bmpr2b cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	bmpr2b
Entrez Gene ID	555655
Full Name	bone morphogenetic protein receptor, type II b (serine/threonine kinase)
General protein information	Preferred Names bone morphogenetic protein receptor, type II b (serine/threonine kinase) Names bone morphogenetic protein receptor type-2 bone morphogenetic protein receptor type II b
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001039807.1	NP_001034896.1	bone morphogenetic protein receptor type-2 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	BMPR2	NP_001195.2
	BMPR2	XP_001101663.1
Danio rerio (zebrafish)	bmpr2b	NP_001034896.1
Pan troglodytes (chimpanzee)	BMPR2	XP_001172748.1
Mus musculus (house mouse)	Bmpr2	NP_031587.1
Bos taurus (cattle)	BMPR2	XP_002685538.2
Gallus gallus (chicken)	BMPR2	NP_001001465.1
Canis lupus familiaris (dog)	BMPR2	XP_536035.3
Rattus norvegicus (Norway rat)	Bmpr2	NP_536332.1
Xenopus tropicalis (tropical clawed frog)	bmpr2	XP_002937761.2

Gene Ontology
Bibliography

Related articles in PubMed

Evolution of complexity in the zebrafish synapse proteome.
Bay?s ?, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG
Nature communications814613(2017 Mar)

Down-regulation of coasy, the gene associated with NBIA-VI, reduces Bmp signaling, perturbs dorso-ventral patterning and alters neuronal development in zebrafish.
Khatri D, Zizioli D, Tiso N, Facchinello N, Vezzoli S, Gianoncelli A, Memo M, Monti E, Borsani G, Finazzi D
Scientific reports637660(2016 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

bmpr2b mediates BMP signaling and is required to establish left-right asymmetry.
Title: Two novel type II receptors mediate BMP signalling and are required to establish left-right asymmetry in zebrafish.

The following bmpr2b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the bmpr2b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa01557	NM_001039807.1 Latest version!	Danio rerio bone morphogenetic protein receptor, type II b (serine/threonine kinase) (bmpr2b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$629.30 $899.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

bmpr2b ( NM_001039807.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001034896.1 Danio rerio bone morphogenetic protein receptor, type II b (serine/threonine kinase) (bmpr2b), mRNA.

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CloneID	ODa01557
Clone ID Related Accession (Same CDS sequence)	NM_001039807.1
Accession Version	NM_001039807.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3216bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-15
Organism	Danio rerio(zebrafish)
Product	bone morphogenetic protein receptor type-2 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from DQ002899.1. On Mar 17, 2006 this sequence version replaced XM_678226.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DQ002899.1, BC163200.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168447, SAMEA4476742 [ECO:0000348] ##Evidence-Data-END##

