tollip cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	tollip
Entrez Gene ID	336876
Full Name	toll interacting protein
Synonyms	fk22a02,im:7145391,wu:fk22a02,zgc:76985
General protein information	Preferred Names toll interacting protein Names toll-interacting protein
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_207061.2	NP_996944.2	toll-interacting protein isoform 1
NM_001328590.1	NP_001315519.1	toll-interacting protein isoform 2

Pathways from BioSystems

Homologies

Bos taurus (cattle)	TOLLIP	NP_001035050.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP003615	XP_562476.3
	TOLLIP	XP_001090075.1
Mus musculus (house mouse)	Tollip	NP_076253.1
Gallus gallus (chicken)	TOLLIP	NP_001006471.1
Canis lupus familiaris (dog)	TOLLIP	XP_540778.2
Rattus norvegicus (Norway rat)	Tollip	NP_001103138.1
Pan troglodytes (chimpanzee)	TOLLIP	XP_508213.4
Danio rerio (zebrafish)	tollip	NP_996944.1
Xenopus tropicalis (tropical clawed frog)	tollip	NP_001006923.1
Homo sapiens (human)	TOLLIP	NP_061882.2
Caenorhabditis elegans (roundworm)	tli-1	NP_492757.2

Gene Ontology
Bibliography

Related articles in PubMed

Evolution of complexity in the zebrafish synapse proteome.
Bay?s ?, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG
Nature communications814613(2017 Mar)

Characterization and expression analysis of Toll-interacting protein in common carp, Cyprinus carpio L., responding to bacterial and viral challenge.
Shan S, Wang L, Zhang F, Zhu Y, An L, Yang G
SpringerPlus5639(2016)

Endocytic Adaptor Protein Tollip Inhibits Canonical Wnt Signaling.
Toru? A, Szyma?ska E, Castanon I, Woli?ska-Nizio? L, Bartosik A, Jastrz?bski K, Mi?tkowska M, Gonz?lez-Gait?n M, Miaczynska M
PloS one10(6)e0130818(2015)

Conservation and divergence of gene families encoding components of innate immune response systems in zebrafish.
Stein C, Caccamo M, Laird G, Leptin M
Genome biology8(11)R251(2007)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following tollip gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the tollip cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa40096	NM_001328590.1 Latest version!	Danio rerio toll interacting protein (tollip), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00
ODa98357	NM_207061.2 Latest version!	Danio rerio toll interacting protein (tollip), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$174.30 $249.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

tollip ( NM_001328590.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001315519.1 Danio rerio toll interacting protein (tollip), transcript variant 2, mRNA.

Price & Availability↑

CloneID	ODa40096
Clone ID Related Accession (Same CDS sequence)	NM_001328590.1
Accession Version	NM_001328590.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 759bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-01-26
Organism	Danio rerio(zebrafish)
Product	toll-interacting protein isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CU463038.10, EH451009.1, EH573127.1 and EH562339.1. On Jun 18, 2016 this sequence version replaced XM_009303653.1. ##Evidence-Data-START## Transcript exon combination :: EH451009.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##

ATGCCGACTC AGCAGCAGCA GCAAGTGCAG TTAGACGCAC AGGCGGCCCG ACAGCTGCAG 
TACGGAGGAT CTTTAGGCAC TGCTGGACGC CTCAGCATCA CTGTAGTACA GGCTAAGCTT 
GCAAAGAACT ATGGTATGAC ACGGATGGAC CCTTACTGCA GGATTCGACT GGGCTACGCT 
GTCTACGAGA CTCCAACCGC TCACAATGGA GCAAAAAACC CTCGCTGGAA CAAAGTCATC 
CAGTGCACCG TCCCTCCCGG GGTGGACTCC TTCTATCTGG AGATATTCGA TGAGAGGGCG 
TTTTCTATGG ATGATCGCAT CGCATGGACA CACGTCACAA TCCCTGAAAA CCTGCGGGAG 
GGAACTGTAG TGGACGAGTG GTACAGCCTG AGCGGGAGAC AGGGGGACGA CAAAGAGGGC 
ATGATTAATC TCGTCATGTC CTTTGCAACA ATACCCGCAG GAATGATGAT GCAGCCGCAG 
CCTGTGGTTC TGATGCCTAC AGTCTATCAG CAGGGAGTCG GTTATGTGCC CATAGCAGGC 
GTCCCTGGGA TGTATAATCA GGGTGTGGTG CCCATGGGGA TGCCAGCCGC TCCTCCAGTG 
GCGTCTCAGA GTGCCCCATG CAGCGAAGAA GACCTGAAAG CCCTTCAGGA CATGTTCCCC 
AACCTGGACA AAGAGGTGAT CCGCACGGTT TTAGAGGCGC AGCAGGGAAA TAAAGATGCT 
GCCATAAACT CCCTGCTGCA GATGGCGGAG GAGCTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001315519.1
CDS	158..916
Translation	MPTQQQQQVQLDAQAARQLQYGGSLGTAGRLSITVVQAKLAKNYGMTRMDPYCRIRLGYAVYETPTAHNGAKNPRWNKVIQCTVPPGVDSFYLEIFDERAFSMDDRIAWTHVTIPENLREGTVVDEWYSLSGRQGDDKEGMINLVMSFATIPAGMMMQPQPVVLMPTVYQQGVGYVPIAGVPGMYNQGVVPMGMPAAPPVASQSAPCSEEDLKALQDMFPNLDKEVIRTVLEAQQGNKDAAINSLLQMAEEL

