Cbs cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cbs
Entrez Gene ID	33081
Full Name	Cystathionine beta-synthase
Synonyms	CBS,CG1753,DmCBS,Dmel\CG1753,dCBS
General protein information	Preferred Names Cystathionine beta-synthase Names CG1753 gene product from transcript CG1753-RA CG1753-PA CG1753-PB CG1753-PC Cbs-PA Cbs-PB Cbs-PC cystathionine &bgr-synthase cystathionine &grb;-synthase cystathionine beta-synthase
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: X Map Location: 19E7-19E7

mRNA and Protein(s)

mRNA	Protein	Name
NM_134580.3	NP_608424.1	cystathionine beta-synthase, isoform A
NM_167726.2	NP_728384.1	cystathionine beta-synthase, isoform B
NM_001298579.1	NP_001285508.1	cystathionine beta-synthase, isoform C

Pathways from BioSystems

Homologies

Homo sapiens (human)	LOC102724560	XP_006723989.1
Neurospora crassa	NCU08216	XP_959306.1
Oryza sativa (rice)	Os06g0149700	NP_001056819.1
Xenopus tropicalis (tropical clawed frog)	cbs	NP_001008171.1
Homo sapiens (human)	CBS	NP_000062.1
Bos taurus (cattle)	CBS	NP_001095470.1
Mus musculus (house mouse)	Cbs	NP_001258282.1
Rattus norvegicus (Norway rat)	Cbs	NP_036654.2
Gallus gallus (chicken)	CBS	XP_416752.3
Drosophila melanogaster (fruit fly)	Cbs	NP_728384.1
Eremothecium gossypii	AGOS_AGR012C	NP_986677.2
Magnaporthe oryzae (rice blast fungus)	MGG_07384	XP_003711260.1
Canis lupus familiaris (dog)	CBS	XP_853796.2
Danio rerio (zebrafish)	cbsb	NP_001014367.2
Saccharomyces cerevisiae (baker's yeast)	CYS4	NP_011671.3
Kluyveromyces lactis	KLLA0F09317g	XP_455504.1
Pan troglodytes (chimpanzee)	CBS	XP_001143121.1
Danio rerio (zebrafish)	cbsa	NP_001104702.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP000162	XP_310977.5
Oryza sativa (rice)	Os06g0564700	NP_001057885.1
Oryza sativa (rice)	Os06g0564500	NP_001057884.1
Oryza sativa (rice)	Os06g0149900	NP_001056820.1

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The Fe(II) heme in DmCBS is less stable than that in human CBS, undergoing more facile reoxidation and ligand exchange.
Title: Comparative study of enzyme activity and heme reactivity in Drosophila melanogaster and Homo sapiens cystathionine ?-synthases.

The following Cbs gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cbs cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OFa02221	NM_134580.3 Latest version!	Drosophila melanogaster cystathionine beta-synthase, transcript variant A (Cbs), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00
OFa02221	NM_167726.2 Latest version!	Drosophila melanogaster cystathionine beta-synthase, transcript variant B (Cbs), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00
OFa02221	NM_001298579.1 Latest version!	Drosophila melanogaster cystathionine beta-synthase, transcript variant C (Cbs), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cbs ( NM_134580.3 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_608424.1 Drosophila melanogaster cystathionine beta-synthase, transcript variant A (Cbs), mRNA.

