elmo2 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	elmo2
Entrez Gene ID	100006857
Full Name	engulfment and cell motility 2
General protein information	Preferred Names engulfment and cell motility 2 Names engulfment and cell motility protein 2 zmp:0000001124
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001200058.1	NP_001186987.1	engulfment and cell motility protein 2

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	ELMO2	XP_005635189.1
Danio rerio (zebrafish)	LOC100006857	NP_001186987.1
Xenopus tropicalis (tropical clawed frog)	elmo1	NP_001008123.1
Mus musculus (house mouse)	Elmo2	NP_997589.1
Bos taurus (cattle)	ELMO2	NP_001076860.1
Magnaporthe oryzae (rice blast fungus)	MGG_09944	XP_003710048.1
Pan troglodytes (chimpanzee)	ELMO2	XP_514693.2
	ELMO2	XP_002798158.1
Rattus norvegicus (Norway rat)	Elmo2	NP_001128427.1
Gallus gallus (chicken)	ELMO2	XP_004947265.1
Homo sapiens (human)	ELMO2	NP_877496.1
Neurospora crassa	NCU03264	XP_964417.1

Gene Ontology
Bibliography

Related articles in PubMed

Evolution of complexity in the zebrafish synapse proteome.
Bay?s ?, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG
Nature communications814613(2017 Mar)

Loss-of-Function Mutations in ELMO2 Cause Intraosseous Vascular Malformation by Impeding RAC1 Signaling.
Cetinkaya A, Xiong JR, Vargel ?, K?semehmeto?lu K, Canter H?, Gerdan ?F, Longo N, Alzahrani A, Camps MP, Taskiran EZ, Laupheimer S, Botto LD, Paramalingam E, Gormez Z, Uz E, Yuksel B, Ruacan ?, Sa??ro?lu M?, Takahashi T, Reversade B, Akarsu NA
American journal of human genetics99(2)299-317(2016 Aug)

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following elmo2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the elmo2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa04046	NM_001200058.1 Latest version!	Danio rerio engulfment and cell motility 2 (elmo2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$426.30 $609.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

elmo2 ( NM_001200058.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001186987.1 Danio rerio engulfment and cell motility 2 (elmo2), mRNA.

Price & Availability↑

CloneID	ODa04046
Clone ID Related Accession (Same CDS sequence)	NM_001200058.1
Accession Version	NM_001200058.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2136bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-01-26
Organism	Danio rerio(zebrafish)
Product	engulfment and cell motility protein 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from LO017730.1, CABZ01085323.1 and BC125967.1. On Jan 14, 2011 this sequence version replaced XR_082622.2. ##Evidence-Data-START## Transcript exon combination :: GDQH01022879.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2168446, SAMEA2168447 [ECO:0000350] ##Evidence-Data-END##

