ids cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	ids
Entrez Gene ID	559959
Full Name	iduronate 2-sulfatase
Synonyms	zgc:158245
General protein information	Preferred Names iduronate 2-sulfatase Names iduronate 2-sulfatase
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
XM_009291036.2	XP_009289311.1	iduronate 2-sulfatase isoform X1
NM_001080068.1	NP_001073537.1	iduronate 2-sulfatase precursor

Pathways from BioSystems

Homologies

	IDS	XP_001089323.1
Danio rerio (zebrafish)	ids	NP_001073537.1
Drosophila melanogaster (fruit fly)	CG12014	NP_647814.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP005778	XP_315795.4
Mus musculus (house mouse)	Ids	NP_034628.2
Rattus norvegicus (Norway rat)	Ids	XP_006243311.1
Gallus gallus (chicken)	IDS	NP_001264589.1
Xenopus tropicalis (tropical clawed frog)	ids	NP_001184061.1
Homo sapiens (human)	IDS	NP_000193.1
Pan troglodytes (chimpanzee)	IDS	XP_521297.4
Canis lupus familiaris (dog)	IDS	NP_001041590.1
Bos taurus (cattle)	IDS	NP_001179780.1

Gene Ontology
Bibliography

Related articles in PubMed

Perturbations in cell signaling elicit early cardiac defects in mucopolysaccharidosis type II.
Costa R, Urbani A, Salvalaio M, Bellesso S, Cieri D, Zancan I, Filocamo M, Bonaldo P, Szab? I, Tomanin R, Moro E
Human molecular genetics26(9)1643-1655(2017 05)

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

A novel functional role of iduronate-2-sulfatase in zebrafish early development.
Moro E, Tomanin R, Friso A, Modena N, Tiso N, Scarpa M, Argenton F
Matrix biology : journal of the International Society for Matrix Biology29(1)43-50(2010 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data demonstrate that iduronate sulfatase plays a critical role during early vertebrate development and its downregulation may be responsible for severe developmental defects, including a misshapen trunk and abnormal craniofacial cartilages.
Title: A novel functional role of iduronate-2-sulfatase in zebrafish early development.

The following ids gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ids cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa34420	NM_001080068.1 Latest version!	Danio rerio iduronate 2-sulfatase (ids), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00
ODa43207	XM_009291036.2 Latest version!	Danio rerio iduronate 2-sulfatase (ids), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ids ( NM_001080068.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001073537.1 Danio rerio iduronate 2-sulfatase (ids), mRNA.

Price & Availability↑

CloneID	ODa34420
Clone ID Related Accession (Same CDS sequence)	NM_001080068.1
Accession Version	NM_001080068.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1686bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Danio rerio(zebrafish)
Product	iduronate 2-sulfatase precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC128823.1. On May 28, 2011 this sequence version replaced NM_001080574.1. ##Evidence-Data-START## Transcript exon combination :: BC128823.1, BC142731.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##

