sec61a1l cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	sec61a1l
Entrez Gene ID	266796
Full Name	Sec61 translocon alpha 1 subunit, like
Synonyms	cb413,sec61al2,sec61b,wu:fb36f05,wu:fb36f12,wu:fb37d04,wu:fi26f11
General protein information	Preferred Names Sec61 translocon alpha 1 subunit, like Names protein transport protein Sec61 subunit alpha-like 2 SEC61, beta subunit Sec61 alpha like 2 transport protein Sec61 subunit alpha like 2
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_201577.1	NP_963871.1	protein transport protein Sec61 subunit alpha-like 2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	SEC61A1	XP_003310030.1
Danio rerio (zebrafish)	sec61a1	NP_705945.1
Danio rerio (zebrafish)	sec61al2	NP_963871.1
Kluyveromyces lactis	KLLA0E01145g	XP_454000.1
Bos taurus (cattle)	SEC61A1	NP_001035594.1
Gallus gallus (chicken)	SEC61A1	XP_414364.3
Saccharomyces cerevisiae (baker's yeast)	SEC61	NP_013482.1
Eremothecium gossypii	AGOS_AFR596W	NP_986143.1
Oryza sativa (rice)	Os09g0347700	NP_001062945.1
Homo sapiens (human)	SEC61A1	NP_037468.1
Rattus norvegicus (Norway rat)	Sec61a1	NP_954865.1
Schizosaccharomyces pombe (fission yeast)	sec61	NP_595226.1
Arabidopsis thaliana (thale cress)	AT1G29310	NP_174225.2
Xenopus tropicalis (tropical clawed frog)	sec61a1	NP_001004801.1
Canis lupus familiaris (dog)	SEC61A1	NP_001003315.1
Mus musculus (house mouse)	Sec61a1	NP_058602.1
Neurospora crassa	NCU08897	XP_958835.1
Arabidopsis thaliana (thale cress)	AT2G34250	NP_180972.1
Oryza sativa (rice)	Os03g0213100	NP_001049359.1
	SEC61A1	XP_002798757.1
Magnaporthe oryzae (rice blast fungus)	MGG_04856	XP_003712335.1

Gene Ontology
Bibliography

Related articles in PubMed

Evolution of complexity in the zebrafish synapse proteome.
Bay?s ?, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG
Nature communications814613(2017 Mar)

Heterozygous Loss-of-Function SEC61A1 Mutations Cause Autosomal-Dominant Tubulo-Interstitial and Glomerulocystic Kidney Disease with Anemia.
Bolar NA, Golzio C, ?ivn? M, Hayot G, Van Hemelrijk C, Schepers D, Vandeweyer G, Hoischen A, Huyghe JR, Raes A, Matthys E, Sys E, Azou M, Gubler MC, Praet M, Van Camp G, McFadden K, Pediaditakis I, P?istoupilov? A, Hoda?ov? K, Vyle?al P, Hartmannov? H, Str?neck? V, H?lkov? H, Bare?ov? V, Jedli?kov? I, Sovov? J, Hn?zda A, Kidd K, Bleyer AJ, Spong RS, Vande Walle J, Mortier G, Brunner H, Van Laer L, Kmoch S, Katsanis N, Loeys BL
American journal of human genetics99(1)174-87(2016 Jul)

Protein palmitoylation activate zygotic gene expression during the maternal-to-zygotic transition.
Du Z, Chen X, Li X, He K, Ji S, Shi W, Hao A
Biochemical and biophysical research communications475(2)194-201(2016 06)

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y, Bobe J
BMC genomics17368(2016 05)

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following sec61a1l gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the sec61a1l cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa37436	NM_201577.1 Latest version!	Danio rerio SEC61 translocon subunit alpha 1, like (sec61a1l), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

sec61a1l ( NM_201577.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_963871.1 Danio rerio SEC61 translocon subunit alpha 1, like (sec61a1l), mRNA.

Price & Availability↑

CloneID	ODa37436
Clone ID Related Accession (Same CDS sequence)	NM_201577.1
Accession Version	NM_201577.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1431bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-08
Organism	Danio rerio(zebrafish)
Product	protein transport protein Sec61 subunit alpha-like 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY034614.1. ##Evidence-Data-START## Transcript exon combination :: AY034614.1, BC048881.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2168446, SAMEA2168447 [ECO:0000350] ##Evidence-Data-END##

