Drp1 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	Drp1
Entrez Gene ID	33445
Full Name	Dynamin related protein 1
Synonyms	CG3210,DRP,DRP1,Dmel\CG3210,Dnm1/Drp1,Drp,Drp-1,drp-1,drp1,frat,l(2)22Fc,l(2)22Fd,l(2)ND2,l(2)ND3
General protein information	Preferred Names Dynamin related protein 1 Names CG3210 gene product from transcript CG3210-RB CG3210-PA CG3210-PB Drp1-PA Drp1-PB dynamin related protein 1 dynamin related protein-1 dynamin-2 dynamin-related protein dynamin-related protein 1 dynaminrelated protein 1 fratboy lethal(2)22Fc lethal(2)22Fd near dpp complementation group 2 near dpp complementation group 3 noodle
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 2L Map Location: 23A1-23A1

mRNA and Protein(s)

mRNA	Protein	Name
NM_134850.3	NP_608694.2	dynamin related protein 1, isoform A
NM_001273017.1	NP_001259946.1	dynamin related protein 1, isoform B

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	DNM1L	NP_001073190.1
Drosophila melanogaster (fruit fly)	Drp1	NP_001259946.1
Eremothecium gossypii	AGOS_AAL174C	NP_982368.1
Magnaporthe oryzae (rice blast fungus)	MGG_06361	XP_003717217.1
Saccharomyces cerevisiae (baker's yeast)	DNM1	NP_013100.1
Neurospora crassa	NCU09808	XP_964068.1
Homo sapiens (human)	DNM1L	NP_001265393.1
Canis lupus familiaris (dog)	DNM1L	XP_005637046.1
Oryza sativa (rice)	Os04g0381000	NP_001052600.1
	DNM1L	XP_002798572.1
Bos taurus (cattle)	DNM1L	NP_001039959.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008896	XP_319643.4
Pan troglodytes (chimpanzee)	DNM1L	XP_520720.3
Mus musculus (house mouse)	Dnm1l	NP_001263269.1
Rattus norvegicus (Norway rat)	Dnm1l	NP_446107.2
Danio rerio (zebrafish)	dnm1l	NP_957216.1
Caenorhabditis elegans (roundworm)	drp-1	NP_741403.2
Kluyveromyces lactis	KLLA0F12892g	XP_455660.1
Schizosaccharomyces pombe (fission yeast)	dnm1	NP_596014.1
Xenopus tropicalis (tropical clawed frog)	dnm1l	XP_004912361.1

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data show that short-term induction of Drp1, in midlife, is sufficient to improve organismal health and prolong lifespan.
Title: Promoting Drp1-mediated mitochondrial fission in midlife prolongs healthy lifespan of Drosophila melanogaster.

Study showed that exogenous expression of Drp1 could promote crawling ability, reduced the level of ATP in Drosophila brain and suppressed neuronal degeneration, suggesting that Drp1 is involved in the pathogenesis of Alzheimer disease.
Title: Exogenous expression of Drp1 plays neuroprotective roles in the Alzheimer's disease in the A?42 transgenic Drosophila model.

Results show that centronuclear myopathy associated Dyn2 mutants are gain-of-function mutations, and their primary effect in muscle is T-tubule disorganization, which explains the susceptibility of muscle to Dyn2 hyperactivity.
Title: Dynamin-2 mutations associated with centronuclear myopathy are hypermorphic and lead to T-tubule fragmentation.

Debcl modulates Drp1 mitochondrial localization during apoptosis.
Title: The Drosophila retinoblastoma protein, Rbf1, induces a Debcl- and Drp1-dependent mitochondrial apoptosis.

Thus, DRP1-dependent mitochondrial fission activity is a novel regulator of the onset of follicle cell differentiation during Drosophila
Title: DRP1-dependent mitochondrial fission initiates follicle cell differentiation during Drosophila oogenesis.

The following Drp1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Drp1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OFa13517	NM_134850.3 Latest version!	Drosophila melanogaster dynamin related protein 1, transcript variant A (Drp1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$426.30 $609.00
OFa13517	NM_001273017.1 Latest version!	Drosophila melanogaster dynamin related protein 1, transcript variant B (Drp1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$426.30 $609.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Drp1 ( NM_134850.3 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_608694.2 Drosophila melanogaster dynamin related protein 1, transcript variant A (Drp1), mRNA.

