psen1 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	psen1
Entrez Gene ID	30221
Full Name	presenilin 1
Synonyms	pre1,psen,zf-PS1,zfPS1
General protein information	Preferred Names presenilin 1 Names presenilin-1 PS-1
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
XM_005169882.3	XP_005169939.1	presenilin-1 isoform X1
XM_005169882.4	XP_005169939.1	presenilin-1 isoform X1
XM_005169883.3	XP_005169940.1	presenilin-1 isoform X2
XM_005169883.4	XP_005169940.1	presenilin-1 isoform X2
NM_131024.1	NP_571099.1	presenilin-1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	PSEN1	XP_001150037.1
Canis lupus familiaris (dog)	PSEN1	NP_001002943.1
	PSEN1	XP_001088635.1
Rattus norvegicus (Norway rat)	Psen1	NP_062036.2
Arabidopsis thaliana (thale cress)	PS1	NP_172346.1
Homo sapiens (human)	PSEN1	NP_000012.1
Bos taurus (cattle)	PSEN1	NP_777146.1
Gallus gallus (chicken)	PSEN1	NP_989494.1
Arabidopsis thaliana (thale cress)	PS2	NP_180551.1
Mus musculus (house mouse)	Psen1	NP_032969.1
Danio rerio (zebrafish)	psen1	NP_571099.1
Caenorhabditis elegans (roundworm)	sel-12	NP_508175.1
Oryza sativa (rice)	Os03g0603700	NP_001173529.1
Xenopus tropicalis (tropical clawed frog)	psen1	NP_001027027.1

Gene Ontology
Bibliography

Related articles in PubMed

Mitochondrion to endoplasmic reticulum apposition length in zebrafish embryo spinal progenitors is unchanged in response to perturbations associated with Alzheimer's disease.
Newman M, Halter L, Lim A, Lardelli M
PloS one12(6)e0179859(2017)

Transcriptomic profiling of mTOR and ryanodine receptor signaling molecules in developing zebrafish in the absence and presence of PCB 95.
Frank DF, Miller GW, Connon RE, Geist J, Lein PJ
PeerJ5e4106(2017)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Using an antisense morpholino oligonucleotide, study blocked induction of PS1IV isoform that normally occurs under hypoxia,identified gene regulatory networks that are modulated by PS1IV: observed changes in expression of genes controlling inflammation, vascular development, the UPR, protein synthesis, calcium homeostasis, catecholamine biosynthesis, TOR signaling, and cell proliferation
Title: The Zebrafish Equivalent of Alzheimer's Disease-Associated PRESENILIN Isoform PS2V Regulates Inflammatory and Other Responses to Hypoxic Stress.

Both human PS2V and zebrafish PS1IV can stimulate gamma-secretase activity despite extreme structural divergence.
Title: Alzheimer's disease-related peptide PS2V plays ancient, conserved roles in suppression of the unfolded protein response under hypoxia and stimulation of ?-secretase activity.

We identified psen1 as a regulator of the development of histaminergic neurons in zebrafish
Title: Presenilin1 regulates histamine neuron development and behavior in zebrafish, danio rerio.

We now demonstrate that zebrafish embryos maintain relatively stable levels of normal Presenilin1 transcript and protein despite accumulating large amounts of aberrantly spliced presenilin1 transcript.
Title: Robust homeostasis of Presenilin1 protein levels by transcript regulation.

These results suggest that Psen2 plays a more prominent role in Notch signalling and embryo development in zebrafish than in mammals, and that the effect of reduced Psen2 can be ameliorated by Psen1 loss.
Title: Independent and cooperative action of Psen2 with Psen1 in zebrafish embryos.

The following psen1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the psen1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ODa02257	NM_131024.1 Latest version!	Danio rerio presenilin 1 (psen1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00
ODa22937	XM_005169882.4 Latest version!	Danio rerio presenilin 1 (psen1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00
ODa22938	XM_005169883.4 Latest version!	Danio rerio presenilin 1 (psen1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00
View Old Accession Versions >>
ODa22937	XM_005169882.3	Danio rerio presenilin 1 (psen1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00
ODa22938	XM_005169883.3	Danio rerio presenilin 1 (psen1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

psen1 ( NM_131024.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_571099.1 Danio rerio presenilin 1 (psen1), mRNA.

Price & Availability↑

CloneID	ODa02257
Clone ID Related Accession (Same CDS sequence)	NM_131024.1
Accession Version	NM_131024.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1371bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Danio rerio(zebrafish)
Product	presenilin-1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ132931.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ132931.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2168446, SAMEA2168447 [ECO:0000350] ##Evidence-Data-END##

