tmbim1a cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	tmbim1a
Entrez Gene ID	449819
Full Name	transmembrane BAX inhibitor motif containing 1a
Synonyms	tmbim1,zgc:103528
General protein information	Preferred Names transmembrane BAX inhibitor motif containing 1a Names protein lifeguard 3 transmembrane BAX inhibitor motif containing 1
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001005992.2	NP_001005992.2	protein lifeguard 3

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	TMBIM1	XP_005640784.1
Bos taurus (cattle)	TMBIM1	NP_991367.1
Pan troglodytes (chimpanzee)	TMBIM1	XP_001144519.2
	TMBIM1	XP_001089836.1
Rattus norvegicus (Norway rat)	Tmbim1	NP_001007714.1
Danio rerio (zebrafish)	tmbim1	NP_001005992.1
Xenopus tropicalis (tropical clawed frog)	tmbim1	NP_001025668.1
Homo sapiens (human)	TMBIM1	NP_071435.2
Gallus gallus (chicken)	TMBIM1	XP_422067.3
Mus musculus (house mouse)	Tmbim1	NP_081430.3

Gene Ontology
Bibliography

Related articles in PubMed

Function-driven discovery of disease genes in zebrafish using an integrated genomics big data resource.
Shim H, Kim JH, Kim CY, Hwang S, Kim H, Yang S, Lee JE, Lee I
Nucleic acids research44(20)9611-9623(2016 Nov)

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

Many genes in fish have species-specific asymmetric rates of molecular evolution.
Steinke D, Salzburger W, Braasch I, Meyer A
BMC genomics720(2006 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following tmbim1a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the tmbim1a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa41293	NM_001005992.2 Latest version!	Danio rerio transmembrane BAX inhibitor motif containing 1a (tmbim1a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$174.30 $249.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

tmbim1a ( NM_001005992.2 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001005992.2 Danio rerio transmembrane BAX inhibitor motif containing 1a (tmbim1a), mRNA.

Price & Availability↑

CloneID	ODa41293
Clone ID Related Accession (Same CDS sequence)	NM_001005992.2
Accession Version	NM_001005992.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 999bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-11-23
Organism	Danio rerio(zebrafish)
Product	protein lifeguard 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CU639421.4. On Aug 22, 2015 this sequence version replaced NM_001005992.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BC083414.1, GFIL01040901.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2168446, SAMEA2168447 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCTAGAT CAGATTTCCC TCCTTCTTAT GATGATTCTC GACTGCTGTC AAACACTCAG 
CCGGGGCCAG GTTATCCTCC TTCTGCTCCT CCATATGGAT TTAGTCCATA TGAGGGACAA 
CCGGGATACC CACAGCCTAA TGATCCATAC CGAGGACAGC CCAATGATCC ATACCGAGGA 
CAGCCTAATG ATCCATACCG AGGACAGCCT AATGATCCAT ACCGAGGACA GCCGGCCGGA 
TACCCCCCTC CAGCTATGCC AGTCATCCCC GTCATGCCTC CTCCTGGGAT AGGTGACAGT 
GAAGGATTTA CCACAGCTGA AGGATTCGAG AGCACTGATG TCCGGCACAG TTTTATACGC 
AAAGTTTATC TGATCCTCGC TGCTCAGCTT CTTGTCACTG CTGCCGTCGT GGCTATTTTC 
ACATTTGTGG AACCAGTAGG ATTGTTTGTG AGGAAGAACC CCGCCATCTA CTGGGTTTCA 
TATGCCATCT ATTTTGTCAC ACATATAGTA CTGGTTTGCT GTCAGGGACC CAGGAGGCGT 
TTTCCATGGA ACCTGCTCCT GTTGGCCATT TTTACACTGG CCTTATCTTT CATGACTGGA 
AATATAGCAA GTTATTACAG CACTAGAGCG GTGTTCCTGG CCCTGGCCAT CACAGTTGTC 
GTGTGTGTAG CAGTGACTGT GTTCTGCTTT CAGACGAAGG TGGACTTCAC CAAATGTTCT 
GGCTTTTTCT GTGTACTCGG AATCGTAGTG TTTGTGACCG GCATCATCAC TGCTATTGTC 
CTGTCATTTA AATATGTCCC ATGGCTACAC ATGCTTTATG CATCTATAGG AGCCATTGCA 
TTCACTTTGT TTCTGGCCTA TCACACTCAG CTGCTCATCG GGAACCGGAA GCTCTCCATC 
AGCCCAGAAG AGTATGTGTT CGCTGCTCTC TCCCTTTATG TTGACATTGT GCAGATCTTC 
ATCTTCCTCC TGCAAATCAT CGGTTACGCA GAGAGATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001005992.2
CDS	217..1215
Translation	MSRSDFPPSYDDSRLLSNTQPGPGYPPSAPPYGFSPYEGQPGYPQPNDPYRGQPNDPYRGQPNDPYRGQPNDPYRGQPAGYPPPAMPVIPVMPPPGIGDSEGFTTAEGFESTDVRHSFIRKVYLILAAQLLVTAAVVAIFTFVEPVGLFVRKNPAIYWVSYAIYFVTHIVLVCCQGPRRRFPWNLLLLAIFTLALSFMTGNIASYYSTRAVFLALAITVVVCVAVTVFCFQTKVDFTKCSGFFCVLGIVVFVTGIITAIVLSFKYVPWLHMLYASIGAIAFTLFLAYHTQLLIGNRKLSISPEEYVFAALSLYVDIVQIFIFLLQIIGYAER