ATGCCTCCTC CATCAGACAT TGTGAAGGTG GCCATTGAGT GGCCGGGAGC CAACGCTCAG 
CTCATCGAGA TCGACCAGAA GAAGCCTCTG GCCTCCATCA TTCGAGAAGT GTGTGAGGGA 
TGGTCTCTGT CTGGATCGGA GCAGTTCGCT CTCCGCTATG CTGACGGGCC GCAGCTCTAC 
ATCACTGAAC AGACTCGCGG TGAGATTAAG AACGGCACGA TCCTCCGTCT GGCCATCTCT 
CCGATGCGTG CGGCCCGTCA GCTGCTGGAG CGTATCCAGT CTCACAGTAT TGATGCACGT 
TTGGAGGCGC TGAAGGAACT GGCCAAACTC TCAGCCGACG CCGCCTTCGC CAGCGAGTTC 
ATCAACATCG ACGGACTGGT GACGCTGGCA CGACTGGTGG AGAGCGGCAC TCATTTCGGG 
GAGATGCTGG CCTTCACTCT GACGGCGTTT CTGGAGCTGA TGGATCATGG GATTGTGTCG 
TGGGAGCTGC TCTCACTGTC CTTCATCAAA CAGATTGCAG GTTACGTGAA CCAGCCGATG 
GTAGACGTGT CGATCCTGCA GCGCTCGCTG GCCATCCTGG AGAGTATGGT GTTGAACAGC 
CACAGCCTGT ACCAGCGGGT GGCGCAGGAG ACCACAGTCG CACAACTCAT CACACACCTG 
TCCAACCAGG AGATCCAGAC GTACGCCATC GCCCTCATCA ACGCCCTGTT CCTCAAAACC 
CCGGAGGACC GACGCCAGGA GATGGCGGCG ACGCTGGCTC AGAGACACCT GCGCGCCATC 
ATCCTCAATC ACATCATCCG GGGGAACCGG CCCGTGAAGG CGGAGATGGC GCATCAGCTG 
TACGTGCTGC AGGTGCTGAC CTTTAACCTT CTGGAGGAGC GCATGATGAC CAAGATGGAC 
CCCAATGACC AGACTCAGAG AGATGTGATC TTCGAGCTGC GCAGGATTGC GTTTGATGGA 
GACGCAGCAG AACCCAGCGG AACCGAGAAG AGGAAAGCGG CGGCCCACAC CAAAGACTAC 
AGGATGCTGG GATTCAGCAA TGCAGTGAAT CCTGCGCTGG ACTTCACCCA GACGCCGCCG 
GGGATGCTGG CGCTGGACAA CATGCTGTAC CTGGCCAAAC TACACCAGGA CACATACATC 
AGGATTGTTC TGGAAAACAG CAGTCGTGAG GATAAGCACG AGTGTCCGTT CGCGCGCTGT 
GCTATCGAGC TGACGCGGGT GCTGTGTGAT ATTCTGCAGG TCGGAGAGCT GCCGAATGAA 
GGCTGTAATG ACTTCCACCC CATGTTCTTC ACACACGAGC GCGCCTGGGA AGAGTTCTTC 
TGCGTCTGCA TACAGCTGCT CAACAAGACA TGGAAGGAGA TGAGGGCCAC TGCTGAAGAC 
TTCAACAAGG TGATGACGGT GGTGCGTGAG CAGATCACCC GGGCTCTGGC CCTGAAGCCT 
