Hexo2 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	Hexo2
Entrez Gene ID	31808
Full Name	Hexosaminidase 2
Synonyms	CG1787,DmHex2,Dmel\CG1787,HEX 2,HEX2,HEXO2
General protein information	Preferred Names Hexosaminidase 2 Names CG1787 gene product from transcript CG1787-RA CG1787-PA Hexo2-PA hexosaminidase 2
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: X Map Location: 8A2-8A2

mRNA and Protein(s)

mRNA	Protein	Name
NM_080342.4	NP_525081.1	hexosaminidase 2

Pathways from BioSystems

Homologies

Drosophila melanogaster (fruit fly)	Hexo2	NP_525081.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP012453	XP_307483.4

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Beta-hexosaminidase is a peptidoglycan hydrolase that surprisingly exerts its mycobactericidal effect at the macrophage plasma membrane during mycobacteria-induced secretion of lysosomes
Title: Role for lysosomal enzyme beta-hexosaminidase in the control of mycobacteria infection.

purification and characterization of hexosaminidase 2 from spermatozoa plasma membrane
Title: Purification and characterization of the plasma membrane glycosidases of Drosophila melanogaster spermatozoa.

The following Hexo2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Hexo2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OFa03288	NM_080342.4 Latest version!	Drosophila melanogaster hexosaminidase 2 (Hexo2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Hexo2 ( NM_080342.4 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_525081.1 Drosophila melanogaster hexosaminidase 2 (Hexo2), mRNA.