Price & Availability↑

CloneID	OFa02221
Clone ID Related Accession (Same CDS sequence)	NM_134580.3 , NM_167726.2 , NM_001298579.1
Accession Version	NM_134580.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1569bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	cystathionine beta-synthase, isoform A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NC_004354). On Jul 15, 2014 this sequence version replaced NM_134580.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGCCACAAC CGAAGCCATA CGAGAGGCCC GCGGACTTCA TCGATCCCGG CAAGCCGTCC 
AAGTGCAAAT GGCATCTGGG TACAGCCGAG AAGTCGCCCC ACATCCATCG GGGCATCGCC 
CACCGCCAGC AGATTACGCC CAACATCCTC GAGGTGATCG GATGCACGCC ACTGGTCAAG 
TTGAACAACA TTCCCGCCAG CGACGGCATC GAATGCGAGA TGTATGCCAA GTGCGAGTTC 
CTTAATCCGG GTGGATCAGT GAAGGACCGC ATTGGGTACC GCATGGTGCA GGACGCCGAG 
GAGCAGGGCC TGCTCAAGCC AGGCTACACC ATCATCGAAC CAACGTCTGG AAACACGGGC 
ATTGGACTGG CAATGGCCTG TGCCGTTAAG GGATACAAGT GCATTATCGT GATGCCGGAG 
AAGATGTCCA ACGAGAAGGT GTCCGCGCTG CGAACCCTCG GGGCCAAGAT CATACGTACT 
CCAACGGAGG CAGCCTACGA TTCGCCGGAG GGACTGATCT ACGTTGCTCA GCAGCTGCAG 
CGGGAAACGC CCAACTCGAT TGTCTTGGAT CAGTATCGCA ACGCTGGCAA TCCGCTGGCT 
CACTACGATG GCACTGCCGC CGAGATTCTG TGGCAGCTGG ACAACAAGGT CGATATGATA 
GTGGTCTCGG CGGGAACGGC GGGAACTATC AGTGGTATTG GGCGTAAGAT CAAGGAGCAG 
GTTCCCAGTT GCCAGATAGT CGGCGTGGAT CCCTATGGCT CGATCCTTGC CCGCCCTGCT 
GAGCTCAACA AGACCGATGT GCAATTCTAC GAGGTGGAGG GCATCGGCTA CGACTTTCCG 
