slp1 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	slp1
Entrez Gene ID	33607
Full Name	sloppy paired 1
Synonyms	CG16738,Dmel\CG16738,Dmslp1,FD6,FoxG,SLP,SLP1,Slp,Slp-1,Slp1,l(2)05965,sko1,slp,slp-1,slp-2
General protein information	Preferred Names sloppy paired 1 Names CG16738 gene product from transcript CG16738-RA CG16738-PA Sloppy-paired Sloppy-paired1 sloppy sloppy pair sloppy paired sloppy-paired 1 sloppy-paired-1 slp1-PA
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 2L Map Location: 24C6-24C6\|2-8 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_057382.3	NP_476730.1	sloppy paired 1

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

slp1 and slp2 are coordinately regulated by 8 stripe enhancers surrounding slp1.
Title: Regulation of a duplicated locus: Drosophila sloppy paired is replete with functionally overlapping enhancers.

Taken together, these data show that Slp1/Foxg1 regulate glial cell fates by inhibiting Gcm function
Title: Sloppy paired 1/2 regulate glial cell fates by inhibiting Gcm function.

Results suggest that sloppy-paired 1 functions as a gap gene-like repressor, and contains a protein motif which mediates binding to the transcriptional corepressor Groucho.
Title: Groucho-dependent repression by sloppy-paired 1 differentially positions anterior pair-rule stripes in the Drosophila embryo.

abdominal Hox proteins work directly with two segmentation proteins, Sloppy paired and Engrailed, to repress the Hox target gene Distalless in anterior and posterior compartments, respectively; segmentation proteins can function as Hox cofactors
Title: Direct integration of Hox and segmentation gene inputs during Drosophila development.

The following slp1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the slp1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OFa13686	NM_057382.3 Latest version!	Drosophila melanogaster sloppy paired 1 (slp1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

slp1 ( NM_057382.3 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_476730.1 Drosophila melanogaster sloppy paired 1 (slp1), mRNA.

Price & Availability↑

CloneID	OFa13686
Clone ID Related Accession (Same CDS sequence)	NM_057382.3
Accession Version	NM_057382.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 969bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	sloppy paired 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033779). On Jan 16, 2013 this sequence version replaced NM_057382.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGTGAAAA GTGAAATGGA ATTCAAGAGC AACTTCTCCA TCGATGCCAT CTTGGCCAAG 
AAACCCATCA ACACCGCAAC TCAACCCATC AAAACCGAAC CGGTGCATCA TCATCATCAG 
TACGTTCATC CGTACTCCAA TTCCGATGGC GAACTCTCGG CTTCGGAGGA TTTCGACAGC 
CCCAGCAGGA CCAGCACACC CATGAGCAGT GCCGCCGAGA GTCTATCGTC GCAAAACAAT 
GACAAGCTCG ACGTGGAGTT CGACGATGAG CTGGAGGATC AGCTGGACGA GGACCAGGAG 
AGCGAGGATG GCAATCCCAG CAAGAAACAG AAAATGACCG CCGGCAGCGA TACCAAGAAA 
CCGCCATACA GCTACAACGC CCTCATCATG ATGGCCATCC AGGATAGTCC CGAGCAGCGG 
TTGACTTTGA ATGGCATCTA TCAGTATCTG ATCAATAGAT TCCCCTACTT CAAGGCCAAC 
AAGCGGGGCT GGCAGAACTC CATTCGCCAC AATCTGAGCC TGAACAAGTG CTTCACGAAG 
ATTCCCCGCA GCTACGATGA TCCCGGCAAG GGCAACTACT GGATCCTGGA CCCCTCGGCC 
GAGGAGGTAT TCATTGGCGA GACCACCGGC AAGCTGAGGC GCAAGAATCC CGGCGCCAGT 
CGCACTCGCC TGGCCGCCTA TCGTCAGGCC ATATTCTCGC CGATGATGGC TGCTTCACCA 
TACGGAGCTC CAGCTTCCAG CTACGGATAC CCGGCTGTTC CATTCGCCGC CGCTGCCGCC 
GCCGCCCTGT ACCAGCGCAT GAATCCCGCT GCCTATCAGG CTGCCTATCA GCAGATGCAG 
TACCAGCAGG CTCCTCAGGC CCACCATCAT CAGGCGCCCC ATCCCGCCCA GATGCAGGGC 
TATCCACAAC AATTGAACGC CGAGTTGTTT CAGCGCATGC AGTTCTTTGG CAAGTTTCCA 
TCCAGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_476730.1
CDS	110..1078
Translation	MVKSEMEFKSNFSIDAILAKKPINTATQPIKTEPVHHHHQYVHPYSNSDGELSASEDFDSPSRTSTPMSSAAESLSSQNNDKLDVEFDDELEDQLDEDQESEDGNPSKKQKMTAGSDTKKPPYSYNALIMMAIQDSPEQRLTLNGIYQYLINRFPYFKANKRGWQNSIRHNLSLNKCFTKIPRSYDDPGKGNYWILDPSAEEVFIGETTGKLRRKNPGASRTRLAAYRQAIFSPMMAASPYGAPASSYGYPAVPFAAAAAAALYQRMNPAAYQAAYQQMQYQQAPQAHHHQAPHPAQMQGYPQQLNAELFQRMQFFGKFPSS

