KCNQ1 cDNA ORF clone, Danio rerio(Zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	KCNQ1
Entrez Gene ID	557498
Full Name	potassium voltage-gated channel, KQT-like subfamily, member 1
Synonyms	zgc:158384
General protein information	Preferred Names potassium voltage-gated channel, KQT-like subfamily, member 1 Names potassium voltage-gated channel subfamily KQT member 1 potassium voltage-gated channel, subfamily Q, member 1
Gene Type	protein-coding
Organism	Danio rerio(Zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
XM_005166469.4	XP_005166526.1	potassium voltage-gated channel subfamily KQT member 1 isoform X1
NM_001123242.2	NP_001116714.1	potassium voltage-gated channel subfamily KQT member 1
XM_005166469.3	XP_005166526.1	potassium voltage-gated channel subfamily KQT member 1 isoform X1

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Kcnq1	NP_032460.2
Rattus norvegicus (Norway rat)	Kcnq1	NP_114462.1
Gallus gallus (chicken)	KCNQ1	XP_421022.3
Caenorhabditis elegans (roundworm)	kqt-3	NP_001254404.1
Xenopus tropicalis (tropical clawed frog)	kcnq1	XP_002936545.2
Homo sapiens (human)	KCNQ1	NP_000209.2
Pan troglodytes (chimpanzee)	KCNQ1	XP_003312922.2
Danio rerio (zebrafish)	kcnq1	NP_001116714.1
Bos taurus (cattle)	KCNQ1	NP_001192370.1
Canis lupus familiaris (dog)	KCNQ1	XP_005631798.1

Gene Ontology
Bibliography

Related articles in PubMed

Coordinated Expression of Two Types of Low-Threshold K
Watanabe T, Shimazaki T, Oda Y
eNeuro4(5)(2017 Sep-Oct)

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y, Bobe J
BMC genomics17368(2016 05)

Assignment of Functional Relevance to Genes at Type 2 Diabetes-Associated Loci Through Investigation of ?-Cell Mass Deficits.
O'Hare EA, Yerges-Armstrong LM, Perry JA, Shuldiner AR, Zaghloul NA
Molecular endocrinology (Baltimore, Md.)30(4)429-45(2016 Apr)

Kcnq1-5 (Kv7.1-5) potassium channel expression in the adult zebrafish.
Wu C, Sharma K, Laster K, Hersi M, Torres C, Lukas TJ, Moore EJ
BMC physiology141(2014 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following KCNQ1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KCNQ1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ODa04398	NM_001123242.2 Latest version!	Danio rerio potassium voltage-gated channel, KQT-like subfamily, member 1.1 (kcnq1.1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00
ODa13382	XM_005166469.4 Latest version!	Danio rerio potassium voltage-gated channel, KQT-like subfamily, member 1 (kcnq1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00
View Old Accession Versions >>
ODa13382	XM_005166469.3	Danio rerio potassium voltage-gated channel, KQT-like subfamily, member 1 (kcnq1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

KCNQ1 ( NM_001123242.2 ) cDNA ORF clone, Danio rerio(Zebrafish) -> NP_001116714.1 Danio rerio potassium voltage-gated channel, KQT-like subfamily, member 1.1 (kcnq1.1), mRNA.

Price & Availability↑

CloneID	ODa04398
Clone ID Related Accession (Same CDS sequence)	NM_001123242.2
Accession Version	NM_001123242.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1968bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-07
Organism	Danio rerio(zebrafish)
Product	potassium voltage-gated channel subfamily KQT member 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AL928843.9. On or before May 19, 2009 this sequence version replaced NM_001080566.1, NM_001123242.1. ##Evidence-Data-START## Transcript exon combination :: GFIL01013846.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN02951650, SAMN06350656 [ECO:0000348] ##Evidence-Data-END##

