selenom cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	selenom
Entrez Gene ID	352913
Full Name	selenoprotein M
Synonyms	cb693,selm,sepm,wu:fc13f12,zgc:103431
General protein information	Preferred Names selenoprotein M Names selenoprotein M fc13f12
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)
Summary	The protein encoded by this gene belongs to the selenoprotein M/SEP15 family. The exact function of this protein is not known, but it may have a role in maintaining redox homeostasis. It is localized in the perinuclear region, and is highly expressed in the brain in mammals. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs in vertebrates contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. [provided by RefSeq, Aug 2017].

mRNA and Protein(s)

mRNA	Protein	Name
NM_178286.4	NP_840071.2	selenoprotein M precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	SELM	NP_536355.1
Mus musculus (house mouse)	Selm	NP_444497.1
Pan troglodytes (chimpanzee)	SELM	NP_001140172.1
Xenopus tropicalis (tropical clawed frog)	selm	NP_001165078.1
	SELM	NP_001152871.1
Canis lupus familiaris (dog)	SELM	NP_001108486.1
Rattus norvegicus (Norway rat)	Selm	NP_001108485.1
Danio rerio (zebrafish)	selm	NP_840071.2
Gallus gallus (chicken)	SELM	NP_001264788.1
Bos taurus (cattle)	SELM	NP_001156643.1

Gene Ontology
Bibliography

Related articles in PubMed

Selenoprotein Gene Nomenclature.
Gladyshev VN, Arn?r ES, Berry MJ, Brigelius-Floh? R, Bruford EA, Burk RF, Carlson BA, Castellano S, Chavatte L, Conrad M, Copeland PR, Diamond AM, Driscoll DM, Ferreiro A, Floh? L, Green FR, Guig? R, Handy DE, Hatfield DL, Hesketh J, Hoffmann PR, Holmgren A, Hondal RJ, Howard MT, Huang K, Kim HY, Kim IY, K?hrle J, Krol A, Kryukov GV, Lee BJ, Lee BC, Lei XG, Liu Q, Lescure A, Lobanov AV, Loscalzo J, Maiorino M, Mariotti M, Sandeep Prabhu K, Rayman MP, Rozovsky S, Salinas G, Schmidt EE, Schomburg L, Schweizer U, Simonovi? M, Sunde RA, Tsuji PA, Tweedie S, Ursini F, Whanger PD, Zhang Y
The Journal of biological chemistry291(46)24036-24040(2016 Nov)

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y, Bobe J
BMC genomics17368(2016 05)

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

Selenium prevents downregulation of antioxidant selenoprotein genes by methylmercury.
Penglase S, Hamre K, Ellingsen S
Free radical biology & medicine7595-104(2014 Oct)

Composition and evolution of the vertebrate and mammalian selenoproteomes.
Mariotti M, Ridge PG, Zhang Y, Lobanov AV, Pringle TH, Guigo R, Hatfield DL, Gladyshev VN
PloS one7(3)e33066(2012)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following selenom gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the selenom cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa37992	NM_178286.4 Latest version!	Danio rerio selenoprotein M (selenom), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

selenom ( NM_178286.4 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_840071.2 Danio rerio selenoprotein M (selenom), mRNA.

