yy1a cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	yy1a
Entrez Gene ID	322397
Full Name	YY1 transcription factor a
Synonyms	fb59g10,wu:fa16g07,wu:fb59g10,yy1
General protein information	Preferred Names YY1 transcription factor a Names transcriptional repressor protein YY1 transcription factor Yy1
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_212617.1	NP_997782.1	transcriptional repressor protein YY1
NM_212617.2	NP_997782.1	transcriptional repressor protein YY1

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	YY1	NP_001026381.1
Bos taurus (cattle)	YY1	NP_001091550.1
Rattus norvegicus (Norway rat)	Yy1	NP_775412.1
Danio rerio (zebrafish)	yy1a	NP_997782.1
Xenopus tropicalis (tropical clawed frog)	yy1	NP_001116880.1
Mus musculus (house mouse)	Yy1	NP_033563.2
Canis lupus familiaris (dog)	YY1	XP_854514.1
Homo sapiens (human)	YY1	NP_003394.1
Pan troglodytes (chimpanzee)	YY1	XP_510162.3

Gene Ontology
Bibliography

Related articles in PubMed

Competitive binding between Seryl-tRNA synthetase/YY1 complex and NFKB1 at the distal segment results in differential regulation of human vegfa promoter activity during angiogenesis.
Fu CY, Wang PC, Tsai HJ
Nucleic acids research45(5)2423-2437(2017 Mar)

Knockdown of zebrafish YY1a can downregulate the phosphatidylserine (PS) receptor expression, leading to induce the abnormal brain and heart development.
Shiu WL, Huang KR, Hung JC, Wu JL, Hong JR
Journal of biomedical science2331(2016 Feb)

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

Ubiquitous transcription factor YY1 promotes zebrafish liver steatosis and lipotoxicity by inhibiting CHOP-10 expression.
Her GM, Pai WY, Lai CY, Hsieh YW, Pang HW
Biochimica et biophysica acta1831(6)1037-51(2013 Jun)

A comparative expression analysis of gene transcripts in brain tissue of non-transgenic and GH-transgenic zebrafish (Danio rerio) using a DDRT-PCR approach.
Alves-Costa FA, Figueiredo MA, Lanes CF, Almeida DV, Marins LF, Wasko AP
Anais da Academia Brasileira de Ciencias84(2)487-94(2012 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

results suggest that YY1a regulates PS receptor expression that linked to function of PSR-phagocyte mediated apoptotic cell engulfment during development
Title: Knockdown of zebrafish YY1a can downregulate the phosphatidylserine (PS) receptor expression, leading to induce the abnormal brain and heart development.

YY1 promotes zebrafish liver steatosis and lipotoxicity by inhibiting CHOP-10 expression.
Title: Ubiquitous transcription factor YY1 promotes zebrafish liver steatosis and lipotoxicity by inhibiting CHOP-10 expression.

Study demonstrated that beta-arrestin1 is critically involved in zebrafish primitive hematopoiesis, where beta-arrestin1 binds to and sequesters the PcG recruiter YY1, thus relieving PcG-mediated repression of cdx4-hox pathway.
Title: Beta-arrestin1 regulates zebrafish hematopoiesis through binding to YY1 and relieving polycomb group repression.

The following yy1a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the yy1a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa35151	NM_212617.1 Latest version!	Danio rerio YY1 transcription factor a (yy1a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00
ODa141167	NM_212617.2 Latest version!	Danio rerio YY1 transcription factor a (yy1a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$258.30 $369.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

yy1a ( NM_212617.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_997782.1 Danio rerio YY1 transcription factor a (yy1a), mRNA.

Price & Availability↑

CloneID	ODa35151
Clone ID Related Accession (Same CDS sequence)	NM_212617.1
Accession Version	NM_212617.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1074bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-25
Organism	Danio rerio(Zebrafish)
Product	transcriptional repressor protein YY1
Comment	PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF389345.1. ##Evidence-Data-START## CDS exon combination :: AF389345.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMEA2168446, SAMEA2168447 [ECO:0000350] ##Evidence-Data-END##