Price & Availability↑

CloneID	OFa13517
Clone ID Related Accession (Same CDS sequence)	NM_134850.3 , NM_001273017.1
Accession Version	NM_134850.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2208bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	dynamin related protein 1, isoform A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033779). On Jan 16, 2013 this sequence version replaced NM_134850.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGAGGCCC TAATTCCGGT CATAAACAAG CTGCAGGACG TCTTCAACAC CGTGGGCTCC 
GACTCCATCC AATTGCCCCA AATTGTTGTT CTAGGCAGTC AGAGCTCCGG CAAGAGTTCG 
GTGATCGAGA GCGTTGTGGG ACGATCCTTT CTGCCCCGTG GAACTGGTAT TGTGACCCGT 
CGCCCACTGG TGCTCCAGCT GATCTACAGC CCACTCGATG ATCGCGAGAA TCGCTCGGCG 
GAAAATGGTA CGTCCAATGC CGAGGAGTGG GGCCGCTTCC TGCACACCAA GAAGTGCTTC 
ACGGACTTTG ACGAGATCCG CAAGGAGATC GAAAACGAAA CGGAGCGGGC GGCGGGCAGC 
AACAAGGGCA TCTGCCCGGA GCCCATCAAC CTGAAGATAT TCTCAACGCA CGTGGTCAAC 
CTAACGCTGG TGGATCTGCC CGGCATCACC AAGGTCCCGG TGGGCGATCA GCCGGAGGAT 
ATCGAGGCGC AGATCAAAGA ATTGGTCCTC AAGTACATTG AGAACCCGAA CTCCATCATT 
TTGGCTGTGA CGGCCGCCAA CACGGACATG GCCACCAGTG AGGCACTCAA GCTGGCCAAG 
GACGTGGACC CCGATGGCCG GCGCACTCTG GCCGTGGTCA CGAAACTGGA TCTCATGGAT 
GCCGGCACCG ATGCCATCGA CATCCTGTGC GGCCGGGTCA TTCCCGTCAA GCTGGGCATC 
ATCGGCGTTA TGAATCGCTC GCAGAAGGAC ATCATGGACC AAAAGCACAT CGACGATCAG 
ATGAAGGACG AGGCCGCCTT CCTGCAGCGC AAGTATCCCA CTCTGGCCAC CCGGAACGGC 
ACGCCCTACT TGGCCAAGAC CCTCAACCGG CTCCTGATGC ACCACATCCG GGACTGCCTG 
CCAGATCTTA AGACTCGCGT CAACATCATG GCCACGCAAT TCCAATCGCT GCTGAACTCC 
TATGGCGAGG ATGTCTCCGA CAAGAGCCAG ACCCTGCTGC AGATCATCAC GAAGTTCTCC 
AGCGCCTACT GCTGCACAAT CGAGGGCACG GCCAGGAATA TCGAGACCAC GGAACTGTGC 
GGCGGTGCCC GGATGGGCTA CATTTTCCAC GAGACCTTCG GCCGCACCCT GGACTCCATT 
CACCCGCTGG CGGGTCTGAG CAAGATGGAC ATACTGACAG CCATCCGGAA TGCCACTGGT 
CCACGCCCGG CTTTGTTCGT TCCGGAGGTC TCGTTCGAAC TGCTAGTGAA GCGCCAGATT 