ATGACCTCCC CAGCTCACAG TACAGCCACC GAGGCTTCAT GGACTGCTGG AGCCGCAGAC 
CTGCAGATGA CCGAGGCTCT GCACCTGCGG AATGACGGCG TGCGCTTCCC CTCCTCGGTG 
CCCGTGGATC CGGCGGTGAT CACGCAGCAC CCGCCGTCTC ACCTCCATCC CCGCATGTCC 
GTGTACAGCG CCACACGCCC CACACTCTCC AGGTCCTTCC TTCAAGGACG TGTTTATAAT 
TTCTTGGAGA GACCCACGGG TTGGAAATGC TTTGTGTATC ATTTTACAGT ATTCCTCATT 
GTGCTTTCCT GCCTGATCCT CAGTGTGCTG TCCACCATCG ACGAGTATCA AGCACTGGCT 
AATAAAACAC TATTCTGGAT GGAATTAGTG CTGGTAATGT TCTTTGGTGT GGAGTACGTG 
GTCCGTCTGT GGTCAGCTGG ATGCCGGAGT AAATATGTGG GAATTCTGGG CAGGCTTCGC 
TTTGCCCGAA AGCCAATTTC TGTTATTGAC CTGATTGTGG TGGTGGCTTC TATTATAGTA 
TTGGCATTTG GCTCTAATGG CCAGGTATTT GCTACCTCTG CTGTCAGAGG AGTCCGCTTC 
CTTCAAATTC TGCGAATGCT GCATGTGGAT CGACAAGGTG GAACATGGCG GTTGCTTGGA 
TCAGTAGTGT TTATACATCG ACAGGAACTG ATCACAACTC TCTATATCGG ATTCCTGGGG 
CTCATCTTCT CCTCCTACTT TGTGTATCTG GCAGAGAAGG ATGCGGTGGA TGACCACGGC 
AACTCTGGGT TTGGCAGCTA CGCCGATGCT CTGTGGTGGG GTGTGGTAAC AGTAACCACT 
ATTGGCTACG GAGACAAGGT TCCTCAGACT TGGATAGGAA AGACTATTGC ATCATGTTTC 
TCTGTCTTCG CTATCTCCTT TTTTGCCCTC CCTGCAGGAA TCCTGGGCTC CGGTTTTGCT 
CTGAAGGTAC AGCAGAAACA GAGACAAAAA CATTTCAACA GGCAAATTCC TGCAGCTGCG 
AGTCTCATAC AGGCGTCCTG GAGGTGTTTC GCCTTGCTGA ACCCTGATTC TGCCACATAC 
AAGTTATTTG TGAAACGAAA TCTCAGCAGT TCAGGGTCTA GCCCTAAATT AAAGGTGAAG 
ATGAGGAGGA AAATGAAGAT TAGTGACCGG AATAACGGGC AGAATTCTCC TGCAGTACCT 
TCCATAACCT ATGACTCCTT TGATGATGGG AGGGACAGCA GGCAAGAGAC ACTGACCAGT 
CTTCAACAGT CAGTCATCTC AGATGGGACA AACACAACCA GAAGATATGA ACGAGCGCCG 
TCCTGGAACT CTCTGTCCTC GTTCCAGTTC TCCACACCTC CAGCCACGAA GCCTGGGGTT 
TTCGAGGTCT CATCTCGGCC CACGCTTCAG AGGAGCAGCA GCATTGCAGA TGATATGGAG 
ACTGAGCCGG AGCGAGAGAT TGTGCTCATT CCAGTCGCTC ATGTGTCTCA GTTGCGGGAT 
TCTCATCGAG CAGCCATCCG TGTGATCCAG AGAATGTACT ACTTTGTGGC CAGAAAGAAG 
TTTCAGCAAG CACGTAAGCC ATATGATGTG CGTGACGTCA TTGAGCAGTA TTCACAGGGC 
CATCTCAACC TCATGGTGCG CATCAAGGAG CTGCAAAGAA GACTGGATCA CTCTTTAGGG 
AAGCAGTCCC TTTTCCAGAC AAGTTCAGAG CGCTTGAAAG ACAAAGGCAC AAACACTATT 
GGCTCCAGAC TCAACAGAAT GGATGAGAAG ATCACACACA TGGACAGGAC CCTCAACAGC 
ATTGCTGAGT CGCTCAACCT CATGCTGGCG AGGGAGAGAC GGGGGGATCT GGCCAGGGGG 
AAGGAGCAGC GAAGCACCAT GCGCCGACAG TCAGCCACGT TCAGCCTGTC AGTGCTGGAC 
AGCAGCGAGC AACTGTCCAC AACAACTGCT ATTCATGAGG ACAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001116714.1
CDS	1..1968
Translation	MTSPAHSTATEASWTAGAADLQMTEALHLRNDGVRFPSSVPVDPAVITQHPPSHLHPRMSVYSATRPTLSRSFLQGRVYNFLERPTGWKCFVYHFTVFLIVLSCLILSVLSTIDEYQALANKTLFWMELVLVMFFGVEYVVRLWSAGCRSKYVGILGRLRFARKPISVIDLIVVVASIIVLAFGSNGQVFATSAVRGVRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVDDHGNSGFGSYADALWWGVVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQASWRCFALLNPDSATYKLFVKRNLSSSGSSPKLKVKMRRKMKISDRNNGQNSPAVPSITYDSFDDGRDSRQETLTSLQQSVISDGTNTTRRYERAPSWNSLSSFQFSTPPATKPGVFEVSSRPTLQRSSSIADDMETEPEREIVLIPVAHVSQLRDSHRAAIRVIQRMYYFVARKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDHSLGKQSLFQTSSERLKDKGTNTIGSRLNRMDEKITHMDRTLNSIAESLNLMLARERRGDLARGKEQRSTMRRQSATFSLSVLDSSEQLSTTTAIHEDS

