stx1b cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	stx1b
Entrez Gene ID	58038
Full Name	syntaxin 1B
Synonyms	syntaxin1b,wu:fb76h10,zgc:92909
General protein information	Preferred Names syntaxin 1B Names syntaxin-1B fb76h10
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_131523.1	NP_571598.1	syntaxin-1B

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Stx1b	NP_077725.1
Xenopus tropicalis (tropical clawed frog)	stx1b	NP_001096346.1
Bos taurus (cattle)	STX1B	NP_777043.1
Danio rerio (zebrafish)	stx1b	NP_571598.1
Pan troglodytes (chimpanzee)	STX1B	XP_001145497.1
	LOC714251	XP_001103901.1
Canis lupus familiaris (dog)	STX1B	XP_005621349.1
Homo sapiens (human)	STX1B	NP_443106.1
Rattus norvegicus (Norway rat)	Stx1b	NP_036832.1

Gene Ontology
Bibliography

Related articles in PubMed

Evolution of complexity in the zebrafish synapse proteome.
Bay?s ?, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG
Nature communications814613(2017 Mar)

Proinflammatory Caspase A Activation and an Antiviral State Are Induced by a Zebrafish Perforin after Possible Cellular and Functional Diversification from a Myeloid Ancestor.
Varela M, Forn-Cun? G, Dios S, Figueras A, Novoa B
Journal of innate immunity8(1)43-56(2016)

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

Mutations in STX1B, encoding a presynaptic protein, cause fever-associated epilepsy syndromes.
Schubert J, Siekierska A, Langlois M, May P, Huneau C, Becker F, Muhle H, Suls A, Lemke JR, de Kovel CG, Thiele H, Konrad K, Kawalia A, Toliat MR, Sander T, R?schendorf F, Caliebe A, Nagel I, Kohl B, Kecsk?s A, Jacmin M, Hardies K, Weckhuysen S, Riesch E, Dorn T, Brilstra EH, Baulac S, M?ller RS, Hjalgrim H, Koeleman BP, , Jurkat-Rott K, Lehman-Horn F, Roach JC, Glusman G, Hood L, Galas DJ, Martin B, de Witte PA, Biskup S, De Jonghe P, Helbig I, Balling R, N?rnberg P, Crawford AD, Esguerra CV, Weber YG, Lerche H
Nature genetics46(12)1327-32(2014 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following stx1b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the stx1b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa37015	NM_131523.1 Latest version!	Danio rerio syntaxin 1B (stx1b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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5 or more Clone	50% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

stx1b ( NM_131523.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_571598.1 Danio rerio syntaxin 1B (stx1b), mRNA.

Price & Availability↑

CloneID	ODa37015
Clone ID Related Accession (Same CDS sequence)	NM_131523.1
Accession Version	NM_131523.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 867bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-27
Organism	Danio rerio(zebrafish)
Product	syntaxin-1B
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF229154.1. ##Evidence-Data-START## Transcript exon combination :: AF229154.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476760, SAMEA4476808 [ECO:0000348] ##Evidence-Data-END##

ATGAAGGATC GCACGCAGGA ACTACGAAGT GCTAAGGACA GTGACGATGA CGAGGAAGTC 
GTTCATGTCG ACCGAGACCA CTTTATGGAT GAATTTTTCG AACAGGTGGA GGAGATCCGC 
GGCTGTATTG AAAAGCTGTC AGAGGATGTG GAACAGGTGA AGAAGCAGCA CAGTGCCATC 
CTAGCAGCAC CAAACCCTGA TGAAAAGACT AAGCAGGAGT TGGAGGACCT CACAGCTGAC 
ATTAAGAAGA CAGCCAATAA AGTGCGCTCT AAATTAAAAG CTATCGAACA AAGTATCGAG 
CAAGAGGAAG GGTTGAACAG ATCATCTGCA GATTTGCGGA TCCGCAAGAC ACAGCATTCC 
ACGCTGTCAC GCAAGTTTGT GGAGGTGATG ACAGAGTACA ACACCACGCA GTCCAAATAC 
AGGGACCGCT GCAAGGACCG TATTCAGAGA CAACTGGAAA TTACTGGCAG AACAACTACC 
AATGAGGAGC TGGAAGACAT GTTGGAGAGT GGGAAGCTTG CAATCTTCAC TGATGATATC 
AAAATGGACT CCCAGATGAC CAAGCAGGCA CTAAATGAGA TTGAGACCCG ACACACTGAG 
ATCATTAAGT TGGAGAACAG CATCCGTGAG CTGCACGATA TGTTTGTGGA CATGGCCATG 
CTGGTGGAGA GTCAGGGAGA GATGATTGAC AGAATTGAGT ATAACGTGGA ACACTCTGTG 
GACTATGTAG AGAGAGCGGT TTCTGACACC AAGAAGGCTG TCAAATACCA GAGTCAGGCA 
CGCAAGAAGA AGATCATGAT CATCATCTGC TGTGTAATTT TGGGAGTGGT TTTGCGGTCC 
AGTATCGGAG GAACCCTGGG CTTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_571598.1
CDS	1..867
Translation	MKDRTQELRSAKDSDDDEEVVHVDRDHFMDEFFEQVEEIRGCIEKLSEDVEQVKKQHSAILAAPNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMTEYNTTQSKYRDRCKDRIQRQLEITGRTTTNEELEDMLESGKLAIFTDDIKMDSQMTKQALNEIETRHTEIIKLENSIRELHDMFVDMAMLVESQGEMIDRIEYNVEHSVDYVERAVSDTKKAVKYQSQARKKKIMIIICCVILGVVLRSSIGGTLGF