Target ORF information:

RefSeq Version	NM_001328590.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio toll interacting protein (tollip), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001328590.1

ORF Insert Sequence:

ATGCCGACTC AGCAGCAGCA GCAAGTGCAG TTAGACGCAC AGGCGGCCCG ACAGCTGCAG 
TACGGAGGAT CTTTAGGCAC TGCTGGACGC CTCAGCATCA CTGTAGTACA GGCTAAGCTT 
GCAAAGAACT ATGGTATGAC ACGGATGGAC CCTTACTGCA GGATTCGACT GGGCTACGCT 
GTCTACGAGA CTCCAACCGC TCACAATGGA GCAAAAAACC CTCGCTGGAA CAAAGTCATC 
CAGTGCACCG TCCCTCCCGG GGTGGACTCC TTCTATCTGG AGATATTCGA TGAGAGGGCG 
TTTTCTATGG ATGATCGCAT CGCATGGACA CACGTCACAA TCCCTGAAAA CCTGCGGGAG 
GGAACTGTAG TGGACGAGTG GTACAGCCTG AGCGGGAGAC AGGGGGACGA CAAAGAGGGC 
ATGATTAATC TCGTCATGTC CTTTGCAACA ATACCCGCAG GAATGATGAT GCAGCCGCAG 
CCTGTGGTTC TGATGCCTAC AGTCTATCAG CAGGGAGTCG GTTATGTGCC CATAGCAGGC 
GTCCCTGGGA TGTATAATCA GGGTGTGGTG CCCATGGGGA TGCCAGCCGC TCCTCCAGTG 
GCGTCTCAGA GTGCCCCATG CAGCGAAGAA GACCTGAAAG CCCTTCAGGA CATGTTCCCC 
AACCTGGACA AAGAGGTGAT CCGCACGGTT TTAGAGGCGC AGCAGGGAAA TAAAGATGCT 
GCCATAAACT CCCTGCTGCA GATGGCGGAG GAGCTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

tollip ( NM_207061.2 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_996944.2 Danio rerio toll interacting protein (tollip), transcript variant 1, mRNA.

Price & Availability↑

CloneID	ODa98357
Clone ID Related Accession (Same CDS sequence)	NM_207061.2
Accession Version	NM_207061.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 831bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-01-26
Organism	Danio rerio(zebrafish)
Product	toll-interacting protein isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH448242.1, EH573127.1 and EH562339.1. On Jun 18, 2016 this sequence version replaced NM_207061.1. ##Evidence-Data-START## Transcript exon combination :: EH440151.1, BC046009.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##