GCGTCTCTGG ATCAGCTGCG GCTGAAGCTG CGCTCTCTGA GTTACTCTGA GATTCTGCGA 
CTGCGTCAGT CCGAGAGAAT GAGCCAAGAT GACTTCCAGT CGCCGCCCAT CATTGAGCTG 
CGGGAGCGGA TCCAGCCGGA GATCCTGGAG CTCATCAAGC AGCAGAGGCT CAGTCGGCTC 
TGTGAGGGAA GCTGCTTCCG CAAACTGGGG AACCGACGCC GGCAGGAGAA GTTCTGGTTC 
TGCCGGCTCT CACTGAACCA CAAGCTGCTC CATTATGGGG ATCTGGAGGA GTCTCCACAG 
GGTGAGGTGC CACTGGAGCT GCTGACCGAC AAGATCGCCG TGTCCGACAT TAAAGCTGTG 
CTGACGGGGA AAGACTGTCC GCATATGAAG GAGAAGAGCG CGCTCAAGCA GAACAAGGAA 
GTGTTGGAGC TGGCGTTCTC CATCCTCTAC GACCCTGACG AGTCCCTCAA CTTCGTGGCA 
CCAAACAAAT ATGAGTACTG TATCTGGACA GACGGCCTGT CAGCTCTGCT AGGGAAGGAT 
CTGTCCAGTG ACCTCACACG AAGTGACCTT GACACACTAA TGAGTATGGA GATGAAGCTC 
CGCCTCCTGG ACCTGGAGAA CATCACCATC CCTGAGGCTC CGCCCCCCGT GCCCAAAGAG 
CCCAGCAGCT ACAACTTCAG CTACAACTAC GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001186987.1
CDS	225..2360
Translation	MPPPSDIVKVAIEWPGANAQLIEIDQKKPLASIIREVCEGWSLSGSEQFALRYADGPQLYITEQTRGEIKNGTILRLAISPMRAARQLLERIQSHSIDARLEALKELAKLSADAAFASEFINIDGLVTLARLVESGTHFGEMLAFTLTAFLELMDHGIVSWELLSLSFIKQIAGYVNQPMVDVSILQRSLAILESMVLNSHSLYQRVAQETTVAQLITHLSNQEIQTYAIALINALFLKTPEDRRQEMAATLAQRHLRAIILNHIIRGNRPVKAEMAHQLYVLQVLTFNLLEERMMTKMDPNDQTQRDVIFELRRIAFDGDAAEPSGTEKRKAAAHTKDYRMLGFSNAVNPALDFTQTPPGMLALDNMLYLAKLHQDTYIRIVLENSSREDKHECPFARCAIELTRVLCDILQVGELPNEGCNDFHPMFFTHERAWEEFFCVCIQLLNKTWKEMRATAEDFNKVMTVVREQITRALALKPASLDQLRLKLRSLSYSEILRLRQSERMSQDDFQSPPIIELRERIQPEILELIKQQRLSRLCEGSCFRKLGNRRRQEKFWFCRLSLNHKLLHYGDLEESPQGEVPLELLTDKIAVSDIKAVLTGKDCPHMKEKSALKQNKEVLELAFSILYDPDESLNFVAPNKYEYCIWTDGLSALLGKDLSSDLTRSDLDTLMSMEMKLRLLDLENITIPEAPPPVPKEPSSYNFSYNYG

