foxo6b cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	foxo6b
Entrez Gene ID	566899
Full Name	forkhead box O6 b
Synonyms	foxo6,foxo6a,si:ch211-206a7.2
General protein information	Preferred Names forkhead box O6 b Names uncharacterized protein LOC566899 forkhead box O6b
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001135132.2	NP_001128604.2	uncharacterized protein LOC566899

Pathways from BioSystems

Homologies

Homo sapiens (human)	FOXO6	XP_002342143.5
Rattus norvegicus (Norway rat)	Foxo6	XP_001057233.1
Danio rerio (zebrafish)	si:ch211-206a7.2	NP_001128604.1
Danio rerio (zebrafish)	LOC101883250	XP_005157925.1
Xenopus tropicalis (tropical clawed frog)	foxo6	XP_002939401.1
Mus musculus (house mouse)	Foxo6	NP_918949.1
Gallus gallus (chicken)	LOC100857767	XP_004947769.1
Danio rerio (zebrafish)	LOC561541	XP_690041.2

Gene Ontology
Bibliography

Related articles in PubMed

The Calcineurin-FoxO-MuRF1 signaling pathway regulates myofibril integrity in cardiomyocytes.
Shimizu H, Langenbacher AD, Huang J, Wang K, Otto G, Geisler R, Wang Y, Chen JN
eLife6(2017 Aug)

Spatiotemporal expression of foxo4, foxo6a, and foxo6b in the developing brain and retina are transcriptionally regulated by PI3K signaling in zebrafish.
Lin SJ, Chiang MC, Shih HY, Chiang KC, Cheng YC
Development genes and evolution227(3)219-230(2017 Jun)

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y, Bobe J
BMC genomics17368(2016 05)

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results suggest that foxo4, foxo6a, and foxo6b play important roles in the developing brain and retina and that the transcriptional levels of these genes are regulated by PI3-kinase signaling.
Title: Spatiotemporal expression of foxo4, foxo6a, and foxo6b in the developing brain and retina are transcriptionally regulated by PI3K signaling in zebrafish.

The following foxo6b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the foxo6b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa98434	NM_001135132.2 Latest version!	Danio rerio forkhead box O6 b (foxo6b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$426.30 $609.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

foxo6b ( NM_001135132.2 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001128604.2 Danio rerio forkhead box O6 b (foxo6b), mRNA.

Price & Availability↑

CloneID	ODa98434
Clone ID Related Accession (Same CDS sequence)	NM_001135132.2
Accession Version	NM_001135132.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2145bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-12
Organism	Danio rerio(zebrafish)
Product	uncharacterized protein LOC566899
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC167973.1 and AL954143.10. On May 19, 2016 this sequence version replaced NM_001135132.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BC167973.1, GFIL01035840.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##