CGCCGCCTGG AGGAACCCTC CTTGCGCTGC GTGGAACTCA TTCACGAGGA GATGCAGCGC 
ATTGTTCAGC ATTGTGGCAA CGAAGTGCAG CAGGAGATGC TGCGCTTTCC CAAACTGCAC 
GAGAAGATTG TGGACGTGGT CACCCAGCTG CTGCGTCGAC GTCTGCCGCA CACCAACGTG 
ATGGTGGAGA ACATTGTGGC CATCGAGCTG GCCTACATCA ACACCAAGCA CCCCGACTTC 
CACAAGGATG CCGCTTTGGT GCCCAGTCTG CTGAAAACGG ACAGCGATCC CTACTCACAG 
ATAAATCTGG GGCAGCGGCG GGCCAATACA CCGCGAAACC ACATGTCGCC TCAGATTTCG 
TCGCACAGTG CTGGTTCACA GCAGCCGCAG CAGCAACAGC CGCCGCAGCC GAATTCCTCA 
CAGCAGCAAT ATAGCCAAGT GCATGAGCAG AACCACGTCG CCGAGAACTC GACGCCTTCG 
ATGGCCAGCA CATGGCTGTC AAACATTTTA CCGCCGGCAC CAACGCGTCC GGACAGCATT 
GAGAACTCGA CCAACAACAC TCCGGTTCAC AATAACATCG TGAGTCCAGT GAAGCCGGTC 
AATCTGCTGC CCGATGTGCC GGCCAACCAC AATCCACGTC GCCTCACTGA CAAGGAGCAG 
AAGGATTGCG ATGTCATCGA ACACCTGATC AAATCGTATT TCTACATTGT GCGCAAATCC 
ATACAAGACT CGGTTCCAAA GGCCATCATG CATTTCTTGG TTAACTACGT TAAGGACAAC 
TTGCAGAGCG AATTGGTTAC ACATCTGTAT AAGTCGGATA AGGCTGAAAC CCTGCTCAAC 
GAGTCCGATC ACATTGCAGT GCGCCGAAAA GAGGCGGCAG ATATGCTGAA GGCACTGACG 
CGAGCGAATC ACATCATCAG CGAAATCCGC GAGACCCACA TGTGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_608694.2
CDS	160..2367
Translation	MEALIPVINKLQDVFNTVGSDSIQLPQIVVLGSQSSGKSSVIESVVGRSFLPRGTGIVTRRPLVLQLIYSPLDDRENRSAENGTSNAEEWGRFLHTKKCFTDFDEIRKEIENETERAAGSNKGICPEPINLKIFSTHVVNLTLVDLPGITKVPVGDQPEDIEAQIKELVLKYIENPNSIILAVTAANTDMATSEALKLAKDVDPDGRRTLAVVTKLDLMDAGTDAIDILCGRVIPVKLGIIGVMNRSQKDIMDQKHIDDQMKDEAAFLQRKYPTLATRNGTPYLAKTLNRLLMHHIRDCLPDLKTRVNIMATQFQSLLNSYGEDVSDKSQTLLQIITKFSSAYCCTIEGTARNIETTELCGGARMGYIFHETFGRTLDSIHPLAGLSKMDILTAIRNATGPRPALFVPEVSFELLVKRQIRRLEEPSLRCVELIHEEMQRIVQHCGNEVQQEMLRFPKLHEKIVDVVTQLLRRRLPHTNVMVENIVAIELAYINTKHPDFHKDAALVPSLLKTDSDPYSQINLGQRRANTPRNHMSPQISSHSAGSQQPQQQQPPQPNSSQQQYSQVHEQNHVAENSTPSMASTWLSNILPPAPTRPDSIENSTNNTPVHNNIVSPVKPVNLLPDVPANHNPRRLTDKEQKDCDVIEHLIKSYFYIVRKSIQDSVPKAIMHFLVNYVKDNLQSELVTHLYKSDKAETLLNESDHIAVRRKEAADMLKALTRANHIISEIRETHMW