Target ORF information:

RefSeq Version	NM_001200058.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio engulfment and cell motility 2 (elmo2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001200058.1

ORF Insert Sequence:

ATGCCTCCTC CATCAGACAT TGTGAAGGTG GCCATTGAGT GGCCGGGAGC CAACGCTCAG 
CTCATCGAGA TCGACCAGAA GAAGCCTCTG GCCTCCATCA TTCGAGAAGT GTGTGAGGGA 
TGGTCTCTGT CTGGATCGGA GCAGTTCGCT CTCCGCTATG CTGACGGGCC GCAGCTCTAC 
ATCACTGAAC AGACTCGCGG TGAGATTAAG AACGGCACGA TCCTCCGTCT GGCCATCTCT 
CCGATGCGTG CGGCCCGTCA GCTGCTGGAG CGTATCCAGT CTCACAGTAT TGATGCACGT 
TTGGAGGCGC TGAAGGAACT GGCCAAACTC TCAGCCGACG CCGCCTTCGC CAGCGAGTTC 
ATCAACATCG ACGGACTGGT GACGCTGGCA CGACTGGTGG AGAGCGGCAC TCATTTCGGG 
GAGATGCTGG CCTTCACTCT GACGGCGTTT CTGGAGCTGA TGGATCATGG GATTGTGTCG 
TGGGAGCTGC TCTCACTGTC CTTCATCAAA CAGATTGCAG GTTACGTGAA CCAGCCGATG 
GTAGACGTGT CGATCCTGCA GCGCTCGCTG GCCATCCTGG AGAGTATGGT GTTGAACAGC 
CACAGCCTGT ACCAGCGGGT GGCGCAGGAG ACCACAGTCG CACAACTCAT CACACACCTG 
TCCAACCAGG AGATCCAGAC GTACGCCATC GCCCTCATCA ACGCCCTGTT CCTCAAAACC 
CCGGAGGACC GACGCCAGGA GATGGCGGCG ACGCTGGCTC AGAGACACCT GCGCGCCATC 
ATCCTCAATC ACATCATCCG GGGGAACCGG CCCGTGAAGG CGGAGATGGC GCATCAGCTG 
TACGTGCTGC AGGTGCTGAC CTTTAACCTT CTGGAGGAGC GCATGATGAC CAAGATGGAC 
CCCAATGACC AGACTCAGAG AGATGTGATC TTCGAGCTGC GCAGGATTGC GTTTGATGGA 
GACGCAGCAG AACCCAGCGG AACCGAGAAG AGGAAAGCGG CGGCCCACAC CAAAGACTAC 
AGGATGCTGG GATTCAGCAA TGCAGTGAAT CCTGCGCTGG ACTTCACCCA GACGCCGCCG 
GGGATGCTGG CGCTGGACAA CATGCTGTAC CTGGCCAAAC TACACCAGGA CACATACATC 
AGGATTGTTC TGGAAAACAG CAGTCGTGAG GATAAGCACG AGTGTCCGTT CGCGCGCTGT 
GCTATCGAGC TGACGCGGGT GCTGTGTGAT ATTCTGCAGG TCGGAGAGCT GCCGAATGAA 
GGCTGTAATG ACTTCCACCC CATGTTCTTC ACACACGAGC GCGCCTGGGA AGAGTTCTTC 
TGCGTCTGCA TACAGCTGCT CAACAAGACA TGGAAGGAGA TGAGGGCCAC TGCTGAAGAC 
TTCAACAAGG TGATGACGGT GGTGCGTGAG CAGATCACCC GGGCTCTGGC CCTGAAGCCT 
GCGTCTCTGG ATCAGCTGCG GCTGAAGCTG CGCTCTCTGA GTTACTCTGA GATTCTGCGA 
CTGCGTCAGT CCGAGAGAAT GAGCCAAGAT GACTTCCAGT CGCCGCCCAT CATTGAGCTG 
CGGGAGCGGA TCCAGCCGGA GATCCTGGAG CTCATCAAGC AGCAGAGGCT CAGTCGGCTC 
TGTGAGGGAA GCTGCTTCCG CAAACTGGGG AACCGACGCC GGCAGGAGAA GTTCTGGTTC 
TGCCGGCTCT CACTGAACCA CAAGCTGCTC CATTATGGGG ATCTGGAGGA GTCTCCACAG 
GGTGAGGTGC CACTGGAGCT GCTGACCGAC AAGATCGCCG TGTCCGACAT TAAAGCTGTG 
CTGACGGGGA AAGACTGTCC GCATATGAAG GAGAAGAGCG CGCTCAAGCA GAACAAGGAA 
GTGTTGGAGC TGGCGTTCTC CATCCTCTAC GACCCTGACG AGTCCCTCAA CTTCGTGGCA 
CCAAACAAAT ATGAGTACTG TATCTGGACA GACGGCCTGT CAGCTCTGCT AGGGAAGGAT 
CTGTCCAGTG ACCTCACACG AAGTGACCTT GACACACTAA TGAGTATGGA GATGAAGCTC 
CGCCTCCTGG ACCTGGAGAA CATCACCATC CCTGAGGCTC CGCCCCCCGT GCCCAAAGAG 
CCCAGCAGCT ACAACTTCAG CTACAACTAC GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Evolution of complexity in the zebrafish synapse proteome.
Nature communications814613(2017 Mar)
Bay?s ?,Collins MO,Reig-Viader R,Gou G,Goulding D,Izquierdo A,Choudhary JS,Emes RD,Grant SG

Loss-of-Function Mutations in ELMO2 Cause Intraosseous Vascular Malformation by Impeding RAC1 Signaling.
American journal of human genetics99(2)299-317(2016 Aug)
Cetinkaya A,Xiong JR,Vargel ?,K?semehmeto?lu K,Canter H?,Gerdan ?F,Longo N,Alzahrani A,Camps MP,Taskiran EZ,Laupheimer S,Botto LD,Paramalingam E,Gormez Z,Uz E,Yuksel B,Ruacan ?,Sa??ro?lu M?,Takahashi T,Reversade B,Akarsu NA

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

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elmo2 cDNA ORF clone, Danio rerio(zebrafish)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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