XRCC1 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	XRCC1
Entrez Gene ID	31451
Full Name	CG4208 gene product from transcript CG4208-RA
Synonyms	4208,CG4208,Dmel\CG4208,Xrcc1
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: X Map Location: 4F5-4F5

mRNA and Protein(s)

mRNA	Protein	Name
NM_131989.4	NP_572217.1	XRCC1

Pathways from BioSystems

Homologies

Drosophila melanogaster (fruit fly)	XRCC1	NP_572217.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002605	XP_312330.5

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Fibrosis in radiotherapy-treated breast neoplasms tends to be higher in patients being polymorphic in XRCC1 when compared to patients with wildtype genotype.
Title: Association of single nucleotide polymorphisms in ATM, GSTP1, SOD2, TGFB1, XPD and XRCC1 with clinical and cellular radiosensitivity.

Individuals possessing more susceptible XRCC1 Gln-Gln genotypes were more likely to reveal p53 overexpression. Susceptible XRCC1 genotypes may modulate the mutation of the p53 gene among VCM-exposed workers.
Title: XRCC1 and CYP2E1 polymorphisms as susceptibility factors of plasma mutant p53 protein and anti-p53 antibody expression in vinyl chloride monomer-exposed polyvinyl chloride workers.

The following XRCC1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the XRCC1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OFa00847	NM_131989.4 Latest version!	Drosophila melanogaster XRCC1 (XRCC1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

XRCC1 ( NM_131989.4 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_572217.1 Drosophila melanogaster XRCC1 (XRCC1), mRNA.

