lrrc23 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	lrrc23
Entrez Gene ID	450033
Full Name	leucine rich repeat containing 23
Synonyms	zgc:101782
General protein information	Preferred Names leucine rich repeat containing 23 Names leucine-rich repeat-containing protein 23
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001006054.1	NP_001006054.1	leucine-rich repeat-containing protein 23

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	LRRC23	XP_508974.1
Canis lupus familiaris (dog)	LRRC23	XP_005637272.1
Rattus norvegicus (Norway rat)	Lrrc23	NP_001013183.2
Mus musculus (house mouse)	Lrrc23	NP_038616.1
Gallus gallus (chicken)	LRRC23	XP_416514.2
Homo sapiens (human)	LRRC23	NP_001128689.1
Xenopus tropicalis (tropical clawed frog)	lrrc23	NP_001016525.1
	LRRC23	XP_001110883.1
Bos taurus (cattle)	LRRC23	NP_001033288.1
Rattus norvegicus (Norway rat)	LOC100911585	XP_006244691.1
Danio rerio (zebrafish)	lrrc23	NP_001006054.1

Gene Ontology
Bibliography

Related articles in PubMed

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y, Bobe J
BMC genomics17368(2016 05)

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

Zebrafish Ciliopathy Screen Plus Human Mutational Analysis Identifies C21orf59 and CCDC65 Defects as Causing Primary Ciliary Dyskinesia.
Austin-Tse C, Halbritter J, Zariwala MA, Gilberti RM, Gee HY, Hellman N, Pathak N, Liu Y, Panizzi JR, Patel-King RS, Tritschler D, Bower R, O'Toole E, Porath JD, Hurd TW, Chaki M, Diaz KA, Kohl S, Lovric S, Hwang DY, Braun DA, Schueler M, Airik R, Otto EA, Leigh MW, Noone PG, Carson JL, Davis SD, Pittman JE, Ferkol TW, Atkinson JJ, Olivier KN, Sagel SD, Dell SD, Rosenfeld M, Milla CE, Loges NT, Omran H, Porter ME, King SM, Knowles MR, Drummond IA, Hildebrandt F
American journal of human genetics93(4)672-86(2013 Oct)

RNA-sequencing analysis of TCDD-induced responses in zebrafish liver reveals high relatedness to in vivo mammalian models and conserved biological pathways.
Li ZH, Xu H, Zheng W, Lam SH, Gong Z
PloS one8(10)e77292(2013)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following lrrc23 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the lrrc23 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa01524	NM_001006054.1 Latest version!	Danio rerio leucine rich repeat containing 23 (lrrc23), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

lrrc23 ( NM_001006054.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001006054.1 Danio rerio leucine rich repeat containing 23 (lrrc23), mRNA.

Price & Availability↑

CloneID	ODa01524
Clone ID Related Accession (Same CDS sequence)	NM_001006054.1
Accession Version	NM_001006054.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 981bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Danio rerio(zebrafish)
Product	leucine-rich repeat-containing protein 23
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC083278.1. ##Evidence-Data-START## Transcript exon combination :: BC083278.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##

ATGTCAGACT CTGGTGAAGA TGAGGTATTG AAAGCAGACT CTGATCATGA GGGAGAGAAT 
GAGGATCTGG AAGAGAAAGA TAAATCAGAT GGAGATCAGC TAGAGTCTTG TCCACTAACC 
CAGGACATTT TAGCGAGAAG TTTATCTTTG CTATGTCGCA CAGGGAATGG TCTGTCTCAT 
GCCTATGTCA GACTTGATCT TAAAAATAAG GGTCTGACAG ACCTAGCCTT GCTCAGCTCC 
TTCATCCATC TGCGTTATTT GGACCTGTCC TCCAATCATT TGTCAGACTT CTCTCCACTG 
GCTGGTCTCA CTCAGCTGCT GTGGGTGAAG GGAGACAGCA ACCTGCTTCA GGGCTTTGAG 
GGACAGCCTT TCGGTCAGCT CACTTTCCTG CAGTGGCTCA GCATTGCAAG CAATCGGCTG 
TTTGATGTGA CGGGTCTCGG AGGCCCAGCA CTGGAAACCC TCAATCTTAC TGGTAATGGC 
ATCCAGACCA TGCAGGGCCT GGATCATCCA AATCTGACCA ATCTGGTGAC TCTGGAGCTC 
AGAGGAAATT GTTTGGAAAC AACAGATGGC ATTTACCTGC CCAACTTACG CCATTTGTAT 
CTGGCTCAGA ACAATATAAA GAAACTGGAG GGTCTGGAAA AGCTTGAGCG TCTCATCACT 
CTTCACCTCA GACATAACCA GTTAGAAACA CTGGATGGAC TCAGTGCCAG TATGAAATGC 
CTCGAGTATC TTAATGTCAG GGGGAACCTT ATATCTTCTA TGAGGGCTTT GCAGACTCTG 
GCAAGTGTAG GGCAAACACT AAAGGCACTT GTGCTTTTGG ACAACCCTAT TGCGAAGACT 
GACGATTACA GGCTTTATGT GATCTCACAA CTTCCTCACC TGGAGCGAGT GGACAAAGAT 
CCCGTCACAC CTGAAGAAAA ATTTGAGGCA CAAAAAAAGG AGTTTGAAGA TGACAATGCT 
GAAGATCAAG AGGACGACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001006054.1
CDS	283..1263
Translation	MSDSGEDEVLKADSDHEGENEDLEEKDKSDGDQLESCPLTQDILARSLSLLCRTGNGLSHAYVRLDLKNKGLTDLALLSSFIHLRYLDLSSNHLSDFSPLAGLTQLLWVKGDSNLLQGFEGQPFGQLTFLQWLSIASNRLFDVTGLGGPALETLNLTGNGIQTMQGLDHPNLTNLVTLELRGNCLETTDGIYLPNLRHLYLAQNNIKKLEGLEKLERLITLHLRHNQLETLDGLSASMKCLEYLNVRGNLISSMRALQTLASVGQTLKALVLLDNPIAKTDDYRLYVISQLPHLERVDKDPVTPEEKFEAQKKEFEDDNAEDQEDD