ATGGCGACAA CAATAAGCAC GCAACGAGGA CAGGTTTACA TCGGTGAGTT GCCTCAGGAT 
TTTCTGAGGA TCATGCCGAC TCAGCAGCAG CAGCAAGTGC AGTTAGACGC ACAGGCGGCC 
CGACAGCTGC AGTACGGAGG ATCTTTAGGC ACTGCTGGAC GCCTCAGCAT CACTGTAGTA 
CAGGCTAAGC TTGCAAAGAA CTATGGTATG ACACGGATGG ACCCTTACTG CAGGATTCGA 
CTGGGCTACG CTGTCTACGA GACTCCAACC GCTCACAATG GAGCAAAAAA CCCTCGCTGG 
AACAAAGTCA TCCAGTGCAC CGTCCCTCCC GGGGTGGACT CCTTCTATCT GGAGATATTC 
GATGAGAGGG CGTTTTCTAT GGATGATCGC ATCGCATGGA CACACGTCAC AATCCCTGAA 
AACCTGCGGG AGGGAACTGT AGTGGACGAG TGGTACAGCC TGAGCGGGAG ACAGGGGGAC 
GACAAAGAGG GCATGATTAA TCTCGTCATG TCCTTTGCAA CAATACCCGC AGGAATGATG 
ATGCAGCCGC AGCCTGTGGT TCTGATGCCT ACAGTCTATC AGCAGGGAGT CGGTTATGTG 
CCCATAGCAG GCGTCCCTGG GATGTATAAT CAGGGTGTGG TGCCCATGGG GATGCCAGCC 
GCTCCTCCAG TGGCGTCTCA GAGTGCCCCA TGCAGCGAAG AAGACCTGAA AGCCCTTCAG 
GACATGTTCC CCAACCTGGA CAAAGAGGTG ATCCGCACGG TTTTAGAGGC GCAGCAGGGA 
AATAAAGATG CTGCCATAAA CTCCCTGCTG CAGATGGCGG AGGAGCTTTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_996944.2
CDS	158..988
Translation	MATTISTQRGQVYIGELPQDFLRIMPTQQQQQVQLDAQAARQLQYGGSLGTAGRLSITVVQAKLAKNYGMTRMDPYCRIRLGYAVYETPTAHNGAKNPRWNKVIQCTVPPGVDSFYLEIFDERAFSMDDRIAWTHVTIPENLREGTVVDEWYSLSGRQGDDKEGMINLVMSFATIPAGMMMQPQPVVLMPTVYQQGVGYVPIAGVPGMYNQGVVPMGMPAAPPVASQSAPCSEEDLKALQDMFPNLDKEVIRTVLEAQQGNKDAAINSLLQMAEEL

Target ORF information:

RefSeq Version	NM_207061.2
Organism	Danio rerio(zebrafish)
Definition	Danio rerio toll interacting protein (tollip), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_207061.2

ORF Insert Sequence:

ATGGCGACAA CAATAAGCAC GCAACGAGGA CAGGTTTACA TCGGTGAGTT GCCTCAGGAT 
TTTCTGAGGA TCATGCCGAC TCAGCAGCAG CAGCAAGTGC AGTTAGACGC ACAGGCGGCC 
CGACAGCTGC AGTACGGAGG ATCTTTAGGC ACTGCTGGAC GCCTCAGCAT CACTGTAGTA 
CAGGCTAAGC TTGCAAAGAA CTATGGTATG ACACGGATGG ACCCTTACTG CAGGATTCGA 
CTGGGCTACG CTGTCTACGA GACTCCAACC GCTCACAATG GAGCAAAAAA CCCTCGCTGG 
AACAAAGTCA TCCAGTGCAC CGTCCCTCCC GGGGTGGACT CCTTCTATCT GGAGATATTC 
GATGAGAGGG CGTTTTCTAT GGATGATCGC ATCGCATGGA CACACGTCAC AATCCCTGAA 
AACCTGCGGG AGGGAACTGT AGTGGACGAG TGGTACAGCC TGAGCGGGAG ACAGGGGGAC 
GACAAAGAGG GCATGATTAA TCTCGTCATG TCCTTTGCAA CAATACCCGC AGGAATGATG 
ATGCAGCCGC AGCCTGTGGT TCTGATGCCT ACAGTCTATC AGCAGGGAGT CGGTTATGTG 
CCCATAGCAG GCGTCCCTGG GATGTATAAT CAGGGTGTGG TGCCCATGGG GATGCCAGCC 
GCTCCTCCAG TGGCGTCTCA GAGTGCCCCA TGCAGCGAAG AAGACCTGAA AGCCCTTCAG 
GACATGTTCC CCAACCTGGA CAAAGAGGTG ATCCGCACGG TTTTAGAGGC GCAGCAGGGA 
AATAAAGATG CTGCCATAAA CTCCCTGCTG CAGATGGCGG AGGAGCTTTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Evolution of complexity in the zebrafish synapse proteome.
Nature communications814613(2017 Mar)
Bay?s ?,Collins MO,Reig-Viader R,Gou G,Goulding D,Izquierdo A,Choudhary JS,Emes RD,Grant SG

Characterization and expression analysis of Toll-interacting protein in common carp, Cyprinus carpio L., responding to bacterial and viral challenge.
SpringerPlus5639(2016)
Shan S,Wang L,Zhang F,Zhu Y,An L,Yang G

Endocytic Adaptor Protein Tollip Inhibits Canonical Wnt Signaling.
PloS one10(6)e0130818(2015)
Toru? A,Szyma?ska E,Castanon I,Woli?ska-Nizio? L,Bartosik A,Jastrz?bski K,Mi?tkowska M,Gonz?lez-Gait?n M,Miaczynska M

Conservation and divergence of gene families encoding components of innate immune response systems in zebrafish.
Genome biology8(11)R251(2007)
Stein C,Caccamo M,Laird G,Leptin M

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tollip cDNA ORF clone, Danio rerio(zebrafish)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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