parvin cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	parvin
Entrez Gene ID	32990
Full Name	CG32528 gene product from transcript CG32528-RB
Synonyms	CG12533,CG32528,Dmel\CG32528
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: X Map Location: 18E5-18F1

mRNA and Protein(s)

mRNA	Protein	Name
NM_134508.3	NP_608352.2	parvin, isoform A
NM_001298535.1	NP_001285464.1	parvin, isoform B

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	parvb	NP_956020.1
Homo sapiens (human)	PARVB	NP_037459.2
Pan troglodytes (chimpanzee)	PARVB	XP_003317342.1
Xenopus tropicalis (tropical clawed frog)	parvb	NP_001005624.1
Canis lupus familiaris (dog)	PARVB	XP_005625818.1
Drosophila melanogaster (fruit fly)	parvin	NP_608352.2
Bos taurus (cattle)	PARVB	NP_001095769.1
Mus musculus (house mouse)	Parvb	NP_573395.1
Rattus norvegicus (Norway rat)	Parvb	NP_001128252.1
Gallus gallus (chicken)	PARVB	XP_416459.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002356	XP_312593.4
	LOC715859	XP_001106273.2

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Parvin is localized at sites of integrin adhesion during embryogenesis.
Title: Functional analysis of parvin and different modes of IPP-complex assembly at integrin sites during Drosophila development.

Thus, distinct genetic interactions of Parvin occur in different cell types and second site modifier screens are required to uncover such genetic circuits
Title: Parvin overexpression uncovers tissue-specific genetic pathways and disrupts F-actin to induce apoptosis in the developing epithelia in Drosophila.

The following parvin gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the parvin cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OFa02178	NM_134508.3 Latest version!	Drosophila melanogaster parvin, transcript variant A (parvin), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00
OFa02178	NM_001298535.1 Latest version!	Drosophila melanogaster parvin, transcript variant B (parvin), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

parvin ( NM_134508.3 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_608352.2 Drosophila melanogaster parvin, transcript variant A (parvin), mRNA.

Price & Availability↑

CloneID	OFa02178
Clone ID Related Accession (Same CDS sequence)	NM_134508.3 , NM_001298535.1
Accession Version	NM_134508.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1104bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	parvin, isoform A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NC_004354). On Jul 15, 2014 this sequence version replaced NM_134508.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGTCCACAC TGAACCGCCC TAAATCCCCG CACACGCCCA CCGCCATTAA AAAGGGCGAG 
AAGGAGGACA GCTTCTGGGA CAAGTTCAGC ACTTTGGGCC GCAAACGCGG CACCCGCGAA 
GTGAAGAAGG TCCAAGAGGA GGGCAAGTAC GCCATCGACT CGCCTGGATC GCCCAGCCAG 
TATGACATCC CGCCGGAGGA CTATGCCCTG CGCGAGCACG AACAGCGCGC CGTCATCGAT 
CCACAGTCCA TCAGTGATCC CCAGGTGATA AAGCTGCAGC GCATCCTCGT CGACTGGATC 
AACGACGAGC TGGCCGAGCA GCGCATAATT GTTCAGCACC TGGAAGAGGA CATGTATGAC 
GGCCAGGTGC TGCACAAGCT GTGGGAGAAG CTCACCGGCA AGAAGCTGGA CGTTCCTGAG 
GTCACCCAGT CAGAGCAGGG CCAGCACGAG AAGCTCAACA TCGTCCTGAA GGCCGTCAAC 
CATACACTCG GCTTTCACCA AAAGATTCCC AAGTGGTCGG TGGCCAGCGT GCACTCGAAG 
AACATTGTGG CCATATTACA TCTGCTGGTG GCACTGGTGC GTCACTTCCG GGCGCCCGTT 
CGCCTGCCAG AGAACGTGTT CGTGACCGTC GTGATTGCGG AGAAGAATGC GGGCGTGCTG 
AACGCGCAGA AGTTCCAGGA GCAGATAACG TCCGAGTACG ACGACCTGGG CATGCGCTGC 
GAAAAGGACG CCTTCGACAC GCTGATCGAC TGTGCGCCGG ACAAGCTGGC CGTGGTGAAG 
AAGTCCTTGA TCACGTTCGT GAACAAGCAC CTGGCCAAGC TGAACTTTGA GATCAGCGAT 
CTGAACACGG ACTTTCGCGA CGGCGTATAC CTGTGCCTGC TGATGGGCCT GCTCGGTGGA 
TTCTTTGTGC CGCTGCACGA GTTCCATTTG ACGCCGCAGG ACGTGGATCA GATGGTCAGC 
AACGTGGCCT TCGCCTTCGA CCTGATGCAG GACGTGGGCC TGCCCAAACC AAAGGCGCGG 
CCGGAGGACA TCGTGAACAT GGACCTCAAG TCCACCCTGC GCGTCCTATA CAGCCTGTTC 
ACCATGTTCA GGGACTTCGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_608352.2
CDS	110..1213
Translation	MSTLNRPKSPHTPTAIKKGEKEDSFWDKFSTLGRKRGTREVKKVQEEGKYAIDSPGSPSQYDIPPEDYALREHEQRAVIDPQSISDPQVIKLQRILVDWINDELAEQRIIVQHLEEDMYDGQVLHKLWEKLTGKKLDVPEVTQSEQGQHEKLNIVLKAVNHTLGFHQKIPKWSVASVHSKNIVAILHLLVALVRHFRAPVRLPENVFVTVVIAEKNAGVLNAQKFQEQITSEYDDLGMRCEKDAFDTLIDCAPDKLAVVKKSLITFVNKHLAKLNFEISDLNTDFRDGVYLCLLMGLLGGFFVPLHEFHLTPQDVDQMVSNVAFAFDLMQDVGLPKPKARPEDIVNMDLKSTLRVLYSLFTMFRDFA