ATGTTAATGA TGGAGAGCAG CGGGATAGAC GCGCATCAGG TTGAACTGGA CGCCGACTAT 
GAGCCGCACT GCCGACCGAG GTCGTGCACC TGGCCGCTGC CGTGTCCGGA GGAGGAGAGC 
CGTGCGCTGC CTGTGAAAGT GGAGCCGCGC AACGTGCCGG CGTGCCGGAG CGGTGGGGCG 
CCGACGGAGT TCAAGCATCC AGCCGGCGCC CCTGCCCCTA TAGCGGCAGC CCCAGCGTGC 
ATGTCCGGCG CCGCGCTGGA TGTGGCCGGC CAGCTGCGCA AATCCAAGTC GTCGCGACGG 
AACGCGTGGG GCAACCAGTC CTACGCGGAT CTGATCACGC GTGCCATTGA GAGCACCCCA 
GAGAAAAGGC TCACCTTATC GCAAATCTAT GACTGGATGG TGCGATTTGT GCCATATTTC 
AAGGATAAAG GAGACAGCAA TAGCTCAGCC GGCTGGAAGA ACTCCATTAG ACACAACCTC 
TCCCTGCATA CCAGATTCAT CCGTGTTCAA AATGAGGGAA CAGGAAAAAG TTCCTGGTGG 
ATGCTTAACC CGGAAGGTGG GAAAATGGGC AAAGGACCCC GCAGACGAGC TGTATCCATG 
GACAATGGCA CTAAGTACCT GAAGAGCAGA GGCAGAGTCA GCAGGAAGAG AACAGCGGCT 
GTGGGAATGG GTAGAGAGCT TGGAGCACCT GGAATACAGG GATCGCCTGA ACATGGAAGC 
CCAGCAGGGA AGGGAGTAAT GGGCATTGGA AGTGAAGAGT TTGATGCCTG GACAGACCTT 
CACTCCAGAA CAAGTTCCTC TGCATCAACG TTAAGTGGAT GCTTGTCTCC TATTCTGGCT 
GAGACAGAAC CTGATGAACC AGAGGAAGGA GGACTTTCTT GTTCAGCCTC CCCACGACTC 
TACCCTAGCC CCACCAGCAC AAGATCTCCA GCACTGGGAA CAGGTGGACA TTGTCCATCT 
GTTGAGCTTC CGCATCTAGC TGATCTAACT GGAGCAATCA GCTTGGAAGA GGGCTACTCC 
CAGCCTCTAC CACTTAAGCG CAATGGATAT CACTATGGCC CTGCACCTAA AGCAGAGACC 
TCCTACTGTG GTACAGTCTA TGGCCAACCA TCCATGGGCA TGCTTAGGCA TCATACGCCT 
ATGCAGACTA TTCAGGAAAA TAAGCCTACT AGCTTCCAGC GTGCCCTTAG GGCATACTCA 
GAGAACAATG CCCTTGAAAG TTTGCTTGCT GGAGGGCCAC AATACTGTGG TAAGGACATG 
GTTGTGGGGC AAGGAGGAAC ATCTCATTCA CTTATGTCAC AATCTAATAC TGCTGTGCAT 
TCTCACGGCC ACAATCAGAG CCACAATCAC AGCCAGAATC ACAATCATAA CCCAGAGCAT 
GGCCACAATC GCAATTCCAG TCAAAGCCTT CACAATGGTC ATGGAGTAAC TCATGAGCAA 