ATGAGAGTGC GGATCCTAAA CCGGACATCA GTACTGTCAC TCGGGCTCTG CTCACTGCTT 
CTGCTCAGTG CTGTGGCCGC TGCTCAGAGT GAAGAGCGCG AGCGGGAGTG TGCTTTTAAT 
GACCAGCACC AGCAGGTGGA TGAGCAGAGT GTGGCAGGTG ACTGGCACAT CACCAGAGAA 
AATAACACCA TCCTGTGCAG CAAGAGCAGC CGCTGCTACG GCCTCTGGGA GAAAACACAT 
GACGGAGAGA TCCGCCTGGT CAAACAAGGC TGTTGGACTT ACATTGGTGA CCAGCAGGAC 
TGCCATGACG ACCGTTGCGT GGTTACCACA ACGCCATCGC AGATCCAGAA TGGCACCTAC 
AGATTCTGCT GCTGCAGCAC CAACATGTGC AACGTCAACT TCACAGAGAA CTGGGTGCCC 
AGTCCCACCA GCACTGCCAA CCGTGATCAG CCGCCTATAC ACAGAGATGA GGCCATCTTC 
ATCGCCCTGG CCTCCGTCTC CATTGTGGCC GTCCTTATTG TCGCGCTGTT CTTTGGCTAT 
CGTGTGATGA TGGGCGAGTG TAAACAGGGC CTGCACAATA TGGACATGAT AGAGGCTGCG 
CCATCTGAAC CTTCGCTGGA TTTAGACAGT TTAAAGCTCC TCGAACTGAT TGGCCGAGGC 
CGCTACGGTT CCGTCTACAA GGGGTCTCTT GACGAACGGC CGGTTGCAGT AAAAGTTTTT 
ACCTATGCCA ACCGGCAGAA CTTTGTGAAT GAGCGCTCCA TCTACCGAGT GCCTCTTCTG 
GAGCATGAAA ACATTGCTCG CTTTATCGTC GGCGATGAGC GGATGACCAC TGACGGACGC 
ATGGAGTACC TGCTGGTCAT GGAGTACTAC CCTCATGGCT CGCTGTGCCG CTATCTGAGT 
CTGCACACGC TGGACTGGGT GAGCTGCTGT CGTCTGGCTC ATTCACTGAC CAGAGGACTG 
GCCTATCTGC ACACTGAGCT CCTGAGAGGA GATATATACA AACCTGCCAT TTCGCACCGG 
GATCTAAACA GCCGGAATGT TCTAGTGAAG AACGATGGCA CCTGTGTGAT CAGCGACTTC 
GGTCTGTCCA TGAAGCTGAC TGGAAATCGT CTGGTACGGC CTGGAGAAGA GGAAAACGCC 
GCCATCAGTG AGGTGGGCAC GATCCGCTAC ATGGCGCCGG AGGTGCTGGA GGGAGCCGTG 
AACCTCAGGG GCTGCGAGTC TGCATTGAAA CAGGTGGACA TGTACGCCAT CGGCCTCATC 
TACTGGGAGA CCTTTATGAG GTGCACTGAC CTTTTTCCAG GAGAGACAGT GCCAGAATAC 
CAGATGGCTT TCCAGGCCGA GGCGGGAAAC CACCCGTCCT TTGAGGACAT GCAGGTGTTG 
GTGTCCAGAG AGAAACAGAG ACCCAAGTTC CCAGAAGCCT GGAAGGAGAA CAGCCTGGCT 
GTGCGCTCTC TAAAGGAGAC TATGGAGGAT TGCTGGGATC AGGATGCAGA GGCTCGTCTG 
ACAGCGCAGT GTGCAGAGGA GCGTATGGCA GAACTGCTGC TGATTTGGGA AAGGAACAAA 
CCTGTCAGTC CCACCATCAA TCCCATGAGC ACAGCGCTGC AGAACGAGAG GAATCTGACC 
CACAGCCGCA GGGCTCCCAA AATGGGCTCT TACCCAGATT ACTCTTCATC CTCTTACATC 
GAGGATCATG AGGGCATGGT GAAGAACCTC CCAGGCGACG TCTCCACGTC TGGCACTTCC 
TCTGTGGGTG GTGTGGGCGT GAGTGGCAGC AGTGGGGGCG TTGCAGCGAC CGGAGAGAAG 
AACAGAAACT CCATCAACTA TGAAAGACAG CAAGCTCAGG CGCAAGCTCG ACTGCCCAGT 
CCTGAAACCA GCGGCACAAG TTTGTCCACC ACAACCACCA CAACAGGCCT CACACCCAGT 
ACCATCATGA CCACCATCTC CGAATCGGGC CACTCGGAGG ACACAGGAGC CGGAGGAAGT 
GTACCAGTGT GCCTTCAACT CACAGAGGAA GATCTGGAGA CCACCAAACT GGACCCCAAA 
GAGGTGGACA AGAACCTGAA AGAAAGTTCT GATGAGAATC TGATGGAGCA CTCGCAGAAA 