Target ORF information:

RefSeq Version	NM_001006054.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio leucine rich repeat containing 23 (lrrc23), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001006054.1

ORF Insert Sequence:

ATGTCAGACT CTGGTGAAGA TGAGGTATTG AAAGCAGACT CTGATCATGA GGGAGAGAAT 
GAGGATCTGG AAGAGAAAGA TAAATCAGAT GGAGATCAGC TAGAGTCTTG TCCACTAACC 
CAGGACATTT TAGCGAGAAG TTTATCTTTG CTATGTCGCA CAGGGAATGG TCTGTCTCAT 
GCCTATGTCA GACTTGATCT TAAAAATAAG GGTCTGACAG ACCTAGCCTT GCTCAGCTCC 
TTCATCCATC TGCGTTATTT GGACCTGTCC TCCAATCATT TGTCAGACTT CTCTCCACTG 
GCTGGTCTCA CTCAGCTGCT GTGGGTGAAG GGAGACAGCA ACCTGCTTCA GGGCTTTGAG 
GGACAGCCTT TCGGTCAGCT CACTTTCCTG CAGTGGCTCA GCATTGCAAG CAATCGGCTG 
TTTGATGTGA CGGGTCTCGG AGGCCCAGCA CTGGAAACCC TCAATCTTAC TGGTAATGGC 
ATCCAGACCA TGCAGGGCCT GGATCATCCA AATCTGACCA ATCTGGTGAC TCTGGAGCTC 
AGAGGAAATT GTTTGGAAAC AACAGATGGC ATTTACCTGC CCAACTTACG CCATTTGTAT 
CTGGCTCAGA ACAATATAAA GAAACTGGAG GGTCTGGAAA AGCTTGAGCG TCTCATCACT 
CTTCACCTCA GACATAACCA GTTAGAAACA CTGGATGGAC TCAGTGCCAG TATGAAATGC 
CTCGAGTATC TTAATGTCAG GGGGAACCTT ATATCTTCTA TGAGGGCTTT GCAGACTCTG 
GCAAGTGTAG GGCAAACACT AAAGGCACTT GTGCTTTTGG ACAACCCTAT TGCGAAGACT 
GACGATTACA GGCTTTATGT GATCTCACAA CTTCCTCACC TGGAGCGAGT GGACAAAGAT 
CCCGTCACAC CTGAAGAAAA ATTTGAGGCA CAAAAAAAGG AGTTTGAAGA TGACAATGCT 
GAAGATCAAG AGGACGACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
BMC genomics17368(2016 05)
Pasquier J,Cabau C,Nguyen T,Jouanno E,Severac D,Braasch I,Journot L,Pontarotti P,Klopp C,Postlethwait JH,Guiguen Y,Bobe J

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

Zebrafish Ciliopathy Screen Plus Human Mutational Analysis Identifies C21orf59 and CCDC65 Defects as Causing Primary Ciliary Dyskinesia.
American journal of human genetics93(4)672-86(2013 Oct)
Austin-Tse C,Halbritter J,Zariwala MA,Gilberti RM,Gee HY,Hellman N,Pathak N,Liu Y,Panizzi JR,Patel-King RS,Tritschler D,Bower R,O'Toole E,Porath JD,Hurd TW,Chaki M,Diaz KA,Kohl S,Lovric S,Hwang DY,Braun DA,Schueler M,Airik R,Otto EA,Leigh MW,Noone PG,Carson JL,Davis SD,Pittman JE,Ferkol TW,Atkinson JJ,Olivier KN,Sagel SD,Dell SD,Rosenfeld M,Milla CE,Loges NT,Omran H,Porter ME,King SM,Knowles MR,Drummond IA,Hildebrandt F

RNA-sequencing analysis of TCDD-induced responses in zebrafish liver reveals high relatedness to in vivo mammalian models and conserved biological pathways.
PloS one8(10)e77292(2013)
Li ZH,Xu H,Zheng W,Lam SH,Gong Z