Price & Availability↑

CloneID	OFa03288
Clone ID Related Accession (Same CDS sequence)	NM_080342.4
Accession Version	NM_080342.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1869bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	hexosaminidase 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NC_004354). On Jul 15, 2014 this sequence version replaced NM_080342.3. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGCGGTTCA GCGGCTACAA TCGTTATCAG TGCTTTTGCT CTGCTGTTGG ATCGCTGCTG 
CTATTATCCC TATTATCCTT CGCGGTCGGC GCTGCGCTGA CGCGGGCAGA TGACGTCGGC 
AGCGACGCCG ACGCCGGCAG CGCCAGCAGG AAATGGCTGT GCAGCCGGAC GGATATCTGC 
ACCGCGGAGG GCGAGATGGT GGCCGGACTG CAGTACGCGC CGGAGATCTT CGAGAGCCAG 
CGGGATTGCC GACTGTCGTG CGGCAAGTAC GGAGCCATCT GGCCCATGCC CACCGGCAAG 
GAGTGCACCA TATCGCACAG GCGGGTACGA TTCGATCCGT GGAAGGTGCG TTTCCATGTT 
GTGGCGCCCG GCGAGGCGGC CACCCAGTTT CTCAGGGAGA CGAACCGGCT GTTCGTCTCG 
AATCTGCTGA AGGAGTGCAT ACGAAACTGC ACGCTGGAGA CCAGCAAGCA GATTCTGGTC 
AGATCCACGG TGGCCAACGA GAGCCTCGTT CTGGACTGGC CCACCGACGA GAGCTACGCC 
CTGGTGGTGC GAACCACTGA AACGGCCACC TTTGTGGACA TCCAAGCGAC GACGGTGTAC 
GGTGCACGTC ATGCCTTCGA GACGCTGAGC AACCTGGTCA CCGGCAGCCT GTCCAATGGC 
CTGCTGATGG TCACCACGGC CAACATCACC GATCGTCCGG CCTTTTCGCA TCGCGGCGTC 
CTTCTGGATA CGGCCCGTAA CTTTGTGCCG CTCAAGTTTA TACGCAGCAC CTTGGATGCG 
ATGGCGGCCA GTAAGCTGAA TGTGCTCCAC TGGCATGTGG TGGACACGCA CAGTTTTCCG 
CTGGAGATCA CCAGGGTGCC GGAGATGCAG CGTTACGGAG CGTACTCCTC ATCGCAGACG 
TACTCGCGCC AGGATGCACT GAATCTTGTG AAATATGCCC GACTGCGGGG CATACGGATA 
CTGATCGAGA TCGATGGACC CTCGCATGCG GGCAATGGCT GGCAATGGGG TCCTGCCGCC 
GGACTGGGCA ACATGTCCGT GTGCCTGAAT CAATCGCCCT GGAGGAGATT CTGTGTACAG 
CCACCGTGCG GCCAACTGAA TCCCCTGAAC GATCATATGT ACGCAGTGCT CAAGGAGATC 
TTCGAGGACG TAGCCGAGGT GGGCGCTCCC GAGGAGACCC TGCACATGGG CGGCGACGAG 
GTGTTCCTTC CCTGCTGGAA TAACACCGAC GAGATTCGGG ATGGGATGCG GGCACGTGGC 
TACGATCTCA GCGAGCAGAG CTTCCTGCGG CTGTGGTCGC AATTCCATCA GCGGAACCTC 
AATGCATGGG ACGAGATTAA CGAGCGTATG TATCCGGGCA TCAAGGAGCC GAAGTCGGTG 
ATCATCTGGT CCAGTCACCT CACCAATCCC CGGTACATCG AGACCTACCT GCCCAAGGAG 
CGGTTCATAA TCCAGACATG GGTGGAGTCA CAGGATGCCC TCAATCGGGA GCTATTGCAG 
CGAGGCTACC GACTGATTGT GTCCACGAAG AATGCCTGGT ACCTGGATCA CGGCTTCTGG 
GGCAGCACAT CGTACTACAA CTGGCGCACC GTGTACTCCA GTGGCATGCC CGTTGGTCGC 
AGCAAGGATC AGGTTCTCGG CGGTGAGGTG TGCATGTGGA GCGAGTATGT GGATCAGAAC 
TCACTGGAAT CCCGAATCTG GCCGCGAGCT GGAGCAGCAG CCGAGCGAAT GTGGTCAAAT 
CCAAAGTCTT CAGCCCTGTT GGCCCAAAGA AGATTCTACC GCTACCGGGA GCGACTCCTG 
GCGCGCGGAA TCCATGCGGA TGCAGTTATT CCGCACTGGT GCGTCCTCCA CGAAGGACAG 
TGCCTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_525081.1
CDS	158..2026
Translation	MRFSGYNRYQCFCSAVGSLLLLSLLSFAVGAALTRADDVGSDADAGSASRKWLCSRTDICTAEGEMVAGLQYAPEIFESQRDCRLSCGKYGAIWPMPTGKECTISHRRVRFDPWKVRFHVVAPGEAATQFLRETNRLFVSNLLKECIRNCTLETSKQILVRSTVANESLVLDWPTDESYALVVRTTETATFVDIQATTVYGARHAFETLSNLVTGSLSNGLLMVTTANITDRPAFSHRGVLLDTARNFVPLKFIRSTLDAMAASKLNVLHWHVVDTHSFPLEITRVPEMQRYGAYSSSQTYSRQDALNLVKYARLRGIRILIEIDGPSHAGNGWQWGPAAGLGNMSVCLNQSPWRRFCVQPPCGQLNPLNDHMYAVLKEIFEDVAEVGAPEETLHMGGDEVFLPCWNNTDEIRDGMRARGYDLSEQSFLRLWSQFHQRNLNAWDEINERMYPGIKEPKSVIIWSSHLTNPRYIETYLPKERFIIQTWVESQDALNRELLQRGYRLIVSTKNAWYLDHGFWGSTSYYNWRTVYSSGMPVGRSKDQVLGGEVCMWSEYVDQNSLESRIWPRAGAAAERMWSNPKSSALLAQRRFYRYRERLLARGIHADAVIPHWCVLHEGQCL

Target ORF information:

RefSeq Version	NM_080342.4
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster hexosaminidase 2 (Hexo2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_080342.4

ORF Insert Sequence:

ATGCGGTTCA GCGGCTACAA TCGTTATCAG TGCTTTTGCT CTGCTGTTGG ATCGCTGCTG 
CTATTATCCC TATTATCCTT CGCGGTCGGC GCTGCGCTGA CGCGGGCAGA TGACGTCGGC 
AGCGACGCCG ACGCCGGCAG CGCCAGCAGG AAATGGCTGT GCAGCCGGAC GGATATCTGC 
ACCGCGGAGG GCGAGATGGT GGCCGGACTG CAGTACGCGC CGGAGATCTT CGAGAGCCAG 
CGGGATTGCC GACTGTCGTG CGGCAAGTAC GGAGCCATCT GGCCCATGCC CACCGGCAAG 
GAGTGCACCA TATCGCACAG GCGGGTACGA TTCGATCCGT GGAAGGTGCG TTTCCATGTT 
GTGGCGCCCG GCGAGGCGGC CACCCAGTTT CTCAGGGAGA CGAACCGGCT GTTCGTCTCG 
AATCTGCTGA AGGAGTGCAT ACGAAACTGC ACGCTGGAGA CCAGCAAGCA GATTCTGGTC 
AGATCCACGG TGGCCAACGA GAGCCTCGTT CTGGACTGGC CCACCGACGA GAGCTACGCC 
CTGGTGGTGC GAACCACTGA AACGGCCACC TTTGTGGACA TCCAAGCGAC GACGGTGTAC 
GGTGCACGTC ATGCCTTCGA GACGCTGAGC AACCTGGTCA CCGGCAGCCT GTCCAATGGC 
CTGCTGATGG TCACCACGGC CAACATCACC GATCGTCCGG CCTTTTCGCA TCGCGGCGTC 
CTTCTGGATA CGGCCCGTAA CTTTGTGCCG CTCAAGTTTA TACGCAGCAC CTTGGATGCG 
ATGGCGGCCA GTAAGCTGAA TGTGCTCCAC TGGCATGTGG TGGACACGCA CAGTTTTCCG 
CTGGAGATCA CCAGGGTGCC GGAGATGCAG CGTTACGGAG CGTACTCCTC ATCGCAGACG 
TACTCGCGCC AGGATGCACT GAATCTTGTG AAATATGCCC GACTGCGGGG CATACGGATA 
CTGATCGAGA TCGATGGACC CTCGCATGCG GGCAATGGCT GGCAATGGGG TCCTGCCGCC 
GGACTGGGCA ACATGTCCGT GTGCCTGAAT CAATCGCCCT GGAGGAGATT CTGTGTACAG 
CCACCGTGCG GCCAACTGAA TCCCCTGAAC GATCATATGT ACGCAGTGCT CAAGGAGATC 
TTCGAGGACG TAGCCGAGGT GGGCGCTCCC GAGGAGACCC TGCACATGGG CGGCGACGAG 
GTGTTCCTTC CCTGCTGGAA TAACACCGAC GAGATTCGGG ATGGGATGCG GGCACGTGGC 
TACGATCTCA GCGAGCAGAG CTTCCTGCGG CTGTGGTCGC AATTCCATCA GCGGAACCTC 
AATGCATGGG ACGAGATTAA CGAGCGTATG TATCCGGGCA TCAAGGAGCC GAAGTCGGTG 
ATCATCTGGT CCAGTCACCT CACCAATCCC CGGTACATCG AGACCTACCT GCCCAAGGAG 
CGGTTCATAA TCCAGACATG GGTGGAGTCA CAGGATGCCC TCAATCGGGA GCTATTGCAG 
CGAGGCTACC GACTGATTGT GTCCACGAAG AATGCCTGGT ACCTGGATCA CGGCTTCTGG 
GGCAGCACAT CGTACTACAA CTGGCGCACC GTGTACTCCA GTGGCATGCC CGTTGGTCGC 
AGCAAGGATC AGGTTCTCGG CGGTGAGGTG TGCATGTGGA GCGAGTATGT GGATCAGAAC 
TCACTGGAAT CCCGAATCTG GCCGCGAGCT GGAGCAGCAG CCGAGCGAAT GTGGTCAAAT 
CCAAAGTCTT CAGCCCTGTT GGCCCAAAGA AGATTCTACC GCTACCGGGA GCGACTCCTG 
GCGCGCGGAA TCCATGCGGA TGCAGTTATT CCGCACTGGT GCGTCCTCCA CGAAGGACAG 
TGCCTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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Hexo2 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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