ATGGCCATTA AATTCTTGGA AGTAATAAAA CCATTCTGTG CGGTTTTACC CGAGATCCAG 
AAGCCTGAGA GGAGGATTCA GTTCAAAGAA AAGGTGTTAT GGACTGCGAT CACTCTTTTC 
ATCTTTCTGG TTTGCTGCCA GATTCCTCTT TTTGGAATCA TGTCTTCGGA CTCAGCAGAT 
CCCTTTTATT GGATGAGAGT GATCATGGCA TCCAACAGAG GTACTTTGAT GGAGTTGGGT 
ATCTCTCCCA TTGTGACGTC TGGCCTGATC ATGCAGCTGT TGGCTGGAGC TAAGATCATT 
GAGGTTGGAG ACACCCCTAA AGACAGAGCG CTCTTTAATG GGGCTCAGAA ACTGTTTGGC 
ATGATCATCA CCATTGGTCA GGCTATCGTT TATGTGATGA CTGGTATGTA TGGAGATCCT 
TCAGAGATGG GTGCTGGAAT CTGCCTTCTC ATTATCATCC AGTTGTTTGT AGCCGGTCTG 
ATCGTGTTGC TGCTGGATGA GTTACTCCAA AAGGGCTATG GATTGGGCTC TGGTATCTCT 
CTCTTCATCG CCACCAACAT CTGTGAGACA ATCGTATGGA AGGCATTCAG CCCAACAACA 
GTCAACACAG GAAGAGGCAC GGAGTTTGAA GGAGCCATCA TTGCTCTCTT TCACCTATTG 
GCCACTCGTA CTGATAAAGT GCGAGCTCTA AGAGAAGCCT TTTACAGACA GAACCTGCCC 
AACCTCATGA ACCTCATCGC TACAATCTTC GTCTTTGCTG TGGTCATATA CTTCCAGGGA 
TTTAGAGTCG ATCTGCCCAT CAAATCTGCA CGTTACCGTG GCCAGTACAA CACCTATCCC 
ATCAAGCTCT TCTACACCTC CAACATTCCC ATCATCCTGC AGTCTGCACT GGTGTCCAAT 
CTTTACGTCA TCTCTCAAAT GCTCTCAACT CGCTTCAGTG GAAACTTCCT GGTCAACCTT 
TTGGGGACTT GGTCGGATAC CTCAACTGGA GGACCGGCTC GTGCTTACCC AGTAGGTGGC 
CTTTGCTACT ACCTCTCACC CCCAGAGTCC TTTGGCACAG TTCTGGAGGA TCCAATCCAT 
GCCATCATCT ACATCATCTT CATGCTGGGA TCGTGTGCCT TCTTCTCAAA GACCTGGATT 
GAAGTTTCCG GATCATCTGC CAAAGATGTT GCCAAACAGC TTAAAGAACA GCAGATGGTA 
ATGAGAGGAC ACAGAGAAAC ATCAATGGTC CATGAACTGA ACAGGTACAT CCCTACAGCG 
GCAGCCTTCG GAGGCCTGTG TATAGGCGGT CTCTCAGTCA TGGCTGACTT TCTGGGAGCC 
ATCGGATCAG GAACTGGAAT TTTGTTGGCC GTCACTATCA TCTACCAGTA CTTTGAGATC 
TTTGTGAAGG AACAGAGCGA AGTGGGCAGT GTGGGAGCTC TCCTGTTCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_963871.1
CDS	69..1499
Translation	MAIKFLEVIKPFCAVLPEIQKPERRIQFKEKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWMRVIMASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFGMIITIGQAIVYVMTGMYGDPSEMGAGICLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPTTVNTGRGTEFEGAIIALFHLLATRTDKVRALREAFYRQNLPNLMNLIATIFVFAVVIYFQGFRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSTRFSGNFLVNLLGTWSDTSTGGPARAYPVGGLCYYLSPPESFGTVLEDPIHAIIYIIFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGGLSVMADFLGAIGSGTGILLAVTIIYQYFEIFVKEQSEVGSVGALLF

Target ORF information:

RefSeq Version	NM_201577.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio SEC61 translocon subunit alpha 1, like (sec61a1l), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_201577.1

ORF Insert Sequence:

ATGGCCATTA AATTCTTGGA AGTAATAAAA CCATTCTGTG CGGTTTTACC CGAGATCCAG 
AAGCCTGAGA GGAGGATTCA GTTCAAAGAA AAGGTGTTAT GGACTGCGAT CACTCTTTTC 
ATCTTTCTGG TTTGCTGCCA GATTCCTCTT TTTGGAATCA TGTCTTCGGA CTCAGCAGAT 
CCCTTTTATT GGATGAGAGT GATCATGGCA TCCAACAGAG GTACTTTGAT GGAGTTGGGT 
ATCTCTCCCA TTGTGACGTC TGGCCTGATC ATGCAGCTGT TGGCTGGAGC TAAGATCATT 
GAGGTTGGAG ACACCCCTAA AGACAGAGCG CTCTTTAATG GGGCTCAGAA ACTGTTTGGC 
ATGATCATCA CCATTGGTCA GGCTATCGTT TATGTGATGA CTGGTATGTA TGGAGATCCT 
TCAGAGATGG GTGCTGGAAT CTGCCTTCTC ATTATCATCC AGTTGTTTGT AGCCGGTCTG 
ATCGTGTTGC TGCTGGATGA GTTACTCCAA AAGGGCTATG GATTGGGCTC TGGTATCTCT 
CTCTTCATCG CCACCAACAT CTGTGAGACA ATCGTATGGA AGGCATTCAG CCCAACAACA 
GTCAACACAG GAAGAGGCAC GGAGTTTGAA GGAGCCATCA TTGCTCTCTT TCACCTATTG 
GCCACTCGTA CTGATAAAGT GCGAGCTCTA AGAGAAGCCT TTTACAGACA GAACCTGCCC 
AACCTCATGA ACCTCATCGC TACAATCTTC GTCTTTGCTG TGGTCATATA CTTCCAGGGA 
TTTAGAGTCG ATCTGCCCAT CAAATCTGCA CGTTACCGTG GCCAGTACAA CACCTATCCC 
ATCAAGCTCT TCTACACCTC CAACATTCCC ATCATCCTGC AGTCTGCACT GGTGTCCAAT 
CTTTACGTCA TCTCTCAAAT GCTCTCAACT CGCTTCAGTG GAAACTTCCT GGTCAACCTT 
TTGGGGACTT GGTCGGATAC CTCAACTGGA GGACCGGCTC GTGCTTACCC AGTAGGTGGC 
CTTTGCTACT ACCTCTCACC CCCAGAGTCC TTTGGCACAG TTCTGGAGGA TCCAATCCAT 
GCCATCATCT ACATCATCTT CATGCTGGGA TCGTGTGCCT TCTTCTCAAA GACCTGGATT 
GAAGTTTCCG GATCATCTGC CAAAGATGTT GCCAAACAGC TTAAAGAACA GCAGATGGTA 
ATGAGAGGAC ACAGAGAAAC ATCAATGGTC CATGAACTGA ACAGGTACAT CCCTACAGCG 
GCAGCCTTCG GAGGCCTGTG TATAGGCGGT CTCTCAGTCA TGGCTGACTT TCTGGGAGCC 
ATCGGATCAG GAACTGGAAT TTTGTTGGCC GTCACTATCA TCTACCAGTA CTTTGAGATC 
TTTGTGAAGG AACAGAGCGA AGTGGGCAGT GTGGGAGCTC TCCTGTTCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Evolution of complexity in the zebrafish synapse proteome.
Nature communications814613(2017 Mar)
Bay?s ?,Collins MO,Reig-Viader R,Gou G,Goulding D,Izquierdo A,Choudhary JS,Emes RD,Grant SG

Heterozygous Loss-of-Function SEC61A1 Mutations Cause Autosomal-Dominant Tubulo-Interstitial and Glomerulocystic Kidney Disease with Anemia.
American journal of human genetics99(1)174-87(2016 Jul)
Bolar NA,Golzio C,?ivn? M,Hayot G,Van Hemelrijk C,Schepers D,Vandeweyer G,Hoischen A,Huyghe JR,Raes A,Matthys E,Sys E,Azou M,Gubler MC,Praet M,Van Camp G,McFadden K,Pediaditakis I,P?istoupilov? A,Hoda?ov? K,Vyle?al P,Hartmannov? H,Str?neck? V,H?lkov? H,Bare?ov? V,Jedli?kov? I,Sovov? J,Hn?zda A,Kidd K,Bleyer AJ,Spong RS,Vande Walle J,Mortier G,Brunner H,Van Laer L,Kmoch S,Katsanis N,Loeys BL

Protein palmitoylation activate zygotic gene expression during the maternal-to-zygotic transition.
Biochemical and biophysical research communications475(2)194-201(2016 06)
Du Z,Chen X,Li X,He K,Ji S,Shi W,Hao A

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
BMC genomics17368(2016 05)
Pasquier J,Cabau C,Nguyen T,Jouanno E,Severac D,Braasch I,Journot L,Pontarotti P,Klopp C,Postlethwait JH,Guiguen Y,Bobe J

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

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sec61a1l cDNA ORF clone, Danio rerio(zebrafish)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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