snx6 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	snx6
Entrez Gene ID	567182
Full Name	sorting nexin 6
Synonyms	im:7146294,wu:fa55b10,zgc:110798
General protein information	Preferred Names sorting nexin 6 Names sorting nexin-6 fa55b10
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001030217.2	NP_001025388.2	sorting nexin-6

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	SNX6	XP_001134882.1
Caenorhabditis elegans (roundworm)	snx-6	NP_001256763.1
Rattus norvegicus (Norway rat)	Snx6	NP_001102181.1
Gallus gallus (chicken)	SNX6	NP_001073225.1
Drosophila melanogaster (fruit fly)	Snx6	NP_001245939.1
Canis lupus familiaris (dog)	SNX6	XP_547770.4
Mus musculus (house mouse)	Snx6	NP_081274.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004487	XP_313785.3
Danio rerio (zebrafish)	snx6	NP_001025388.1
Xenopus tropicalis (tropical clawed frog)	snx6	NP_988999.1
Homo sapiens (human)	SNX6	NP_689419.2

Gene Ontology
Bibliography

Related articles in PubMed

Evolution of complexity in the zebrafish synapse proteome.
Bay?s ?, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG
Nature communications814613(2017 Mar)

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

SMN deficiency alters Nrxn2 expression and splicing in zebrafish and mouse models of spinal muscular atrophy.
See K, Yadav P, Giegerich M, Cheong PS, Graf M, Vyas H, Lee SG, Mathavan S, Fischer U, Sendtner M, Winkler C
Human molecular genetics23(7)1754-70(2014 Apr)

An antiapoptotic role of sorting nexin 7 is required for liver development in zebrafish.
Xu L, Yin W, Xia J, Peng M, Li S, Lin S, Pei D, Shu X
Hepatology (Baltimore, Md.)55(6)1985-93(2012 Jun)

Snx5, as a Mind bomb-binding protein, is expressed in hematopoietic and endothelial precursor cells in zebrafish.
Yoo KW, Kim EH, Jung SH, Rhee M, Koo BK, Yoon KJ, Kong YY, Kim CH
FEBS letters580(18)4409-16(2006 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following snx6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the snx6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa53406	NM_001030217.2 Latest version!	Danio rerio sorting nexin 6 (snx6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$258.30 $369.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

snx6 ( NM_001030217.2 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001025388.2 Danio rerio sorting nexin 6 (snx6), mRNA.

Price & Availability↑

CloneID	ODa53406
Clone ID Related Accession (Same CDS sequence)	NM_001030217.2
Accession Version	NM_001030217.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1224bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-01-26
Organism	Danio rerio(zebrafish)
Product	sorting nexin-6
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CU463180.11. On Jun 18, 2016 this sequence version replaced NM_001030217.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC096497.1, GDQH01026464.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2168446, SAMEA2168447 [ECO:0000350] ##Evidence-Data-END##

ATGATGCAAG AAGGGCTGGA CGACGGTCCC GATTTTCTTT CAGAAGAGGA CAGAGGACCC 
AGGGCGGTGA ATGTGGATCT TCAGACTGAC GCTACACTAC AGGTGGACAT TTCAGACGCT 
CTGAGTGAGA GAGACAAGGT CAAGTTCACC GTCCACACAA AGAGCACTCT ACCTAATTTC 
AAGCAGAATG AATTTTCCGT GGTCAGACAG CATGAAGAAT TTATCTGGCT CCACGACTCG 
TTTGTGGAAA ATGAAGAATA TGCAGGATAT ATTATTCCTC CTGCCCCTCC GAGACCGGAT 
TTCGACGCTT CACGGGAGAA GCTCCAGAAA CTCGGAGAAG GTGAAGGATC GATGACGAAG 
GAGGAGTTCA CCAAGATGAA GCAGGAACTG GAGGCTGAAT ATCTGGCCAT CTTCAAGAAG 
ACTGTGGCGA TGCATGAGGT CTTTCTGTGC CGCGTTGCTG CCCATCCTGT CCTGCGCAAA 
GACTTGAACT TTCACGTTTT CTTAGAGTAC AACCAAGACC TGAGTGTACG AGGGAAGAAC 
AAGAAGGAGA AACTGGAGGA TTTCTTTAAG AACGTGGTGA AATCTGCAGA CGGGGTTCTG 
GTGGCTGGAG TGAAGGACGT TGATGATTTC TTTGAACATG AGAAGACATT CCTTTTAGAG 
TATCACAACC GAGTCAAAGA CTCCTCTGCC AAATCCGACC GAATGATCAG GTCTCACAAA 
AGTGCAGCGG ATGACATCAA CAGAATCGCC TCCACGCTCT ACACTTTAGG AACTCAAGAC 
TCCACAGATC TGTGCAAATT TTTCCTGAAA GTATCAGAGC TTTTTGAGAA AACACGGAAA 
ATTGAAGCGC GTGTGGCGGC CGATGAGGAC CTGAAGCTTG CAGACCTGTT GAAGTATTAC 
CTCCGAGAGT CTCAGGCGGC AAAGGACCTG CTGTACAGAC GAGGACGGGC ATTAGTTGAT 
TATGAGAATG CTAATAAAGC GTTGGACAAA GCCAGAGCTA AAAACAAGGA CGTCCTTCAA 
GCAGAAACCA CACAGCAAGT GTGCTGTCAG AAGTTTGAGA AAATCTCTGA ATCTGCAAAA 
CAAGAACTGA TAGATTTCAA GACACGGCGA GTAGCAGCGT TCAGAAAGAA CCTGGTGGAA 
CTGGCAGAGC TGGAACTCAA ACATGCCAAG GGGAATCTAC AACTGCTGCA GAGCTGCCTG 
GGAGTCCTGA AAGGGGACAC TTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001025388.2
CDS	21..1244
Translation	MMQEGLDDGPDFLSEEDRGPRAVNVDLQTDATLQVDISDALSERDKVKFTVHTKSTLPNFKQNEFSVVRQHEEFIWLHDSFVENEEYAGYIIPPAPPRPDFDASREKLQKLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPVLRKDLNFHVFLEYNQDLSVRGKNKKEKLEDFFKNVVKSADGVLVAGVKDVDDFFEHEKTFLLEYHNRVKDSSAKSDRMIRSHKSAADDINRIASTLYTLGTQDSTDLCKFFLKVSELFEKTRKIEARVAADEDLKLADLLKYYLRESQAAKDLLYRRGRALVDYENANKALDKARAKNKDVLQAETTQQVCCQKFEKISESAKQELIDFKTRRVAAFRKNLVELAELELKHAKGNLQLLQSCLGVLKGDT

