cav2 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	cav2
Entrez Gene ID	415240
Full Name	caveolin 2
Synonyms	wu:fc52e01,zgc:86696
General protein information	Preferred Names caveolin 2 Names caveolin-2
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001002150.1	NP_001002150.1	caveolin-2

Pathways from BioSystems

Homologies

Bos taurus (cattle)	CAV2	NP_001007809.1
Rattus norvegicus (Norway rat)	Cav2	NP_571989.2
Gallus gallus (chicken)	CAV2	NP_001007087.1
Xenopus tropicalis (tropical clawed frog)	cav2	NP_001015763.1
Homo sapiens (human)	CAV2	NP_001224.1
	CAV2	NP_001162090.1
Mus musculus (house mouse)	Cav2	NP_058596.1
Danio rerio (zebrafish)	cav2	NP_001002150.1
Canis lupus familiaris (dog)	CAV2	NP_001010997.2
Pan troglodytes (chimpanzee)	CAV2	NP_001129298.1

Gene Ontology
Bibliography

Related articles in PubMed

Caveolae Protect Notochord Cells against Catastrophic Mechanical Failure during Development.
Lim YW, Lo HP, Ferguson C, Martel N, Giacomotto J, Gomez GA, Yap AS, Hall TE, Parton RG
Current biology : CB27(13)1968-1981.e7(2017 Jul)

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y, Bobe J
BMC genomics17368(2016 05)

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

The zebrafish gene map defines ancestral vertebrate chromosomes.
Woods IG, Wilson C, Friedlander B, Chang P, Reyes DK, Nix R, Kelly PD, Chu F, Postlethwait JH, Talbot WS
Genome research15(9)1307-14(2005 Sep)

Zebrafish as a model for caveolin-associated muscle disease; caveolin-3 is required for myofibril organization and muscle cell patterning.
Nixon SJ, Wegner J, Ferguson C, M?ry PF, Hancock JF, Currie PD, Key B, Westerfield M, Parton RG
Human molecular genetics14(13)1727-43(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following cav2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the cav2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa33191	NM_001002150.1 Latest version!	Danio rerio caveolin 2 (cav2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

cav2 ( NM_001002150.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001002150.1 Danio rerio caveolin 2 (cav2), mRNA.

Price & Availability↑

CloneID	ODa33191
Clone ID Related Accession (Same CDS sequence)	NM_001002150.1
Accession Version	NM_001002150.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 489bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-03-07
Organism	Danio rerio(zebrafish)
Product	caveolin-2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC071376.1. ##Evidence-Data-START## Transcript exon combination :: BC071376.1, EH590261.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##

ATGGGTCTAG AAAAAGAAAA ATCAGAGACC AGGGTGATAA TGGATGAGGA TGAGTTCAAC 
AGATCGATTG AACCTATACT TGGAAAGAAA CCGAACGTGT ATTCGGAGGT TCAGGACAGA 
GATCCTAAAG ATATCAACAA GCACCTAAAG GTTGGTTTTG AAGACATCAT CGCTGAGCCC 
AACTCCACAC ACAGCTTTGA CAGAGTTTGG ATTGGTAGTC ATGCTGTTTT CGAGTTGGTG 
AAATACGTCT TCTACCGGAT CCTCACCACG CTTCTGGCCA TTCCCATGGC GTTTATTGCA 
GGGATTGTTT TCGGGATCCT CAGCTGTATA CATATTTGGG TGGTGATGCC AGTGATCCAG 
GGCTGCATGA TGACACTGCC CTCCATCCAC GTGATCTGGA CCAGCTTGAT GGACATGTTT 
ATAGGGCCTT TCTTCTTCAG CATTGGACGG TGCTTGTCCT CCATCAACAT CAAGACTGAG 
CAAATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001002150.1
CDS	66..554
Translation	MGLEKEKSETRVIMDEDEFNRSIEPILGKKPNVYSEVQDRDPKDINKHLKVGFEDIIAEPNSTHSFDRVWIGSHAVFELVKYVFYRILTTLLAIPMAFIAGIVFGILSCIHIWVVMPVIQGCMMTLPSIHVIWTSLMDMFIGPFFFSIGRCLSSINIKTEQI

Target ORF information:

RefSeq Version	NM_001002150.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio caveolin 2 (cav2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001002150.1

ORF Insert Sequence:

ATGGGTCTAG AAAAAGAAAA ATCAGAGACC AGGGTGATAA TGGATGAGGA TGAGTTCAAC 
AGATCGATTG AACCTATACT TGGAAAGAAA CCGAACGTGT ATTCGGAGGT TCAGGACAGA 
GATCCTAAAG ATATCAACAA GCACCTAAAG GTTGGTTTTG AAGACATCAT CGCTGAGCCC 
AACTCCACAC ACAGCTTTGA CAGAGTTTGG ATTGGTAGTC ATGCTGTTTT CGAGTTGGTG 
AAATACGTCT TCTACCGGAT CCTCACCACG CTTCTGGCCA TTCCCATGGC GTTTATTGCA 
GGGATTGTTT TCGGGATCCT CAGCTGTATA CATATTTGGG TGGTGATGCC AGTGATCCAG 
GGCTGCATGA TGACACTGCC CTCCATCCAC GTGATCTGGA CCAGCTTGAT GGACATGTTT 
ATAGGGCCTT TCTTCTTCAG CATTGGACGG TGCTTGTCCT CCATCAACAT CAAGACTGAG 
CAAATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Caveolae Protect Notochord Cells against Catastrophic Mechanical Failure during Development.
Current biology : CB27(13)1968-1981.e7(2017 Jul)
Lim YW,Lo HP,Ferguson C,Martel N,Giacomotto J,Gomez GA,Yap AS,Hall TE,Parton RG

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
BMC genomics17368(2016 05)
Pasquier J,Cabau C,Nguyen T,Jouanno E,Severac D,Braasch I,Journot L,Pontarotti P,Klopp C,Postlethwait JH,Guiguen Y,Bobe J

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

The zebrafish gene map defines ancestral vertebrate chromosomes.
Genome research15(9)1307-14(2005 Sep)
Woods IG,Wilson C,Friedlander B,Chang P,Reyes DK,Nix R,Kelly PD,Chu F,Postlethwait JH,Talbot WS

Zebrafish as a model for caveolin-associated muscle disease; caveolin-3 is required for myofibril organization and muscle cell patterning.
Human molecular genetics14(13)1727-43(2005 Jul)
Nixon SJ,Wegner J,Ferguson C,M?ry PF,Hancock JF,Currie PD,Key B,Westerfield M,Parton RG