llgl2 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	llgl2
Entrez Gene ID	795670
Full Name	lethal giant larvae homolog 2 (Drosophila)
Synonyms	cb521,lgl2,llglh2,sb:cb521,wu:fc06g08,wu:fl37c09,zgc:55895
General protein information	Preferred Names lethal giant larvae homolog 2 (Drosophila) Names lethal(2) giant larvae protein homolog 2 pen penner protein penner
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
XM_021480170.1	XP_021335845.1	lethal(2) giant larvae protein homolog 2 isoform X1
NM_212582.1	NP_997747.1	LLGL scribble cell polarity complex component 2

Pathways from BioSystems

Homologies

Homo sapiens (human)	LLGL2	NP_001026973.1
Bos taurus (cattle)	LLGL2	NP_001092568.1
Mus musculus (house mouse)	Llgl2	NP_663413.2
Danio rerio (zebrafish)	llgl2	NP_997747.1
Pan troglodytes (chimpanzee)	LLGL2	XP_523719.3
Canis lupus familiaris (dog)	LLGL2	XP_005624156.1
Gallus gallus (chicken)	LLGL2	XP_420130.3
Xenopus tropicalis (tropical clawed frog)	llgl2	NP_001015691.1
Rattus norvegicus (Norway rat)	Llgl2	NP_001121021.1

Gene Ontology
Bibliography

Related articles in PubMed

Evolution of complexity in the zebrafish synapse proteome.
Bay?s ?, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG
Nature communications814613(2017 Mar)

aPKC regulates apical localization of Lgl to restrict elongation of microridges in developing zebrafish epidermis.
Raman R, Damle I, Rote R, Banerjee S, Dingare C, Sonawane M
Nature communications711643(2016 Jun)

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y, Bobe J
BMC genomics17368(2016 05)

Tumor suppression in basal keratinocytes via dual non-cell-autonomous functions of a Na,K-ATPase beta subunit.
Hatzold J, Beleggia F, Herzig H, Altm?ller J, N?rnberg P, Bloch W, Wollnik B, Hammerschmidt M
eLife5(2016 05)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

New roles and interactions for Lgl2 that are crucial for both lumenogenesis and ciliogenesis and indicate that these processes are genetically separable in zebrafish.
Title: Lethal giant larvae 2 regulates development of the ciliated organ Kupffer's vesicle.

Lgl2 and E-cadherin act antagonistically to control the localisation of integrin alpha 6 during the formation of hemidesmosomes in the developing epidermis
Title: Lgl2 and E-cadherin act antagonistically to regulate hemidesmosome formation during epidermal development in zebrafish.

lgl2 is necessary for hemidesmosome formation and maintenance of the tissue integrity in the developing basal epidermis
Title: Zebrafish penner/lethal giant larvae 2 functions in hemidesmosome formation, maintenance of cellular morphology and growth regulation in the developing basal epidermis.

The following llgl2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the llgl2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa47006	XM_021480170.1 Latest version!	Danio rerio lethal giant larvae homolog 2 (Drosophila) (llgl2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$629.30 $899.00
ODa01122	NM_212582.1 Latest version!	Danio rerio LLGL scribble cell polarity complex component 2 (llgl2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$629.30 $899.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

