

ORF Insert Sequence:

ATGACTAGCT GCGTGCCAGC GCATCAGCAA AAGGACCAGG AGCAGTTGCT AAAGGAACTG 
GCCAGCAGTG GCGACGAGAT GGACGACCCG GACGATCCGG ACCAGGAACA CCACCAGCTG 
GTAGAGCCGA CCTTCTCTTT TTCGAATAGT AACACCTGCT GGGTGTGCAA CGGCTACTAT 
GGGCCCAACT TCGGGGAGCC GTTGTGCGGC GCCTGCCACG CCTTCCTGTA CAACGCACAG 
CGGGCGGAGG AGCTGCTCAC GGAGCTTTCC GATGACGAGG ATTCTGGGAA CGACGAGCCG 
CCGTTCAAGG ACAAGCAGGA AGACGAGGAG ACCGAAAACG ACGTAGACAT CATGGGCTTT 
GAGGATCTGG AGGACCCCCA ACCGGCAGCC GTGCCACAAC ATCCAAATCC GCAGCCACCA 
ATGGAGCCAC AGGATCAACA GCCAGCCCAA CCAGTTATAG ATCTGCCACA GCCGGTGCCG 
GAGGCTGCGG CACCACGACG CGAGTCTCCG GAGCGCGACT TTGAGCACGA GAGAGCCATT 
AATCCCTTCC TGCTGCCCAT TAAGCGTCCG CGGGCCACGG CTCCCTTGGC TCTGCCCCAT 
TACATGCATG AGCTGGCCGA TGGAAGGGCG CGAGTGCATG AATACAACGC CGCCAGCGGA 
AGCGGAGCAA GTGGCAGCAG CAGAAACATT GTCAACATAA TACCCGTCGA GGTGATGCTG 
AAAATATTTG CCTATTTGGA CGACATGTCG CTGTGGATGG CTAGTGAAGT TTGCAAGCAA 
TGGCACGACA TTGTCGGGAA AAACACGGCC CAGAGCATGT GGAAGGCGTA TATCAAGCAG 
CGCTGGCCGC TGTTCGACAG TTTGGCAGAC AATCCAAACT GGTATCGGCT GTACGGGGCA 
CTGATGTCTT CCTGCTTCTG TCGCACTTGC CTGATTGAGA TGGGCGGTCG GGGTCAGGAT 
GCACAGGAGG CAGATCCACA GCTGGGCGAT CGGGAGCCGG GCAATGTAAT GCGCAACAAC 
TTTCTGCGCG GTGAAGCCAA TCTGCTGAAC AGCTACGAAT CTGAGGGCAT ATCGGCCATA 
CCGTTGGATC GGCAAAACAA CTACTGGCAG GCGACAATTC TGGGGCCACC GGGCAGTCCC 
TACGAAGGCG GCAAGTTCTT CCTGTTCATA TACTTCCCGG AGCGATATCC GATGACGCCG 
CCCACAGTAC GTTTCCTCAC CAAAATCCTG CATCCGAATG TTTCGCGGCA TGGGGACGTG 
GGCATCGACA TCTTCCAGCA GCACAACTGG TCTCTGGCGC TGAACGTGGC CAAGGTGCTG 
CTTTCTGTGC AGAGCCTGCT GACCGATCCG TATACCGAAG TCTGCATGGA GCCTGAACTT 
GGATACATCT ATGAGCACGA GCGCGAAAGG TTCGAGCAAC TGGTGCGCGC GTGGACATGG 
AAGTACGCCA TGTACGAGCT AATTGCACCG CGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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morgue cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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