Target ORF information:

RefSeq Version	NM_001123242.2
Organism	Danio rerio(zebrafish)
Definition	Danio rerio potassium voltage-gated channel, KQT-like subfamily, member 1.1 (kcnq1.1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001123242.2

ORF Insert Sequence:

ATGACCTCCC CAGCTCACAG TACAGCCACC GAGGCTTCAT GGACTGCTGG AGCCGCAGAC 
CTGCAGATGA CCGAGGCTCT GCACCTGCGG AATGACGGCG TGCGCTTCCC CTCCTCGGTG 
CCCGTGGATC CGGCGGTGAT CACGCAGCAC CCGCCGTCTC ACCTCCATCC CCGCATGTCC 
GTGTACAGCG CCACACGCCC CACACTCTCC AGGTCCTTCC TTCAAGGACG TGTTTATAAT 
TTCTTGGAGA GACCCACGGG TTGGAAATGC TTTGTGTATC ATTTTACAGT ATTCCTCATT 
GTGCTTTCCT GCCTGATCCT CAGTGTGCTG TCCACCATCG ACGAGTATCA AGCACTGGCT 
AATAAAACAC TATTCTGGAT GGAATTAGTG CTGGTAATGT TCTTTGGTGT GGAGTACGTG 
GTCCGTCTGT GGTCAGCTGG ATGCCGGAGT AAATATGTGG GAATTCTGGG CAGGCTTCGC 
TTTGCCCGAA AGCCAATTTC TGTTATTGAC CTGATTGTGG TGGTGGCTTC TATTATAGTA 
TTGGCATTTG GCTCTAATGG CCAGGTATTT GCTACCTCTG CTGTCAGAGG AGTCCGCTTC 
CTTCAAATTC TGCGAATGCT GCATGTGGAT CGACAAGGTG GAACATGGCG GTTGCTTGGA 
TCAGTAGTGT TTATACATCG ACAGGAACTG ATCACAACTC TCTATATCGG ATTCCTGGGG 
CTCATCTTCT CCTCCTACTT TGTGTATCTG GCAGAGAAGG ATGCGGTGGA TGACCACGGC 
AACTCTGGGT TTGGCAGCTA CGCCGATGCT CTGTGGTGGG GTGTGGTAAC AGTAACCACT 
ATTGGCTACG GAGACAAGGT TCCTCAGACT TGGATAGGAA AGACTATTGC ATCATGTTTC 
TCTGTCTTCG CTATCTCCTT TTTTGCCCTC CCTGCAGGAA TCCTGGGCTC CGGTTTTGCT 
CTGAAGGTAC AGCAGAAACA GAGACAAAAA CATTTCAACA GGCAAATTCC TGCAGCTGCG 
AGTCTCATAC AGGCGTCCTG GAGGTGTTTC GCCTTGCTGA ACCCTGATTC TGCCACATAC 
AAGTTATTTG TGAAACGAAA TCTCAGCAGT TCAGGGTCTA GCCCTAAATT AAAGGTGAAG 
ATGAGGAGGA AAATGAAGAT TAGTGACCGG AATAACGGGC AGAATTCTCC TGCAGTACCT 
TCCATAACCT ATGACTCCTT TGATGATGGG AGGGACAGCA GGCAAGAGAC ACTGACCAGT 
CTTCAACAGT CAGTCATCTC AGATGGGACA AACACAACCA GAAGATATGA ACGAGCGCCG 
TCCTGGAACT CTCTGTCCTC GTTCCAGTTC TCCACACCTC CAGCCACGAA GCCTGGGGTT 
TTCGAGGTCT CATCTCGGCC CACGCTTCAG AGGAGCAGCA GCATTGCAGA TGATATGGAG 
ACTGAGCCGG AGCGAGAGAT TGTGCTCATT CCAGTCGCTC ATGTGTCTCA GTTGCGGGAT 
TCTCATCGAG CAGCCATCCG TGTGATCCAG AGAATGTACT ACTTTGTGGC CAGAAAGAAG 
TTTCAGCAAG CACGTAAGCC ATATGATGTG CGTGACGTCA TTGAGCAGTA TTCACAGGGC 