llgl2 ( XM_021480170.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> XP_021335845.1 Danio rerio lethal giant larvae homolog 2 (Drosophila) (llgl2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ODa47006
Clone ID Related Accession (Same CDS sequence)	XM_021480170.1
Accession Version	XM_021480170.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3015bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-06-14
Organism	Danio rerio(zebrafish)
Product	lethal(2) giant larvae protein homolog 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_007123.7) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Danio rerio Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGAGGT TCAGGCGTCA TGGGCACGAG TCTCAGAGGG ACAAGCACAA ACAGGATCTC 
TATCAGTTCA ACAAGACTGT AGAGCATGGC TTCCCCCATC AACCCAGCGC TCTGGGATTC 
AGCCCTAGCC TGGAGCTCCT GGCCATCGGC ACCAGATCAG GAGCAATCAA ACTCTACGGA 
GCTCCAGGTG TGGAGTTCAT GGGGCTTCAC GACGAGAATG CGGCGGTTAC ACAGGTGCAC 
TTCCTGCCAA ACCAGGTGGA GTTGGTCACA TTACTAGAAG ACAACAGTCT ACATATGTGG 
ACACTTCGGG CTCATAACAG CATGTGTGAG CTGCTTGAGA TCGGACGGTT CACTCTCTCT 
GGTCCACCTG GTGCCATTCC CAGCGTGACG CGGGTCACTG CGGTCTTGGC ACACTCATCG 
GGTGAGCTGC TGCTGCTGGG CACAGAAGGA GGACACGTGT TTGTTGTGGA AGTGCCAGGA 
TTCAGAGAAC TGGAGGAGAA CAACATCAGC GTGGAGGACG TACAAAACAG AGTTCCAGAG 
GATTATGTTG GCCGCAGAAA TCTGGAGAGT GTTGAGACTC TTCATGAAAA CCCGCTGAAC 
CCGCGGCAAG TGCTGATTGG CTACAGCCGA GGCCTGATGG TTCTGTGGGA TCTGGACCGG 
CAGCGTCCCG TCCAGCACTT TCTGGGCACA CAGCAACTAG AGAGTGTTTG GTGGATGGAG 
GACGGTGAAA GCATTCTCAG TTCGCACAGT GATGGAAGCT ACTGCCAGTG GACGGTGACC 
GGTGAGGATC CGCAAACAGA GCCAGAGAAG CAGGAGACGC CGTATGGTGC CTTCCCATGC 
AAGGCTATAT CCAAAATTAT ACAGTTGCCA TCAAAACAAG GTCCCCCATT CCTCATCTTC 
AGTGGAGGGA TGCCGAGGGC CAGTTATGGG GACAGACACT GCATTTCTGT CATTCACAGC 
AAAACCCATG AAGCGCTGGA CTTCACCTCT CGCATTATTG ACTTCTTCGT CATTCGTGAA 
GGAGAAAACC ATAAAGGTGA ACCCAGCGCT CTTGTGGTTC TTGTGGAGGA GGAGCTGGTT 
GTGGTGGATC TGCAGACTGA AGGGTGGCCC GTCATCCAGA CGCCATACCT GGTGCCATTA 
CACTGTTCAG CCATCACTTG CTCACACCAC GTCTCCTCCA TCCCTCTCAA ACTGTGGGAG 
AGAGTGCAAG CTGCGGGAGC CCACCAGAAC ACACACTACT CCAGGAAGCC TTGGCCTATA 
AACGGAGGCA AGAATCTGGC CCCAGACCCT CCTCAGAGAG ACCTTCTCCT GACGGGACAT 
GAAGATGGAA CGGTGCGATT CTGGGACGCC TCAGGGGTCT GTCTTTACCC CATGTACAAG 
CTCAGCACAG CAGGAGTCTT CCACACGGAC GCCGATCCAA ACGACAACAT GAACCAGGGC 
AGTGAAGGAG AGTGGCCTCC ATTCCGAAAG GTTGGCTGCT TTGACCCATA TAGCGATGAC 
CCTCGGCTGG GTATTCAGAA GATCCACCTG TGTAAATACA GTGGATATCT CACAGTGGCC 
GGAACTGCAG GACAAATTCT GGTTCTGGAG CTGAATGATG AGGCTGCGGA GCAGATGGTA 
GAAGCTACGG TAGTGGACCT GCTGCAAGGT CAGGAGGGTT TCCGCTGGAA GGGACAGGCG 