Price & Availability↑

CloneID	OFa00847
Clone ID Related Accession (Same CDS sequence)	NM_131989.4
Accession Version	NM_131989.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1845bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	XRCC1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NC_004354). On Jul 15, 2014 this sequence version replaced NM_131989.3. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGCCAATTG CGCTTTTCAA GTCCGTACGC GAAGTGAGCA GCGAAGATGC GGTGCACGTA 
GCGGCGAATC TGCTCAAGGA AAACGCCGGC AAGAAGTGGC GAACCAAGGC GCCGGGAGAG 
AAATCCGCAT ACGTTGTGCT GGAGTTCGAG GAGCCGCAAC AGATTACGGG CATCGATATT 
GGCAACGAAC ATGCCGCCTT CATCGAGGTG CTGGTCAGTC GAACAGGCTG CCAGGCGGAC 
GATTTCCGCG AGCTGCTGCT ATCCAGTTCG TTTATGACGC CCATCGAGAG CAAGAATTCC 
AGCAATCCAA ATCGCGTTCG CTGTTTCAGT AGCACTTCGC TGGCGGAGAG TGCACTGCCG 
GAGAAGTGGA AGCTGCTTCA GATAGTCTGC ACACAGCCCT TCAATCGTCA TGTGCCATAC 
GGGCTCTCAT TCGTCAAGGT GCATGTAGTG GCTGCTGCGG CGCCTAAGGT CAAATCCCTA 
GTGCCGCAGG GTGTTATGCA ATTCGGGACC TTTAAGCTGC GCGAGGAGTC GCCGGACTCG 
GAAACGGACA ATCAAGTGAA CAGATTTCAC AGCTGGAAGA AGCAGACGCA GCACAAGTCG 
CCCGCGATCA GTGCGACCTC CACAGCAGCG GCCATTCGGG ACGCCGGCTC CACGGCCCTG 
CGAAGGCTGA GCGCTGGCAA GGTTTCTAGC CTGGCTGCAT CGCCCAAAAC CTCGACGTCG 
CCATCACCAG TTCTCAATGC TCTGCGATCG GTTTCTCCGA CGCCATTGGA TGCCAAGCCC 
CTGGATCGCA ATCGAGCTTC ACTCTTGTTC GGCGACGATG ATGAGGACGT GAAGGACGCT 
GAGGTCAATG CAAAGAAACA ACGGCTGAGC AAGCATCTGG AGGCGGACAA GGATCGACGG 
CGATTGGAGC AGGAAAAGGA GAGGGAGAGC AGAAAGAAAA AGTCAAGCAG GCACTCCTTG 
GATAAGTCAA TCAGCAAAGA AGACAAACCA CCGGCAAAGG AGCACAATTC GTCCTCCAGA 
GAAAAATCCA CAGCCAAAGA AGAGAAAGAG CAATTACGAA AAGAGGAAAG ATCGCATTCG 
AAGGAGGAGA AGTCCAGGAG GAAGGAGAAA TCTAAGCATG ATCACAGATC TTCGGACACC 
TCGAATTCCA AGGAAAGTTC GCGCCCAACT GCGCAAAAGC GACATTCATC TCCCACCGCA 
GTCGCAGTAA CGCCCGCCAA AAAGCAAAAG ATCGTGGACA CAGCGATTCA ATACCGTCCC 
CTTAATCAGT TACTCAAGGG TGTGGTCCTG GTCATCAGTG GCATACAGAA TCCCGATCGT 
GCAGACTTGC GTTCGAAAGC GGTCGCCTTG GGAGCCAAGT ATAAGGCTGA TTGGGGATCA 
GGATGTACCC ATCTGATATG CGCATTCAAA AACACACCGA AATACAATCA AGTGAAGGGC 
AAGGGCAAGA TTGTGACACG CAGTTGGATC GAGAAATGTT ATGAGCTGAA GAAGTACCTG 
CCATGGCGAC GTTACGCCCT GGATACCAAT GACATTGGCC AGCCGGAGAG CGATGAGGAG 
CTTTGCGATG AGGCGACGAG GCCACGGCGC GATTCCAGCA AGGATGATGT GGCAATGCTA 
GAGGATAGCA AGCTAACAGC TCTAGCGGAT CAGAATGATG TGGAAATGAA TCCAGATGCC 
TTATCGGGCA TTGATACGGA AGATGAACTG CAGCGCGTGG CTGAGGAAAA CAAAACGAAG 
AAAGCCAAAC TAAGGACTAC AGTAAAGACG AAATCGCAAG ATATATACGA AGTTAGTACC 
GATGAAGAGG ATTATCTGGA GCTAAAGAAG AAACAAATCG ATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_572217.1
CDS	227..2071
Translation	MPIALFKSVREVSSEDAVHVAANLLKENAGKKWRTKAPGEKSAYVVLEFEEPQQITGIDIGNEHAAFIEVLVSRTGCQADDFRELLLSSSFMTPIESKNSSNPNRVRCFSSTSLAESALPEKWKLLQIVCTQPFNRHVPYGLSFVKVHVVAAAAPKVKSLVPQGVMQFGTFKLREESPDSETDNQVNRFHSWKKQTQHKSPAISATSTAAAIRDAGSTALRRLSAGKVSSLAASPKTSTSPSPVLNALRSVSPTPLDAKPLDRNRASLLFGDDDEDVKDAEVNAKKQRLSKHLEADKDRRRLEQEKERESRKKKSSRHSLDKSISKEDKPPAKEHNSSSREKSTAKEEKEQLRKEERSHSKEEKSRRKEKSKHDHRSSDTSNSKESSRPTAQKRHSSPTAVAVTPAKKQKIVDTAIQYRPLNQLLKGVVLVISGIQNPDRADLRSKAVALGAKYKADWGSGCTHLICAFKNTPKYNQVKGKGKIVTRSWIEKCYELKKYLPWRRYALDTNDIGQPESDEELCDEATRPRRDSSKDDVAMLEDSKLTALADQNDVEMNPDALSGIDTEDELQRVAEENKTKKAKLRTTVKTKSQDIYEVSTDEEDYLELKKKQID

Target ORF information:

RefSeq Version	NM_131989.4
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster XRCC1 (XRCC1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_131989.4

ORF Insert Sequence:

ATGCCAATTG CGCTTTTCAA GTCCGTACGC GAAGTGAGCA GCGAAGATGC GGTGCACGTA 
GCGGCGAATC TGCTCAAGGA AAACGCCGGC AAGAAGTGGC GAACCAAGGC GCCGGGAGAG 
AAATCCGCAT ACGTTGTGCT GGAGTTCGAG GAGCCGCAAC AGATTACGGG CATCGATATT 
GGCAACGAAC ATGCCGCCTT CATCGAGGTG CTGGTCAGTC GAACAGGCTG CCAGGCGGAC 
GATTTCCGCG AGCTGCTGCT ATCCAGTTCG TTTATGACGC CCATCGAGAG CAAGAATTCC 
AGCAATCCAA ATCGCGTTCG CTGTTTCAGT AGCACTTCGC TGGCGGAGAG TGCACTGCCG 
GAGAAGTGGA AGCTGCTTCA GATAGTCTGC ACACAGCCCT TCAATCGTCA TGTGCCATAC 
GGGCTCTCAT TCGTCAAGGT GCATGTAGTG GCTGCTGCGG CGCCTAAGGT CAAATCCCTA 
GTGCCGCAGG GTGTTATGCA ATTCGGGACC TTTAAGCTGC GCGAGGAGTC GCCGGACTCG 
GAAACGGACA ATCAAGTGAA CAGATTTCAC AGCTGGAAGA AGCAGACGCA GCACAAGTCG 
CCCGCGATCA GTGCGACCTC CACAGCAGCG GCCATTCGGG ACGCCGGCTC CACGGCCCTG 
CGAAGGCTGA GCGCTGGCAA GGTTTCTAGC CTGGCTGCAT CGCCCAAAAC CTCGACGTCG 
CCATCACCAG TTCTCAATGC TCTGCGATCG GTTTCTCCGA CGCCATTGGA TGCCAAGCCC 
CTGGATCGCA ATCGAGCTTC ACTCTTGTTC GGCGACGATG ATGAGGACGT GAAGGACGCT 
GAGGTCAATG CAAAGAAACA ACGGCTGAGC AAGCATCTGG AGGCGGACAA GGATCGACGG 
CGATTGGAGC AGGAAAAGGA GAGGGAGAGC AGAAAGAAAA AGTCAAGCAG GCACTCCTTG 
GATAAGTCAA TCAGCAAAGA AGACAAACCA CCGGCAAAGG AGCACAATTC GTCCTCCAGA 
GAAAAATCCA CAGCCAAAGA AGAGAAAGAG CAATTACGAA AAGAGGAAAG ATCGCATTCG 
AAGGAGGAGA AGTCCAGGAG GAAGGAGAAA TCTAAGCATG ATCACAGATC TTCGGACACC 
TCGAATTCCA AGGAAAGTTC GCGCCCAACT GCGCAAAAGC GACATTCATC TCCCACCGCA 
GTCGCAGTAA CGCCCGCCAA AAAGCAAAAG ATCGTGGACA CAGCGATTCA ATACCGTCCC 
CTTAATCAGT TACTCAAGGG TGTGGTCCTG GTCATCAGTG GCATACAGAA TCCCGATCGT 
GCAGACTTGC GTTCGAAAGC GGTCGCCTTG GGAGCCAAGT ATAAGGCTGA TTGGGGATCA 
GGATGTACCC ATCTGATATG CGCATTCAAA AACACACCGA AATACAATCA AGTGAAGGGC 
AAGGGCAAGA TTGTGACACG CAGTTGGATC GAGAAATGTT ATGAGCTGAA GAAGTACCTG 
CCATGGCGAC GTTACGCCCT GGATACCAAT GACATTGGCC AGCCGGAGAG CGATGAGGAG 
CTTTGCGATG AGGCGACGAG GCCACGGCGC GATTCCAGCA AGGATGATGT GGCAATGCTA 
GAGGATAGCA AGCTAACAGC TCTAGCGGAT CAGAATGATG TGGAAATGAA TCCAGATGCC 
TTATCGGGCA TTGATACGGA AGATGAACTG CAGCGCGTGG CTGAGGAAAA CAAAACGAAG 
AAAGCCAAAC TAAGGACTAC AGTAAAGACG AAATCGCAAG ATATATACGA AGTTAGTACC 
GATGAAGAGG ATTATCTGGA GCTAAAGAAG AAACAAATCG ATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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XRCC1 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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