Target ORF information:

RefSeq Version	NM_001005992.2
Organism	Danio rerio(zebrafish)
Definition	Danio rerio transmembrane BAX inhibitor motif containing 1a (tmbim1a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001005992.2

ORF Insert Sequence:

ATGTCTAGAT CAGATTTCCC TCCTTCTTAT GATGATTCTC GACTGCTGTC AAACACTCAG 
CCGGGGCCAG GTTATCCTCC TTCTGCTCCT CCATATGGAT TTAGTCCATA TGAGGGACAA 
CCGGGATACC CACAGCCTAA TGATCCATAC CGAGGACAGC CCAATGATCC ATACCGAGGA 
CAGCCTAATG ATCCATACCG AGGACAGCCT AATGATCCAT ACCGAGGACA GCCGGCCGGA 
TACCCCCCTC CAGCTATGCC AGTCATCCCC GTCATGCCTC CTCCTGGGAT AGGTGACAGT 
GAAGGATTTA CCACAGCTGA AGGATTCGAG AGCACTGATG TCCGGCACAG TTTTATACGC 
AAAGTTTATC TGATCCTCGC TGCTCAGCTT CTTGTCACTG CTGCCGTCGT GGCTATTTTC 
ACATTTGTGG AACCAGTAGG ATTGTTTGTG AGGAAGAACC CCGCCATCTA CTGGGTTTCA 
TATGCCATCT ATTTTGTCAC ACATATAGTA CTGGTTTGCT GTCAGGGACC CAGGAGGCGT 
TTTCCATGGA ACCTGCTCCT GTTGGCCATT TTTACACTGG CCTTATCTTT CATGACTGGA 
AATATAGCAA GTTATTACAG CACTAGAGCG GTGTTCCTGG CCCTGGCCAT CACAGTTGTC 
GTGTGTGTAG CAGTGACTGT GTTCTGCTTT CAGACGAAGG TGGACTTCAC CAAATGTTCT 
GGCTTTTTCT GTGTACTCGG AATCGTAGTG TTTGTGACCG GCATCATCAC TGCTATTGTC 
CTGTCATTTA AATATGTCCC ATGGCTACAC ATGCTTTATG CATCTATAGG AGCCATTGCA 
TTCACTTTGT TTCTGGCCTA TCACACTCAG CTGCTCATCG GGAACCGGAA GCTCTCCATC 
AGCCCAGAAG AGTATGTGTT CGCTGCTCTC TCCCTTTATG TTGACATTGT GCAGATCTTC 
ATCTTCCTCC TGCAAATCAT CGGTTACGCA GAGAGATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Function-driven discovery of disease genes in zebrafish using an integrated genomics big data resource.
Nucleic acids research44(20)9611-9623(2016 Nov)
Shim H,Kim JH,Kim CY,Hwang S,Kim H,Yang S,Lee JE,Lee I

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

Many genes in fish have species-specific asymmetric rates of molecular evolution.
BMC genomics720(2006 Feb)
Steinke D,Salzburger W,Braasch I,Meyer A

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tmbim1a cDNA ORF clone, Danio rerio(zebrafish)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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