CGTCTAGACG TTCGGGAGGA GCCGGTACTG TTTCCTCCAG GCTTTCAGCC ATTCGCCCTG 
GTGCAGTGCC AGCCACCCGC TGTGGTCACC GCAATCGCTC TGCACTCCGA GTGGAAACTA 
GTGGGCTTCG GGACCAGCCA TGGCTTTGGT CTTTATGATT ATAACCAGAG GAATAACATC 
ATGGTCAAAT GCACCCTTAA CCCCAGTGAC CAGATGGCTA TGGAGGGGCC GCTTTCACGA 
GTCAAGTCCA TCAAAAAGTC TCTGCGACAG TCCTTCCGCA GGATTCGCCG CAGTCGAGTC 
TCCATGCGCA AACACCACAC TAACAACGCA GCCAAGCTGC AGGAGATCAA TGCCAGGCTG 
GAGGCTGAGG CTCTGCAGGA GATGGAGCTG GCTCCTGTAC AGAGAAAGAT TGAAGCCCGA 
TCATCTGATG ACTCCTTCAC AGGTCTCGTC AGAACGCTCT ACTTCGCAGA TACATTTGTC 
AGTGATAGTT CTCACAGTAC ACCTTCACTG TGGGCAGGGA CCAATGGCGG AGCTGTGTTT 
GCATATGTCC TCCGTGTCCC ACCACAGGAA CGAAGGGCAG AGGATCCAGT GACGGCTCAT 
GCAGCCAAAG AGATTCAGTT GATGCATCGT GCTCCAGTTG TCGGTTTGGT GGTCTTGGAT 
GGGAAGGGAG CCCCTCTGCC CGAACCCCTA GAAGTGGCAC ATGACCTGGC ACGCAGTCCT 
GAAATGCATG GCTCACACCA TCTATTGGTT GTGTCAGAGG AGCAATTTAA GCTTTTTACA 
TTGCCCAAAG TGAGCAGTAA GTCGAAGCTA AAGCTGACGG CGGTGGATGG CTCTCGTGTG 
CGGCGTGTCG GTGTGGCTTG GTTTGGTTCT CGGACCGATG AACAGTTAGA GAGCTGTCTG 
GTGGTGCTGA CGAATCAGGG GGAGCTCCAC GTCATCTCTC TGCCCTCCAT CAAAATGCTG 
GTCCATTATC CTTGCATACG GAGAGAAGAC GTCAGTGGAA TCGCATCCTG TGTCTTCACC 
AAATATGGCC AAGGTTTCTA CCTGATCTCT CCATCCGAGT TTGAGCGGTT TTCTCTCTCC 
ACCCGTTGGG TCGTGCAACC TCACTGTCTG GTTGAGCCTC CCCTCCAGAT GAGGTCCAAG 
AGCCCATCAA GCCCTGTTCA CAGGGACTTG CCGGATGGAG TACCCACCGA ACACAGAAAT 
TTCAAAGGGG ACAGTGAAGG ATATGGTGTT CTGCAGGAGA TCCAGAAGTC TCTAGAAGGA 
GATCAAACGA CGTTCCTAGA GAACAATCTG AAGACTAAGC CTAAAGCAGG CAATGTGCTG 
AGCAATGGAG ATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_021335845.1
CDS	284..3298
Translation	MKRFRRHGHESQRDKHKQDLYQFNKTVEHGFPHQPSALGFSPSLELLAIGTRSGAIKLYGAPGVEFMGLHDENAAVTQVHFLPNQVELVTLLEDNSLHMWTLRAHNSMCELLEIGRFTLSGPPGAIPSVTRVTAVLAHSSGELLLLGTEGGHVFVVEVPGFRELEENNISVEDVQNRVPEDYVGRRNLESVETLHENPLNPRQVLIGYSRGLMVLWDLDRQRPVQHFLGTQQLESVWWMEDGESILSSHSDGSYCQWTVTGEDPQTEPEKQETPYGAFPCKAISKIIQLPSKQGPPFLIFSGGMPRASYGDRHCISVIHSKTHEALDFTSRIIDFFVIREGENHKGEPSALVVLVEEELVVVDLQTEGWPVIQTPYLVPLHCSAITCSHHVSSIPLKLWERVQAAGAHQNTHYSRKPWPINGGKNLAPDPPQRDLLLTGHEDGTVRFWDASGVCLYPMYKLSTAGVFHTDADPNDNMNQGSEGEWPPFRKVGCFDPYSDDPRLGIQKIHLCKYSGYLTVAGTAGQILVLELNDEAAEQMVEATVVDLLQGQEGFRWKGQARLDVREEPVLFPPGFQPFALVQCQPPAVVTAIALHSEWKLVGFGTSHGFGLYDYNQRNNIMVKCTLNPSDQMAMEGPLSRVKSIKKSLRQSFRRIRRSRVSMRKHHTNNAAKLQEINARLEAEALQEMELAPVQRKIEARSSDDSFTGLVRTLYFADTFVSDSSHSTPSLWAGTNGGAVFAYVLRVPPQERRAEDPVTAHAAKEIQLMHRAPVVGLVVLDGKGAPLPEPLEVAHDLARSPEMHGSHHLLVVSEEQFKLFTLPKVSSKSKLKLTAVDGSRVRRVGVAWFGSRTDEQLESCLVVLTNQGELHVISLPSIKMLVHYPCIRREDVSGIASCVFTKYGQGFYLISPSEFERFSLSTRWVVQPHCLVEPPLQMRSKSPSSPVHRDLPDGVPTEHRNFKGDSEGYGVLQEIQKSLEGDQTTFLENNLKTKPKAGNVLSNGD