Target ORF information:

RefSeq Version	NM_134508.3
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster parvin, transcript variant A (parvin), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_134508.3

ORF Insert Sequence:

ATGTCCACAC TGAACCGCCC TAAATCCCCG CACACGCCCA CCGCCATTAA AAAGGGCGAG 
AAGGAGGACA GCTTCTGGGA CAAGTTCAGC ACTTTGGGCC GCAAACGCGG CACCCGCGAA 
GTGAAGAAGG TCCAAGAGGA GGGCAAGTAC GCCATCGACT CGCCTGGATC GCCCAGCCAG 
TATGACATCC CGCCGGAGGA CTATGCCCTG CGCGAGCACG AACAGCGCGC CGTCATCGAT 
CCACAGTCCA TCAGTGATCC CCAGGTGATA AAGCTGCAGC GCATCCTCGT CGACTGGATC 
AACGACGAGC TGGCCGAGCA GCGCATAATT GTTCAGCACC TGGAAGAGGA CATGTATGAC 
GGCCAGGTGC TGCACAAGCT GTGGGAGAAG CTCACCGGCA AGAAGCTGGA CGTTCCTGAG 
GTCACCCAGT CAGAGCAGGG CCAGCACGAG AAGCTCAACA TCGTCCTGAA GGCCGTCAAC 
CATACACTCG GCTTTCACCA AAAGATTCCC AAGTGGTCGG TGGCCAGCGT GCACTCGAAG 
AACATTGTGG CCATATTACA TCTGCTGGTG GCACTGGTGC GTCACTTCCG GGCGCCCGTT 
CGCCTGCCAG AGAACGTGTT CGTGACCGTC GTGATTGCGG AGAAGAATGC GGGCGTGCTG 
AACGCGCAGA AGTTCCAGGA GCAGATAACG TCCGAGTACG ACGACCTGGG CATGCGCTGC 
GAAAAGGACG CCTTCGACAC GCTGATCGAC TGTGCGCCGG ACAAGCTGGC CGTGGTGAAG 
AAGTCCTTGA TCACGTTCGT GAACAAGCAC CTGGCCAAGC TGAACTTTGA GATCAGCGAT 
CTGAACACGG ACTTTCGCGA CGGCGTATAC CTGTGCCTGC TGATGGGCCT GCTCGGTGGA 
TTCTTTGTGC CGCTGCACGA GTTCCATTTG ACGCCGCAGG ACGTGGATCA GATGGTCAGC 
AACGTGGCCT TCGCCTTCGA CCTGATGCAG GACGTGGGCC TGCCCAAACC AAAGGCGCGG 
CCGGAGGACA TCGTGAACAT GGACCTCAAG TCCACCCTGC GCGTCCTATA CAGCCTGTTC 
ACCATGTTCA GGGACTTCGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

parvin ( NM_001298535.1 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_001285464.1 Drosophila melanogaster parvin, transcript variant B (parvin), mRNA.

