Torsin cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	Torsin
Entrez Gene ID	31399
Full Name	CG3024 gene product from transcript CG3024-RB
Synonyms	CG3024,DTor,DmTorp4a,Dmel\CG3024,EG:84H4.1,TORP4A,Torp4a,dtor,dtorsin,torp4a,torsin
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: X Map Location: 4C11-4C11

mRNA and Protein(s)

mRNA	Protein	Name
NM_131950.4	NP_572178.1	torsin, isoform A
NM_001297937.1	NP_001284866.1	torsin, isoform B

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Tor1a	NP_659133.1
Drosophila melanogaster (fruit fly)	Torsin	NP_572178.1
Xenopus tropicalis (tropical clawed frog)	tor1b	NP_001016237.1
Homo sapiens (human)	TOR1A	NP_000104.1
Pan troglodytes (chimpanzee)	TOR1A	XP_001164380.2
Canis lupus familiaris (dog)	TOR1A	XP_548417.3
Bos taurus (cattle)	TOR1A	NP_001092528.1
Rattus norvegicus (Norway rat)	Tor1a	NP_695215.2
Gallus gallus (chicken)	TOR1A	NP_001025858.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP009547	XP_310142.4

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The dtorsin mutant showed a very strong genetic interaction with Pu (Punch: GTP cyclohydrolase), the ortholog of the human gene underlying DYT14 dystonia.
Title: Dtorsin, the Drosophila ortholog of the early-onset dystonia TOR1A (DYT1), plays a novel role in dopamine metabolism.

The following Torsin gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Torsin cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OFa00795	NM_001297937.1 Latest version!	Drosophila melanogaster torsin, transcript variant B (Torsin), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00
OFa00795	NM_131950.4 Latest version!	Drosophila melanogaster torsin, transcript variant A (Torsin), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Torsin ( NM_131950.4 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_572178.1 Drosophila melanogaster torsin, transcript variant A (Torsin), mRNA.

Price & Availability↑

CloneID	OFa00795
Clone ID Related Accession (Same CDS sequence)	NM_131950.4 , NM_001297937.1
Accession Version	NM_131950.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1023bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	torsin, isoform A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NC_004354). On Jul 15, 2014 this sequence version replaced NM_131950.3. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGATGAGCT TTCCACGCAT GTTATCACTG TGCCTTAGCG TGCTTGTAAT ACTGCCGCTT 
CCCCTCCAGT CGGTGGATCC CCTGACCATT GGTGCCGTTG GCGCCGTGGC CCTTGGGGCG 
TACTTCAAAG AACATACATA TTGCCGGTTT GCCGAATGCT GCGATGACCG AAACATTCCG 
GCGAGAATAG ATGAATTAGA AAGATCCCTG GAACGCACCC TCATTGGCCA GCACATCGTG 
AGGCAGCATA TCGTCCCCGC ACTGAAGGCG CACATCGCTT CGGGCAATAA GTCACGGAAA 
CCGCTGGTCA TCAGCTTTCA CGGCCAGCCC GGTACGGGCA AGAATTTTGT GGCTGAGCAA 
ATTGCAGATG CTATGTATTT GAAGGGCTCC AGGTCGAACT ATGTAACCAA GTATCTCGGA 
CAAGCTGACT TTCCCAAGGA AAGTGAGGTG TCTAACTATA GGGTGAAAAT CAATAATGCG 
GTGCGCGATA CCTTGCGTAG CTGCCCGAGA TCTTTGTTCA TCTTCGACGA GGTGGATAAA 
ATGCCCAGCG GAGTATTCGA CCAGCTCACC TCGCTGGTGG ACTACAACGC CTTTGTCGAT 
GGCACGGATA ACACAAAGGC AATCTTCATC TTTCTCTCGA ACACGGCGGG CAGTCATATA 
GCCAGTCATC TGGGTAGTGT GATGAAGAAT GGTAGGCTGC GCGAGGACAC ACGACTGAGT 
GACTTTGAGC CCCTTTTGCG GAAGGCCGCC TATAACATGG ATGGCGGTAT GAAAAAGACC 
ACCATGATTG AGTCTCATGT TATCGATCAT TTCATTCCGT TCCTGCCGAT GGAGAAGGCG 
CATGTGATCA AGTGCCTGGA GGCGGAGCTT TTAAGGTGGC GGCGCGATCC TAAGCAAGCG 
AACAACCAAA AAATCATTGA GGACATAATA AACTCCTCCA TTAGTTACGA TCGCACGCAC 
AGCTTGTTCG CCATTTCGGG CTGCAAGACG CTGGAGAAGA AGGTGGCCAT GGCCATTTAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_572178.1
CDS	69..1091
Translation	MMSFPRMLSLCLSVLVILPLPLQSVDPLTIGAVGAVALGAYFKEHTYCRFAECCDDRNIPARIDELERSLERTLIGQHIVRQHIVPALKAHIASGNKSRKPLVISFHGQPGTGKNFVAEQIADAMYLKGSRSNYVTKYLGQADFPKESEVSNYRVKINNAVRDTLRSCPRSLFIFDEVDKMPSGVFDQLTSLVDYNAFVDGTDNTKAIFIFLSNTAGSHIASHLGSVMKNGRLREDTRLSDFEPLLRKAAYNMDGGMKKTTMIESHVIDHFIPFLPMEKAHVIKCLEAELLRWRRDPKQANNQKIIEDIINSSISYDRTHSLFAISGCKTLEKKVAMAIY