ATGGCTGATT TAGTGCAGAA TGCTGCCAAT AATGTGTTAA ATGATGGGAT GGACACCAGC 
CGGCACACAA GCAGCACCGC GGCGCCGCCC AGCCGTAATG AGGTGGAGCT GAACGGGCAG 
CCGCCCACCG CTCCGCCCCC GCAGGTGGTC ACAGACAGTG AGGAAGACGA GGACGAGGAG 
CTCACTCTCA AATATGGGGC GAAGCACGTC ATCATGCTGT TCATTCCCGT CACGCTCTGC 
ATGGTGGTGG TGGTGGCGAC CATCAAATCC GTCAGCTTCT ACACGCAGAA GGACGGACAG 
CAGCTGATCT ACACCCCGTT TCGTGAGGAC ACGGAGACGG TGGGTCAGCG AGCTCTGCAC 
TCCATGCTCA ACGCCATCAT CATGATCAGT GTGATTGTGG TCATGACCCT GGTGCTGGTG 
GTGCTCTACA AGTACAGATG CTACAAGGTG ATTCAAGCCT GGCTGTTCTT CTCCAACCTC 
CTCCTGCTCT TCTTTTTCTC CTTAATTTAT TTGGGGGAAG TGTTCAAGAC GTATAACGTG 
GCGATGGATT ACTTCACGCT GGCGTTGATC ATCTGGAACT TCGGTGTGGT GGGAATGATC 
TGCATCCACT GGAAGGGGCC GCTGCGGCTT CAGCAGGCCT ATCTGATCAT GATCAGCGCT 
CTCATGGCTC TGGTCTTCAT CAAATATCTC CCCGAGTGGA CCGCATGGCT CATCCTCGCT 
GCTATTTCAG TCTACGATCT TCTGGCAGTG TTGTGTCCGA AAGGCCCTCT GCGAATCCTT 
GTGGAAACGG CTCAAGAGAG GAATGAGGCC ATTTTCCCAG CGCTCATCTA CTCCTCTACG 
ATGGTGTGGC TCTTCAATAT GGCGGACAGT GCTGAAACCA GGAATAATTC CAGTCATCCA 
GTCCCTCAGC AGGAGAACCA GGTAGTTGCG ATGGCTCCCA CAGCTCAGGC GGAGGACGAT 
GGCGGCTTCA CTCCGGCGTG GGTGGATCAT CAGCAGCATC AGCTCGGACC CATGCAGTCC 
ACGGAGGAGA GCAGACGACA GATCCAGGAG ATGCCCAGCG CTCGGCCACC ACCACCAGCA 
GATGATGACG AAGAGCGGGG TGTGAAGCTG GGTTTGGGAG ATTTCATCTT TTACAGTATG 
CTGGTGGGTA AAGCATCAGC TACAGCCAGC GGTGACTGGA ACACGACGCT AGCCTGCTTC 
GTGGCCATTC TCATTGGTTT ATGTCTGACT CTCCTCCTGC TGGCCATCTT CAAGAAGGCT 
CTTCCCGCTC TCCCCATCTC CATAACCTTC GGCCTGGTGT TTTACTTTGC CACTGATAAC 
CTCGTGCGGC CGTTCATGGA CCAGCTGGCC GTCCATCAGT TCTACATATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_571099.1
CDS	62..1432
Translation	MADLVQNAANNVLNDGMDTSRHTSSTAAPPSRNEVELNGQPPTAPPPQVVTDSEEDEDEELTLKYGAKHVIMLFIPVTLCMVVVVATIKSVSFYTQKDGQQLIYTPFREDTETVGQRALHSMLNAIIMISVIVVMTLVLVVLYKYRCYKVIQAWLFFSNLLLLFFFSLIYLGEVFKTYNVAMDYFTLALIIWNFGVVGMICIHWKGPLRLQQAYLIMISALMALVFIKYLPEWTAWLILAAISVYDLLAVLCPKGPLRILVETAQERNEAIFPALIYSSTMVWLFNMADSAETRNNSSHPVPQQENQVVAMAPTAQAEDDGGFTPAWVDHQQHQLGPMQSTEESRRQIQEMPSARPPPPADDDEERGVKLGLGDFIFYSMLVGKASATASGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFATDNLVRPFMDQLAVHQFYI

Target ORF information:

RefSeq Version	NM_131024.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio presenilin 1 (psen1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_131024.1

ORF Insert Sequence:

ATGGCTGATT TAGTGCAGAA TGCTGCCAAT AATGTGTTAA ATGATGGGAT GGACACCAGC 
CGGCACACAA GCAGCACCGC GGCGCCGCCC AGCCGTAATG AGGTGGAGCT GAACGGGCAG 
CCGCCCACCG CTCCGCCCCC GCAGGTGGTC ACAGACAGTG AGGAAGACGA GGACGAGGAG 
CTCACTCTCA AATATGGGGC GAAGCACGTC ATCATGCTGT TCATTCCCGT CACGCTCTGC 
ATGGTGGTGG TGGTGGCGAC CATCAAATCC GTCAGCTTCT ACACGCAGAA GGACGGACAG 
CAGCTGATCT ACACCCCGTT TCGTGAGGAC ACGGAGACGG TGGGTCAGCG AGCTCTGCAC 
TCCATGCTCA ACGCCATCAT CATGATCAGT GTGATTGTGG TCATGACCCT GGTGCTGGTG 
GTGCTCTACA AGTACAGATG CTACAAGGTG ATTCAAGCCT GGCTGTTCTT CTCCAACCTC 
CTCCTGCTCT TCTTTTTCTC CTTAATTTAT TTGGGGGAAG TGTTCAAGAC GTATAACGTG 
GCGATGGATT ACTTCACGCT GGCGTTGATC ATCTGGAACT TCGGTGTGGT GGGAATGATC 
TGCATCCACT GGAAGGGGCC GCTGCGGCTT CAGCAGGCCT ATCTGATCAT GATCAGCGCT 
CTCATGGCTC TGGTCTTCAT CAAATATCTC CCCGAGTGGA CCGCATGGCT CATCCTCGCT 
GCTATTTCAG TCTACGATCT TCTGGCAGTG TTGTGTCCGA AAGGCCCTCT GCGAATCCTT 
GTGGAAACGG CTCAAGAGAG GAATGAGGCC ATTTTCCCAG CGCTCATCTA CTCCTCTACG 
ATGGTGTGGC TCTTCAATAT GGCGGACAGT GCTGAAACCA GGAATAATTC CAGTCATCCA 
GTCCCTCAGC AGGAGAACCA GGTAGTTGCG ATGGCTCCCA CAGCTCAGGC GGAGGACGAT 
GGCGGCTTCA CTCCGGCGTG GGTGGATCAT CAGCAGCATC AGCTCGGACC CATGCAGTCC 
ACGGAGGAGA GCAGACGACA GATCCAGGAG ATGCCCAGCG CTCGGCCACC ACCACCAGCA 
GATGATGACG AAGAGCGGGG TGTGAAGCTG GGTTTGGGAG ATTTCATCTT TTACAGTATG 
CTGGTGGGTA AAGCATCAGC TACAGCCAGC GGTGACTGGA ACACGACGCT AGCCTGCTTC 
GTGGCCATTC TCATTGGTTT ATGTCTGACT CTCCTCCTGC TGGCCATCTT CAAGAAGGCT 
CTTCCCGCTC TCCCCATCTC CATAACCTTC GGCCTGGTGT TTTACTTTGC CACTGATAAC 
CTCGTGCGGC CGTTCATGGA CCAGCTGGCC GTCCATCAGT TCTACATATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