CAGTTCAGCG CCCCTGATCC ACTCAGCTCG GGCAGCACCA GTCTTTTATA CCCACTGATT 
AAACTCGCAG CAGAAGTGAC TGGAGGATCT GGAAGTGGTG GACAAACTGA TTTCGGGGTG 
GGCAGCAGTG GAATGAGCGA CACTCCCACA GCCATGTTTC CTCTCCCCAA ACAGCAGAAT 
CTCCCCAAGA GGCCCACTAG CTTACCCCTC AACACCAAAA ATCCTGGTAG GGAGTCTTCG 
TCGTCTCGAT TGAAATTCGG GAAGCACAAG TCCAACCTGA AGCAGGTGGA GACAGGTGTA 
GCCAAGATGA ACACTGTGGT GGCCGTCGAG CCACACTTGG CCACCGTCAC CAACAATGGA 
CCCAGTGTGC GCAGTGGTGC TGGAGTGGTC GTAGTAAATG GATATGGAGT GGGCAATGGT 
GCCAGCTCCT CTGATGCGTT TGGAAACACG AACCCCGTCG GGCCACAGGG TGAAGGTGGC 
GCTCCTCTGC TGCAGAGCCA GCTGAGCGGA GAAGACAGCC GACTCAACAT CAACATCAAC 
TCCAGCCCTG ATGAACACGA GCCCCTGCTA AGAAGAGAGC AGCCGGCCGC ACGGGATCAC 
TCCGGTCGCA CCAACTCCAA CAACAACAAC AGCAACATTC ACACCACTGC CACATTTTGT 
GCGCTCACCG CTGCAGACGC CCAGATAGAG GCTTTAACCT GCCTGTCGGG GGCGCCAGAT 
GGAAGGGATA ATGGGGTTCC ATTGAGGCCA CCTAAACCCA GAAGACCAGA GCGGCCAAAC 
TCACTGGACC TGTCAGCCTC TTCCCAGGAT TCTTCTCTTT TAGGTGAGGC CGTGTCGCAG 
GAGGGAAAGG CCGGATCAGC TGAGAAGATT AAAAAACGTG TGAAGACTCC TTATTCGTTG 
AAAAGATGGC GTCCTTCCAC ATGGGTCGTC TCCACTGATA CACTAGATGG AGAGGTGAAC 
AACAACGGGC ACAGCCAGCA GACGACGATG GCAGTAAGTG GAGGTGGTCA CCCAAGCGCT 
GGCCAATCAA AGTCCAGCAT CGCCGTGTTT TTGGTCGGCG GAGGAACAGC AACAGCTACT 
CTGACCTCCG ATCCTCCAGA TATGACCTGC CTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001034896.1
CDS	790..4005
Translation	MRVRILNRTSVLSLGLCSLLLLSAVAAAQSEERERECAFNDQHQQVDEQSVAGDWHITRENNTILCSKSSRCYGLWEKTHDGEIRLVKQGCWTYIGDQQDCHDDRCVVTTTPSQIQNGTYRFCCCSTNMCNVNFTENWVPSPTSTANRDQPPIHRDEAIFIALASVSIVAVLIVALFFGYRVMMGECKQGLHNMDMIEAAPSEPSLDLDSLKLLELIGRGRYGSVYKGSLDERPVAVKVFTYANRQNFVNERSIYRVPLLEHENIARFIVGDERMTTDGRMEYLLVMEYYPHGSLCRYLSLHTLDWVSCCRLAHSLTRGLAYLHTELLRGDIYKPAISHRDLNSRNVLVKNDGTCVISDFGLSMKLTGNRLVRPGEEENAAISEVGTIRYMAPEVLEGAVNLRGCESALKQVDMYAIGLIYWETFMRCTDLFPGETVPEYQMAFQAEAGNHPSFEDMQVLVSREKQRPKFPEAWKENSLAVRSLKETMEDCWDQDAEARLTAQCAEERMAELLLIWERNKPVSPTINPMSTALQNERNLTHSRRAPKMGSYPDYSSSSYIEDHEGMVKNLPGDVSTSGTSSVGGVGVSGSSGGVAATGEKNRNSINYERQQAQAQARLPSPETSGTSLSTTTTTTGLTPSTIMTTISESGHSEDTGAGGSVPVCLQLTEEDLETTKLDPKEVDKNLKESSDENLMEHSQKQFSAPDPLSSGSTSLLYPLIKLAAEVTGGSGSGGQTDFGVGSSGMSDTPTAMFPLPKQQNLPKRPTSLPLNTKNPGRESSSSRLKFGKHKSNLKQVETGVAKMNTVVAVEPHLATVTNNGPSVRSGAGVVVVNGYGVGNGASSSDAFGNTNPVGPQGEGGAPLLQSQLSGEDSRLNININSSPDEHEPLLRREQPAARDHSGRTNSNNNNSNIHTTATFCALTAADAQIEALTCLSGAPDGRDNGVPLRPPKPRRPERPNSLDLSASSQDSSLLGEAVSQEGKAGSAEKIKKRVKTPYSLKRWRPSTWVVSTDTLDGEVNNNGHSQQTTMAVSGGGHPSAGQSKSSIAVFLVGGGTATATLTSDPPDMTCL