AACCCAAGCC ATCATCACAA TCCCAATCAA GCTCATAATA AGCATCACCC AAGTCTTGAT 
TACAATCACC ATAAACAACA CCGTGGCCAT GACTATGTTC AATCTCATGA CCACAAACTC 
AATGCTAGTC CCAATCACAT GCACAATCAC CTTCAGCATA ACAATTCCAG ACAACCAGAT 
CTTTCTCCTA GGGTGAGCAA TGACATGTTG CAACCCTACA ACCACAAATC ACCCAGCCTT 
TATGGCCCAC GTGCTCATCT TCCTTCTACT GCTCTGCCTC CTAACCCTGC CAGTGTCTTG 
GATGTACCCC AAGACCCATG TCGCCTGGCT TCAGCTCCCC ATCCTCGCCA TCAATCCTAC 
CCAGGTTCCC ACCTCCACCA GGGCATGACA GAACCCTGGC AGGGGTATTA CCACCACACA 
TCACAGAATG CTAATTACCA TGGAAACCAC CAAGCTAGCC ATCACCATGA TCCTCAAAAT 
CGGTTGCAAT CTGAGCTGGA AATGGATGTG CACCAGAGCA GTTTGGATTG TGATGTGGAA 
TCCATCCTCC TGAATGACTT TATGGACTCA ACAGAGGGAA TGGACTTTAA CTTTGACGGG 
TCATTATCAC AGGGTGTGGG CATGGGAATG GGTTTGGGGA TGGGAATGGG AGTTTTTGCA 
GGACCTCAAC AATCACACAA TAGCCAGAGT TGGGTGCCTG GGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001128604.2
CDS	228..2372
Translation	MLMMESSGIDAHQVELDADYEPHCRPRSCTWPLPCPEEESRALPVKVEPRNVPACRSGGAPTEFKHPAGAPAPIAAAPACMSGAALDVAGQLRKSKSSRRNAWGNQSYADLITRAIESTPEKRLTLSQIYDWMVRFVPYFKDKGDSNSSAGWKNSIRHNLSLHTRFIRVQNEGTGKSSWWMLNPEGGKMGKGPRRRAVSMDNGTKYLKSRGRVSRKRTAAVGMGRELGAPGIQGSPEHGSPAGKGVMGIGSEEFDAWTDLHSRTSSSASTLSGCLSPILAETEPDEPEEGGLSCSASPRLYPSPTSTRSPALGTGGHCPSVELPHLADLTGAISLEEGYSQPLPLKRNGYHYGPAPKAETSYCGTVYGQPSMGMLRHHTPMQTIQENKPTSFQRALRAYSENNALESLLAGGPQYCGKDMVVGQGGTSHSLMSQSNTAVHSHGHNQSHNHSQNHNHNPEHGHNRNSSQSLHNGHGVTHEQNPSHHHNPNQAHNKHHPSLDYNHHKQHRGHDYVQSHDHKLNASPNHMHNHLQHNNSRQPDLSPRVSNDMLQPYNHKSPSLYGPRAHLPSTALPPNPASVLDVPQDPCRLASAPHPRHQSYPGSHLHQGMTEPWQGYYHHTSQNANYHGNHQASHHHDPQNRLQSELEMDVHQSSLDCDVESILLNDFMDSTEGMDFNFDGSLSQGVGMGMGLGMGMGVFAGPQQSHNSQSWVPG