CCCACCGTAT TCGATGACAC CGTCGTGGAT GTGTGGACGA AAATCGGCGA CTCAGACTGT 
TTCCCCATGA GCAGACGCCT GAACGCGGAG GAGGGTCTGT TGTGCGGCGG GTCCAGTGGC 
GGAGCGATGC ACGCTGCCCT CGAGCATGCC CGCAAATTGA AGAAAGGCCA GCGGTGCGTG 
GTCATTCTGC CCGATGGCAT ACGCAACTAC ATGACCAAGT TCGTGTCGGA CAACTGGATG 
GAGGCGCGCA ACTTCAAGGA GCCGGTAAAC GAGCACGGTC ACTGGTGGTG GAGCCTGGCC 
ATCGCGGAGT TGGAGCTACC CGCTCCCCCG GTCATTCTCA AGTCGGATGC AACTGTTGGT 
GAGGCTATTG CCCTGATGAA GAAACACCGC GTGGACCAGC TGCCCGTCGT GGATCAGGAT 
GATGGTTCTG TCCTGGGCGT CGTGGGTCAG GAGACGCTGA TCACGCAGAT CGTGAGCATG 
AACCGCCAGC AGTCCGATCC CGCAATCAAG GCGCTCAACA AACGAGTAAT CCGACTGAAC 
GAATCCGAGA TTCTGGGCAA GTTGGCCCGC GTCCTCGAAG TGGACCCCAG CGTGCTCATC 
CTGGGCAAGA ACCCGGCCGG CAAGGTGGAG CTCAAAGCTC TGGCCACCAA GCTGGACGTG 
ACCACTTTCA TTGCCGCCGG CAAGCAGAAG CCCAAGGCCA ATGGCACCAC CAACGGCGGC 
AGCCACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_608424.1
CDS	215..1783
Translation	MPQPKPYERPADFIDPGKPSKCKWHLGTAEKSPHIHRGIAHRQQITPNILEVIGCTPLVKLNNIPASDGIECEMYAKCEFLNPGGSVKDRIGYRMVQDAEEQGLLKPGYTIIEPTSGNTGIGLAMACAVKGYKCIIVMPEKMSNEKVSALRTLGAKIIRTPTEAAYDSPEGLIYVAQQLQRETPNSIVLDQYRNAGNPLAHYDGTAAEILWQLDNKVDMIVVSAGTAGTISGIGRKIKEQVPSCQIVGVDPYGSILARPAELNKTDVQFYEVEGIGYDFPPTVFDDTVVDVWTKIGDSDCFPMSRRLNAEEGLLCGGSSGGAMHAALEHARKLKKGQRCVVILPDGIRNYMTKFVSDNWMEARNFKEPVNEHGHWWWSLAIAELELPAPPVILKSDATVGEAIALMKKHRVDQLPVVDQDDGSVLGVVGQETLITQIVSMNRQQSDPAIKALNKRVIRLNESEILGKLARVLEVDPSVLILGKNPAGKVELKALATKLDVTTFIAAGKQKPKANGTTNGGSH