Target ORF information:

RefSeq Version	NM_131950.4
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster torsin, transcript variant A (Torsin), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_131950.4

ORF Insert Sequence:

ATGATGAGCT TTCCACGCAT GTTATCACTG TGCCTTAGCG TGCTTGTAAT ACTGCCGCTT 
CCCCTCCAGT CGGTGGATCC CCTGACCATT GGTGCCGTTG GCGCCGTGGC CCTTGGGGCG 
TACTTCAAAG AACATACATA TTGCCGGTTT GCCGAATGCT GCGATGACCG AAACATTCCG 
GCGAGAATAG ATGAATTAGA AAGATCCCTG GAACGCACCC TCATTGGCCA GCACATCGTG 
AGGCAGCATA TCGTCCCCGC ACTGAAGGCG CACATCGCTT CGGGCAATAA GTCACGGAAA 
CCGCTGGTCA TCAGCTTTCA CGGCCAGCCC GGTACGGGCA AGAATTTTGT GGCTGAGCAA 
ATTGCAGATG CTATGTATTT GAAGGGCTCC AGGTCGAACT ATGTAACCAA GTATCTCGGA 
CAAGCTGACT TTCCCAAGGA AAGTGAGGTG TCTAACTATA GGGTGAAAAT CAATAATGCG 
GTGCGCGATA CCTTGCGTAG CTGCCCGAGA TCTTTGTTCA TCTTCGACGA GGTGGATAAA 
ATGCCCAGCG GAGTATTCGA CCAGCTCACC TCGCTGGTGG ACTACAACGC CTTTGTCGAT 
GGCACGGATA ACACAAAGGC AATCTTCATC TTTCTCTCGA ACACGGCGGG CAGTCATATA 
GCCAGTCATC TGGGTAGTGT GATGAAGAAT GGTAGGCTGC GCGAGGACAC ACGACTGAGT 
GACTTTGAGC CCCTTTTGCG GAAGGCCGCC TATAACATGG ATGGCGGTAT GAAAAAGACC 
ACCATGATTG AGTCTCATGT TATCGATCAT TTCATTCCGT TCCTGCCGAT GGAGAAGGCG 
CATGTGATCA AGTGCCTGGA GGCGGAGCTT TTAAGGTGGC GGCGCGATCC TAAGCAAGCG 
AACAACCAAA AAATCATTGA GGACATAATA AACTCCTCCA TTAGTTACGA TCGCACGCAC 
AGCTTGTTCG CCATTTCGGG CTGCAAGACG CTGGAGAAGA AGGTGGCCAT GGCCATTTAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Torsin ( NM_001297937.1 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_001284866.1 Drosophila melanogaster torsin, transcript variant B (Torsin), mRNA.