Target ORF information:

RefSeq Version	XM_021480170.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio lethal giant larvae homolog 2 (Drosophila) (llgl2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_021480170.1

ORF Insert Sequence:

ATGAAGAGGT TCAGGCGTCA TGGGCACGAG TCTCAGAGGG ACAAGCACAA ACAGGATCTC 
TATCAGTTCA ACAAGACTGT AGAGCATGGC TTCCCCCATC AACCCAGCGC TCTGGGATTC 
AGCCCTAGCC TGGAGCTCCT GGCCATCGGC ACCAGATCAG GAGCAATCAA ACTCTACGGA 
GCTCCAGGTG TGGAGTTCAT GGGGCTTCAC GACGAGAATG CGGCGGTTAC ACAGGTGCAC 
TTCCTGCCAA ACCAGGTGGA GTTGGTCACA TTACTAGAAG ACAACAGTCT ACATATGTGG 
ACACTTCGGG CTCATAACAG CATGTGTGAG CTGCTTGAGA TCGGACGGTT CACTCTCTCT 
GGTCCACCTG GTGCCATTCC CAGCGTGACG CGGGTCACTG CGGTCTTGGC ACACTCATCG 
GGTGAGCTGC TGCTGCTGGG CACAGAAGGA GGACACGTGT TTGTTGTGGA AGTGCCAGGA 
TTCAGAGAAC TGGAGGAGAA CAACATCAGC GTGGAGGACG TACAAAACAG AGTTCCAGAG 
GATTATGTTG GCCGCAGAAA TCTGGAGAGT GTTGAGACTC TTCATGAAAA CCCGCTGAAC 
CCGCGGCAAG TGCTGATTGG CTACAGCCGA GGCCTGATGG TTCTGTGGGA TCTGGACCGG 
CAGCGTCCCG TCCAGCACTT TCTGGGCACA CAGCAACTAG AGAGTGTTTG GTGGATGGAG 
GACGGTGAAA GCATTCTCAG TTCGCACAGT GATGGAAGCT ACTGCCAGTG GACGGTGACC 
GGTGAGGATC CGCAAACAGA GCCAGAGAAG CAGGAGACGC CGTATGGTGC CTTCCCATGC 
AAGGCTATAT CCAAAATTAT ACAGTTGCCA TCAAAACAAG GTCCCCCATT CCTCATCTTC 
AGTGGAGGGA TGCCGAGGGC CAGTTATGGG GACAGACACT GCATTTCTGT CATTCACAGC 
AAAACCCATG AAGCGCTGGA CTTCACCTCT CGCATTATTG ACTTCTTCGT CATTCGTGAA 
GGAGAAAACC ATAAAGGTGA ACCCAGCGCT CTTGTGGTTC TTGTGGAGGA GGAGCTGGTT 
GTGGTGGATC TGCAGACTGA AGGGTGGCCC GTCATCCAGA CGCCATACCT GGTGCCATTA 
CACTGTTCAG CCATCACTTG CTCACACCAC GTCTCCTCCA TCCCTCTCAA ACTGTGGGAG 
AGAGTGCAAG CTGCGGGAGC CCACCAGAAC ACACACTACT CCAGGAAGCC TTGGCCTATA 
AACGGAGGCA AGAATCTGGC CCCAGACCCT CCTCAGAGAG ACCTTCTCCT GACGGGACAT 
GAAGATGGAA CGGTGCGATT CTGGGACGCC TCAGGGGTCT GTCTTTACCC CATGTACAAG 
CTCAGCACAG CAGGAGTCTT CCACACGGAC GCCGATCCAA ACGACAACAT GAACCAGGGC 
AGTGAAGGAG AGTGGCCTCC ATTCCGAAAG GTTGGCTGCT TTGACCCATA TAGCGATGAC 
CCTCGGCTGG GTATTCAGAA GATCCACCTG TGTAAATACA GTGGATATCT CACAGTGGCC 
GGAACTGCAG GACAAATTCT GGTTCTGGAG CTGAATGATG AGGCTGCGGA GCAGATGGTA 
GAAGCTACGG TAGTGGACCT GCTGCAAGGT CAGGAGGGTT TCCGCTGGAA GGGACAGGCG 
CGTCTAGACG TTCGGGAGGA GCCGGTACTG TTTCCTCCAG GCTTTCAGCC ATTCGCCCTG 
GTGCAGTGCC AGCCACCCGC TGTGGTCACC GCAATCGCTC TGCACTCCGA GTGGAAACTA 
GTGGGCTTCG GGACCAGCCA TGGCTTTGGT CTTTATGATT ATAACCAGAG GAATAACATC 
ATGGTCAAAT GCACCCTTAA CCCCAGTGAC CAGATGGCTA TGGAGGGGCC GCTTTCACGA 
GTCAAGTCCA TCAAAAAGTC TCTGCGACAG TCCTTCCGCA GGATTCGCCG CAGTCGAGTC 
TCCATGCGCA AACACCACAC TAACAACGCA GCCAAGCTGC AGGAGATCAA TGCCAGGCTG 
GAGGCTGAGG CTCTGCAGGA GATGGAGCTG GCTCCTGTAC AGAGAAAGAT TGAAGCCCGA 
TCATCTGATG ACTCCTTCAC AGGTCTCGTC AGAACGCTCT ACTTCGCAGA TACATTTGTC 
AGTGATAGTT CTCACAGTAC ACCTTCACTG TGGGCAGGGA CCAATGGCGG AGCTGTGTTT 
GCATATGTCC TCCGTGTCCC ACCACAGGAA CGAAGGGCAG AGGATCCAGT GACGGCTCAT 
GCAGCCAAAG AGATTCAGTT GATGCATCGT GCTCCAGTTG TCGGTTTGGT GGTCTTGGAT 
GGGAAGGGAG CCCCTCTGCC CGAACCCCTA GAAGTGGCAC ATGACCTGGC ACGCAGTCCT 
GAAATGCATG GCTCACACCA TCTATTGGTT GTGTCAGAGG AGCAATTTAA GCTTTTTACA 
TTGCCCAAAG TGAGCAGTAA GTCGAAGCTA AAGCTGACGG CGGTGGATGG CTCTCGTGTG 
CGGCGTGTCG GTGTGGCTTG GTTTGGTTCT CGGACCGATG AACAGTTAGA GAGCTGTCTG 
GTGGTGCTGA CGAATCAGGG GGAGCTCCAC GTCATCTCTC TGCCCTCCAT CAAAATGCTG 
GTCCATTATC CTTGCATACG GAGAGAAGAC GTCAGTGGAA TCGCATCCTG TGTCTTCACC 
AAATATGGCC AAGGTTTCTA CCTGATCTCT CCATCCGAGT TTGAGCGGTT TTCTCTCTCC 
ACCCGTTGGG TCGTGCAACC TCACTGTCTG GTTGAGCCTC CCCTCCAGAT GAGGTCCAAG 
AGCCCATCAA GCCCTGTTCA CAGGGACTTG CCGGATGGAG TACCCACCGA ACACAGAAAT 
TTCAAAGGGG ACAGTGAAGG ATATGGTGTT CTGCAGGAGA TCCAGAAGTC TCTAGAAGGA 
GATCAAACGA CGTTCCTAGA GAACAATCTG AAGACTAAGC CTAAAGCAGG CAATGTGCTG 
AGCAATGGAG ATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