psen1 ( XM_005169882.3 ) cDNA ORF clone, Danio rerio(zebrafish) -> XP_005169939.1 Danio rerio presenilin 1 (psen1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ODa22937
Clone ID Related Accession (Same CDS sequence)	XM_005169882.3 , XM_005169882.4
Accession Version	XM_005169882.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1371bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-23
Organism	Danio rerio(Zebrafish)
Product	presenilin-1 isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_007128.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 24, 2016 this sequence version replaced XM_005169882.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Danio rerio Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGATT TAGTGCAGAA TGCTGCCAAT AATGTGCTAA ATGATGGGAT GGACACCAGC 
CGGCACACAA GCAGCACCGC GGCGCCGCCC AGCCGTAATG AGGTGGAGCT GAACGGGCAG 
CCGCCCACCG CTCCGCCCCC GCAGGTGGTC ACAGACAGTG AGGAAGACGA GGACGAGGAG 
CTCACTCTCA AATATGGGGC GAAGCACGTC ATCATGCTGT TCATTCCCGT CACGCTCTGC 
ATGGTGGTGG TGGTGGCGAC CATCAAATCT GTCAGCTTCT ACACACAGAA GGACGGACAG 
CAGCTGATCT ACACCCCGTT TCGTGAGGAC ACGGAGACGG TGGGTCAGCG AGCTCTGCAC 
TCCATGCTCA ACGCCATCAT CATGATCAGT GTGATCGTGG TCATGACCCT GGTGCTGGTG 
GTGCTCTACA AGTACAGATG CTACAAGGTG ATTCAAGCCT GGCTGTTCTT CTCCAACCTC 
CTCCTGCTCT TCTTTTTCTC CTTAATTTAT TTGGGGGAAG TGTTCAAGAC GTATAACGTG 
GCGATGGATT ACTTCACGCT GGCGTTGATC ATCTGGAACT TCGGTGTGGT GGGAATGATC 
TGCATCCACT GGAAGGGGCC GCTGCGGCTC CAGCAGGCCT ATCTGATCAT GATCAGCGCT 
CTCATGGCTC TGGTCTTCAT CAAGTATCTC CCCGAGTGGA CCGCATGGCT CATCCTCGCT 
GCTATTTCAG TCTACGATCT TCTGGCAGTG TTGTGTCCGA AAGGCCCTCT GCGAATCCTT 
GTGGAAACAG CTCAAGAGAG GAATGAGGCC ATTTTCCCAG CGCTCATCTA CTCCTCTACG 
ATGGTGTGGC TCTTCAATAT GGCGGACAGT GCTGAAACCA GGAATAATTC CAGTCATCCA 
GTCCCTCAGC AGGAGAACCA GGTAGTTGCG ATGGCTCCCA CAGCTCAGCC GGAGGACGAT 
GGCGGCTTCA CTCCGGCGTG GGTGGATCAT CAGCAGCATC AGCTCGGACC CATGCAGTCC 
ACGGAGGAGA GCAGACGACA GATCCAGGAG ATGCCCAGCG CTCGGCCACC ACCACCAGCA 
GATGATGACG AAGAGCGGGG TGTGAAGCTG GGTTTGGGAG ATTTCATCTT TTACAGTATG 
CTGGTGGGTA AAGCATCAGC TACAGCCAGC GGTGACTGGA ACACGACGTT AGCCTGCTTC 
GTGGCCATTC TCATTGGTTT ATGTCTGACT CTCCTCCTGC TGGCCATCTT CAAGAAGGCT 
CTTCCCGCAC TCCCCATCTC CATAACCTTC GGCCTGGTGT TTTACTTTGC CACTGATAAC 
CTCGTGCGGC CGTTCATGGA CCAGCTGGCC GTCCATCAGT TCTACATATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005169939.1
CDS	130..1500
Translation	MADLVQNAANNVLNDGMDTSRHTSSTAAPPSRNEVELNGQPPTAPPPQVVTDSEEDEDEELTLKYGAKHVIMLFIPVTLCMVVVVATIKSVSFYTQKDGQQLIYTPFREDTETVGQRALHSMLNAIIMISVIVVMTLVLVVLYKYRCYKVIQAWLFFSNLLLLFFFSLIYLGEVFKTYNVAMDYFTLALIIWNFGVVGMICIHWKGPLRLQQAYLIMISALMALVFIKYLPEWTAWLILAAISVYDLLAVLCPKGPLRILVETAQERNEAIFPALIYSSTMVWLFNMADSAETRNNSSHPVPQQENQVVAMAPTAQPEDDGGFTPAWVDHQQHQLGPMQSTEESRRQIQEMPSARPPPPADDDEERGVKLGLGDFIFYSMLVGKASATASGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFATDNLVRPFMDQLAVHQFYI

Target ORF information:

RefSeq Version	XM_005169882.3
Organism	Danio rerio(Zebrafish)
Definition	Danio rerio presenilin 1 (psen1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005169882.3