Target ORF information:

RefSeq Version	NM_001039807.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio bone morphogenetic protein receptor, type II b (serine/threonine kinase) (bmpr2b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001039807.1

ORF Insert Sequence:

ATGAGAGTGC GGATCCTAAA CCGGACATCA GTACTGTCAC TCGGGCTCTG CTCACTGCTT 
CTGCTCAGTG CTGTGGCCGC TGCTCAGAGT GAAGAGCGCG AGCGGGAGTG TGCTTTTAAT 
GACCAGCACC AGCAGGTGGA TGAGCAGAGT GTGGCAGGTG ACTGGCACAT CACCAGAGAA 
AATAACACCA TCCTGTGCAG CAAGAGCAGC CGCTGCTACG GCCTCTGGGA GAAAACACAT 
GACGGAGAGA TCCGCCTGGT CAAACAAGGC TGTTGGACTT ACATTGGTGA CCAGCAGGAC 
TGCCATGACG ACCGTTGCGT GGTTACCACA ACGCCATCGC AGATCCAGAA TGGCACCTAC 
AGATTCTGCT GCTGCAGCAC CAACATGTGC AACGTCAACT TCACAGAGAA CTGGGTGCCC 
AGTCCCACCA GCACTGCCAA CCGTGATCAG CCGCCTATAC ACAGAGATGA GGCCATCTTC 
ATCGCCCTGG CCTCCGTCTC CATTGTGGCC GTCCTTATTG TCGCGCTGTT CTTTGGCTAT 
CGTGTGATGA TGGGCGAGTG TAAACAGGGC CTGCACAATA TGGACATGAT AGAGGCTGCG 
CCATCTGAAC CTTCGCTGGA TTTAGACAGT TTAAAGCTCC TCGAACTGAT TGGCCGAGGC 
CGCTACGGTT CCGTCTACAA GGGGTCTCTT GACGAACGGC CGGTTGCAGT AAAAGTTTTT 
ACCTATGCCA ACCGGCAGAA CTTTGTGAAT GAGCGCTCCA TCTACCGAGT GCCTCTTCTG 
GAGCATGAAA ACATTGCTCG CTTTATCGTC GGCGATGAGC GGATGACCAC TGACGGACGC 
ATGGAGTACC TGCTGGTCAT GGAGTACTAC CCTCATGGCT CGCTGTGCCG CTATCTGAGT 
CTGCACACGC TGGACTGGGT GAGCTGCTGT CGTCTGGCTC ATTCACTGAC CAGAGGACTG 
GCCTATCTGC ACACTGAGCT CCTGAGAGGA GATATATACA AACCTGCCAT TTCGCACCGG 
GATCTAAACA GCCGGAATGT TCTAGTGAAG AACGATGGCA CCTGTGTGAT CAGCGACTTC 
GGTCTGTCCA TGAAGCTGAC TGGAAATCGT CTGGTACGGC CTGGAGAAGA GGAAAACGCC 
GCCATCAGTG AGGTGGGCAC GATCCGCTAC ATGGCGCCGG AGGTGCTGGA GGGAGCCGTG 
AACCTCAGGG GCTGCGAGTC TGCATTGAAA CAGGTGGACA TGTACGCCAT CGGCCTCATC 
TACTGGGAGA CCTTTATGAG GTGCACTGAC CTTTTTCCAG GAGAGACAGT GCCAGAATAC 
CAGATGGCTT TCCAGGCCGA GGCGGGAAAC CACCCGTCCT TTGAGGACAT GCAGGTGTTG 
GTGTCCAGAG AGAAACAGAG ACCCAAGTTC CCAGAAGCCT GGAAGGAGAA CAGCCTGGCT 
GTGCGCTCTC TAAAGGAGAC TATGGAGGAT TGCTGGGATC AGGATGCAGA GGCTCGTCTG 
ACAGCGCAGT GTGCAGAGGA GCGTATGGCA GAACTGCTGC TGATTTGGGA AAGGAACAAA 
CCTGTCAGTC CCACCATCAA TCCCATGAGC ACAGCGCTGC AGAACGAGAG GAATCTGACC 
CACAGCCGCA GGGCTCCCAA AATGGGCTCT TACCCAGATT ACTCTTCATC CTCTTACATC 
GAGGATCATG AGGGCATGGT GAAGAACCTC CCAGGCGACG TCTCCACGTC TGGCACTTCC 
TCTGTGGGTG GTGTGGGCGT GAGTGGCAGC AGTGGGGGCG TTGCAGCGAC CGGAGAGAAG 