llgl2 ( NM_212582.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_997747.1 Danio rerio LLGL scribble cell polarity complex component 2 (llgl2), mRNA.

Price & Availability↑

CloneID	ODa01122
Clone ID Related Accession (Same CDS sequence)	NM_212582.1
Accession Version	NM_212582.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3063bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Danio rerio(zebrafish)
Product	LLGL scribble cell polarity complex component 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC052919.1. On Jul 6, 2005 this sequence version replaced XM_685685.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC052919.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2168446, SAMEA2168447 [ECO:0000350] ##Evidence-Data-END##

ATGAAGAGGT TCAGGCGTCA TGGGCACGAG TCTCAGAGGG ACAAGCACAA ACAGGATCTC 
TATCAGTTCA ACAAGACTGT AGAGCATGGC TTCCCCCATC AACCTAGCGC TCTGGGATTC 
AGCCCTAGCC TGGAGCTCCT GGCCATCGGC ACCAGATCAG GTGCAATCAA ACTCTACGGA 
GCTCCAGGTG TGGAGTTCAT GGGGCTTCAC GACGAGAATG CGGCGGTTAC ACAGGTGCAC 
TTCCTGCCAA ACCAGGTGGA GTTGGTCACA TTACTAGAAG ACAACAGTCT ACATATGTGG 
ACACTTCGGG CTCATAACAG CATGTGTGAG CTGCTTGAGA TCGGACGGTT CACTCTCTCT 
GGTCCACCTG GTGCCATTCC CAGCGTGACG CGGGTCACTG CGGTCTTGGC ACACTCATCG 
GGTGAGCTGC TGCTGCTGGG CACAGAAGGA GGACACGTGT TTGTTGTGGA AGTGCCAGGA 
TTCAGAGAAC TGGAGGAGAA CAACATCAGC GTGGAGGACG TACAAAACAG AGTTCCAGAG 
GATTATGTTG GCCGCAGAAA TCTGGAGAGT GTTGAGACTC TTCATGAAAA CCCGCTGAAC 
CCGCGGCAAG TGCTGATTGG CTACAGCCGA GGCCTGATGG TTCTGTGGGA TCTGGACCGG 
CAGCGTCCTG TCCAGCACTT TCTGGGCACA CAGCAACTAG AGAGTGTTTG GTGGATGGAG 
GACGGTGAAA GCATTCTCAG TTCGCACAGT GATGGAAGCT ACTGCCAGTG GACGGTGACC 
GGTGAGGATC CGCAAACAGA GCCAGAGAAG CAGGAGACGC CGTATGGTGC CTTCCCATGC 
AAGGCTATAT CCAAAATTAT ACAGTTGCCA TCAAAACAAG GTCCCCCATT CCTCATCTTC 
AGTGGAGGGA TGCCGAGGGC CAGTTATGGG GACAGACACT GCATTTCTGT CATTCACAGC 
AAAACCCATG AAGCGCTGGA CTTCACCTCT CGCATTATTG ACTTCTTCGT CATTCGTGAA 
GGAGAAAACC ATAAAGGTGA ACCCAGCGCT CTTGTGGTTC TAGTGGAGGA GGAGCTGGTT 
GTGGTGGATC TGCAGACTGA AGGGTGGCCC GTCATCCAGA CGCCATACCT GGTGCCATTA 
CACTGTTCAG CCATCACTTG CTCACACCAC GTCTCCTCCA TCCCTCTCAA ACTGTGGGAG 
AGAGTGCAAG CTGCGGGAGC CCACCAGAAC ACACACTACT CCAGGAAGCC TTGGCCTATA 
AACGGAGGCA AGAATCTGGC CCCAGACCCT CCTCAGAGAG ACCTTCTCCT GACGGGACAT 
GAAGATGGAA CGGTGCGATT CTGGGACGCC TCAGGGGTCT GTCTTTACCC CATGTACAAG 
CTCAGCACAG CAGGAGTCTT CCACACGGAC GCCGATCCAA ACGACAACAT GAACCAGGGC 
AGTGAAGGAG AGTGGCCTCC ATTCCGAAAG GTTGGCTGCT TTGACCCATA TAGCGATGAC 
CCTCGGCTGG GTATTCAGAA GATCCACCTG TGTAAATACA GTGGATATCT CACAGTGGCC 
GGAACTGCAG GACAAATTCT GGTTCTGGAG CTGAATGATG AGGCTGCGGA GCAGATGGTA 
GAAGCTACGG TAGTGGACCT GCTGCAAGGT CAGGAGGGTT TCCGCTGGAA GGGACAGGCG 