Target ORF information:

RefSeq Version	NM_134580.3
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster cystathionine beta-synthase, transcript variant A (Cbs), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_134580.3

ORF Insert Sequence:

ATGCCACAAC CGAAGCCATA CGAGAGGCCC GCGGACTTCA TCGATCCCGG CAAGCCGTCC 
AAGTGCAAAT GGCATCTGGG TACAGCCGAG AAGTCGCCCC ACATCCATCG GGGCATCGCC 
CACCGCCAGC AGATTACGCC CAACATCCTC GAGGTGATCG GATGCACGCC ACTGGTCAAG 
TTGAACAACA TTCCCGCCAG CGACGGCATC GAATGCGAGA TGTATGCCAA GTGCGAGTTC 
CTTAATCCGG GTGGATCAGT GAAGGACCGC ATTGGGTACC GCATGGTGCA GGACGCCGAG 
GAGCAGGGCC TGCTCAAGCC AGGCTACACC ATCATCGAAC CAACGTCTGG AAACACGGGC 
ATTGGACTGG CAATGGCCTG TGCCGTTAAG GGATACAAGT GCATTATCGT GATGCCGGAG 
AAGATGTCCA ACGAGAAGGT GTCCGCGCTG CGAACCCTCG GGGCCAAGAT CATACGTACT 
CCAACGGAGG CAGCCTACGA TTCGCCGGAG GGACTGATCT ACGTTGCTCA GCAGCTGCAG 
CGGGAAACGC CCAACTCGAT TGTCTTGGAT CAGTATCGCA ACGCTGGCAA TCCGCTGGCT 
CACTACGATG GCACTGCCGC CGAGATTCTG TGGCAGCTGG ACAACAAGGT CGATATGATA 
GTGGTCTCGG CGGGAACGGC GGGAACTATC AGTGGTATTG GGCGTAAGAT CAAGGAGCAG 
GTTCCCAGTT GCCAGATAGT CGGCGTGGAT CCCTATGGCT CGATCCTTGC CCGCCCTGCT 
GAGCTCAACA AGACCGATGT GCAATTCTAC GAGGTGGAGG GCATCGGCTA CGACTTTCCG 
CCCACCGTAT TCGATGACAC CGTCGTGGAT GTGTGGACGA AAATCGGCGA CTCAGACTGT 
TTCCCCATGA GCAGACGCCT GAACGCGGAG GAGGGTCTGT TGTGCGGCGG GTCCAGTGGC 
GGAGCGATGC ACGCTGCCCT CGAGCATGCC CGCAAATTGA AGAAAGGCCA GCGGTGCGTG 
GTCATTCTGC CCGATGGCAT ACGCAACTAC ATGACCAAGT TCGTGTCGGA CAACTGGATG 
GAGGCGCGCA ACTTCAAGGA GCCGGTAAAC GAGCACGGTC ACTGGTGGTG GAGCCTGGCC 
ATCGCGGAGT TGGAGCTACC CGCTCCCCCG GTCATTCTCA AGTCGGATGC AACTGTTGGT 
GAGGCTATTG CCCTGATGAA GAAACACCGC GTGGACCAGC TGCCCGTCGT GGATCAGGAT 
GATGGTTCTG TCCTGGGCGT CGTGGGTCAG GAGACGCTGA TCACGCAGAT CGTGAGCATG 
AACCGCCAGC AGTCCGATCC CGCAATCAAG GCGCTCAACA AACGAGTAAT CCGACTGAAC 
GAATCCGAGA TTCTGGGCAA GTTGGCCCGC GTCCTCGAAG TGGACCCCAG CGTGCTCATC 
CTGGGCAAGA ACCCGGCCGG CAAGGTGGAG CTCAAAGCTC TGGCCACCAA GCTGGACGTG 
ACCACTTTCA TTGCCGCCGG CAAGCAGAAG CCCAAGGCCA ATGGCACCAC CAACGGCGGC 
AGCCACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cbs ( NM_167726.2 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_728384.1 Drosophila melanogaster cystathionine beta-synthase, transcript variant B (Cbs), mRNA.