ATGAATGTAA TGTTCGTATT TACGTGTTGG TGGTTTGTTT TTATTTTTCA CCTTTTGGGG 
CGAGATGTTT TTGCAGCAAA AAGCAAAAAT TTCAACGTTT TGTATTTAAT TGCTGACGAT 
CTGAGACCAA CTTTAGGCTG TTATTCTGAT CCAGTGGTCA AATCACCGAA CATCGATCAG 
CTTGCATCTT TGAGCGTAGT GTTTCATAAC GCATATGCAC AGCAAGCTGT TTGTGGACCT 
AGTAGAGTGT CTTTCCTAAC AAGTCGAAGA CCAGACACCA CCAAACTCTA CGATTTCAAC 
TCATACTGGA GAGTTCATGC TGGAAACTAC ACCACACTGC CTCAATACTT CAAGTCTAAT 
GGATACACCA CTTTATCAGT GGGCAAAGTC TTCCATCCTG GCATTGCCTC CAACCACTCG 
GATGATTACC CGTACAGCTG GTCTGTACCG CCGTATCATC CACCCTCTTT TGAATATGAA 
AAGAGGAAGG TTTGCAAAGA TAAAGACGGC ACGTTGCACA GTAACCTGCT GTGTCCCGTG 
AACGTGTCTG AAATGCCTCT AGGAACCCTT CCTGACATGG AGAACACAGA GGAGGCCATT 
CGACTCTTGC GCTCTATGAA GGGCTCACAA AAACCATTCT TCCTGTCTGT CGGCTTCTAT 
AAACCTCATA TTCCTTTCAG AATCCCACAG GAGTACCTAA AGCTCTATCC TATTGAGAAT 
ATGACGCTAG CTCCAGATCC AGATGTGCCT AAGAAACTTC CTGATGTGGC CTACAACCCC 
TGGACCGACA TCCGCAAGAG GGAAGACGTG CAGGCGTTAA ATCTGAGCTT CCCTTATGGC 
CCAATTCCTA AAGATTTTCA GTTGAGGATC CGCCAGCACT ACTTTGCCTC TGTGTCATAT 
GTAGATGCTC AAGTCGGAAA GATTCTACAA ACCCTTGATG ATGTCGGCTT GGCCAAGAAC 
ACTATAGTGG TGCTCAGCTC AGATCACGGT TGGTCATTAG GAGAGCATGG TGAATGGGCC 
AAATACAGCA ACTTTGATGT GGCCACCCGA GTACCATTGA TGGTGTATAA GGCAGGAGTG 
AGCTCCCGTC GCTCTCGGCC CGGGGCGAAG ACGTTTCCCT TCATCGATGT GTTTCAGGAC 
ACACGGGAGC ACTTTGGCAA AGGTAAGATT GTAAACAGTG TGGTGGAGTT GCTGGATGTT 
TTCCCCACCC TGGCGAATCT GGCCGGTCTC CCTTCTGTTC ACCACTGCCC CTCTCCGTCC 
TTCAAGATGG ATTTGTGCAC CGAGGGCTCA AACCTGGCTA ATCTGATCCG AAACCCCAAA 
CATCTCAACA GAGAAGCATA CTCATTCAGC CAGTATCCAC GACCCTCAGA CTCCATCCAG 
GAGAACTCCG ACCTCCCAAA CCTTGCCGAT ATCAGAATTA TGGGTTACTC TATTCGCTCT 
AATGATTACC GTTATACTTT ATGGGTGGGT TTTGACCCTT TGCACTGCAA GCCCAACATG 
ACTGAGATCC ATGCAGGTGA ACTGTACATC CTGACTGAAG ACCCGGGACA GGATAATAAC 
CTGTTTGATG AATTTGGACA TGCAGCGCTT TTGAATAAGT TTGGAACGAT GCCTTCGTGG 
ACGGAGAGTC TGAAGCAGCA TATGATGTAT TTCAGCAGTG GATTGAAATC AAAGGGGCTT 
TCGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001073537.1
CDS	68..1753
Translation	MNVMFVFTCWWFVFIFHLLGRDVFAAKSKNFNVLYLIADDLRPTLGCYSDPVVKSPNIDQLASLSVVFHNAYAQQAVCGPSRVSFLTSRRPDTTKLYDFNSYWRVHAGNYTTLPQYFKSNGYTTLSVGKVFHPGIASNHSDDYPYSWSVPPYHPPSFEYEKRKVCKDKDGTLHSNLLCPVNVSEMPLGTLPDMENTEEAIRLLRSMKGSQKPFFLSVGFYKPHIPFRIPQEYLKLYPIENMTLAPDPDVPKKLPDVAYNPWTDIRKREDVQALNLSFPYGPIPKDFQLRIRQHYFASVSYVDAQVGKILQTLDDVGLAKNTIVVLSSDHGWSLGEHGEWAKYSNFDVATRVPLMVYKAGVSSRRSRPGAKTFPFIDVFQDTREHFGKGKIVNSVVELLDVFPTLANLAGLPSVHHCPSPSFKMDLCTEGSNLANLIRNPKHLNREAYSFSQYPRPSDSIQENSDLPNLADIRIMGYSIRSNDYRYTLWVGFDPLHCKPNMTEIHAGELYILTEDPGQDNNLFDEFGHAALLNKFGTMPSWTESLKQHMMYFSSGLKSKGLS

Target ORF information:

RefSeq Version	NM_001080068.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio iduronate 2-sulfatase (ids), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001080068.1

ORF Insert Sequence:

ATGAATGTAA TGTTCGTATT TACGTGTTGG TGGTTTGTTT TTATTTTTCA CCTTTTGGGG 
CGAGATGTTT TTGCAGCAAA AAGCAAAAAT TTCAACGTTT TGTATTTAAT TGCTGACGAT 
CTGAGACCAA CTTTAGGCTG TTATTCTGAT CCAGTGGTCA AATCACCGAA CATCGATCAG 
CTTGCATCTT TGAGCGTAGT GTTTCATAAC GCATATGCAC AGCAAGCTGT TTGTGGACCT 
AGTAGAGTGT CTTTCCTAAC AAGTCGAAGA CCAGACACCA CCAAACTCTA CGATTTCAAC 
TCATACTGGA GAGTTCATGC TGGAAACTAC ACCACACTGC CTCAATACTT CAAGTCTAAT 
GGATACACCA CTTTATCAGT GGGCAAAGTC TTCCATCCTG GCATTGCCTC CAACCACTCG 
GATGATTACC CGTACAGCTG GTCTGTACCG CCGTATCATC CACCCTCTTT TGAATATGAA 
AAGAGGAAGG TTTGCAAAGA TAAAGACGGC ACGTTGCACA GTAACCTGCT GTGTCCCGTG 
AACGTGTCTG AAATGCCTCT AGGAACCCTT CCTGACATGG AGAACACAGA GGAGGCCATT 
CGACTCTTGC GCTCTATGAA GGGCTCACAA AAACCATTCT TCCTGTCTGT CGGCTTCTAT 
AAACCTCATA TTCCTTTCAG AATCCCACAG GAGTACCTAA AGCTCTATCC TATTGAGAAT 
ATGACGCTAG CTCCAGATCC AGATGTGCCT AAGAAACTTC CTGATGTGGC CTACAACCCC 
TGGACCGACA TCCGCAAGAG GGAAGACGTG CAGGCGTTAA ATCTGAGCTT CCCTTATGGC 
CCAATTCCTA AAGATTTTCA GTTGAGGATC CGCCAGCACT ACTTTGCCTC TGTGTCATAT 
GTAGATGCTC AAGTCGGAAA GATTCTACAA ACCCTTGATG ATGTCGGCTT GGCCAAGAAC 
ACTATAGTGG TGCTCAGCTC AGATCACGGT TGGTCATTAG GAGAGCATGG TGAATGGGCC 
AAATACAGCA ACTTTGATGT GGCCACCCGA GTACCATTGA TGGTGTATAA GGCAGGAGTG 
AGCTCCCGTC GCTCTCGGCC CGGGGCGAAG ACGTTTCCCT TCATCGATGT GTTTCAGGAC 
ACACGGGAGC ACTTTGGCAA AGGTAAGATT GTAAACAGTG TGGTGGAGTT GCTGGATGTT 
TTCCCCACCC TGGCGAATCT GGCCGGTCTC CCTTCTGTTC ACCACTGCCC CTCTCCGTCC 
TTCAAGATGG ATTTGTGCAC CGAGGGCTCA AACCTGGCTA ATCTGATCCG AAACCCCAAA 
CATCTCAACA GAGAAGCATA CTCATTCAGC CAGTATCCAC GACCCTCAGA CTCCATCCAG 
GAGAACTCCG ACCTCCCAAA CCTTGCCGAT ATCAGAATTA TGGGTTACTC TATTCGCTCT 
AATGATTACC GTTATACTTT ATGGGTGGGT TTTGACCCTT TGCACTGCAA GCCCAACATG 
ACTGAGATCC ATGCAGGTGA ACTGTACATC CTGACTGAAG ACCCGGGACA GGATAATAAC 
CTGTTTGATG AATTTGGACA TGCAGCGCTT TTGAATAAGT TTGGAACGAT GCCTTCGTGG 
ACGGAGAGTC TGAAGCAGCA TATGATGTAT TTCAGCAGTG GATTGAAATC AAAGGGGCTT 
TCGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ids ( XM_009291036.2 ) cDNA ORF clone, Danio rerio(zebrafish) -> XP_009289311.1 Danio rerio iduronate 2-sulfatase (ids), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ODa43207
Clone ID Related Accession (Same CDS sequence)	XM_009291036.2
Accession Version	XM_009291036.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 966bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-23
Organism	Danio rerio(Zebrafish)
Product	iduronate 2-sulfatase isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_007125.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 24, 2016 this sequence version replaced XM_009291036.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Danio rerio Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACGCTAG CTCCAGATCC AGATGTGCCT AAGAAACTTC CTGATGTGGC CTACAACCCC 
TGGACCGACA TCCGCAAGAG GGAAGACGTG CAGGCGTTAA ATCTGAGCTT CCCTTATGGC 
CCAATTCCTA AAGATTTTCA GTTGAGGATC CGCCAGCACT ACTTTGCCTC TGTGTCATAT 
GTAGATGCTC AAGTCGGAAA GATTCTACAA ACCCTTGATG ATGTCGGCTT GGCCAAGAAC 
ACTATAGTGG TGCTCAGCTC AGATCACGGT TGGTCATTAG GAGAGCATGG TGAATGGGCC 
AAATACAGCA ACTTTGATGT GGCCACCCGA GTACCATTGA TGGTGTATAA GGCAGGAGTG 
AGCTCCCGTC GCTCTCGGAC CGGGGCGAAG ACGTTTCCCT TCATCGATGT GTTTCAGGAC 
ACACGGGAGC ACTTTGGCAA AGGTAAGATT GTAAACAGTG TGGTGGAGTT GCTGGATGTT 
TTCCCCACCC TGGCGAATCT GGCCGGTCTC CCTTCTGTTC ACCACTGCCC CTCTCCGTCC 
TTCAAGATGG ATTTGTGCAC CGAGGGCTCA AACCTGGCTA ATCTGATCCG AAACCCCAAA 
CATCTCAACA GAGAAGCATA CTCATTCAGC CAGTATCCAC GACCCTCAGA CTCCATTCAG 
GAGAACTCCG ACCTCCCAAA CCTTGCCGAT ATCAGAATTA TGGGTTACTC TATTCGCTCT 
AATGATTACC GTTATACTTT ATGGGTGGGT TTTGACCCTC TGCACTGCAA GCCCAACATG 
ACGGAGATCC ATGCAGGTGA ACTGTACATC CTGACTGAAG ACCCGGGACA AGATAATAAC 
CTGTTTGATG AATTTGGACA CGCAGCACTT TTGAATAAGT TTGGAACGAT GCCTTCGTGG 
ACGGAGAGTC TGAAGCAGCA TATGATGTAT TTCAGCAGTG GATGGAAATC AAAGGGGCTT 
TCGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_009289311.1
CDS	125..1090
Translation	MTLAPDPDVPKKLPDVAYNPWTDIRKREDVQALNLSFPYGPIPKDFQLRIRQHYFASVSYVDAQVGKILQTLDDVGLAKNTIVVLSSDHGWSLGEHGEWAKYSNFDVATRVPLMVYKAGVSSRRSRTGAKTFPFIDVFQDTREHFGKGKIVNSVVELLDVFPTLANLAGLPSVHHCPSPSFKMDLCTEGSNLANLIRNPKHLNREAYSFSQYPRPSDSIQENSDLPNLADIRIMGYSIRSNDYRYTLWVGFDPLHCKPNMTEIHAGELYILTEDPGQDNNLFDEFGHAALLNKFGTMPSWTESLKQHMMYFSSGWKSKGLS