Target ORF information:

RefSeq Version	NM_001030217.2
Organism	Danio rerio(zebrafish)
Definition	Danio rerio sorting nexin 6 (snx6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001030217.2

ORF Insert Sequence:

ATGATGCAAG AAGGGCTGGA CGACGGTCCC GATTTTCTTT CAGAAGAGGA CAGAGGACCC 
AGGGCGGTGA ATGTGGATCT TCAGACTGAC GCTACACTAC AGGTGGACAT TTCAGACGCT 
CTGAGTGAGA GAGACAAGGT CAAGTTCACC GTCCACACAA AGAGCACTCT ACCTAATTTC 
AAGCAGAATG AATTTTCCGT GGTCAGACAG CATGAAGAAT TTATCTGGCT CCACGACTCG 
TTTGTGGAAA ATGAAGAATA TGCAGGATAT ATTATTCCTC CTGCCCCTCC GAGACCGGAT 
TTCGACGCTT CACGGGAGAA GCTCCAGAAA CTCGGAGAAG GTGAAGGATC GATGACGAAG 
GAGGAGTTCA CCAAGATGAA GCAGGAACTG GAGGCTGAAT ATCTGGCCAT CTTCAAGAAG 
ACTGTGGCGA TGCATGAGGT CTTTCTGTGC CGCGTTGCTG CCCATCCTGT CCTGCGCAAA 
GACTTGAACT TTCACGTTTT CTTAGAGTAC AACCAAGACC TGAGTGTACG AGGGAAGAAC 
AAGAAGGAGA AACTGGAGGA TTTCTTTAAG AACGTGGTGA AATCTGCAGA CGGGGTTCTG 
GTGGCTGGAG TGAAGGACGT TGATGATTTC TTTGAACATG AGAAGACATT CCTTTTAGAG 
TATCACAACC GAGTCAAAGA CTCCTCTGCC AAATCCGACC GAATGATCAG GTCTCACAAA 
AGTGCAGCGG ATGACATCAA CAGAATCGCC TCCACGCTCT ACACTTTAGG AACTCAAGAC 
TCCACAGATC TGTGCAAATT TTTCCTGAAA GTATCAGAGC TTTTTGAGAA AACACGGAAA 
ATTGAAGCGC GTGTGGCGGC CGATGAGGAC CTGAAGCTTG CAGACCTGTT GAAGTATTAC 
CTCCGAGAGT CTCAGGCGGC AAAGGACCTG CTGTACAGAC GAGGACGGGC ATTAGTTGAT 
TATGAGAATG CTAATAAAGC GTTGGACAAA GCCAGAGCTA AAAACAAGGA CGTCCTTCAA 
GCAGAAACCA CACAGCAAGT GTGCTGTCAG AAGTTTGAGA AAATCTCTGA ATCTGCAAAA 
CAAGAACTGA TAGATTTCAA GACACGGCGA GTAGCAGCGT TCAGAAAGAA CCTGGTGGAA 
CTGGCAGAGC TGGAACTCAA ACATGCCAAG GGGAATCTAC AACTGCTGCA GAGCTGCCTG 
GGAGTCCTGA AAGGGGACAC TTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Evolution of complexity in the zebrafish synapse proteome.
Nature communications814613(2017 Mar)
Bay?s ?,Collins MO,Reig-Viader R,Gou G,Goulding D,Izquierdo A,Choudhary JS,Emes RD,Grant SG

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

SMN deficiency alters Nrxn2 expression and splicing in zebrafish and mouse models of spinal muscular atrophy.
Human molecular genetics23(7)1754-70(2014 Apr)
See K,Yadav P,Giegerich M,Cheong PS,Graf M,Vyas H,Lee SG,Mathavan S,Fischer U,Sendtner M,Winkler C

An antiapoptotic role of sorting nexin 7 is required for liver development in zebrafish.
Hepatology (Baltimore, Md.)55(6)1985-93(2012 Jun)
Xu L,Yin W,Xia J,Peng M,Li S,Lin S,Pei D,Shu X

Snx5, as a Mind bomb-binding protein, is expressed in hematopoietic and endothelial precursor cells in zebrafish.
FEBS letters580(18)4409-16(2006 Aug)
Yoo KW,Kim EH,Jung SH,Rhee M,Koo BK,Yoon KJ,Kong YY,Kim CH