Price & Availability↑

CloneID	OFa02221
Clone ID Related Accession (Same CDS sequence)	NM_134580.3 , NM_167726.2 , NM_001298579.1
Accession Version	NM_167726.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1569bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	cystathionine beta-synthase, isoform B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NC_004354). On Jul 15, 2014 this sequence version replaced NM_167726.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGCCACAAC CGAAGCCATA CGAGAGGCCC GCGGACTTCA TCGATCCCGG CAAGCCGTCC 
AAGTGCAAAT GGCATCTGGG TACAGCCGAG AAGTCGCCCC ACATCCATCG GGGCATCGCC 
CACCGCCAGC AGATTACGCC CAACATCCTC GAGGTGATCG GATGCACGCC ACTGGTCAAG 
TTGAACAACA TTCCCGCCAG CGACGGCATC GAATGCGAGA TGTATGCCAA GTGCGAGTTC 
CTTAATCCGG GTGGATCAGT GAAGGACCGC ATTGGGTACC GCATGGTGCA GGACGCCGAG 
GAGCAGGGCC TGCTCAAGCC AGGCTACACC ATCATCGAAC CAACGTCTGG AAACACGGGC 
ATTGGACTGG CAATGGCCTG TGCCGTTAAG GGATACAAGT GCATTATCGT GATGCCGGAG 
AAGATGTCCA ACGAGAAGGT GTCCGCGCTG CGAACCCTCG GGGCCAAGAT CATACGTACT 
CCAACGGAGG CAGCCTACGA TTCGCCGGAG GGACTGATCT ACGTTGCTCA GCAGCTGCAG 
CGGGAAACGC CCAACTCGAT TGTCTTGGAT CAGTATCGCA ACGCTGGCAA TCCGCTGGCT 
CACTACGATG GCACTGCCGC CGAGATTCTG TGGCAGCTGG ACAACAAGGT CGATATGATA 
GTGGTCTCGG CGGGAACGGC GGGAACTATC AGTGGTATTG GGCGTAAGAT CAAGGAGCAG 
GTTCCCAGTT GCCAGATAGT CGGCGTGGAT CCCTATGGCT CGATCCTTGC CCGCCCTGCT 
GAGCTCAACA AGACCGATGT GCAATTCTAC GAGGTGGAGG GCATCGGCTA CGACTTTCCG 
CCCACCGTAT TCGATGACAC CGTCGTGGAT GTGTGGACGA AAATCGGCGA CTCAGACTGT 
TTCCCCATGA GCAGACGCCT GAACGCGGAG GAGGGTCTGT TGTGCGGCGG GTCCAGTGGC 
GGAGCGATGC ACGCTGCCCT CGAGCATGCC CGCAAATTGA AGAAAGGCCA GCGGTGCGTG 
GTCATTCTGC CCGATGGCAT ACGCAACTAC ATGACCAAGT TCGTGTCGGA CAACTGGATG 
GAGGCGCGCA ACTTCAAGGA GCCGGTAAAC GAGCACGGTC ACTGGTGGTG GAGCCTGGCC 
ATCGCGGAGT TGGAGCTACC CGCTCCCCCG GTCATTCTCA AGTCGGATGC AACTGTTGGT 
GAGGCTATTG CCCTGATGAA GAAACACCGC GTGGACCAGC TGCCCGTCGT GGATCAGGAT 
GATGGTTCTG TCCTGGGCGT CGTGGGTCAG GAGACGCTGA TCACGCAGAT CGTGAGCATG 
AACCGCCAGC AGTCCGATCC CGCAATCAAG GCGCTCAACA AACGAGTAAT CCGACTGAAC 
GAATCCGAGA TTCTGGGCAA GTTGGCCCGC GTCCTCGAAG TGGACCCCAG CGTGCTCATC 
CTGGGCAAGA ACCCGGCCGG CAAGGTGGAG CTCAAAGCTC TGGCCACCAA GCTGGACGTG 
ACCACTTTCA TTGCCGCCGG CAAGCAGAAG CCCAAGGCCA ATGGCACCAC CAACGGCGGC 
AGCCACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_728384.1
CDS	294..1862
Translation	MPQPKPYERPADFIDPGKPSKCKWHLGTAEKSPHIHRGIAHRQQITPNILEVIGCTPLVKLNNIPASDGIECEMYAKCEFLNPGGSVKDRIGYRMVQDAEEQGLLKPGYTIIEPTSGNTGIGLAMACAVKGYKCIIVMPEKMSNEKVSALRTLGAKIIRTPTEAAYDSPEGLIYVAQQLQRETPNSIVLDQYRNAGNPLAHYDGTAAEILWQLDNKVDMIVVSAGTAGTISGIGRKIKEQVPSCQIVGVDPYGSILARPAELNKTDVQFYEVEGIGYDFPPTVFDDTVVDVWTKIGDSDCFPMSRRLNAEEGLLCGGSSGGAMHAALEHARKLKKGQRCVVILPDGIRNYMTKFVSDNWMEARNFKEPVNEHGHWWWSLAIAELELPAPPVILKSDATVGEAIALMKKHRVDQLPVVDQDDGSVLGVVGQETLITQIVSMNRQQSDPAIKALNKRVIRLNESEILGKLARVLEVDPSVLILGKNPAGKVELKALATKLDVTTFIAAGKQKPKANGTTNGGSH