CGTCTAGACG TTCGGGAGGA GCCGGTACTG TTTCCTCCAG GCTTTCAGCC ATTCGCCCTG 
GTGCAGTGCC AGCCACCCGC TGTGGTCACC GCAATCGCTC TGCACTCCGA GTGGAAACTA 
GTGGGCTTCG GGACCAGCCA TGGCTTTGGT CTTTATGATT ATAACCAGAG GAATAACATC 
ATGGTCAAAT GCACCCTTAA CCCCAGTGAC CAGATGGCTA TGGAGGGGCC GCTGTCACGA 
GTCAAGTCCA TCAAAAAGTC TCTGCGACAG TCCTTCCGCA GGATTCGCCG CAGTCGAGTC 
TCCATGCGCA AACACCACAC TAACAACGCA GCCAAGCTGC AGGAGATCAA TGCCAGGCTG 
GAGGCTGAGG CTCTGCAGGA GATGGAGCTG GCTCCTGTAC AGAGAAAGAT TGAAGCCCGA 
TCATCTGATG ACTCCTTCAC AGGTCTCGTC AGAACGCTCT ACTTCGCAGA TACATTTGTC 
AGTGATAGTT CTCACAGTAC ACCTTCACTG TGGGCAGGGA CCAATGGCGG AGCTGTGTTT 
GCATATGTCC TCCGTGTCCC ACCACAGGAA CGAAGGGCAG AGGATCCAGT GACGGCTCAT 
GCAGCCAAAG AGATTCAGTT GATGCATCGT GCTCCAGTTG TCGGTTTGGT GGTCTTGGAT 
GGGAAGGGAG CCCCTCTGCC CGAACCCCTA GAAGTGGCAC ATGACCTGGC ACGCAGTCCT 
GAAATGCATG GCTCACACCA TCTATTGGTT GTGTCAGAGG AGCAATTTAA GCTTTTTACA 
TTGCCCAAAG TGAGCAGTAA GTCGAAGCTG AAGCTGACGG CGGTGGATGG CTCTCGTGTG 
CGGCGTGTCG GTGTGGCTTG GTTTGGTTCT CGGACCGATG AACAGTTAGA GAGCTGTCTG 
GTGGTGCTGA CGAATCAGGG GGAGCTCCAC GTCATCTCTC TGCCCTCCAT CAAAATGCTG 
GTCCATTATC CTTGCATACG GAGAGAAGAC GTCAGTGGAA TAGCATCCTG TGTCTTCACC 
AAATATGGCC AAGGTTTCTA CCTGATCTCT CCATCCGAGT TTGAGCGGTT TTCTCTCTCC 
ACCCGTTGGG TCGTGCAACC TCACTGTCTG GTTGAGCCTC CCCTCCAGAT GAGGTCCAAG 
AGCCCATCAA GCCCTGTTCA CAGGGACTTG CCGGATGGAG TACCCACCGA ACACAGAAAT 
TTCAAAGGGG ACAGTGAAGG ATATGAGAAT TCTGCTAGAC AAGTAATGGA GCATGCTTTG 
CTCAACGATG AGAGTGTTCT GCAGGAGATC CAGAAGTCTC TAGAAGGAGA TCAAACGACG 
TTCCTAGAGA ACAATCTGAA GACTAAGCCT AAAGCAGGCA ATGTGCTGAG CAATGGAGAT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_997747.1
CDS	235..3297
Translation	MKRFRRHGHESQRDKHKQDLYQFNKTVEHGFPHQPSALGFSPSLELLAIGTRSGAIKLYGAPGVEFMGLHDENAAVTQVHFLPNQVELVTLLEDNSLHMWTLRAHNSMCELLEIGRFTLSGPPGAIPSVTRVTAVLAHSSGELLLLGTEGGHVFVVEVPGFRELEENNISVEDVQNRVPEDYVGRRNLESVETLHENPLNPRQVLIGYSRGLMVLWDLDRQRPVQHFLGTQQLESVWWMEDGESILSSHSDGSYCQWTVTGEDPQTEPEKQETPYGAFPCKAISKIIQLPSKQGPPFLIFSGGMPRASYGDRHCISVIHSKTHEALDFTSRIIDFFVIREGENHKGEPSALVVLVEEELVVVDLQTEGWPVIQTPYLVPLHCSAITCSHHVSSIPLKLWERVQAAGAHQNTHYSRKPWPINGGKNLAPDPPQRDLLLTGHEDGTVRFWDASGVCLYPMYKLSTAGVFHTDADPNDNMNQGSEGEWPPFRKVGCFDPYSDDPRLGIQKIHLCKYSGYLTVAGTAGQILVLELNDEAAEQMVEATVVDLLQGQEGFRWKGQARLDVREEPVLFPPGFQPFALVQCQPPAVVTAIALHSEWKLVGFGTSHGFGLYDYNQRNNIMVKCTLNPSDQMAMEGPLSRVKSIKKSLRQSFRRIRRSRVSMRKHHTNNAAKLQEINARLEAEALQEMELAPVQRKIEARSSDDSFTGLVRTLYFADTFVSDSSHSTPSLWAGTNGGAVFAYVLRVPPQERRAEDPVTAHAAKEIQLMHRAPVVGLVVLDGKGAPLPEPLEVAHDLARSPEMHGSHHLLVVSEEQFKLFTLPKVSSKSKLKLTAVDGSRVRRVGVAWFGSRTDEQLESCLVVLTNQGELHVISLPSIKMLVHYPCIRREDVSGIASCVFTKYGQGFYLISPSEFERFSLSTRWVVQPHCLVEPPLQMRSKSPSSPVHRDLPDGVPTEHRNFKGDSEGYENSARQVMEHALLNDESVLQEIQKSLEGDQTTFLENNLKTKPKAGNVLSNGD