Target ORF information:

RefSeq Version	NM_134850.3
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster dynamin related protein 1, transcript variant A (Drp1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_134850.3

ORF Insert Sequence:

ATGGAGGCCC TAATTCCGGT CATAAACAAG CTGCAGGACG TCTTCAACAC CGTGGGCTCC 
GACTCCATCC AATTGCCCCA AATTGTTGTT CTAGGCAGTC AGAGCTCCGG CAAGAGTTCG 
GTGATCGAGA GCGTTGTGGG ACGATCCTTT CTGCCCCGTG GAACTGGTAT TGTGACCCGT 
CGCCCACTGG TGCTCCAGCT GATCTACAGC CCACTCGATG ATCGCGAGAA TCGCTCGGCG 
GAAAATGGTA CGTCCAATGC CGAGGAGTGG GGCCGCTTCC TGCACACCAA GAAGTGCTTC 
ACGGACTTTG ACGAGATCCG CAAGGAGATC GAAAACGAAA CGGAGCGGGC GGCGGGCAGC 
AACAAGGGCA TCTGCCCGGA GCCCATCAAC CTGAAGATAT TCTCAACGCA CGTGGTCAAC 
CTAACGCTGG TGGATCTGCC CGGCATCACC AAGGTCCCGG TGGGCGATCA GCCGGAGGAT 
ATCGAGGCGC AGATCAAAGA ATTGGTCCTC AAGTACATTG AGAACCCGAA CTCCATCATT 
TTGGCTGTGA CGGCCGCCAA CACGGACATG GCCACCAGTG AGGCACTCAA GCTGGCCAAG 
GACGTGGACC CCGATGGCCG GCGCACTCTG GCCGTGGTCA CGAAACTGGA TCTCATGGAT 
GCCGGCACCG ATGCCATCGA CATCCTGTGC GGCCGGGTCA TTCCCGTCAA GCTGGGCATC 
ATCGGCGTTA TGAATCGCTC GCAGAAGGAC ATCATGGACC AAAAGCACAT CGACGATCAG 
ATGAAGGACG AGGCCGCCTT CCTGCAGCGC AAGTATCCCA CTCTGGCCAC CCGGAACGGC 
ACGCCCTACT TGGCCAAGAC CCTCAACCGG CTCCTGATGC ACCACATCCG GGACTGCCTG 
CCAGATCTTA AGACTCGCGT CAACATCATG GCCACGCAAT TCCAATCGCT GCTGAACTCC 
TATGGCGAGG ATGTCTCCGA CAAGAGCCAG ACCCTGCTGC AGATCATCAC GAAGTTCTCC 
AGCGCCTACT GCTGCACAAT CGAGGGCACG GCCAGGAATA TCGAGACCAC GGAACTGTGC 
GGCGGTGCCC GGATGGGCTA CATTTTCCAC GAGACCTTCG GCCGCACCCT GGACTCCATT 
CACCCGCTGG CGGGTCTGAG CAAGATGGAC ATACTGACAG CCATCCGGAA TGCCACTGGT 
CCACGCCCGG CTTTGTTCGT TCCGGAGGTC TCGTTCGAAC TGCTAGTGAA GCGCCAGATT 
CGCCGCCTGG AGGAACCCTC CTTGCGCTGC GTGGAACTCA TTCACGAGGA GATGCAGCGC 
ATTGTTCAGC ATTGTGGCAA CGAAGTGCAG CAGGAGATGC TGCGCTTTCC CAAACTGCAC 
GAGAAGATTG TGGACGTGGT CACCCAGCTG CTGCGTCGAC GTCTGCCGCA CACCAACGTG 
ATGGTGGAGA ACATTGTGGC CATCGAGCTG GCCTACATCA ACACCAAGCA CCCCGACTTC 
CACAAGGATG CCGCTTTGGT GCCCAGTCTG CTGAAAACGG ACAGCGATCC CTACTCACAG 
ATAAATCTGG GGCAGCGGCG GGCCAATACA CCGCGAAACC ACATGTCGCC TCAGATTTCG 
TCGCACAGTG CTGGTTCACA GCAGCCGCAG CAGCAACAGC CGCCGCAGCC GAATTCCTCA 
CAGCAGCAAT ATAGCCAAGT GCATGAGCAG AACCACGTCG CCGAGAACTC GACGCCTTCG 
ATGGCCAGCA CATGGCTGTC AAACATTTTA CCGCCGGCAC CAACGCGTCC GGACAGCATT 
GAGAACTCGA CCAACAACAC TCCGGTTCAC AATAACATCG TGAGTCCAGT GAAGCCGGTC 
AATCTGCTGC CCGATGTGCC GGCCAACCAC AATCCACGTC GCCTCACTGA CAAGGAGCAG 
AAGGATTGCG ATGTCATCGA ACACCTGATC AAATCGTATT TCTACATTGT GCGCAAATCC 
ATACAAGACT CGGTTCCAAA GGCCATCATG CATTTCTTGG TTAACTACGT TAAGGACAAC 
TTGCAGAGCG AATTGGTTAC ACATCTGTAT AAGTCGGATA AGGCTGAAAC CCTGCTCAAC 
GAGTCCGATC ACATTGCAGT GCGCCGAAAA GAGGCGGCAG ATATGCTGAA GGCACTGACG 
CGAGCGAATC ACATCATCAG CGAAATCCGC GAGACCCACA TGTGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Drp1 ( NM_001273017.1 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_001259946.1 Drosophila melanogaster dynamin related protein 1, transcript variant B (Drp1), mRNA.