Price & Availability↑

CloneID	OFa00795
Clone ID Related Accession (Same CDS sequence)	NM_131950.4 , NM_001297937.1
Accession Version	NM_001297937.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1023bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	torsin, isoform B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NC_004354). ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGATGAGCT TTCCACGCAT GTTATCACTG TGCCTTAGCG TGCTTGTAAT ACTGCCGCTT 
CCCCTCCAGT CGGTGGATCC CCTGACCATT GGTGCCGTTG GCGCCGTGGC CCTTGGGGCG 
TACTTCAAAG AACATACATA TTGCCGGTTT GCCGAATGCT GCGATGACCG AAACATTCCG 
GCGAGAATAG ATGAATTAGA AAGATCCCTG GAACGCACCC TCATTGGCCA GCACATCGTG 
AGGCAGCATA TCGTCCCCGC ACTGAAGGCG CACATCGCTT CGGGCAATAA GTCACGGAAA 
CCGCTGGTCA TCAGCTTTCA CGGCCAGCCC GGTACGGGCA AGAATTTTGT GGCTGAGCAA 
ATTGCAGATG CTATGTATTT GAAGGGCTCC AGGTCGAACT ATGTAACCAA GTATCTCGGA 
CAAGCTGACT TTCCCAAGGA AAGTGAGGTG TCTAACTATA GGGTGAAAAT CAATAATGCG 
GTGCGCGATA CCTTGCGTAG CTGCCCGAGA TCTTTGTTCA TCTTCGACGA GGTGGATAAA 
ATGCCCAGCG GAGTATTCGA CCAGCTCACC TCGCTGGTGG ACTACAACGC CTTTGTCGAT 
GGCACGGATA ACACAAAGGC AATCTTCATC TTTCTCTCGA ACACGGCGGG CAGTCATATA 
GCCAGTCATC TGGGTAGTGT GATGAAGAAT GGTAGGCTGC GCGAGGACAC ACGACTGAGT 
GACTTTGAGC CCCTTTTGCG GAAGGCCGCC TATAACATGG ATGGCGGTAT GAAAAAGACC 
ACCATGATTG AGTCTCATGT TATCGATCAT TTCATTCCGT TCCTGCCGAT GGAGAAGGCG 
CATGTGATCA AGTGCCTGGA GGCGGAGCTT TTAAGGTGGC GGCGCGATCC TAAGCAAGCG 
AACAACCAAA AAATCATTGA GGACATAATA AACTCCTCCA TTAGTTACGA TCGCACGCAC 
AGCTTGTTCG CCATTTCGGG CTGCAAGACG CTGGAGAAGA AGGTGGCCAT GGCCATTTAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001284866.1
CDS	268..1290
Translation	MMSFPRMLSLCLSVLVILPLPLQSVDPLTIGAVGAVALGAYFKEHTYCRFAECCDDRNIPARIDELERSLERTLIGQHIVRQHIVPALKAHIASGNKSRKPLVISFHGQPGTGKNFVAEQIADAMYLKGSRSNYVTKYLGQADFPKESEVSNYRVKINNAVRDTLRSCPRSLFIFDEVDKMPSGVFDQLTSLVDYNAFVDGTDNTKAIFIFLSNTAGSHIASHLGSVMKNGRLREDTRLSDFEPLLRKAAYNMDGGMKKTTMIESHVIDHFIPFLPMEKAHVIKCLEAELLRWRRDPKQANNQKIIEDIINSSISYDRTHSLFAISGCKTLEKKVAMAIY

Target ORF information:

RefSeq Version	NM_001297937.1
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster torsin, transcript variant B (Torsin), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001297937.1

ORF Insert Sequence:

ATGATGAGCT TTCCACGCAT GTTATCACTG TGCCTTAGCG TGCTTGTAAT ACTGCCGCTT 
CCCCTCCAGT CGGTGGATCC CCTGACCATT GGTGCCGTTG GCGCCGTGGC CCTTGGGGCG 
TACTTCAAAG AACATACATA TTGCCGGTTT GCCGAATGCT GCGATGACCG AAACATTCCG 
GCGAGAATAG ATGAATTAGA AAGATCCCTG GAACGCACCC TCATTGGCCA GCACATCGTG 
AGGCAGCATA TCGTCCCCGC ACTGAAGGCG CACATCGCTT CGGGCAATAA GTCACGGAAA 
CCGCTGGTCA TCAGCTTTCA CGGCCAGCCC GGTACGGGCA AGAATTTTGT GGCTGAGCAA 
ATTGCAGATG CTATGTATTT GAAGGGCTCC AGGTCGAACT ATGTAACCAA GTATCTCGGA 
CAAGCTGACT TTCCCAAGGA AAGTGAGGTG TCTAACTATA GGGTGAAAAT CAATAATGCG 
GTGCGCGATA CCTTGCGTAG CTGCCCGAGA TCTTTGTTCA TCTTCGACGA GGTGGATAAA 
ATGCCCAGCG GAGTATTCGA CCAGCTCACC TCGCTGGTGG ACTACAACGC CTTTGTCGAT 
GGCACGGATA ACACAAAGGC AATCTTCATC TTTCTCTCGA ACACGGCGGG CAGTCATATA 
GCCAGTCATC TGGGTAGTGT GATGAAGAAT GGTAGGCTGC GCGAGGACAC ACGACTGAGT 
GACTTTGAGC CCCTTTTGCG GAAGGCCGCC TATAACATGG ATGGCGGTAT GAAAAAGACC 
ACCATGATTG AGTCTCATGT TATCGATCAT TTCATTCCGT TCCTGCCGAT GGAGAAGGCG 
CATGTGATCA AGTGCCTGGA GGCGGAGCTT TTAAGGTGGC GGCGCGATCC TAAGCAAGCG 
AACAACCAAA AAATCATTGA GGACATAATA AACTCCTCCA TTAGTTACGA TCGCACGCAC 
AGCTTGTTCG CCATTTCGGG CTGCAAGACG CTGGAGAAGA AGGTGGCCAT GGCCATTTAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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Torsin cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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