Target ORF information:

RefSeq Version	NM_167726.2
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster cystathionine beta-synthase, transcript variant B (Cbs), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_167726.2

ORF Insert Sequence:

ATGCCACAAC CGAAGCCATA CGAGAGGCCC GCGGACTTCA TCGATCCCGG CAAGCCGTCC 
AAGTGCAAAT GGCATCTGGG TACAGCCGAG AAGTCGCCCC ACATCCATCG GGGCATCGCC 
CACCGCCAGC AGATTACGCC CAACATCCTC GAGGTGATCG GATGCACGCC ACTGGTCAAG 
TTGAACAACA TTCCCGCCAG CGACGGCATC GAATGCGAGA TGTATGCCAA GTGCGAGTTC 
CTTAATCCGG GTGGATCAGT GAAGGACCGC ATTGGGTACC GCATGGTGCA GGACGCCGAG 
GAGCAGGGCC TGCTCAAGCC AGGCTACACC ATCATCGAAC CAACGTCTGG AAACACGGGC 
ATTGGACTGG CAATGGCCTG TGCCGTTAAG GGATACAAGT GCATTATCGT GATGCCGGAG 
AAGATGTCCA ACGAGAAGGT GTCCGCGCTG CGAACCCTCG GGGCCAAGAT CATACGTACT 
CCAACGGAGG CAGCCTACGA TTCGCCGGAG GGACTGATCT ACGTTGCTCA GCAGCTGCAG 
CGGGAAACGC CCAACTCGAT TGTCTTGGAT CAGTATCGCA ACGCTGGCAA TCCGCTGGCT 
CACTACGATG GCACTGCCGC CGAGATTCTG TGGCAGCTGG ACAACAAGGT CGATATGATA 
GTGGTCTCGG CGGGAACGGC GGGAACTATC AGTGGTATTG GGCGTAAGAT CAAGGAGCAG 
GTTCCCAGTT GCCAGATAGT CGGCGTGGAT CCCTATGGCT CGATCCTTGC CCGCCCTGCT 
GAGCTCAACA AGACCGATGT GCAATTCTAC GAGGTGGAGG GCATCGGCTA CGACTTTCCG 
CCCACCGTAT TCGATGACAC CGTCGTGGAT GTGTGGACGA AAATCGGCGA CTCAGACTGT 
TTCCCCATGA GCAGACGCCT GAACGCGGAG GAGGGTCTGT TGTGCGGCGG GTCCAGTGGC 
GGAGCGATGC ACGCTGCCCT CGAGCATGCC CGCAAATTGA AGAAAGGCCA GCGGTGCGTG 
GTCATTCTGC CCGATGGCAT ACGCAACTAC ATGACCAAGT TCGTGTCGGA CAACTGGATG 
GAGGCGCGCA ACTTCAAGGA GCCGGTAAAC GAGCACGGTC ACTGGTGGTG GAGCCTGGCC 
ATCGCGGAGT TGGAGCTACC CGCTCCCCCG GTCATTCTCA AGTCGGATGC AACTGTTGGT 
GAGGCTATTG CCCTGATGAA GAAACACCGC GTGGACCAGC TGCCCGTCGT GGATCAGGAT 
GATGGTTCTG TCCTGGGCGT CGTGGGTCAG GAGACGCTGA TCACGCAGAT CGTGAGCATG 
AACCGCCAGC AGTCCGATCC CGCAATCAAG GCGCTCAACA AACGAGTAAT CCGACTGAAC 
GAATCCGAGA TTCTGGGCAA GTTGGCCCGC GTCCTCGAAG TGGACCCCAG CGTGCTCATC 
CTGGGCAAGA ACCCGGCCGG CAAGGTGGAG CTCAAAGCTC TGGCCACCAA GCTGGACGTG 
ACCACTTTCA TTGCCGCCGG CAAGCAGAAG CCCAAGGCCA ATGGCACCAC CAACGGCGGC 
AGCCACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cbs ( NM_001298579.1 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_001285508.1 Drosophila melanogaster cystathionine beta-synthase, transcript variant C (Cbs), mRNA.