Price & Availability↑

CloneID	OFa13517
Clone ID Related Accession (Same CDS sequence)	NM_134850.3 , NM_001273017.1
Accession Version	NM_001273017.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2208bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	dynamin related protein 1, isoform B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033779). ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGAGGCCC TAATTCCGGT CATAAACAAG CTGCAGGACG TCTTCAACAC CGTGGGCTCC 
GACTCCATCC AATTGCCCCA AATTGTTGTT CTAGGCAGTC AGAGCTCCGG CAAGAGTTCG 
GTGATCGAGA GCGTTGTGGG ACGATCCTTT CTGCCCCGTG GAACTGGTAT TGTGACCCGT 
CGCCCACTGG TGCTCCAGCT GATCTACAGC CCACTCGATG ATCGCGAGAA TCGCTCGGCG 
GAAAATGGTA CGTCCAATGC CGAGGAGTGG GGCCGCTTCC TGCACACCAA GAAGTGCTTC 
ACGGACTTTG ACGAGATCCG CAAGGAGATC GAAAACGAAA CGGAGCGGGC GGCGGGCAGC 
AACAAGGGCA TCTGCCCGGA GCCCATCAAC CTGAAGATAT TCTCAACGCA CGTGGTCAAC 
CTAACGCTGG TGGATCTGCC CGGCATCACC AAGGTCCCGG TGGGCGATCA GCCGGAGGAT 
ATCGAGGCGC AGATCAAAGA ATTGGTCCTC AAGTACATTG AGAACCCGAA CTCCATCATT 
TTGGCTGTGA CGGCCGCCAA CACGGACATG GCCACCAGTG AGGCACTCAA GCTGGCCAAG 
GACGTGGACC CCGATGGCCG GCGCACTCTG GCCGTGGTCA CGAAACTGGA TCTCATGGAT 
GCCGGCACCG ATGCCATCGA CATCCTGTGC GGCCGGGTCA TTCCCGTCAA GCTGGGCATC 
ATCGGCGTTA TGAATCGCTC GCAGAAGGAC ATCATGGACC AAAAGCACAT CGACGATCAG 
ATGAAGGACG AGGCCGCCTT CCTGCAGCGC AAGTATCCCA CTCTGGCCAC CCGGAACGGC 
ACGCCCTACT TGGCCAAGAC CCTCAACCGG CTCCTGATGC ACCACATCCG GGACTGCCTG 
CCAGATCTTA AGACTCGCGT CAACATCATG GCCACGCAAT TCCAATCGCT GCTGAACTCC 
TATGGCGAGG ATGTCTCCGA CAAGAGCCAG ACCCTGCTGC AGATCATCAC GAAGTTCTCC 
AGCGCCTACT GCTGCACAAT CGAGGGCACG GCCAGGAATA TCGAGACCAC GGAACTGTGC 
GGCGGTGCCC GGATGGGCTA CATTTTCCAC GAGACCTTCG GCCGCACCCT GGACTCCATT 
CACCCGCTGG CGGGTCTGAG CAAGATGGAC ATACTGACAG CCATCCGGAA TGCCACTGGT 
CCACGCCCGG CTTTGTTCGT TCCGGAGGTC TCGTTCGAAC TGCTAGTGAA GCGCCAGATT 