CATCTCAACC TCATGGTGCG CATCAAGGAG CTGCAAAGAA GACTGGATCA CTCTTTAGGG 
AAGCAGTCCC TTTTCCAGAC AAGTTCAGAG CGCTTGAAAG ACAAAGGCAC AAACACTATT 
GGCTCCAGAC TCAACAGAAT GGATGAGAAG ATCACACACA TGGACAGGAC CCTCAACAGC 
ATTGCTGAGT CGCTCAACCT CATGCTGGCG AGGGAGAGAC GGGGGGATCT GGCCAGGGGG 
AAGGAGCAGC GAAGCACCAT GCGCCGACAG TCAGCCACGT TCAGCCTGTC AGTGCTGGAC 
AGCAGCGAGC AACTGTCCAC AACAACTGCT ATTCATGAGG ACAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KCNQ1 ( XM_005166469.4 ) cDNA ORF clone, Danio rerio(Zebrafish) -> XP_005166526.1 Danio rerio potassium voltage-gated channel, KQT-like subfamily, member 1 (kcnq1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ODa13382
Clone ID Related Accession (Same CDS sequence)	XM_005166469.4 , XM_005166469.3
Accession Version	XM_005166469.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1932bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-06-14
Organism	Danio rerio(zebrafish)
Product	potassium voltage-gated channel subfamily KQT member 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_007118.7) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 15, 2017 this sequence version replaced XM_005166469.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Danio rerio Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACCTCCC CAGCTCACAG TACAGCCACC GAGGCTTCAT GGACTGCTGG AGCCGCAGAC 
CTGCAGATGA CCGAGGCTCT GCACCTGCGG AATGACGGCG TGCGCTTCCC CTCCTCGGTG 
CCCGTGGATC CGGCGGTGAT CACGCAGCAC CCGCCGTCTC ACCTCCATCC CCGCATGTCC 
GTGTACAGCG CCACACGCCC CACACTCTCC AGGTCCTTCC TTCAAGGACG TGTTTATAAT 
TTCTTGGAGA GACCCACGGG TTGGAAATGC TTTGTGTATC ATTTTACAGT ATTCCTCATT 
GTGCTTTCCT GCCTGATCCT CAGTGTGCTG TCCACCATCG ACGAGTATCA AGCACTGGCT 
AATAAAACAC TATTCTGGAT GGAATTAGTG CTGGTAATGT TCTTTGGTGT GGAGTACGTG 
GTCCGTCTGT GGTCAGCTGG ATGCCGGAGT AAATATGTGG GAATTCTGGG CAGGCTTCGC 
TTTGCCCGAA AGCCAATTTC TGTTATTGAC CTGATTGTGG TGGTGGCTTC TATTATAGTA 
TTGGCATTTG GCTCTAATGG CCAGGTATTT GCTACCTCTG CTGTCAGAGG AGTCCGCTTC 
CTTCAAATTC TGCGAATGCT GCATGTGGAT CGACAAGGTG GAACATGGCG GTTGCTTGGA 
TCAGTAGTGT TTATACATCG ACAGGAACTG ATCACAACTC TCTATATCGG ATTCCTGGGG 