Price & Availability↑

CloneID	ODa37992
Clone ID Related Accession (Same CDS sequence)	NM_178286.4
Accession Version	NM_178286.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 456bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-25
Organism	Danio rerio(zebrafish)
Product	selenoprotein M precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from EH541157.1, EH538512.1 and EH559733.1. On Dec 16, 2016 this sequence version replaced NM_178286.3. ##Evidence-Data-START## Transcript exon combination :: GFIL01034750.1, EH562305.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## protein contains selenocysteine :: inferred from conservation ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGTGGCCGC TGATCTTCAC CGCACTGCTG CCGTCCGTCA TCCTGACCTA TGAAGTGAAC 
ATCGAGAAAC TGAGTGGCCT GGCGAGGGCT CGAGTAGAGA CGTGTGGTGG ATGACAGCTG 
AACAGGATGA GGGAGGTCAA GGCCTTTGTG ACCCAGGACA TTCCTCTTTA CCATAACCTG 
GTGATGAAGC ACATTCCTGG GGCCGATCCT GAACTCGTCC TCCTCAACCA CTATTATGAA 
GAACTAGATA GGATCCCATT ATCTGAAATG ACTCGCGCTG AGATTAACAA ACTGTTGGCC 
GAGCTGGGCT TTTATAAAAA GGATCATCCT GAAGACCAAG TGCCCGAGGA GTTTCGCTTC 
TCTCCAGCAA AAGACAGTCC CTTTGAGGGC CGGCAATCCA GCACGGCGGC CCCCGAGACG 
ACGGAGCCTT CAGATTCCCA ACACACTGAC CTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_840071.2
CDS	81..536
Translation	MWPLIFTALLPSVILTYEVNIEKLSGLARARVETCGG*QLNRMREVKAFVTQDIPLYHNLVMKHIPGADPELVLLNHYYEELDRIPLSEMTRAEINKLLAELGFYKKDHPEDQVPEEFRFSPAKDSPFEGRQSSTAAPETTEPSDSQHTDL

Target ORF information:

RefSeq Version	NM_178286.4
Organism	Danio rerio(zebrafish)
Definition	Danio rerio selenoprotein M (selenom), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_178286.4

ORF Insert Sequence:

ATGTGGCCGC TGATCTTCAC CGCACTGCTG CCGTCCGTCA TCCTGACCTA TGAAGTGAAC 
ATCGAGAAAC TGAGTGGCCT GGCGAGGGCT CGAGTAGAGA CGTGTGGTGG ATGACAGCTG 
AACAGGATGA GGGAGGTCAA GGCCTTTGTG ACCCAGGACA TTCCTCTTTA CCATAACCTG 
GTGATGAAGC ACATTCCTGG GGCCGATCCT GAACTCGTCC TCCTCAACCA CTATTATGAA 
GAACTAGATA GGATCCCATT ATCTGAAATG ACTCGCGCTG AGATTAACAA ACTGTTGGCC 
GAGCTGGGCT TTTATAAAAA GGATCATCCT GAAGACCAAG TGCCCGAGGA GTTTCGCTTC 
TCTCCAGCAA AAGACAGTCC CTTTGAGGGC CGGCAATCCA GCACGGCGGC CCCCGAGACG 
ACGGAGCCTT CAGATTCCCA ACACACTGAC CTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Selenoprotein Gene Nomenclature.
The Journal of biological chemistry291(46)24036-24040(2016 Nov)
Gladyshev VN,Arn?r ES,Berry MJ,Brigelius-Floh? R,Bruford EA,Burk RF,Carlson BA,Castellano S,Chavatte L,Conrad M,Copeland PR,Diamond AM,Driscoll DM,Ferreiro A,Floh? L,Green FR,Guig? R,Handy DE,Hatfield DL,Hesketh J,Hoffmann PR,Holmgren A,Hondal RJ,Howard MT,Huang K,Kim HY,Kim IY,K?hrle J,Krol A,Kryukov GV,Lee BJ,Lee BC,Lei XG,Liu Q,Lescure A,Lobanov AV,Loscalzo J,Maiorino M,Mariotti M,Sandeep Prabhu K,Rayman MP,Rozovsky S,Salinas G,Schmidt EE,Schomburg L,Schweizer U,Simonovi? M,Sunde RA,Tsuji PA,Tweedie S,Ursini F,Whanger PD,Zhang Y

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
BMC genomics17368(2016 05)
Pasquier J,Cabau C,Nguyen T,Jouanno E,Severac D,Braasch I,Journot L,Pontarotti P,Klopp C,Postlethwait JH,Guiguen Y,Bobe J

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

Selenium prevents downregulation of antioxidant selenoprotein genes by methylmercury.
Free radical biology & medicine7595-104(2014 Oct)
Penglase S,Hamre K,Ellingsen S

Composition and evolution of the vertebrate and mammalian selenoproteomes.
PloS one7(3)e33066(2012)
Mariotti M,Ridge PG,Zhang Y,Lobanov AV,Pringle TH,Guigo R,Hatfield DL,Gladyshev VN

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

selenom cDNA ORF clone, Danio rerio(zebrafish)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報