Target ORF information:

RefSeq Version	NM_131523.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio syntaxin 1B (stx1b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_131523.1

ORF Insert Sequence:

ATGAAGGATC GCACGCAGGA ACTACGAAGT GCTAAGGACA GTGACGATGA CGAGGAAGTC 
GTTCATGTCG ACCGAGACCA CTTTATGGAT GAATTTTTCG AACAGGTGGA GGAGATCCGC 
GGCTGTATTG AAAAGCTGTC AGAGGATGTG GAACAGGTGA AGAAGCAGCA CAGTGCCATC 
CTAGCAGCAC CAAACCCTGA TGAAAAGACT AAGCAGGAGT TGGAGGACCT CACAGCTGAC 
ATTAAGAAGA CAGCCAATAA AGTGCGCTCT AAATTAAAAG CTATCGAACA AAGTATCGAG 
CAAGAGGAAG GGTTGAACAG ATCATCTGCA GATTTGCGGA TCCGCAAGAC ACAGCATTCC 
ACGCTGTCAC GCAAGTTTGT GGAGGTGATG ACAGAGTACA ACACCACGCA GTCCAAATAC 
AGGGACCGCT GCAAGGACCG TATTCAGAGA CAACTGGAAA TTACTGGCAG AACAACTACC 
AATGAGGAGC TGGAAGACAT GTTGGAGAGT GGGAAGCTTG CAATCTTCAC TGATGATATC 
AAAATGGACT CCCAGATGAC CAAGCAGGCA CTAAATGAGA TTGAGACCCG ACACACTGAG 
ATCATTAAGT TGGAGAACAG CATCCGTGAG CTGCACGATA TGTTTGTGGA CATGGCCATG 
CTGGTGGAGA GTCAGGGAGA GATGATTGAC AGAATTGAGT ATAACGTGGA ACACTCTGTG 
GACTATGTAG AGAGAGCGGT TTCTGACACC AAGAAGGCTG TCAAATACCA GAGTCAGGCA 
CGCAAGAAGA AGATCATGAT CATCATCTGC TGTGTAATTT TGGGAGTGGT TTTGCGGTCC 
AGTATCGGAG GAACCCTGGG CTTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Evolution of complexity in the zebrafish synapse proteome.
Nature communications814613(2017 Mar)
Bay?s ?,Collins MO,Reig-Viader R,Gou G,Goulding D,Izquierdo A,Choudhary JS,Emes RD,Grant SG

Proinflammatory Caspase A Activation and an Antiviral State Are Induced by a Zebrafish Perforin after Possible Cellular and Functional Diversification from a Myeloid Ancestor.
Journal of innate immunity8(1)43-56(2016)
Varela M,Forn-Cun? G,Dios S,Figueras A,Novoa B

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

Mutations in STX1B, encoding a presynaptic protein, cause fever-associated epilepsy syndromes.
Nature genetics46(12)1327-32(2014 Dec)
Schubert J,Siekierska A,Langlois M,May P,Huneau C,Becker F,Muhle H,Suls A,Lemke JR,de Kovel CG,Thiele H,Konrad K,Kawalia A,Toliat MR,Sander T,R?schendorf F,Caliebe A,Nagel I,Kohl B,Kecsk?s A,Jacmin M,Hardies K,Weckhuysen S,Riesch E,Dorn T,Brilstra EH,Baulac S,M?ller RS,Hjalgrim H,Koeleman BP,,Jurkat-Rott K,Lehman-Horn F,Roach JC,Glusman G,Hood L,Galas DJ,Martin B,de Witte PA,Biskup S,De Jonghe P,Helbig I,Balling R,N?rnberg P,Crawford AD,Esguerra CV,Weber YG,Lerche H

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stx1b cDNA ORF clone, Danio rerio(zebrafish)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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