ATGGCGTCGG GCGAGACACT GTACATCGAG GCCGACGGCT CGGAAATGCC GGCCGAGATC 
GTCGAGCTGC ACGAAATCGA AGTTGAGACT ATCGAGACCA CAGTGGTCGG CGGAGACGAC 
GACGAGCACC AGCCCATGAT CGCCCTGCAG CCGCTGGTCA CGGACGACCC GAACCACGTT 
AACCACCAGG AGGTGATTTT AGTGCAAACT CGTGAAGAGG TGGTGGGTTG CGATGACTCG 
GACCTCCATG CAGACGACAG TTTCGAGGAC CAGATCCTCA TTCCCGTGCC CGTTCCGGTG 
GCAGAGGAGG AATATATCGA GCAGACTTTA GTGACCGTGT CTGGCAAGAA TCCGTCTGGT 
AGGATGAAGA AAGGAGGAGG CAGTGGGAAA AGAGTGGTCA AAAAGAGCTT CCTAAACTCC 
GCTGAAGCGA GCGGACGCAA ATGGGAGCAG AAACAAGTAC AGATCAAAAC ACTGGAGGGG 
GAGTTTTCCG TCACTATGTG GGCATCGGAT GATAAGAAAG ATGTTGATCA TGAGACAGTG 
GTGGAGGAGC AGATCATTGG AGAAAACTCT CCTCCAGATT ATTCAGAATA CATGACAGGC 
AAGAAACTGC CACCTGGTGG CATACCCGGC ATTGACCTGT CAGACCCAAA ACAGCTGGCA 
GAGTTTGCCA GAATGAAGCC TAGGAAAATA AAAGAAGATG ATTCTCCAAG GACGATAGCT 
TGCCCACACA AAGGTTGCAC AAAAATGTTT CGGGATAACT CCGCTATGAG GAAGCACTTG 
CACACCCACG GGCCGCGGGT TCACGTCTGC GCTGAATGTG GGAAGGCGTT TGTGGAAAGT 
TCCAAGCTAA AACGGCATCA GTTGGTTCAT ACTGGTGAAA AACCTTTCCA GTGCACATTT 
GAGGGATGTG GAAAGCGCTT CTCATTGGAC TTTAACTTGC GCACACATGT GCGGATTCAC 
ACTGGAGACA GACCGTACGT TTGCCCGTTC GATGGCTGTA ACAAGAAATT TGCTCAGTCC 
ACCAACCTGA AGTCTCACAT TTTGACACAC GCGAAAGCTA AGAACAATCA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_997782.1
CDS	988..2061
Translation	MASGETLYIEADGSEMPAEIVELHEIEVETIETTVVGGDDDEHQPMIALQPLVTDDPNHVNHQEVILVQTREEVVGCDDSDLHADDSFEDQILIPVPVPVAEEEYIEQTLVTVSGKNPSGRMKKGGGSGKRVVKKSFLNSAEASGRKWEQKQVQIKTLEGEFSVTMWASDDKKDVDHETVVEEQIIGENSPPDYSEYMTGKKLPPGGIPGIDLSDPKQLAEFARMKPRKIKEDDSPRTIACPHKGCTKMFRDNSAMRKHLHTHGPRVHVCAECGKAFVESSKLKRHQLVHTGEKPFQCTFEGCGKRFSLDFNLRTHVRIHTGDRPYVCPFDGCNKKFAQSTNLKSHILTHAKAKNNQ

Target ORF information:

RefSeq Version	NM_212617.1
Organism	Danio rerio(Zebrafish)
Definition	Danio rerio YY1 transcription factor a (yy1a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_212617.1

ORF Insert Sequence:

ATGGCGTCGG GCGAGACACT GTACATCGAG GCCGACGGCT CGGAAATGCC GGCCGAGATC 
GTCGAGCTGC ACGAAATCGA AGTTGAGACT ATCGAGACCA CAGTGGTCGG CGGAGACGAC 
GACGAGCACC AGCCCATGAT CGCCCTGCAG CCGCTGGTCA CGGACGACCC GAACCACGTT 
AACCACCAGG AGGTGATTTT AGTGCAAACT CGTGAAGAGG TGGTGGGTTG CGATGACTCG 
GACCTCCATG CAGACGACAG TTTCGAGGAC CAGATCCTCA TTCCCGTGCC CGTTCCGGTG 
GCAGAGGAGG AATATATCGA GCAGACTTTA GTGACCGTGT CTGGCAAGAA TCCGTCTGGT 
AGGATGAAGA AAGGAGGAGG CAGTGGGAAA AGAGTGGTCA AAAAGAGCTT CCTAAACTCC 
GCTGAAGCGA GCGGACGCAA ATGGGAGCAG AAACAAGTAC AGATCAAAAC ACTGGAGGGG 
GAGTTTTCCG TCACTATGTG GGCATCGGAT GATAAGAAAG ATGTTGATCA TGAGACAGTG 
GTGGAGGAGC AGATCATTGG AGAAAACTCT CCTCCAGATT ATTCAGAATA CATGACAGGC 
AAGAAACTGC CACCTGGTGG CATACCCGGC ATTGACCTGT CAGACCCAAA ACAGCTGGCA 
GAGTTTGCCA GAATGAAGCC TAGGAAAATA AAAGAAGATG ATTCTCCAAG GACGATAGCT 
TGCCCACACA AAGGTTGCAC AAAAATGTTT CGGGATAACT CCGCTATGAG GAAGCACTTG 
CACACCCACG GGCCGCGGGT TCACGTCTGC GCTGAATGTG GGAAGGCGTT TGTGGAAAGT 
TCCAAGCTAA AACGGCATCA GTTGGTTCAT ACTGGTGAAA AACCTTTCCA GTGCACATTT 
GAGGGATGTG GAAAGCGCTT CTCATTGGAC TTTAACTTGC GCACACATGT GCGGATTCAC 
ACTGGAGACA GACCGTACGT TTGCCCGTTC GATGGCTGTA ACAAGAAATT TGCTCAGTCC 
ACCAACCTGA AGTCTCACAT TTTGACACAC GCGAAAGCTA AGAACAATCA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