CTCATCTTCT CCTCCTACTT TGTGTATCTG GCAGAGAAGG ATGCGGTGGA TGACCACGGC 
AACTCTGGGT TTGGCAGCTA CGCCGATGCT CTGTGGTGGG GTGTGGTAAC AGTAACCACT 
ATTGGCTACG GAGACAAGGT TCCTCAGACT TGGATAGGAA AGACTATTGC ATCATGTTTC 
TCTGTCTTCG CTATCTCCTT TTTTGCCCTC CCTGCAGGAA TCCTGGGCTC CGGTTTTGCT 
CTGAAGGTAC AGCAGAAACA GAGACAAAAA CATTTCAACA GGCAAATTCC TGCAGCTGCG 
AGTCTCATAC AGGCGTCCTG GAGGTGTTTC GCCTTGCTGA ACCCTGATTC TGCCACATAC 
AAGTTATTTG TGAAACGAAA TCTCAGCAGT TCAGGGTCTA GCCCTAAATT AAAGGTGAAG 
ATGAGGAGGA AAATGAAGAT TAGTGACCGG AATAACGGGC AGAATTCTCC TGCAGTACCT 
TCCATAACCT ATGACTCCTT TGATGATGGG AGGGACAGCA GGCAAGAGAC ACTGACCAGT 
CTTCAACAGT CAGAACGAGC GCCGTCCTGG AACTCTCTGT CCTCGTTCCA GTTCTCCACA 
CCTCCAGCCA CGAAGCCTGG GGTTTTCGAG GTCTCATCTC GGCCCACGCT TCAGAGGAGC 
AGCAGCATTG CAGATGATAT GGAGACTGAG CCGGAGCGAG AGATTGTGCT CATTCCAGTC 
GCTCATGTGT CTCAGTTGCG GGATTCTCAT CGAGCAGCCA TCCGTGTGAT CCAGAGAATG 
TACTACTTTG TGGCCAGAAA GAAGTTTCAG CAAGCACGTA AGCCATATGA TGTGCGTGAC 
GTCATTGAGC AGTATTCACA GGGCCATCTC AACCTCATGG TGCGCATCAA GGAGCTGCAA 
AGAAGACTGG ATCACTCTTT AGGGAAGCAG TCCCTTTTCC AGACAAGTTC AGAGCGCTTG 
AAAGACAAAG GCACAAACAC TATTGGCTCC AGACTCAACA GAATGGATGA GAAGATCACA 
CACATGGACA GGACCCTCAA CAGCATTGCT GAGTCGCTCA ACCTCATGCT GGCGAGGGAG 
AGACGGGGGG ATCTGGCCAG GGGGAAGGAG CAGCGAAGCA CCATGCGCCG ACAGTCAGCC 
ACGTTCAGCC TGTCAGTGCT GGACAGCAGC GAGCAACTGT CCACAACAAC TGCTATTCAT 
GAGGACAGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005166526.1
CDS	363..2294
Translation	MTSPAHSTATEASWTAGAADLQMTEALHLRNDGVRFPSSVPVDPAVITQHPPSHLHPRMSVYSATRPTLSRSFLQGRVYNFLERPTGWKCFVYHFTVFLIVLSCLILSVLSTIDEYQALANKTLFWMELVLVMFFGVEYVVRLWSAGCRSKYVGILGRLRFARKPISVIDLIVVVASIIVLAFGSNGQVFATSAVRGVRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVDDHGNSGFGSYADALWWGVVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQASWRCFALLNPDSATYKLFVKRNLSSSGSSPKLKVKMRRKMKISDRNNGQNSPAVPSITYDSFDDGRDSRQETLTSLQQSERAPSWNSLSSFQFSTPPATKPGVFEVSSRPTLQRSSSIADDMETEPEREIVLIPVAHVSQLRDSHRAAIRVIQRMYYFVARKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDHSLGKQSLFQTSSERLKDKGTNTIGSRLNRMDEKITHMDRTLNSIAESLNLMLARERRGDLARGKEQRSTMRRQSATFSLSVLDSSEQLSTTTAIHEDS