CGCCGCCTGG AGGAACCCTC CTTGCGCTGC GTGGAACTCA TTCACGAGGA GATGCAGCGC 
ATTGTTCAGC ATTGTGGCAA CGAAGTGCAG CAGGAGATGC TGCGCTTTCC CAAACTGCAC 
GAGAAGATTG TGGACGTGGT CACCCAGCTG CTGCGTCGAC GTCTGCCGCA CACCAACGTG 
ATGGTGGAGA ACATTGTGGC CATCGAGCTG GCCTACATCA ACACCAAGCA CCCCGACTTC 
CACAAGGATG CCGCTTTGGT GCCCAGTCTG CTGAAAACGG ACAGCGATCC CTACTCACAG 
ATAAATCTGG GGCAGCGGCG GGCCAATACA CCGCGAAACC ACATGTCGCC TCAGATTTCG 
TCGCACAGTG CTGGTTCACA GCAGCCGCAG CAGCAACAGC CGCCGCAGCC GAATTCCTCA 
CAGCAGCAAT ATAGCCAAGT GCATGAGCAG AACCACGTCG CCGAGAACTC GACGCCTTCG 
ATGGCCAGCA CATGGCTGTC AAACATTTTA CCGCCGGCAC CAACGCGTCC GGACAGCATT 
GAGAACTCGA CCAACAACAC TCCGGTTCAC AATAACATCG TGAGTCCAGT GAAGCCGGTC 
AATCTGCTGC CCGATGTGCC GGCCAACCAC AATCCACGTC GCCTCACTGA CAAGGAGCAG 
AAGGATTGCG ATGTCATCGA ACACCTGATC AAATCGTATT TCTACATTGT GCGCAAATCC 
ATACAAGACT CGGTTCCAAA GGCCATCATG CATTTCTTGG TTAACTACGT TAAGGACAAC 
TTGCAGAGCG AATTGGTTAC ACATCTGTAT AAGTCGGATA AGGCTGAAAC CCTGCTCAAC 
GAGTCCGATC ACATTGCAGT GCGCCGAAAA GAGGCGGCAG ATATGCTGAA GGCACTGACG 
CGAGCGAATC ACATCATCAG CGAAATCCGC GAGACCCACA TGTGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001259946.1
CDS	160..2367
Translation	MEALIPVINKLQDVFNTVGSDSIQLPQIVVLGSQSSGKSSVIESVVGRSFLPRGTGIVTRRPLVLQLIYSPLDDRENRSAENGTSNAEEWGRFLHTKKCFTDFDEIRKEIENETERAAGSNKGICPEPINLKIFSTHVVNLTLVDLPGITKVPVGDQPEDIEAQIKELVLKYIENPNSIILAVTAANTDMATSEALKLAKDVDPDGRRTLAVVTKLDLMDAGTDAIDILCGRVIPVKLGIIGVMNRSQKDIMDQKHIDDQMKDEAAFLQRKYPTLATRNGTPYLAKTLNRLLMHHIRDCLPDLKTRVNIMATQFQSLLNSYGEDVSDKSQTLLQIITKFSSAYCCTIEGTARNIETTELCGGARMGYIFHETFGRTLDSIHPLAGLSKMDILTAIRNATGPRPALFVPEVSFELLVKRQIRRLEEPSLRCVELIHEEMQRIVQHCGNEVQQEMLRFPKLHEKIVDVVTQLLRRRLPHTNVMVENIVAIELAYINTKHPDFHKDAALVPSLLKTDSDPYSQINLGQRRANTPRNHMSPQISSHSAGSQQPQQQQPPQPNSSQQQYSQVHEQNHVAENSTPSMASTWLSNILPPAPTRPDSIENSTNNTPVHNNIVSPVKPVNLLPDVPANHNPRRLTDKEQKDCDVIEHLIKSYFYIVRKSIQDSVPKAIMHFLVNYVKDNLQSELVTHLYKSDKAETLLNESDHIAVRRKEAADMLKALTRANHIISEIRETHMW