Target ORF information:

RefSeq Version	NM_212582.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio LLGL scribble cell polarity complex component 2 (llgl2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_212582.1

ORF Insert Sequence:

ATGAAGAGGT TCAGGCGTCA TGGGCACGAG TCTCAGAGGG ACAAGCACAA ACAGGATCTC 
TATCAGTTCA ACAAGACTGT AGAGCATGGC TTCCCCCATC AACCTAGCGC TCTGGGATTC 
AGCCCTAGCC TGGAGCTCCT GGCCATCGGC ACCAGATCAG GTGCAATCAA ACTCTACGGA 
GCTCCAGGTG TGGAGTTCAT GGGGCTTCAC GACGAGAATG CGGCGGTTAC ACAGGTGCAC 
TTCCTGCCAA ACCAGGTGGA GTTGGTCACA TTACTAGAAG ACAACAGTCT ACATATGTGG 
ACACTTCGGG CTCATAACAG CATGTGTGAG CTGCTTGAGA TCGGACGGTT CACTCTCTCT 
GGTCCACCTG GTGCCATTCC CAGCGTGACG CGGGTCACTG CGGTCTTGGC ACACTCATCG 
GGTGAGCTGC TGCTGCTGGG CACAGAAGGA GGACACGTGT TTGTTGTGGA AGTGCCAGGA 
TTCAGAGAAC TGGAGGAGAA CAACATCAGC GTGGAGGACG TACAAAACAG AGTTCCAGAG 
GATTATGTTG GCCGCAGAAA TCTGGAGAGT GTTGAGACTC TTCATGAAAA CCCGCTGAAC 
CCGCGGCAAG TGCTGATTGG CTACAGCCGA GGCCTGATGG TTCTGTGGGA TCTGGACCGG 
CAGCGTCCTG TCCAGCACTT TCTGGGCACA CAGCAACTAG AGAGTGTTTG GTGGATGGAG 
GACGGTGAAA GCATTCTCAG TTCGCACAGT GATGGAAGCT ACTGCCAGTG GACGGTGACC 
GGTGAGGATC CGCAAACAGA GCCAGAGAAG CAGGAGACGC CGTATGGTGC CTTCCCATGC 
AAGGCTATAT CCAAAATTAT ACAGTTGCCA TCAAAACAAG GTCCCCCATT CCTCATCTTC 
AGTGGAGGGA TGCCGAGGGC CAGTTATGGG GACAGACACT GCATTTCTGT CATTCACAGC 
AAAACCCATG AAGCGCTGGA CTTCACCTCT CGCATTATTG ACTTCTTCGT CATTCGTGAA 
GGAGAAAACC ATAAAGGTGA ACCCAGCGCT CTTGTGGTTC TAGTGGAGGA GGAGCTGGTT 
GTGGTGGATC TGCAGACTGA AGGGTGGCCC GTCATCCAGA CGCCATACCT GGTGCCATTA 
CACTGTTCAG CCATCACTTG CTCACACCAC GTCTCCTCCA TCCCTCTCAA ACTGTGGGAG 
AGAGTGCAAG CTGCGGGAGC CCACCAGAAC ACACACTACT CCAGGAAGCC TTGGCCTATA 
AACGGAGGCA AGAATCTGGC CCCAGACCCT CCTCAGAGAG ACCTTCTCCT GACGGGACAT 
GAAGATGGAA CGGTGCGATT CTGGGACGCC TCAGGGGTCT GTCTTTACCC CATGTACAAG 
CTCAGCACAG CAGGAGTCTT CCACACGGAC GCCGATCCAA ACGACAACAT GAACCAGGGC 
AGTGAAGGAG AGTGGCCTCC ATTCCGAAAG GTTGGCTGCT TTGACCCATA TAGCGATGAC 
CCTCGGCTGG GTATTCAGAA GATCCACCTG TGTAAATACA GTGGATATCT CACAGTGGCC 
GGAACTGCAG GACAAATTCT GGTTCTGGAG CTGAATGATG AGGCTGCGGA GCAGATGGTA 
GAAGCTACGG TAGTGGACCT GCTGCAAGGT CAGGAGGGTT TCCGCTGGAA GGGACAGGCG 
CGTCTAGACG TTCGGGAGGA GCCGGTACTG TTTCCTCCAG GCTTTCAGCC ATTCGCCCTG 
GTGCAGTGCC AGCCACCCGC TGTGGTCACC GCAATCGCTC TGCACTCCGA GTGGAAACTA 