Target ORF information:

RefSeq Version	XM_009291036.2
Organism	Danio rerio(Zebrafish)
Definition	Danio rerio iduronate 2-sulfatase (ids), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_009291036.2

ORF Insert Sequence:

ATGACGCTAG CTCCAGATCC AGATGTGCCT AAGAAACTTC CTGATGTGGC CTACAACCCC 
TGGACCGACA TCCGCAAGAG GGAAGACGTG CAGGCGTTAA ATCTGAGCTT CCCTTATGGC 
CCAATTCCTA AAGATTTTCA GTTGAGGATC CGCCAGCACT ACTTTGCCTC TGTGTCATAT 
GTAGATGCTC AAGTCGGAAA GATTCTACAA ACCCTTGATG ATGTCGGCTT GGCCAAGAAC 
ACTATAGTGG TGCTCAGCTC AGATCACGGT TGGTCATTAG GAGAGCATGG TGAATGGGCC 
AAATACAGCA ACTTTGATGT GGCCACCCGA GTACCATTGA TGGTGTATAA GGCAGGAGTG 
AGCTCCCGTC GCTCTCGGAC CGGGGCGAAG ACGTTTCCCT TCATCGATGT GTTTCAGGAC 
ACACGGGAGC ACTTTGGCAA AGGTAAGATT GTAAACAGTG TGGTGGAGTT GCTGGATGTT 
TTCCCCACCC TGGCGAATCT GGCCGGTCTC CCTTCTGTTC ACCACTGCCC CTCTCCGTCC 
TTCAAGATGG ATTTGTGCAC CGAGGGCTCA AACCTGGCTA ATCTGATCCG AAACCCCAAA 
CATCTCAACA GAGAAGCATA CTCATTCAGC CAGTATCCAC GACCCTCAGA CTCCATTCAG 
GAGAACTCCG ACCTCCCAAA CCTTGCCGAT ATCAGAATTA TGGGTTACTC TATTCGCTCT 
AATGATTACC GTTATACTTT ATGGGTGGGT TTTGACCCTC TGCACTGCAA GCCCAACATG 
ACGGAGATCC ATGCAGGTGA ACTGTACATC CTGACTGAAG ACCCGGGACA AGATAATAAC 
CTGTTTGATG AATTTGGACA CGCAGCACTT TTGAATAAGT TTGGAACGAT GCCTTCGTGG 
ACGGAGAGTC TGAAGCAGCA TATGATGTAT TTCAGCAGTG GATGGAAATC AAAGGGGCTT 
TCGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Perturbations in cell signaling elicit early cardiac defects in mucopolysaccharidosis type II.
Human molecular genetics26(9)1643-1655(2017 05)
Costa R,Urbani A,Salvalaio M,Bellesso S,Cieri D,Zancan I,Filocamo M,Bonaldo P,Szab? I,Tomanin R,Moro E

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

A novel functional role of iduronate-2-sulfatase in zebrafish early development.
Matrix biology : journal of the International Society for Matrix Biology29(1)43-50(2010 Jan)
Moro E,Tomanin R,Friso A,Modena N,Tiso N,Scarpa M,Argenton F

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ids cDNA ORF clone, Danio rerio(zebrafish)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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