AACAGAAACT CCATCAACTA TGAAAGACAG CAAGCTCAGG CGCAAGCTCG ACTGCCCAGT 
CCTGAAACCA GCGGCACAAG TTTGTCCACC ACAACCACCA CAACAGGCCT CACACCCAGT 
ACCATCATGA CCACCATCTC CGAATCGGGC CACTCGGAGG ACACAGGAGC CGGAGGAAGT 
GTACCAGTGT GCCTTCAACT CACAGAGGAA GATCTGGAGA CCACCAAACT GGACCCCAAA 
GAGGTGGACA AGAACCTGAA AGAAAGTTCT GATGAGAATC TGATGGAGCA CTCGCAGAAA 
CAGTTCAGCG CCCCTGATCC ACTCAGCTCG GGCAGCACCA GTCTTTTATA CCCACTGATT 
AAACTCGCAG CAGAAGTGAC TGGAGGATCT GGAAGTGGTG GACAAACTGA TTTCGGGGTG 
GGCAGCAGTG GAATGAGCGA CACTCCCACA GCCATGTTTC CTCTCCCCAA ACAGCAGAAT 
CTCCCCAAGA GGCCCACTAG CTTACCCCTC AACACCAAAA ATCCTGGTAG GGAGTCTTCG 
TCGTCTCGAT TGAAATTCGG GAAGCACAAG TCCAACCTGA AGCAGGTGGA GACAGGTGTA 
GCCAAGATGA ACACTGTGGT GGCCGTCGAG CCACACTTGG CCACCGTCAC CAACAATGGA 
CCCAGTGTGC GCAGTGGTGC TGGAGTGGTC GTAGTAAATG GATATGGAGT GGGCAATGGT 
GCCAGCTCCT CTGATGCGTT TGGAAACACG AACCCCGTCG GGCCACAGGG TGAAGGTGGC 
GCTCCTCTGC TGCAGAGCCA GCTGAGCGGA GAAGACAGCC GACTCAACAT CAACATCAAC 
TCCAGCCCTG ATGAACACGA GCCCCTGCTA AGAAGAGAGC AGCCGGCCGC ACGGGATCAC 
TCCGGTCGCA CCAACTCCAA CAACAACAAC AGCAACATTC ACACCACTGC CACATTTTGT 
GCGCTCACCG CTGCAGACGC CCAGATAGAG GCTTTAACCT GCCTGTCGGG GGCGCCAGAT 
GGAAGGGATA ATGGGGTTCC ATTGAGGCCA CCTAAACCCA GAAGACCAGA GCGGCCAAAC 
TCACTGGACC TGTCAGCCTC TTCCCAGGAT TCTTCTCTTT TAGGTGAGGC CGTGTCGCAG 
GAGGGAAAGG CCGGATCAGC TGAGAAGATT AAAAAACGTG TGAAGACTCC TTATTCGTTG 
AAAAGATGGC GTCCTTCCAC ATGGGTCGTC TCCACTGATA CACTAGATGG AGAGGTGAAC 
AACAACGGGC ACAGCCAGCA GACGACGATG GCAGTAAGTG GAGGTGGTCA CCCAAGCGCT 
GGCCAATCAA AGTCCAGCAT CGCCGTGTTT TTGGTCGGCG GAGGAACAGC AACAGCTACT 
CTGACCTCCG ATCCTCCAGA TATGACCTGC CTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Evolution of complexity in the zebrafish synapse proteome.
Nature communications814613(2017 Mar)
Bay?s ?,Collins MO,Reig-Viader R,Gou G,Goulding D,Izquierdo A,Choudhary JS,Emes RD,Grant SG

Down-regulation of coasy, the gene associated with NBIA-VI, reduces Bmp signaling, perturbs dorso-ventral patterning and alters neuronal development in zebrafish.
Scientific reports637660(2016 Nov)
Khatri D,Zizioli D,Tiso N,Facchinello N,Vezzoli S,Gianoncelli A,Memo M,Monti E,Borsani G,Finazzi D

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bmpr2b cDNA ORF clone, Danio rerio(zebrafish)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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