yy1a ( NM_212617.2 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_997782.1 Danio rerio YY1 transcription factor a (yy1a), mRNA.

Price & Availability↑

CloneID	ODa141167
Clone ID Related Accession (Same CDS sequence)	NM_212617.2
Accession Version	NM_212617.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1074bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-11-23
Organism	Danio rerio(zebrafish)
Product	transcriptional repressor protein YY1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX546455.6. On May 31, 2017 this sequence version replaced NM_212617.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC071351.1, GDQQ01005365.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2168446, SAMEA2168447 [ECO:0000350] ##Evidence-Data-END##

ATGGCGTCGG GCGAGACACT GTACATCGAG GCCGACGGCT CGGAAATGCC GGCCGAGATC 
GTCGAGCTGC ACGAAATCGA AGTTGAGACT ATCGAGACCA CAGTGGTCGG CGGAGACGAC 
GACGAGCACC AGCCCATGAT CGCCCTGCAG CCGCTGGTCA CGGACGACCC GAACCACGTT 
AACCACCAGG AGGTGATTTT AGTGCAAACT CGTGAAGAGG TGGTGGGTTG CGATGACTCG 
GACCTCCATG CAGACGACAG TTTCGAGGAC CAGATCCTCA TTCCCGTGCC CGTTCCGGTG 
GCAGAGGAGG AATATATCGA GCAGACTTTA GTGACCGTGT CTGGCAAGAA TCCGTCTGGT 
AGGATGAAGA AAGGAGGAGG CAGTGGGAAA AGAGTGGTCA AAAAGAGCTT CCTAAACTCC 
GCTGAAGCGA GCGGACGCAA ATGGGAGCAG AAACAAGTGC AGATCAAAAC ACTGGAGGGG 
GAGTTTTCCG TCACTATGTG GGCATCGGAT GATAAGAAAG ATGTTGATCA TGAGACAGTG 
GTGGAGGAGC AGATCATTGG AGAAAACTCT CCTCCAGATT ATTCAGAATA CATGACAGGC 
AAGAAACTGC CACCTGGTGG CATACCCGGC ATTGACCTGT CAGACCCCAA ACAGCTGGCA 
GAGTTTGCCA GAATGAAGCC TAGGAAAATA AAAGAAGATG ATTCTCCAAG GACGATAGCT 
TGCCCACACA AAGGTTGCAC AAAAATGTTT CGGGATAACT CCGCTATGAG GAAGCACTTG 
CACACCCACG GGCCGCGGGT TCACGTCTGC GCTGAATGTG GGAAGGCGTT TGTGGAAAGT 
TCCAAGCTAA AACGGCATCA GTTGGTTCAT ACTGGTGAAA AACCTTTCCA GTGCACATTT 
GAGGGATGTG GAAAGCGCTT CTCATTGGAC TTTAACTTGC GCACACATGT GCGGATTCAC 
ACTGGAGACA GACCGTACGT TTGCCCGTTC GATGGCTGTA ACAAGAAATT TGCTCAGTCC 
ACCAACCTGA AGTCTCACAT TTTGACACAC GCGAAAGCTA AGAACAATCA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_997782.1
CDS	117..1190
Translation	MASGETLYIEADGSEMPAEIVELHEIEVETIETTVVGGDDDEHQPMIALQPLVTDDPNHVNHQEVILVQTREEVVGCDDSDLHADDSFEDQILIPVPVPVAEEEYIEQTLVTVSGKNPSGRMKKGGGSGKRVVKKSFLNSAEASGRKWEQKQVQIKTLEGEFSVTMWASDDKKDVDHETVVEEQIIGENSPPDYSEYMTGKKLPPGGIPGIDLSDPKQLAEFARMKPRKIKEDDSPRTIACPHKGCTKMFRDNSAMRKHLHTHGPRVHVCAECGKAFVESSKLKRHQLVHTGEKPFQCTFEGCGKRFSLDFNLRTHVRIHTGDRPYVCPFDGCNKKFAQSTNLKSHILTHAKAKNNQ