Target ORF information:

RefSeq Version	XM_005166469.4
Organism	Danio rerio(zebrafish)
Definition	Danio rerio potassium voltage-gated channel, KQT-like subfamily, member 1 (kcnq1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005166469.4

ORF Insert Sequence:

ATGACCTCCC CAGCTCACAG TACAGCCACC GAGGCTTCAT GGACTGCTGG AGCCGCAGAC 
CTGCAGATGA CCGAGGCTCT GCACCTGCGG AATGACGGCG TGCGCTTCCC CTCCTCGGTG 
CCCGTGGATC CGGCGGTGAT CACGCAGCAC CCGCCGTCTC ACCTCCATCC CCGCATGTCC 
GTGTACAGCG CCACACGCCC CACACTCTCC AGGTCCTTCC TTCAAGGACG TGTTTATAAT 
TTCTTGGAGA GACCCACGGG TTGGAAATGC TTTGTGTATC ATTTTACAGT ATTCCTCATT 
GTGCTTTCCT GCCTGATCCT CAGTGTGCTG TCCACCATCG ACGAGTATCA AGCACTGGCT 
AATAAAACAC TATTCTGGAT GGAATTAGTG CTGGTAATGT TCTTTGGTGT GGAGTACGTG 
GTCCGTCTGT GGTCAGCTGG ATGCCGGAGT AAATATGTGG GAATTCTGGG CAGGCTTCGC 
TTTGCCCGAA AGCCAATTTC TGTTATTGAC CTGATTGTGG TGGTGGCTTC TATTATAGTA 
TTGGCATTTG GCTCTAATGG CCAGGTATTT GCTACCTCTG CTGTCAGAGG AGTCCGCTTC 
CTTCAAATTC TGCGAATGCT GCATGTGGAT CGACAAGGTG GAACATGGCG GTTGCTTGGA 
TCAGTAGTGT TTATACATCG ACAGGAACTG ATCACAACTC TCTATATCGG ATTCCTGGGG 
CTCATCTTCT CCTCCTACTT TGTGTATCTG GCAGAGAAGG ATGCGGTGGA TGACCACGGC 
AACTCTGGGT TTGGCAGCTA CGCCGATGCT CTGTGGTGGG GTGTGGTAAC AGTAACCACT 
ATTGGCTACG GAGACAAGGT TCCTCAGACT TGGATAGGAA AGACTATTGC ATCATGTTTC 
TCTGTCTTCG CTATCTCCTT TTTTGCCCTC CCTGCAGGAA TCCTGGGCTC CGGTTTTGCT 
CTGAAGGTAC AGCAGAAACA GAGACAAAAA CATTTCAACA GGCAAATTCC TGCAGCTGCG 
AGTCTCATAC AGGCGTCCTG GAGGTGTTTC GCCTTGCTGA ACCCTGATTC TGCCACATAC 
AAGTTATTTG TGAAACGAAA TCTCAGCAGT TCAGGGTCTA GCCCTAAATT AAAGGTGAAG 
ATGAGGAGGA AAATGAAGAT TAGTGACCGG AATAACGGGC AGAATTCTCC TGCAGTACCT 
TCCATAACCT ATGACTCCTT TGATGATGGG AGGGACAGCA GGCAAGAGAC ACTGACCAGT 
CTTCAACAGT CAGAACGAGC GCCGTCCTGG AACTCTCTGT CCTCGTTCCA GTTCTCCACA 
CCTCCAGCCA CGAAGCCTGG GGTTTTCGAG GTCTCATCTC GGCCCACGCT TCAGAGGAGC 
AGCAGCATTG CAGATGATAT GGAGACTGAG CCGGAGCGAG AGATTGTGCT CATTCCAGTC 
GCTCATGTGT CTCAGTTGCG GGATTCTCAT CGAGCAGCCA TCCGTGTGAT CCAGAGAATG 
TACTACTTTG TGGCCAGAAA GAAGTTTCAG CAAGCACGTA AGCCATATGA TGTGCGTGAC 
GTCATTGAGC AGTATTCACA GGGCCATCTC AACCTCATGG TGCGCATCAA GGAGCTGCAA 
AGAAGACTGG ATCACTCTTT AGGGAAGCAG TCCCTTTTCC AGACAAGTTC AGAGCGCTTG 
AAAGACAAAG GCACAAACAC TATTGGCTCC AGACTCAACA GAATGGATGA GAAGATCACA 
CACATGGACA GGACCCTCAA CAGCATTGCT GAGTCGCTCA ACCTCATGCT GGCGAGGGAG 
AGACGGGGGG ATCTGGCCAG GGGGAAGGAG CAGCGAAGCA CCATGCGCCG ACAGTCAGCC 
ACGTTCAGCC TGTCAGTGCT GGACAGCAGC GAGCAACTGT CCACAACAAC TGCTATTCAT 
GAGGACAGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KCNQ1 ( XM_005166469.3 ) cDNA ORF clone, Danio rerio(Zebrafish) -> XP_005166526.1 Danio rerio potassium voltage-gated channel, KQT-like subfamily, member 1 (kcnq1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ODa13382
Clone ID Related Accession (Same CDS sequence)	XM_005166469.4 , XM_005166469.3
Accession Version	XM_005166469.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1932bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-23
Organism	Danio rerio(Zebrafish)