Target ORF information:

RefSeq Version	NM_057382.3
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster sloppy paired 1 (slp1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_057382.3

ORF Insert Sequence:

ATGGTGAAAA GTGAAATGGA ATTCAAGAGC AACTTCTCCA TCGATGCCAT CTTGGCCAAG 
AAACCCATCA ACACCGCAAC TCAACCCATC AAAACCGAAC CGGTGCATCA TCATCATCAG 
TACGTTCATC CGTACTCCAA TTCCGATGGC GAACTCTCGG CTTCGGAGGA TTTCGACAGC 
CCCAGCAGGA CCAGCACACC CATGAGCAGT GCCGCCGAGA GTCTATCGTC GCAAAACAAT 
GACAAGCTCG ACGTGGAGTT CGACGATGAG CTGGAGGATC AGCTGGACGA GGACCAGGAG 
AGCGAGGATG GCAATCCCAG CAAGAAACAG AAAATGACCG CCGGCAGCGA TACCAAGAAA 
CCGCCATACA GCTACAACGC CCTCATCATG ATGGCCATCC AGGATAGTCC CGAGCAGCGG 
TTGACTTTGA ATGGCATCTA TCAGTATCTG ATCAATAGAT TCCCCTACTT CAAGGCCAAC 
AAGCGGGGCT GGCAGAACTC CATTCGCCAC AATCTGAGCC TGAACAAGTG CTTCACGAAG 
ATTCCCCGCA GCTACGATGA TCCCGGCAAG GGCAACTACT GGATCCTGGA CCCCTCGGCC 
GAGGAGGTAT TCATTGGCGA GACCACCGGC AAGCTGAGGC GCAAGAATCC CGGCGCCAGT 
CGCACTCGCC TGGCCGCCTA TCGTCAGGCC ATATTCTCGC CGATGATGGC TGCTTCACCA 
TACGGAGCTC CAGCTTCCAG CTACGGATAC CCGGCTGTTC CATTCGCCGC CGCTGCCGCC 
GCCGCCCTGT ACCAGCGCAT GAATCCCGCT GCCTATCAGG CTGCCTATCA GCAGATGCAG 
TACCAGCAGG CTCCTCAGGC CCACCATCAT CAGGCGCCCC ATCCCGCCCA GATGCAGGGC 
TATCCACAAC AATTGAACGC CGAGTTGTTT CAGCGCATGC AGTTCTTTGG CAAGTTTCCA 
TCCAGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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slp1 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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