Target ORF information:

RefSeq Version	NM_212617.2
Organism	Danio rerio(zebrafish)
Definition	Danio rerio YY1 transcription factor a (yy1a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_212617.2

ORF Insert Sequence:

ATGGCGTCGG GCGAGACACT GTACATCGAG GCCGACGGCT CGGAAATGCC GGCCGAGATC 
GTCGAGCTGC ACGAAATCGA AGTTGAGACT ATCGAGACCA CAGTGGTCGG CGGAGACGAC 
GACGAGCACC AGCCCATGAT CGCCCTGCAG CCGCTGGTCA CGGACGACCC GAACCACGTT 
AACCACCAGG AGGTGATTTT AGTGCAAACT CGTGAAGAGG TGGTGGGTTG CGATGACTCG 
GACCTCCATG CAGACGACAG TTTCGAGGAC CAGATCCTCA TTCCCGTGCC CGTTCCGGTG 
GCAGAGGAGG AATATATCGA GCAGACTTTA GTGACCGTGT CTGGCAAGAA TCCGTCTGGT 
AGGATGAAGA AAGGAGGAGG CAGTGGGAAA AGAGTGGTCA AAAAGAGCTT CCTAAACTCC 
GCTGAAGCGA GCGGACGCAA ATGGGAGCAG AAACAAGTGC AGATCAAAAC ACTGGAGGGG 
GAGTTTTCCG TCACTATGTG GGCATCGGAT GATAAGAAAG ATGTTGATCA TGAGACAGTG 
GTGGAGGAGC AGATCATTGG AGAAAACTCT CCTCCAGATT ATTCAGAATA CATGACAGGC 
AAGAAACTGC CACCTGGTGG CATACCCGGC ATTGACCTGT CAGACCCCAA ACAGCTGGCA 
GAGTTTGCCA GAATGAAGCC TAGGAAAATA AAAGAAGATG ATTCTCCAAG GACGATAGCT 
TGCCCACACA AAGGTTGCAC AAAAATGTTT CGGGATAACT CCGCTATGAG GAAGCACTTG 
CACACCCACG GGCCGCGGGT TCACGTCTGC GCTGAATGTG GGAAGGCGTT TGTGGAAAGT 
TCCAAGCTAA AACGGCATCA GTTGGTTCAT ACTGGTGAAA AACCTTTCCA GTGCACATTT 
GAGGGATGTG GAAAGCGCTT CTCATTGGAC TTTAACTTGC GCACACATGT GCGGATTCAC 
ACTGGAGACA GACCGTACGT TTGCCCGTTC GATGGCTGTA ACAAGAAATT TGCTCAGTCC 
ACCAACCTGA AGTCTCACAT TTTGACACAC GCGAAAGCTA AGAACAATCA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Competitive binding between Seryl-tRNA synthetase/YY1 complex and NFKB1 at the distal segment results in differential regulation of human vegfa promoter activity during angiogenesis.
Nucleic acids research45(5)2423-2437(2017 Mar)
Fu CY,Wang PC,Tsai HJ

Knockdown of zebrafish YY1a can downregulate the phosphatidylserine (PS) receptor expression, leading to induce the abnormal brain and heart development.
Journal of biomedical science2331(2016 Feb)
Shiu WL,Huang KR,Hung JC,Wu JL,Hong JR

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

Ubiquitous transcription factor YY1 promotes zebrafish liver steatosis and lipotoxicity by inhibiting CHOP-10 expression.
Biochimica et biophysica acta1831(6)1037-51(2013 Jun)
Her GM,Pai WY,Lai CY,Hsieh YW,Pang HW

A comparative expression analysis of gene transcripts in brain tissue of non-transgenic and GH-transgenic zebrafish (Danio rerio) using a DDRT-PCR approach.
Anais da Academia Brasileira de Ciencias84(2)487-94(2012 Jun)
Alves-Costa FA,Figueiredo MA,Lanes CF,Almeida DV,Marins LF,Wasko AP

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yy1a cDNA ORF clone, Danio rerio(zebrafish)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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