ORF Insert Sequence:

ATGGCTGATT TAGTGCAGAA TGCTGCCAAT AATGTGCTAA ATGATGGGAT GGACACCAGC 
CGGCACACAA GCAGCACCGC GGCGCCGCCC AGCCGTAATG AGGTGGAGCT GAACGGGCAG 
CCGCCCACCG CTCCGCCCCC GCAGGTGGTC ACAGACAGTG AGGAAGACGA GGACGAGGAG 
CTCACTCTCA AATATGGGGC GAAGCACGTC ATCATGCTGT TCATTCCCGT CACGCTCTGC 
ATGGTGGTGG TGGTGGCGAC CATCAAATCT GTCAGCTTCT ACACACAGAA GGACGGACAG 
CAGCTGATCT ACACCCCGTT TCGTGAGGAC ACGGAGACGG TGGGTCAGCG AGCTCTGCAC 
TCCATGCTCA ACGCCATCAT CATGATCAGT GTGATCGTGG TCATGACCCT GGTGCTGGTG 
GTGCTCTACA AGTACAGATG CTACAAGGTG ATTCAAGCCT GGCTGTTCTT CTCCAACCTC 
CTCCTGCTCT TCTTTTTCTC CTTAATTTAT TTGGGGGAAG TGTTCAAGAC GTATAACGTG 
GCGATGGATT ACTTCACGCT GGCGTTGATC ATCTGGAACT TCGGTGTGGT GGGAATGATC 
TGCATCCACT GGAAGGGGCC GCTGCGGCTC CAGCAGGCCT ATCTGATCAT GATCAGCGCT 
CTCATGGCTC TGGTCTTCAT CAAGTATCTC CCCGAGTGGA CCGCATGGCT CATCCTCGCT 
GCTATTTCAG TCTACGATCT TCTGGCAGTG TTGTGTCCGA AAGGCCCTCT GCGAATCCTT 
GTGGAAACAG CTCAAGAGAG GAATGAGGCC ATTTTCCCAG CGCTCATCTA CTCCTCTACG 
ATGGTGTGGC TCTTCAATAT GGCGGACAGT GCTGAAACCA GGAATAATTC CAGTCATCCA 
GTCCCTCAGC AGGAGAACCA GGTAGTTGCG ATGGCTCCCA CAGCTCAGCC GGAGGACGAT 
GGCGGCTTCA CTCCGGCGTG GGTGGATCAT CAGCAGCATC AGCTCGGACC CATGCAGTCC 
ACGGAGGAGA GCAGACGACA GATCCAGGAG ATGCCCAGCG CTCGGCCACC ACCACCAGCA 
GATGATGACG AAGAGCGGGG TGTGAAGCTG GGTTTGGGAG ATTTCATCTT TTACAGTATG 
CTGGTGGGTA AAGCATCAGC TACAGCCAGC GGTGACTGGA ACACGACGTT AGCCTGCTTC 
GTGGCCATTC TCATTGGTTT ATGTCTGACT CTCCTCCTGC TGGCCATCTT CAAGAAGGCT 
CTTCCCGCAC TCCCCATCTC CATAACCTTC GGCCTGGTGT TTTACTTTGC CACTGATAAC 
CTCGTGCGGC CGTTCATGGA CCAGCTGGCC GTCCATCAGT TCTACATATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

psen1 ( XM_005169882.4 ) cDNA ORF clone, Danio rerio(zebrafish) -> XP_005169939.1 Danio rerio presenilin 1 (psen1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ODa22937
Clone ID Related Accession (Same CDS sequence)	XM_005169882.3 , XM_005169882.4
Accession Version	XM_005169882.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1371bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-06-14
Organism	Danio rerio(zebrafish)
Product	presenilin-1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_007128.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 15, 2017 this sequence version replaced XM_005169882.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Danio rerio Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGATT TAGTGCAGAA TGCTGCCAAT AATGTGCTAA ATGATGGGAT GGACACCAGC 
CGGCACACAA GCAGCACCGC GGCGCCGCCC AGCCGTAATG AGGTGGAGCT GAACGGGCAG 
CCGCCCACCG CTCCGCCCCC GCAGGTGGTC ACAGACAGTG AGGAAGACGA GGACGAGGAG 
CTCACTCTCA AATATGGGGC GAAGCACGTC ATCATGCTGT TCATTCCCGT CACGCTCTGC 
ATGGTGGTGG TGGTGGCGAC CATCAAATCT GTCAGCTTCT ACACACAGAA GGACGGACAG 
CAGCTGATCT ACACCCCGTT TCGTGAGGAC ACGGAGACGG TGGGTCAGCG AGCTCTGCAC 
TCCATGCTCA ACGCCATCAT CATGATCAGT GTGATCGTGG TCATGACCCT GGTGCTGGTG 
GTGCTCTACA AGTACAGATG CTACAAGGTG ATTCAAGCCT GGCTGTTCTT CTCCAACCTC 
CTCCTGCTCT TCTTTTTCTC CTTAATTTAT TTGGGGGAAG TGTTCAAGAC GTATAACGTG 
GCGATGGATT ACTTCACGCT GGCGTTGATC ATCTGGAACT TCGGTGTGGT GGGAATGATC 
TGCATCCACT GGAAGGGGCC GCTGCGGCTC CAGCAGGCCT ATCTGATCAT GATCAGCGCT 
CTCATGGCTC TGGTCTTCAT CAAGTATCTC CCCGAGTGGA CCGCATGGCT CATCCTCGCT 
GCTATTTCAG TCTACGATCT TCTGGCAGTG TTGTGTCCGA AAGGCCCTCT GCGAATCCTT 
GTGGAAACAG CTCAAGAGAG GAATGAGGCC ATTTTCCCAG CGCTCATCTA CTCCTCTACG 
ATGGTGTGGC TCTTCAATAT GGCGGACAGT GCTGAAACCA GGAATAATTC CAGTCATCCA 
GTCCCTCAGC AGGAGAACCA GGTAGTTGCG ATGGCTCCCA CAGCTCAGCC GGAGGACGAT 
GGCGGCTTCA CTCCGGCGTG GGTGGATCAT CAGCAGCATC AGCTCGGACC CATGCAGTCC 
ACGGAGGAGA GCAGACGACA GATCCAGGAG ATGCCCAGCG CTCGGCCACC ACCACCAGCA 
GATGATGACG AAGAGCGGGG TGTGAAGCTG GGTTTGGGAG ATTTCATCTT TTACAGTATG 
CTGGTGGGTA AAGCATCAGC TACAGCCAGC GGTGACTGGA ACACGACGTT AGCCTGCTTC 
GTGGCCATTC TCATTGGTTT ATGTCTGACT CTCCTCCTGC TGGCCATCTT CAAGAAGGCT 
CTTCCCGCAC TCCCCATCTC CATAACCTTC GGCCTGGTGT TTTACTTTGC CACTGATAAC 
CTCGTGCGGC CGTTCATGGA CCAGCTGGCC GTCCATCAGT TCTACATATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005169939.1
CDS	151..1521
Translation	MADLVQNAANNVLNDGMDTSRHTSSTAAPPSRNEVELNGQPPTAPPPQVVTDSEEDEDEELTLKYGAKHVIMLFIPVTLCMVVVVATIKSVSFYTQKDGQQLIYTPFREDTETVGQRALHSMLNAIIMISVIVVMTLVLVVLYKYRCYKVIQAWLFFSNLLLLFFFSLIYLGEVFKTYNVAMDYFTLALIIWNFGVVGMICIHWKGPLRLQQAYLIMISALMALVFIKYLPEWTAWLILAAISVYDLLAVLCPKGPLRILVETAQERNEAIFPALIYSSTMVWLFNMADSAETRNNSSHPVPQQENQVVAMAPTAQPEDDGGFTPAWVDHQQHQLGPMQSTEESRRQIQEMPSARPPPPADDDEERGVKLGLGDFIFYSMLVGKASATASGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFATDNLVRPFMDQLAVHQFYI

Target ORF information:

RefSeq Version	XM_005169882.4
Organism	Danio rerio(zebrafish)
Definition	Danio rerio presenilin 1 (psen1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005169882.4

ORF Insert Sequence:

ATGGCTGATT TAGTGCAGAA TGCTGCCAAT AATGTGCTAA ATGATGGGAT GGACACCAGC 
CGGCACACAA GCAGCACCGC GGCGCCGCCC AGCCGTAATG AGGTGGAGCT GAACGGGCAG 
CCGCCCACCG CTCCGCCCCC GCAGGTGGTC ACAGACAGTG AGGAAGACGA GGACGAGGAG 
CTCACTCTCA AATATGGGGC GAAGCACGTC ATCATGCTGT TCATTCCCGT CACGCTCTGC 
ATGGTGGTGG TGGTGGCGAC CATCAAATCT GTCAGCTTCT ACACACAGAA GGACGGACAG 
CAGCTGATCT ACACCCCGTT TCGTGAGGAC ACGGAGACGG TGGGTCAGCG AGCTCTGCAC 
TCCATGCTCA ACGCCATCAT CATGATCAGT GTGATCGTGG TCATGACCCT GGTGCTGGTG 
GTGCTCTACA AGTACAGATG CTACAAGGTG ATTCAAGCCT GGCTGTTCTT CTCCAACCTC 
CTCCTGCTCT TCTTTTTCTC CTTAATTTAT TTGGGGGAAG TGTTCAAGAC GTATAACGTG 
GCGATGGATT ACTTCACGCT GGCGTTGATC ATCTGGAACT TCGGTGTGGT GGGAATGATC 
TGCATCCACT GGAAGGGGCC GCTGCGGCTC CAGCAGGCCT ATCTGATCAT GATCAGCGCT 
CTCATGGCTC TGGTCTTCAT CAAGTATCTC CCCGAGTGGA CCGCATGGCT CATCCTCGCT 
GCTATTTCAG TCTACGATCT TCTGGCAGTG TTGTGTCCGA AAGGCCCTCT GCGAATCCTT 
GTGGAAACAG CTCAAGAGAG GAATGAGGCC ATTTTCCCAG CGCTCATCTA CTCCTCTACG 
ATGGTGTGGC TCTTCAATAT GGCGGACAGT GCTGAAACCA GGAATAATTC CAGTCATCCA 
GTCCCTCAGC AGGAGAACCA GGTAGTTGCG ATGGCTCCCA CAGCTCAGCC GGAGGACGAT 
GGCGGCTTCA CTCCGGCGTG GGTGGATCAT CAGCAGCATC AGCTCGGACC CATGCAGTCC 
ACGGAGGAGA GCAGACGACA GATCCAGGAG ATGCCCAGCG CTCGGCCACC ACCACCAGCA 
GATGATGACG AAGAGCGGGG TGTGAAGCTG GGTTTGGGAG ATTTCATCTT TTACAGTATG 
CTGGTGGGTA AAGCATCAGC TACAGCCAGC GGTGACTGGA ACACGACGTT AGCCTGCTTC 
GTGGCCATTC TCATTGGTTT ATGTCTGACT CTCCTCCTGC TGGCCATCTT CAAGAAGGCT 
CTTCCCGCAC TCCCCATCTC CATAACCTTC GGCCTGGTGT TTTACTTTGC CACTGATAAC 
CTCGTGCGGC CGTTCATGGA CCAGCTGGCC GTCCATCAGT TCTACATATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

psen1 ( XM_005169883.3 ) cDNA ORF clone, Danio rerio(zebrafish) -> XP_005169940.1 Danio rerio presenilin 1 (psen1), transcript variant X2, mRNA.