Product	potassium voltage-gated channel subfamily KQT member 1 isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_007118.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 24, 2016 this sequence version replaced XM_005166469.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Danio rerio Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACCTCCC CAGCTCACAG TACAGCCACC GAGGCTTCAT GGACTGCTGG AGCCGCAGAC 
CTGCAGATGA CCGAGGCTCT GCACCTGCGG AATGACGGCG TGCGCTTCCC CTCCTCGGTG 
CCCGTGGATC CGGCGGTGAT CACGCAGCAC CCGCCGTCTC ACCTCCATCC CCGCATGTCC 
GTGTACAGCG CCACACGCCC CACACTCTCC AGGTCCTTCC TTCAAGGACG TGTTTATAAT 
TTCTTGGAGA GACCCACGGG TTGGAAATGC TTTGTGTATC ATTTTACAGT ATTCCTCATT 
GTGCTTTCCT GCCTGATCCT CAGTGTGCTG TCCACCATCG ACGAGTATCA AGCACTGGCT 
AATAAAACAC TATTCTGGAT GGAATTAGTG CTGGTAATGT TCTTTGGTGT GGAGTACGTG 
GTCCGTCTGT GGTCAGCTGG ATGCCGGAGT AAATATGTGG GAATTCTGGG CAGGCTTCGC 
TTTGCCCGAA AGCCAATTTC TGTTATTGAC CTGATTGTGG TGGTGGCTTC TATTATAGTA 
TTGGCATTTG GCTCTAATGG CCAGGTATTT GCTACCTCTG CTGTCAGAGG AGTCCGCTTC 
CTTCAAATTC TGCGAATGCT GCATGTGGAT CGACAAGGTG GAACATGGCG GTTGCTTGGA 
TCAGTAGTGT TTATACATCG ACAGGAACTG ATCACAACTC TCTATATCGG ATTCCTGGGG 
CTCATCTTCT CCTCCTACTT TGTGTATCTG GCAGAGAAGG ATGCGGTGGA TGACCACGGC 
AACTCTGGGT TTGGCAGCTA CGCCGATGCT CTGTGGTGGG GTGTGGTAAC AGTAACCACT 
ATTGGCTACG GAGACAAGGT TCCTCAGACT TGGATAGGAA AGACTATTGC ATCATGTTTC 
TCTGTCTTCG CTATCTCCTT TTTTGCCCTC CCTGCAGGAA TCCTGGGCTC CGGTTTTGCT 
CTGAAGGTAC AGCAGAAACA GAGACAAAAA CATTTCAACA GGCAAATTCC TGCAGCTGCG 
AGTCTCATAC AGGCGTCCTG GAGGTGTTTC GCCTTGCTGA ACCCTGATTC TGCCACATAC 
AAGTTATTTG TGAAACGAAA TCTCAGCAGT TCAGGGTCTA GCCCTAAATT AAAGGTGAAG 
ATGAGGAGGA AAATGAAGAT TAGTGACCGG AATAACGGGC AGAATTCTCC TGCAGTACCT 
TCCATAACCT ATGACTCCTT TGATGATGGG AGGGACAGCA GGCAAGAGAC ACTGACCAGT 
CTTCAACAGT CAGAACGAGC GCCGTCCTGG AACTCTCTGT CCTCGTTCCA GTTCTCCACA 
CCTCCAGCCA CGAAGCCTGG GGTTTTCGAG GTCTCATCTC GGCCCACGCT TCAGAGGAGC 
AGCAGCATTG CAGATGATAT GGAGACTGAG CCGGAGCGAG AGATTGTGCT CATTCCAGTC 
GCTCATGTGT CTCAGTTGCG GGATTCTCAT CGAGCAGCCA TCCGTGTGAT CCAGAGAATG 
TACTACTTTG TGGCCAGAAA GAAGTTTCAG CAAGCACGTA AGCCATATGA TGTGCGTGAC 
GTCATTGAGC AGTATTCACA GGGCCATCTC AACCTCATGG TGCGCATCAA GGAGCTGCAA 
AGAAGACTGG ATCACTCTTT AGGGAAGCAG TCCCTTTTCC AGACAAGTTC AGAGCGCTTG 
AAAGACAAAG GCACAAACAC TATTGGCTCC AGACTCAACA GAATGGATGA GAAGATCACA 
CACATGGACA GGACCCTCAA CAGCATTGCT GAGTCGCTCA ACCTCATGCT GGCGAGGGAG 
AGACGGGGGG ATCTGGCCAG GGGGAAGGAG CAGCGAAGCA CCATGCGCCG ACAGTCAGCC 
ACGTTCAGCC TGTCAGTGCT GGACAGCAGC GAGCAACTGT CCACAACAAC TGCTATTCAT 
GAGGACAGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005166526.1
CDS	251..2182
Translation	MTSPAHSTATEASWTAGAADLQMTEALHLRNDGVRFPSSVPVDPAVITQHPPSHLHPRMSVYSATRPTLSRSFLQGRVYNFLERPTGWKCFVYHFTVFLIVLSCLILSVLSTIDEYQALANKTLFWMELVLVMFFGVEYVVRLWSAGCRSKYVGILGRLRFARKPISVIDLIVVVASIIVLAFGSNGQVFATSAVRGVRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVDDHGNSGFGSYADALWWGVVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQASWRCFALLNPDSATYKLFVKRNLSSSGSSPKLKVKMRRKMKISDRNNGQNSPAVPSITYDSFDDGRDSRQETLTSLQQSERAPSWNSLSSFQFSTPPATKPGVFEVSSRPTLQRSSSIADDMETEPEREIVLIPVAHVSQLRDSHRAAIRVIQRMYYFVARKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDHSLGKQSLFQTSSERLKDKGTNTIGSRLNRMDEKITHMDRTLNSIAESLNLMLARERRGDLARGKEQRSTMRRQSATFSLSVLDSSEQLSTTTAIHEDS