GTGGGCTTCG GGACCAGCCA TGGCTTTGGT CTTTATGATT ATAACCAGAG GAATAACATC 
ATGGTCAAAT GCACCCTTAA CCCCAGTGAC CAGATGGCTA TGGAGGGGCC GCTGTCACGA 
GTCAAGTCCA TCAAAAAGTC TCTGCGACAG TCCTTCCGCA GGATTCGCCG CAGTCGAGTC 
TCCATGCGCA AACACCACAC TAACAACGCA GCCAAGCTGC AGGAGATCAA TGCCAGGCTG 
GAGGCTGAGG CTCTGCAGGA GATGGAGCTG GCTCCTGTAC AGAGAAAGAT TGAAGCCCGA 
TCATCTGATG ACTCCTTCAC AGGTCTCGTC AGAACGCTCT ACTTCGCAGA TACATTTGTC 
AGTGATAGTT CTCACAGTAC ACCTTCACTG TGGGCAGGGA CCAATGGCGG AGCTGTGTTT 
GCATATGTCC TCCGTGTCCC ACCACAGGAA CGAAGGGCAG AGGATCCAGT GACGGCTCAT 
GCAGCCAAAG AGATTCAGTT GATGCATCGT GCTCCAGTTG TCGGTTTGGT GGTCTTGGAT 
GGGAAGGGAG CCCCTCTGCC CGAACCCCTA GAAGTGGCAC ATGACCTGGC ACGCAGTCCT 
GAAATGCATG GCTCACACCA TCTATTGGTT GTGTCAGAGG AGCAATTTAA GCTTTTTACA 
TTGCCCAAAG TGAGCAGTAA GTCGAAGCTG AAGCTGACGG CGGTGGATGG CTCTCGTGTG 
CGGCGTGTCG GTGTGGCTTG GTTTGGTTCT CGGACCGATG AACAGTTAGA GAGCTGTCTG 
GTGGTGCTGA CGAATCAGGG GGAGCTCCAC GTCATCTCTC TGCCCTCCAT CAAAATGCTG 
GTCCATTATC CTTGCATACG GAGAGAAGAC GTCAGTGGAA TAGCATCCTG TGTCTTCACC 
AAATATGGCC AAGGTTTCTA CCTGATCTCT CCATCCGAGT TTGAGCGGTT TTCTCTCTCC 
ACCCGTTGGG TCGTGCAACC TCACTGTCTG GTTGAGCCTC CCCTCCAGAT GAGGTCCAAG 
AGCCCATCAA GCCCTGTTCA CAGGGACTTG CCGGATGGAG TACCCACCGA ACACAGAAAT 
TTCAAAGGGG ACAGTGAAGG ATATGAGAAT TCTGCTAGAC AAGTAATGGA GCATGCTTTG 
CTCAACGATG AGAGTGTTCT GCAGGAGATC CAGAAGTCTC TAGAAGGAGA TCAAACGACG 
TTCCTAGAGA ACAATCTGAA GACTAAGCCT AAAGCAGGCA ATGTGCTGAG CAATGGAGAT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Evolution of complexity in the zebrafish synapse proteome.
Nature communications814613(2017 Mar)
Bay?s ?,Collins MO,Reig-Viader R,Gou G,Goulding D,Izquierdo A,Choudhary JS,Emes RD,Grant SG

aPKC regulates apical localization of Lgl to restrict elongation of microridges in developing zebrafish epidermis.
Nature communications711643(2016 Jun)
Raman R,Damle I,Rote R,Banerjee S,Dingare C,Sonawane M

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
BMC genomics17368(2016 05)
Pasquier J,Cabau C,Nguyen T,Jouanno E,Severac D,Braasch I,Journot L,Pontarotti P,Klopp C,Postlethwait JH,Guiguen Y,Bobe J

Tumor suppression in basal keratinocytes via dual non-cell-autonomous functions of a Na,K-ATPase beta subunit.
eLife5(2016 05)
Hatzold J,Beleggia F,Herzig H,Altm?ller J,N?rnberg P,Bloch W,Wollnik B,Hammerschmidt M