Target ORF information:

RefSeq Version	NM_001135132.2
Organism	Danio rerio(zebrafish)
Definition	Danio rerio forkhead box O6 b (foxo6b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001135132.2

ORF Insert Sequence:

ATGTTAATGA TGGAGAGCAG CGGGATAGAC GCGCATCAGG TTGAACTGGA CGCCGACTAT 
GAGCCGCACT GCCGACCGAG GTCGTGCACC TGGCCGCTGC CGTGTCCGGA GGAGGAGAGC 
CGTGCGCTGC CTGTGAAAGT GGAGCCGCGC AACGTGCCGG CGTGCCGGAG CGGTGGGGCG 
CCGACGGAGT TCAAGCATCC AGCCGGCGCC CCTGCCCCTA TAGCGGCAGC CCCAGCGTGC 
ATGTCCGGCG CCGCGCTGGA TGTGGCCGGC CAGCTGCGCA AATCCAAGTC GTCGCGACGG 
AACGCGTGGG GCAACCAGTC CTACGCGGAT CTGATCACGC GTGCCATTGA GAGCACCCCA 
GAGAAAAGGC TCACCTTATC GCAAATCTAT GACTGGATGG TGCGATTTGT GCCATATTTC 
AAGGATAAAG GAGACAGCAA TAGCTCAGCC GGCTGGAAGA ACTCCATTAG ACACAACCTC 
TCCCTGCATA CCAGATTCAT CCGTGTTCAA AATGAGGGAA CAGGAAAAAG TTCCTGGTGG 
ATGCTTAACC CGGAAGGTGG GAAAATGGGC AAAGGACCCC GCAGACGAGC TGTATCCATG 
GACAATGGCA CTAAGTACCT GAAGAGCAGA GGCAGAGTCA GCAGGAAGAG AACAGCGGCT 
GTGGGAATGG GTAGAGAGCT TGGAGCACCT GGAATACAGG GATCGCCTGA ACATGGAAGC 
CCAGCAGGGA AGGGAGTAAT GGGCATTGGA AGTGAAGAGT TTGATGCCTG GACAGACCTT 
CACTCCAGAA CAAGTTCCTC TGCATCAACG TTAAGTGGAT GCTTGTCTCC TATTCTGGCT 
GAGACAGAAC CTGATGAACC AGAGGAAGGA GGACTTTCTT GTTCAGCCTC CCCACGACTC 
TACCCTAGCC CCACCAGCAC AAGATCTCCA GCACTGGGAA CAGGTGGACA TTGTCCATCT 
GTTGAGCTTC CGCATCTAGC TGATCTAACT GGAGCAATCA GCTTGGAAGA GGGCTACTCC 
CAGCCTCTAC CACTTAAGCG CAATGGATAT CACTATGGCC CTGCACCTAA AGCAGAGACC 
TCCTACTGTG GTACAGTCTA TGGCCAACCA TCCATGGGCA TGCTTAGGCA TCATACGCCT 
ATGCAGACTA TTCAGGAAAA TAAGCCTACT AGCTTCCAGC GTGCCCTTAG GGCATACTCA 
GAGAACAATG CCCTTGAAAG TTTGCTTGCT GGAGGGCCAC AATACTGTGG TAAGGACATG 
GTTGTGGGGC AAGGAGGAAC ATCTCATTCA CTTATGTCAC AATCTAATAC TGCTGTGCAT 
TCTCACGGCC ACAATCAGAG CCACAATCAC AGCCAGAATC ACAATCATAA CCCAGAGCAT 
GGCCACAATC GCAATTCCAG TCAAAGCCTT CACAATGGTC ATGGAGTAAC TCATGAGCAA 
AACCCAAGCC ATCATCACAA TCCCAATCAA GCTCATAATA AGCATCACCC AAGTCTTGAT 
TACAATCACC ATAAACAACA CCGTGGCCAT GACTATGTTC AATCTCATGA CCACAAACTC 
AATGCTAGTC CCAATCACAT GCACAATCAC CTTCAGCATA ACAATTCCAG ACAACCAGAT 
CTTTCTCCTA GGGTGAGCAA TGACATGTTG CAACCCTACA ACCACAAATC ACCCAGCCTT 
TATGGCCCAC GTGCTCATCT TCCTTCTACT GCTCTGCCTC CTAACCCTGC CAGTGTCTTG 
GATGTACCCC AAGACCCATG TCGCCTGGCT TCAGCTCCCC ATCCTCGCCA TCAATCCTAC 
CCAGGTTCCC ACCTCCACCA GGGCATGACA GAACCCTGGC AGGGGTATTA CCACCACACA 
TCACAGAATG CTAATTACCA TGGAAACCAC CAAGCTAGCC ATCACCATGA TCCTCAAAAT 
CGGTTGCAAT CTGAGCTGGA AATGGATGTG CACCAGAGCA GTTTGGATTG TGATGTGGAA 
TCCATCCTCC TGAATGACTT TATGGACTCA ACAGAGGGAA TGGACTTTAA CTTTGACGGG 
TCATTATCAC AGGGTGTGGG CATGGGAATG GGTTTGGGGA TGGGAATGGG AGTTTTTGCA 
GGACCTCAAC AATCACACAA TAGCCAGAGT TGGGTGCCTG GGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The Calcineurin-FoxO-MuRF1 signaling pathway regulates myofibril integrity in cardiomyocytes.
eLife6(2017 Aug)
Shimizu H,Langenbacher AD,Huang J,Wang K,Otto G,Geisler R,Wang Y,Chen JN

Spatiotemporal expression of foxo4, foxo6a, and foxo6b in the developing brain and retina are transcriptionally regulated by PI3K signaling in zebrafish.
Development genes and evolution227(3)219-230(2017 Jun)
Lin SJ,Chiang MC,Shih HY,Chiang KC,Cheng YC

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
BMC genomics17368(2016 05)
Pasquier J,Cabau C,Nguyen T,Jouanno E,Severac D,Braasch I,Journot L,Pontarotti P,Klopp C,Postlethwait JH,Guiguen Y,Bobe J

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

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foxo6b cDNA ORF clone, Danio rerio(zebrafish)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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