Price & Availability↑

CloneID	OFa02178
Clone ID Related Accession (Same CDS sequence)	NM_134508.3 , NM_001298535.1
Accession Version	NM_001298535.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1104bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	parvin, isoform B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NC_004354). ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGTCCACAC TGAACCGCCC TAAATCCCCG CACACGCCCA CCGCCATTAA AAAGGGCGAG 
AAGGAGGACA GCTTCTGGGA CAAGTTCAGC ACTTTGGGCC GCAAACGCGG CACCCGCGAA 
GTGAAGAAGG TCCAAGAGGA GGGCAAGTAC GCCATCGACT CGCCTGGATC GCCCAGCCAG 
TATGACATCC CGCCGGAGGA CTATGCCCTG CGCGAGCACG AACAGCGCGC CGTCATCGAT 
CCACAGTCCA TCAGTGATCC CCAGGTGATA AAGCTGCAGC GCATCCTCGT CGACTGGATC 
AACGACGAGC TGGCCGAGCA GCGCATAATT GTTCAGCACC TGGAAGAGGA CATGTATGAC 
GGCCAGGTGC TGCACAAGCT GTGGGAGAAG CTCACCGGCA AGAAGCTGGA CGTTCCTGAG 
GTCACCCAGT CAGAGCAGGG CCAGCACGAG AAGCTCAACA TCGTCCTGAA GGCCGTCAAC 
CATACACTCG GCTTTCACCA AAAGATTCCC AAGTGGTCGG TGGCCAGCGT GCACTCGAAG 
AACATTGTGG CCATATTACA TCTGCTGGTG GCACTGGTGC GTCACTTCCG GGCGCCCGTT 
CGCCTGCCAG AGAACGTGTT CGTGACCGTC GTGATTGCGG AGAAGAATGC GGGCGTGCTG 
AACGCGCAGA AGTTCCAGGA GCAGATAACG TCCGAGTACG ACGACCTGGG CATGCGCTGC 
GAAAAGGACG CCTTCGACAC GCTGATCGAC TGTGCGCCGG ACAAGCTGGC CGTGGTGAAG 
AAGTCCTTGA TCACGTTCGT GAACAAGCAC CTGGCCAAGC TGAACTTTGA GATCAGCGAT 
CTGAACACGG ACTTTCGCGA CGGCGTATAC CTGTGCCTGC TGATGGGCCT GCTCGGTGGA 
TTCTTTGTGC CGCTGCACGA GTTCCATTTG ACGCCGCAGG ACGTGGATCA GATGGTCAGC 
AACGTGGCCT TCGCCTTCGA CCTGATGCAG GACGTGGGCC TGCCCAAACC AAAGGCGCGG 
CCGGAGGACA TCGTGAACAT GGACCTCAAG TCCACCCTGC GCGTCCTATA CAGCCTGTTC 
ACCATGTTCA GGGACTTCGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001285464.1
CDS	149..1252
Translation	MSTLNRPKSPHTPTAIKKGEKEDSFWDKFSTLGRKRGTREVKKVQEEGKYAIDSPGSPSQYDIPPEDYALREHEQRAVIDPQSISDPQVIKLQRILVDWINDELAEQRIIVQHLEEDMYDGQVLHKLWEKLTGKKLDVPEVTQSEQGQHEKLNIVLKAVNHTLGFHQKIPKWSVASVHSKNIVAILHLLVALVRHFRAPVRLPENVFVTVVIAEKNAGVLNAQKFQEQITSEYDDLGMRCEKDAFDTLIDCAPDKLAVVKKSLITFVNKHLAKLNFEISDLNTDFRDGVYLCLLMGLLGGFFVPLHEFHLTPQDVDQMVSNVAFAFDLMQDVGLPKPKARPEDIVNMDLKSTLRVLYSLFTMFRDFA

Target ORF information:

RefSeq Version	NM_001298535.1
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster parvin, transcript variant B (parvin), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001298535.1

ORF Insert Sequence:

ATGTCCACAC TGAACCGCCC TAAATCCCCG CACACGCCCA CCGCCATTAA AAAGGGCGAG 
AAGGAGGACA GCTTCTGGGA CAAGTTCAGC ACTTTGGGCC GCAAACGCGG CACCCGCGAA 
GTGAAGAAGG TCCAAGAGGA GGGCAAGTAC GCCATCGACT CGCCTGGATC GCCCAGCCAG 
TATGACATCC CGCCGGAGGA CTATGCCCTG CGCGAGCACG AACAGCGCGC CGTCATCGAT 
CCACAGTCCA TCAGTGATCC CCAGGTGATA AAGCTGCAGC GCATCCTCGT CGACTGGATC 
AACGACGAGC TGGCCGAGCA GCGCATAATT GTTCAGCACC TGGAAGAGGA CATGTATGAC 
GGCCAGGTGC TGCACAAGCT GTGGGAGAAG CTCACCGGCA AGAAGCTGGA CGTTCCTGAG 
GTCACCCAGT CAGAGCAGGG CCAGCACGAG AAGCTCAACA TCGTCCTGAA GGCCGTCAAC 
CATACACTCG GCTTTCACCA AAAGATTCCC AAGTGGTCGG TGGCCAGCGT GCACTCGAAG 
AACATTGTGG CCATATTACA TCTGCTGGTG GCACTGGTGC GTCACTTCCG GGCGCCCGTT 
CGCCTGCCAG AGAACGTGTT CGTGACCGTC GTGATTGCGG AGAAGAATGC GGGCGTGCTG 
AACGCGCAGA AGTTCCAGGA GCAGATAACG TCCGAGTACG ACGACCTGGG CATGCGCTGC 
GAAAAGGACG CCTTCGACAC GCTGATCGAC TGTGCGCCGG ACAAGCTGGC CGTGGTGAAG 
AAGTCCTTGA TCACGTTCGT GAACAAGCAC CTGGCCAAGC TGAACTTTGA GATCAGCGAT 
CTGAACACGG ACTTTCGCGA CGGCGTATAC CTGTGCCTGC TGATGGGCCT GCTCGGTGGA 
TTCTTTGTGC CGCTGCACGA GTTCCATTTG ACGCCGCAGG ACGTGGATCA GATGGTCAGC 
AACGTGGCCT TCGCCTTCGA CCTGATGCAG GACGTGGGCC TGCCCAAACC AAAGGCGCGG 
CCGGAGGACA TCGTGAACAT GGACCTCAAG TCCACCCTGC GCGTCCTATA CAGCCTGTTC 
ACCATGTTCA GGGACTTCGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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parvin cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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