Target ORF information:

RefSeq Version	XM_005166469.3
Organism	Danio rerio(Zebrafish)
Definition	Danio rerio potassium voltage-gated channel, KQT-like subfamily, member 1 (kcnq1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005166469.3

ORF Insert Sequence:

ATGACCTCCC CAGCTCACAG TACAGCCACC GAGGCTTCAT GGACTGCTGG AGCCGCAGAC 
CTGCAGATGA CCGAGGCTCT GCACCTGCGG AATGACGGCG TGCGCTTCCC CTCCTCGGTG 
CCCGTGGATC CGGCGGTGAT CACGCAGCAC CCGCCGTCTC ACCTCCATCC CCGCATGTCC 
GTGTACAGCG CCACACGCCC CACACTCTCC AGGTCCTTCC TTCAAGGACG TGTTTATAAT 
TTCTTGGAGA GACCCACGGG TTGGAAATGC TTTGTGTATC ATTTTACAGT ATTCCTCATT 
GTGCTTTCCT GCCTGATCCT CAGTGTGCTG TCCACCATCG ACGAGTATCA AGCACTGGCT 
AATAAAACAC TATTCTGGAT GGAATTAGTG CTGGTAATGT TCTTTGGTGT GGAGTACGTG 
GTCCGTCTGT GGTCAGCTGG ATGCCGGAGT AAATATGTGG GAATTCTGGG CAGGCTTCGC 
TTTGCCCGAA AGCCAATTTC TGTTATTGAC CTGATTGTGG TGGTGGCTTC TATTATAGTA 
TTGGCATTTG GCTCTAATGG CCAGGTATTT GCTACCTCTG CTGTCAGAGG AGTCCGCTTC 
CTTCAAATTC TGCGAATGCT GCATGTGGAT CGACAAGGTG GAACATGGCG GTTGCTTGGA 
TCAGTAGTGT TTATACATCG ACAGGAACTG ATCACAACTC TCTATATCGG ATTCCTGGGG 
CTCATCTTCT CCTCCTACTT TGTGTATCTG GCAGAGAAGG ATGCGGTGGA TGACCACGGC 
AACTCTGGGT TTGGCAGCTA CGCCGATGCT CTGTGGTGGG GTGTGGTAAC AGTAACCACT 
ATTGGCTACG GAGACAAGGT TCCTCAGACT TGGATAGGAA AGACTATTGC ATCATGTTTC 
TCTGTCTTCG CTATCTCCTT TTTTGCCCTC CCTGCAGGAA TCCTGGGCTC CGGTTTTGCT 
CTGAAGGTAC AGCAGAAACA GAGACAAAAA CATTTCAACA GGCAAATTCC TGCAGCTGCG 
AGTCTCATAC AGGCGTCCTG GAGGTGTTTC GCCTTGCTGA ACCCTGATTC TGCCACATAC 
AAGTTATTTG TGAAACGAAA TCTCAGCAGT TCAGGGTCTA GCCCTAAATT AAAGGTGAAG 
ATGAGGAGGA AAATGAAGAT TAGTGACCGG AATAACGGGC AGAATTCTCC TGCAGTACCT 
TCCATAACCT ATGACTCCTT TGATGATGGG AGGGACAGCA GGCAAGAGAC ACTGACCAGT 
CTTCAACAGT CAGAACGAGC GCCGTCCTGG AACTCTCTGT CCTCGTTCCA GTTCTCCACA 
CCTCCAGCCA CGAAGCCTGG GGTTTTCGAG GTCTCATCTC GGCCCACGCT TCAGAGGAGC 
AGCAGCATTG CAGATGATAT GGAGACTGAG CCGGAGCGAG AGATTGTGCT CATTCCAGTC 
GCTCATGTGT CTCAGTTGCG GGATTCTCAT CGAGCAGCCA TCCGTGTGAT CCAGAGAATG 
TACTACTTTG TGGCCAGAAA GAAGTTTCAG CAAGCACGTA AGCCATATGA TGTGCGTGAC 
GTCATTGAGC AGTATTCACA GGGCCATCTC AACCTCATGG TGCGCATCAA GGAGCTGCAA 
AGAAGACTGG ATCACTCTTT AGGGAAGCAG TCCCTTTTCC AGACAAGTTC AGAGCGCTTG 
AAAGACAAAG GCACAAACAC TATTGGCTCC AGACTCAACA GAATGGATGA GAAGATCACA 
CACATGGACA GGACCCTCAA CAGCATTGCT GAGTCGCTCA ACCTCATGCT GGCGAGGGAG 
AGACGGGGGG ATCTGGCCAG GGGGAAGGAG CAGCGAAGCA CCATGCGCCG ACAGTCAGCC 
ACGTTCAGCC TGTCAGTGCT GGACAGCAGC GAGCAACTGT CCACAACAAC TGCTATTCAT 
GAGGACAGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Coordinated Expression of Two Types of Low-Threshold K
eNeuro4(5)(2017 Sep-Oct)
Watanabe T,Shimazaki T,Oda Y

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
BMC genomics17368(2016 05)
Pasquier J,Cabau C,Nguyen T,Jouanno E,Severac D,Braasch I,Journot L,Pontarotti P,Klopp C,Postlethwait JH,Guiguen Y,Bobe J

Assignment of Functional Relevance to Genes at Type 2 Diabetes-Associated Loci Through Investigation of ?-Cell Mass Deficits.
Molecular endocrinology (Baltimore, Md.)30(4)429-45(2016 Apr)
O'Hare EA,Yerges-Armstrong LM,Perry JA,Shuldiner AR,Zaghloul NA

Kcnq1-5 (Kv7.1-5) potassium channel expression in the adult zebrafish.
BMC physiology141(2014 Feb)
Wu C,Sharma K,Laster K,Hersi M,Torres C,Lukas TJ,Moore EJ

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KCNQ1 cDNA ORF clone, Danio rerio(Zebrafish)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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