Target ORF information:

RefSeq Version	NM_001273017.1
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster dynamin related protein 1, transcript variant B (Drp1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001273017.1

ORF Insert Sequence:

ATGGAGGCCC TAATTCCGGT CATAAACAAG CTGCAGGACG TCTTCAACAC CGTGGGCTCC 
GACTCCATCC AATTGCCCCA AATTGTTGTT CTAGGCAGTC AGAGCTCCGG CAAGAGTTCG 
GTGATCGAGA GCGTTGTGGG ACGATCCTTT CTGCCCCGTG GAACTGGTAT TGTGACCCGT 
CGCCCACTGG TGCTCCAGCT GATCTACAGC CCACTCGATG ATCGCGAGAA TCGCTCGGCG 
GAAAATGGTA CGTCCAATGC CGAGGAGTGG GGCCGCTTCC TGCACACCAA GAAGTGCTTC 
ACGGACTTTG ACGAGATCCG CAAGGAGATC GAAAACGAAA CGGAGCGGGC GGCGGGCAGC 
AACAAGGGCA TCTGCCCGGA GCCCATCAAC CTGAAGATAT TCTCAACGCA CGTGGTCAAC 
CTAACGCTGG TGGATCTGCC CGGCATCACC AAGGTCCCGG TGGGCGATCA GCCGGAGGAT 
ATCGAGGCGC AGATCAAAGA ATTGGTCCTC AAGTACATTG AGAACCCGAA CTCCATCATT 
TTGGCTGTGA CGGCCGCCAA CACGGACATG GCCACCAGTG AGGCACTCAA GCTGGCCAAG 
GACGTGGACC CCGATGGCCG GCGCACTCTG GCCGTGGTCA CGAAACTGGA TCTCATGGAT 
GCCGGCACCG ATGCCATCGA CATCCTGTGC GGCCGGGTCA TTCCCGTCAA GCTGGGCATC 
ATCGGCGTTA TGAATCGCTC GCAGAAGGAC ATCATGGACC AAAAGCACAT CGACGATCAG 
ATGAAGGACG AGGCCGCCTT CCTGCAGCGC AAGTATCCCA CTCTGGCCAC CCGGAACGGC 
ACGCCCTACT TGGCCAAGAC CCTCAACCGG CTCCTGATGC ACCACATCCG GGACTGCCTG 
CCAGATCTTA AGACTCGCGT CAACATCATG GCCACGCAAT TCCAATCGCT GCTGAACTCC 
TATGGCGAGG ATGTCTCCGA CAAGAGCCAG ACCCTGCTGC AGATCATCAC GAAGTTCTCC 
AGCGCCTACT GCTGCACAAT CGAGGGCACG GCCAGGAATA TCGAGACCAC GGAACTGTGC 
GGCGGTGCCC GGATGGGCTA CATTTTCCAC GAGACCTTCG GCCGCACCCT GGACTCCATT 
CACCCGCTGG CGGGTCTGAG CAAGATGGAC ATACTGACAG CCATCCGGAA TGCCACTGGT 
CCACGCCCGG CTTTGTTCGT TCCGGAGGTC TCGTTCGAAC TGCTAGTGAA GCGCCAGATT 
CGCCGCCTGG AGGAACCCTC CTTGCGCTGC GTGGAACTCA TTCACGAGGA GATGCAGCGC 
ATTGTTCAGC ATTGTGGCAA CGAAGTGCAG CAGGAGATGC TGCGCTTTCC CAAACTGCAC 
GAGAAGATTG TGGACGTGGT CACCCAGCTG CTGCGTCGAC GTCTGCCGCA CACCAACGTG 
ATGGTGGAGA ACATTGTGGC CATCGAGCTG GCCTACATCA ACACCAAGCA CCCCGACTTC 
CACAAGGATG CCGCTTTGGT GCCCAGTCTG CTGAAAACGG ACAGCGATCC CTACTCACAG 
ATAAATCTGG GGCAGCGGCG GGCCAATACA CCGCGAAACC ACATGTCGCC TCAGATTTCG 
TCGCACAGTG CTGGTTCACA GCAGCCGCAG CAGCAACAGC CGCCGCAGCC GAATTCCTCA 
CAGCAGCAAT ATAGCCAAGT GCATGAGCAG AACCACGTCG CCGAGAACTC GACGCCTTCG 
ATGGCCAGCA CATGGCTGTC AAACATTTTA CCGCCGGCAC CAACGCGTCC GGACAGCATT 
GAGAACTCGA CCAACAACAC TCCGGTTCAC AATAACATCG TGAGTCCAGT GAAGCCGGTC 
AATCTGCTGC CCGATGTGCC GGCCAACCAC AATCCACGTC GCCTCACTGA CAAGGAGCAG 
AAGGATTGCG ATGTCATCGA ACACCTGATC AAATCGTATT TCTACATTGT GCGCAAATCC 
ATACAAGACT CGGTTCCAAA GGCCATCATG CATTTCTTGG TTAACTACGT TAAGGACAAC 
TTGCAGAGCG AATTGGTTAC ACATCTGTAT AAGTCGGATA AGGCTGAAAC CCTGCTCAAC 
GAGTCCGATC ACATTGCAGT GCGCCGAAAA GAGGCGGCAG ATATGCTGAA GGCACTGACG 
CGAGCGAATC ACATCATCAG CGAAATCCGC GAGACCCACA TGTGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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Drp1 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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