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CloneID	ODa22938
Clone ID Related Accession (Same CDS sequence)	XM_005169883.3 , XM_005169883.4
Accession Version	XM_005169883.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1368bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-23
Organism	Danio rerio(Zebrafish)
Product	presenilin-1 isoform X2
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_007128.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 24, 2016 this sequence version replaced XM_005169883.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Danio rerio Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGATT TAGTGCAGAA TGCTGCCAAT AATGTGCTAA ATGATGGGAT GGACACCAGC 
CGGCACACAA GCAGCACCGC GGCGCCGCCC AGCCGTAATG AGGTGGAGCT GAACGGGCAG 
CCGCCCACCG CTCCGCCCCC GCAGGTGGTC ACAGACAGTG AGGAAGACGA GGACGAGGAG 
CTCACTCTCA AATATGGGGC GAAGCACGTC ATCATGCTGT TCATTCCCGT CACGCTCTGC 
ATGGTGGTGG TGGTGGCGAC CATCAAATCT GTCAGCTTCT ACACACAGAA GGACGGACAG 
CAGCTGATCT ACACCCCGTT TCGTGAGGAC ACGGAGACGG TGGGTCAGCG AGCTCTGCAC 
TCCATGCTCA ACGCCATCAT CATGATCAGT GTGATCGTGG TCATGACCCT GGTGCTGGTG 
GTGCTCTACA AGTACAGATG CTACAAGGTG ATTCAAGCCT GGCTGTTCTT CTCCAACCTC 
CTCCTGCTCT TCTTTTTCTC CTTAATTTAT TTGGGGGAAG TGTTCAAGAC GTATAACGTG 
GCGATGGATT ACTTCACGCT GGCGTTGATC ATCTGGAACT TCGGTGTGGT GGGAATGATC 
TGCATCCACT GGAAGGGGCC GCTGCGGCTC CAGCAGGCCT ATCTGATCAT GATCAGCGCT 
CTCATGGCTC TGGTCTTCAT CAAGTATCTC CCCGAGTGGA CCGCATGGCT CATCCTCGCT 
GCTATTTCAG TCTACGATCT TCTGGCAGTG TTGTGTCCGA AAGGCCCTCT GCGAATCCTT 
GTGGAAACAG CTCAAGAGAG GAATGAGGCC ATTTTCCCAG CGCTCATCTA CTCCTCTACG 
ATGGTGTGGC TCTTCAATAT GGCGGACAGT GCTGAAACCA GGAATAATTC CAGTCATCCA 
GTCCCTCAGC AGGAGAACCA GGTTGCGATG GCTCCCACAG CTCAGCCGGA GGACGATGGC 
GGCTTCACTC CGGCGTGGGT GGATCATCAG CAGCATCAGC TCGGACCCAT GCAGTCCACG 
GAGGAGAGCA GACGACAGAT CCAGGAGATG CCCAGCGCTC GGCCACCACC ACCAGCAGAT 
GATGACGAAG AGCGGGGTGT GAAGCTGGGT TTGGGAGATT TCATCTTTTA CAGTATGCTG 
GTGGGTAAAG CATCAGCTAC AGCCAGCGGT GACTGGAACA CGACGTTAGC CTGCTTCGTG 
GCCATTCTCA TTGGTTTATG TCTGACTCTC CTCCTGCTGG CCATCTTCAA GAAGGCTCTT 
CCCGCACTCC CCATCTCCAT AACCTTCGGC CTGGTGTTTT ACTTTGCCAC TGATAACCTC 
GTGCGGCCGT TCATGGACCA GCTGGCCGTC CATCAGTTCT ACATATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005169940.1
CDS	130..1497
Translation	MADLVQNAANNVLNDGMDTSRHTSSTAAPPSRNEVELNGQPPTAPPPQVVTDSEEDEDEELTLKYGAKHVIMLFIPVTLCMVVVVATIKSVSFYTQKDGQQLIYTPFREDTETVGQRALHSMLNAIIMISVIVVMTLVLVVLYKYRCYKVIQAWLFFSNLLLLFFFSLIYLGEVFKTYNVAMDYFTLALIIWNFGVVGMICIHWKGPLRLQQAYLIMISALMALVFIKYLPEWTAWLILAAISVYDLLAVLCPKGPLRILVETAQERNEAIFPALIYSSTMVWLFNMADSAETRNNSSHPVPQQENQVAMAPTAQPEDDGGFTPAWVDHQQHQLGPMQSTEESRRQIQEMPSARPPPPADDDEERGVKLGLGDFIFYSMLVGKASATASGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFATDNLVRPFMDQLAVHQFYI

Target ORF information:

RefSeq Version	XM_005169883.3
Organism	Danio rerio(Zebrafish)
Definition	Danio rerio presenilin 1 (psen1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005169883.3

ORF Insert Sequence:

ATGGCTGATT TAGTGCAGAA TGCTGCCAAT AATGTGCTAA ATGATGGGAT GGACACCAGC 
CGGCACACAA GCAGCACCGC GGCGCCGCCC AGCCGTAATG AGGTGGAGCT GAACGGGCAG 
CCGCCCACCG CTCCGCCCCC GCAGGTGGTC ACAGACAGTG AGGAAGACGA GGACGAGGAG 
CTCACTCTCA AATATGGGGC GAAGCACGTC ATCATGCTGT TCATTCCCGT CACGCTCTGC 
ATGGTGGTGG TGGTGGCGAC CATCAAATCT GTCAGCTTCT ACACACAGAA GGACGGACAG 
CAGCTGATCT ACACCCCGTT TCGTGAGGAC ACGGAGACGG TGGGTCAGCG AGCTCTGCAC 
TCCATGCTCA ACGCCATCAT CATGATCAGT GTGATCGTGG TCATGACCCT GGTGCTGGTG 
GTGCTCTACA AGTACAGATG CTACAAGGTG ATTCAAGCCT GGCTGTTCTT CTCCAACCTC 
CTCCTGCTCT TCTTTTTCTC CTTAATTTAT TTGGGGGAAG TGTTCAAGAC GTATAACGTG 
GCGATGGATT ACTTCACGCT GGCGTTGATC ATCTGGAACT TCGGTGTGGT GGGAATGATC 
TGCATCCACT GGAAGGGGCC GCTGCGGCTC CAGCAGGCCT ATCTGATCAT GATCAGCGCT 
CTCATGGCTC TGGTCTTCAT CAAGTATCTC CCCGAGTGGA CCGCATGGCT CATCCTCGCT 
GCTATTTCAG TCTACGATCT TCTGGCAGTG TTGTGTCCGA AAGGCCCTCT GCGAATCCTT 
GTGGAAACAG CTCAAGAGAG GAATGAGGCC ATTTTCCCAG CGCTCATCTA CTCCTCTACG 
ATGGTGTGGC TCTTCAATAT GGCGGACAGT GCTGAAACCA GGAATAATTC CAGTCATCCA 
GTCCCTCAGC AGGAGAACCA GGTTGCGATG GCTCCCACAG CTCAGCCGGA GGACGATGGC 
GGCTTCACTC CGGCGTGGGT GGATCATCAG CAGCATCAGC TCGGACCCAT GCAGTCCACG 
GAGGAGAGCA GACGACAGAT CCAGGAGATG CCCAGCGCTC GGCCACCACC ACCAGCAGAT 
GATGACGAAG AGCGGGGTGT GAAGCTGGGT TTGGGAGATT TCATCTTTTA CAGTATGCTG 
GTGGGTAAAG CATCAGCTAC AGCCAGCGGT GACTGGAACA CGACGTTAGC CTGCTTCGTG 
GCCATTCTCA TTGGTTTATG TCTGACTCTC CTCCTGCTGG CCATCTTCAA GAAGGCTCTT 
CCCGCACTCC CCATCTCCAT AACCTTCGGC CTGGTGTTTT ACTTTGCCAC TGATAACCTC 
GTGCGGCCGT TCATGGACCA GCTGGCCGTC CATCAGTTCT ACATATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

psen1 ( XM_005169883.4 ) cDNA ORF clone, Danio rerio(zebrafish) -> XP_005169940.1 Danio rerio presenilin 1 (psen1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ODa22938
Clone ID Related Accession (Same CDS sequence)	XM_005169883.3 , XM_005169883.4
Accession Version	XM_005169883.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1368bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-06-14
Organism	Danio rerio(zebrafish)
Product	presenilin-1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_007128.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 15, 2017 this sequence version replaced XM_005169883.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Danio rerio Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGATT TAGTGCAGAA TGCTGCCAAT AATGTGCTAA ATGATGGGAT GGACACCAGC 
CGGCACACAA GCAGCACCGC GGCGCCGCCC AGCCGTAATG AGGTGGAGCT GAACGGGCAG 
CCGCCCACCG CTCCGCCCCC GCAGGTGGTC ACAGACAGTG AGGAAGACGA GGACGAGGAG 
CTCACTCTCA AATATGGGGC GAAGCACGTC ATCATGCTGT TCATTCCCGT CACGCTCTGC 
ATGGTGGTGG TGGTGGCGAC CATCAAATCT GTCAGCTTCT ACACACAGAA GGACGGACAG 
CAGCTGATCT ACACCCCGTT TCGTGAGGAC ACGGAGACGG TGGGTCAGCG AGCTCTGCAC 
TCCATGCTCA ACGCCATCAT CATGATCAGT GTGATCGTGG TCATGACCCT GGTGCTGGTG 
GTGCTCTACA AGTACAGATG CTACAAGGTG ATTCAAGCCT GGCTGTTCTT CTCCAACCTC 
CTCCTGCTCT TCTTTTTCTC CTTAATTTAT TTGGGGGAAG TGTTCAAGAC GTATAACGTG 
GCGATGGATT ACTTCACGCT GGCGTTGATC ATCTGGAACT TCGGTGTGGT GGGAATGATC 
TGCATCCACT GGAAGGGGCC GCTGCGGCTC CAGCAGGCCT ATCTGATCAT GATCAGCGCT 
CTCATGGCTC TGGTCTTCAT CAAGTATCTC CCCGAGTGGA CCGCATGGCT CATCCTCGCT 
GCTATTTCAG TCTACGATCT TCTGGCAGTG TTGTGTCCGA AAGGCCCTCT GCGAATCCTT 
GTGGAAACAG CTCAAGAGAG GAATGAGGCC ATTTTCCCAG CGCTCATCTA CTCCTCTACG 
ATGGTGTGGC TCTTCAATAT GGCGGACAGT GCTGAAACCA GGAATAATTC CAGTCATCCA 
GTCCCTCAGC AGGAGAACCA GGTTGCGATG GCTCCCACAG CTCAGCCGGA GGACGATGGC 
GGCTTCACTC CGGCGTGGGT GGATCATCAG CAGCATCAGC TCGGACCCAT GCAGTCCACG 
GAGGAGAGCA GACGACAGAT CCAGGAGATG CCCAGCGCTC GGCCACCACC ACCAGCAGAT 
GATGACGAAG AGCGGGGTGT GAAGCTGGGT TTGGGAGATT TCATCTTTTA CAGTATGCTG 
GTGGGTAAAG CATCAGCTAC AGCCAGCGGT GACTGGAACA CGACGTTAGC CTGCTTCGTG 
GCCATTCTCA TTGGTTTATG TCTGACTCTC CTCCTGCTGG CCATCTTCAA GAAGGCTCTT 
CCCGCACTCC CCATCTCCAT AACCTTCGGC CTGGTGTTTT ACTTTGCCAC TGATAACCTC 
GTGCGGCCGT TCATGGACCA GCTGGCCGTC CATCAGTTCT ACATATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005169940.1
CDS	152..1519
Translation	MADLVQNAANNVLNDGMDTSRHTSSTAAPPSRNEVELNGQPPTAPPPQVVTDSEEDEDEELTLKYGAKHVIMLFIPVTLCMVVVVATIKSVSFYTQKDGQQLIYTPFREDTETVGQRALHSMLNAIIMISVIVVMTLVLVVLYKYRCYKVIQAWLFFSNLLLLFFFSLIYLGEVFKTYNVAMDYFTLALIIWNFGVVGMICIHWKGPLRLQQAYLIMISALMALVFIKYLPEWTAWLILAAISVYDLLAVLCPKGPLRILVETAQERNEAIFPALIYSSTMVWLFNMADSAETRNNSSHPVPQQENQVAMAPTAQPEDDGGFTPAWVDHQQHQLGPMQSTEESRRQIQEMPSARPPPPADDDEERGVKLGLGDFIFYSMLVGKASATASGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFATDNLVRPFMDQLAVHQFYI

Target ORF information:

RefSeq Version	XM_005169883.4
Organism	Danio rerio(zebrafish)
Definition	Danio rerio presenilin 1 (psen1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005169883.4

ORF Insert Sequence:

ATGGCTGATT TAGTGCAGAA TGCTGCCAAT AATGTGCTAA ATGATGGGAT GGACACCAGC 
CGGCACACAA GCAGCACCGC GGCGCCGCCC AGCCGTAATG AGGTGGAGCT GAACGGGCAG 
CCGCCCACCG CTCCGCCCCC GCAGGTGGTC ACAGACAGTG AGGAAGACGA GGACGAGGAG 
CTCACTCTCA AATATGGGGC GAAGCACGTC ATCATGCTGT TCATTCCCGT CACGCTCTGC 
ATGGTGGTGG TGGTGGCGAC CATCAAATCT GTCAGCTTCT ACACACAGAA GGACGGACAG 
CAGCTGATCT ACACCCCGTT TCGTGAGGAC ACGGAGACGG TGGGTCAGCG AGCTCTGCAC 
TCCATGCTCA ACGCCATCAT CATGATCAGT GTGATCGTGG TCATGACCCT GGTGCTGGTG 
GTGCTCTACA AGTACAGATG CTACAAGGTG ATTCAAGCCT GGCTGTTCTT CTCCAACCTC 
CTCCTGCTCT TCTTTTTCTC CTTAATTTAT TTGGGGGAAG TGTTCAAGAC GTATAACGTG 
GCGATGGATT ACTTCACGCT GGCGTTGATC ATCTGGAACT TCGGTGTGGT GGGAATGATC 
TGCATCCACT GGAAGGGGCC GCTGCGGCTC CAGCAGGCCT ATCTGATCAT GATCAGCGCT 
CTCATGGCTC TGGTCTTCAT CAAGTATCTC CCCGAGTGGA CCGCATGGCT CATCCTCGCT 
GCTATTTCAG TCTACGATCT TCTGGCAGTG TTGTGTCCGA AAGGCCCTCT GCGAATCCTT 
GTGGAAACAG CTCAAGAGAG GAATGAGGCC ATTTTCCCAG CGCTCATCTA CTCCTCTACG 
ATGGTGTGGC TCTTCAATAT GGCGGACAGT GCTGAAACCA GGAATAATTC CAGTCATCCA 
GTCCCTCAGC AGGAGAACCA GGTTGCGATG GCTCCCACAG CTCAGCCGGA GGACGATGGC 
GGCTTCACTC CGGCGTGGGT GGATCATCAG CAGCATCAGC TCGGACCCAT GCAGTCCACG 
GAGGAGAGCA GACGACAGAT CCAGGAGATG CCCAGCGCTC GGCCACCACC ACCAGCAGAT 
GATGACGAAG AGCGGGGTGT GAAGCTGGGT TTGGGAGATT TCATCTTTTA CAGTATGCTG 
GTGGGTAAAG CATCAGCTAC AGCCAGCGGT GACTGGAACA CGACGTTAGC CTGCTTCGTG 
GCCATTCTCA TTGGTTTATG TCTGACTCTC CTCCTGCTGG CCATCTTCAA GAAGGCTCTT 
CCCGCACTCC CCATCTCCAT AACCTTCGGC CTGGTGTTTT ACTTTGCCAC TGATAACCTC 
GTGCGGCCGT TCATGGACCA GCTGGCCGTC CATCAGTTCT ACATATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Mitochondrion to endoplasmic reticulum apposition length in zebrafish embryo spinal progenitors is unchanged in response to perturbations associated with Alzheimer's disease.
PloS one12(6)e0179859(2017)
Newman M,Halter L,Lim A,Lardelli M

Transcriptomic profiling of mTOR and ryanodine receptor signaling molecules in developing zebrafish in the absence and presence of PCB 95.
PeerJ5e4106(2017)
Frank DF,Miller GW,Connon RE,Geist J,Lein PJ

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psen1 cDNA ORF clone, Danio rerio(zebrafish)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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