Price & Availability↑

CloneID	OFa02221
Clone ID Related Accession (Same CDS sequence)	NM_134580.3 , NM_167726.2 , NM_001298579.1
Accession Version	NM_001298579.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1569bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	cystathionine beta-synthase, isoform C
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NC_004354). ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGCCACAAC CGAAGCCATA CGAGAGGCCC GCGGACTTCA TCGATCCCGG CAAGCCGTCC 
AAGTGCAAAT GGCATCTGGG TACAGCCGAG AAGTCGCCCC ACATCCATCG GGGCATCGCC 
CACCGCCAGC AGATTACGCC CAACATCCTC GAGGTGATCG GATGCACGCC ACTGGTCAAG 
TTGAACAACA TTCCCGCCAG CGACGGCATC GAATGCGAGA TGTATGCCAA GTGCGAGTTC 
CTTAATCCGG GTGGATCAGT GAAGGACCGC ATTGGGTACC GCATGGTGCA GGACGCCGAG 
GAGCAGGGCC TGCTCAAGCC AGGCTACACC ATCATCGAAC CAACGTCTGG AAACACGGGC 
ATTGGACTGG CAATGGCCTG TGCCGTTAAG GGATACAAGT GCATTATCGT GATGCCGGAG 
AAGATGTCCA ACGAGAAGGT GTCCGCGCTG CGAACCCTCG GGGCCAAGAT CATACGTACT 
CCAACGGAGG CAGCCTACGA TTCGCCGGAG GGACTGATCT ACGTTGCTCA GCAGCTGCAG 
CGGGAAACGC CCAACTCGAT TGTCTTGGAT CAGTATCGCA ACGCTGGCAA TCCGCTGGCT 
CACTACGATG GCACTGCCGC CGAGATTCTG TGGCAGCTGG ACAACAAGGT CGATATGATA 
GTGGTCTCGG CGGGAACGGC GGGAACTATC AGTGGTATTG GGCGTAAGAT CAAGGAGCAG 
GTTCCCAGTT GCCAGATAGT CGGCGTGGAT CCCTATGGCT CGATCCTTGC CCGCCCTGCT 
GAGCTCAACA AGACCGATGT GCAATTCTAC GAGGTGGAGG GCATCGGCTA CGACTTTCCG 
CCCACCGTAT TCGATGACAC CGTCGTGGAT GTGTGGACGA AAATCGGCGA CTCAGACTGT 
TTCCCCATGA GCAGACGCCT GAACGCGGAG GAGGGTCTGT TGTGCGGCGG GTCCAGTGGC 
GGAGCGATGC ACGCTGCCCT CGAGCATGCC CGCAAATTGA AGAAAGGCCA GCGGTGCGTG 
GTCATTCTGC CCGATGGCAT ACGCAACTAC ATGACCAAGT TCGTGTCGGA CAACTGGATG 
GAGGCGCGCA ACTTCAAGGA GCCGGTAAAC GAGCACGGTC ACTGGTGGTG GAGCCTGGCC 
ATCGCGGAGT TGGAGCTACC CGCTCCCCCG GTCATTCTCA AGTCGGATGC AACTGTTGGT 
GAGGCTATTG CCCTGATGAA GAAACACCGC GTGGACCAGC TGCCCGTCGT GGATCAGGAT 
GATGGTTCTG TCCTGGGCGT CGTGGGTCAG GAGACGCTGA TCACGCAGAT CGTGAGCATG 
AACCGCCAGC AGTCCGATCC CGCAATCAAG GCGCTCAACA AACGAGTAAT CCGACTGAAC 
GAATCCGAGA TTCTGGGCAA GTTGGCCCGC GTCCTCGAAG TGGACCCCAG CGTGCTCATC 
CTGGGCAAGA ACCCGGCCGG CAAGGTGGAG CTCAAAGCTC TGGCCACCAA GCTGGACGTG 
ACCACTTTCA TTGCCGCCGG CAAGCAGAAG CCCAAGGCCA ATGGCACCAC CAACGGCGGC 
AGCCACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001285508.1
CDS	92..1660
Translation	MPQPKPYERPADFIDPGKPSKCKWHLGTAEKSPHIHRGIAHRQQITPNILEVIGCTPLVKLNNIPASDGIECEMYAKCEFLNPGGSVKDRIGYRMVQDAEEQGLLKPGYTIIEPTSGNTGIGLAMACAVKGYKCIIVMPEKMSNEKVSALRTLGAKIIRTPTEAAYDSPEGLIYVAQQLQRETPNSIVLDQYRNAGNPLAHYDGTAAEILWQLDNKVDMIVVSAGTAGTISGIGRKIKEQVPSCQIVGVDPYGSILARPAELNKTDVQFYEVEGIGYDFPPTVFDDTVVDVWTKIGDSDCFPMSRRLNAEEGLLCGGSSGGAMHAALEHARKLKKGQRCVVILPDGIRNYMTKFVSDNWMEARNFKEPVNEHGHWWWSLAIAELELPAPPVILKSDATVGEAIALMKKHRVDQLPVVDQDDGSVLGVVGQETLITQIVSMNRQQSDPAIKALNKRVIRLNESEILGKLARVLEVDPSVLILGKNPAGKVELKALATKLDVTTFIAAGKQKPKANGTTNGGSH

Target ORF information:

RefSeq Version	NM_001298579.1
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster cystathionine beta-synthase, transcript variant C (Cbs), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001298579.1

ORF Insert Sequence:

ATGCCACAAC CGAAGCCATA CGAGAGGCCC GCGGACTTCA TCGATCCCGG CAAGCCGTCC 
AAGTGCAAAT GGCATCTGGG TACAGCCGAG AAGTCGCCCC ACATCCATCG GGGCATCGCC 
CACCGCCAGC AGATTACGCC CAACATCCTC GAGGTGATCG GATGCACGCC ACTGGTCAAG 
TTGAACAACA TTCCCGCCAG CGACGGCATC GAATGCGAGA TGTATGCCAA GTGCGAGTTC 
CTTAATCCGG GTGGATCAGT GAAGGACCGC ATTGGGTACC GCATGGTGCA GGACGCCGAG 
GAGCAGGGCC TGCTCAAGCC AGGCTACACC ATCATCGAAC CAACGTCTGG AAACACGGGC 
ATTGGACTGG CAATGGCCTG TGCCGTTAAG GGATACAAGT GCATTATCGT GATGCCGGAG 
AAGATGTCCA ACGAGAAGGT GTCCGCGCTG CGAACCCTCG GGGCCAAGAT CATACGTACT 
CCAACGGAGG CAGCCTACGA TTCGCCGGAG GGACTGATCT ACGTTGCTCA GCAGCTGCAG 
CGGGAAACGC CCAACTCGAT TGTCTTGGAT CAGTATCGCA ACGCTGGCAA TCCGCTGGCT 
CACTACGATG GCACTGCCGC CGAGATTCTG TGGCAGCTGG ACAACAAGGT CGATATGATA 
GTGGTCTCGG CGGGAACGGC GGGAACTATC AGTGGTATTG GGCGTAAGAT CAAGGAGCAG 
GTTCCCAGTT GCCAGATAGT CGGCGTGGAT CCCTATGGCT CGATCCTTGC CCGCCCTGCT 
GAGCTCAACA AGACCGATGT GCAATTCTAC GAGGTGGAGG GCATCGGCTA CGACTTTCCG 
CCCACCGTAT TCGATGACAC CGTCGTGGAT GTGTGGACGA AAATCGGCGA CTCAGACTGT 
TTCCCCATGA GCAGACGCCT GAACGCGGAG GAGGGTCTGT TGTGCGGCGG GTCCAGTGGC 
GGAGCGATGC ACGCTGCCCT CGAGCATGCC CGCAAATTGA AGAAAGGCCA GCGGTGCGTG 
GTCATTCTGC CCGATGGCAT ACGCAACTAC ATGACCAAGT TCGTGTCGGA CAACTGGATG 
GAGGCGCGCA ACTTCAAGGA GCCGGTAAAC GAGCACGGTC ACTGGTGGTG GAGCCTGGCC 
ATCGCGGAGT TGGAGCTACC CGCTCCCCCG GTCATTCTCA AGTCGGATGC AACTGTTGGT 
GAGGCTATTG CCCTGATGAA GAAACACCGC GTGGACCAGC TGCCCGTCGT GGATCAGGAT 
GATGGTTCTG TCCTGGGCGT CGTGGGTCAG GAGACGCTGA TCACGCAGAT CGTGAGCATG 
AACCGCCAGC AGTCCGATCC CGCAATCAAG GCGCTCAACA AACGAGTAAT CCGACTGAAC 
GAATCCGAGA TTCTGGGCAA GTTGGCCCGC GTCCTCGAAG TGGACCCCAG CGTGCTCATC 
CTGGGCAAGA ACCCGGCCGG CAAGGTGGAG CTCAAAGCTC TGGCCACCAA GCTGGACGTG 
ACCACTTTCA TTGCCGCCGG CAAGCAGAAG CCCAAGGCCA ATGGCACCAC CAACGGCGGC 
AGCCACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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Cbs cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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