spop cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	spop
Entrez Gene ID	100005514
Full Name	speckle-type POZ protein
Synonyms	zgc:64140
General protein information	Preferred Names speckle-type POZ protein Names speckle-type POZ protein HIB homolog 1 SPOP1
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_201130.1	NP_957424.1	speckle-type POZ protein

Pathways from BioSystems

Homologies

	SPOP	XP_002800447.1
Canis lupus familiaris (dog)	SPOP	XP_005624685.1
Mus musculus (house mouse)	Spop	NP_079563.2
Gallus gallus (chicken)	SPOP	XP_423281.2
Arabidopsis thaliana (thale cress)	BPM4	NP_566212.2
Homo sapiens (human)	SPOP	NP_001007229.1
Pan troglodytes (chimpanzee)	SPOP	XP_001168026.1
Rattus norvegicus (Norway rat)	Spop	NP_001093966.1
Bos taurus (cattle)	SPOP	NP_001069404.1
Danio rerio (zebrafish)	spop	NP_957424.1
Drosophila melanogaster (fruit fly)	rdx	NP_650325.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP003428	XP_311713.5
Oryza sativa (rice)	Os03g0792500	NP_001051524.1
Caenorhabditis elegans (roundworm)	bath-43	NP_001022765.1
Oryza sativa (rice)	Os07g0167200	NP_001058976.1
Xenopus tropicalis (tropical clawed frog)	spop	NP_989003.1

Gene Ontology
Bibliography

Related articles in PubMed

Zebrafish Collagen Type I: Molecular and Biochemical Characterization of the Major Structural Protein in Bone and Skin.
Gistelinck C, Gioia R, Gagliardi A, Tonelli F, Marchese L, Bianchi L, Landi C, Bini L, Huysseune A, Witten PE, Staes A, Gevaert K, De Rocker N, Menten B, Malfait F, Leikin S, Carra S, Tenni R, Rossi A, De Paepe A, Coucke P, Willaert A, Forlino A
Scientific reports621540(2016 Feb)

SPOP mutation leads to genomic instability in prostate cancer.
Boysen G, Barbieri CE, Prandi D, Blattner M, Chae SS, Dahija A, Nataraj S, Huang D, Marotz C, Xu L, Huang J, Lecca P, Chhangawala S, Liu D, Zhou P, Sboner A, de Bono JS, Demichelis F, Houvras Y, Rubin MA
eLife4(2015 Sep)

Zebrafish rest regulates developmental gene expression but not neurogenesis.
Kok FO, Taibi A, Wanner SJ, Xie X, Moravec CE, Love CE, Prince VE, Mumm JS, Sirotkin HI
Development (Cambridge, England)139(20)3838-48(2012 Oct)

A hedgehog-induced BTB protein modulates hedgehog signaling by degrading Ci/Gli transcription factor.
Zhang Q, Zhang L, Wang B, Ou CY, Chien CT, Jiang J
Developmental cell10(6)719-29(2006 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following spop gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the spop cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa38424	NM_201130.1 Latest version!	Danio rerio speckle type BTB/POZ protein (spop), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

spop ( NM_201130.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_957424.1 Danio rerio speckle type BTB/POZ protein (spop), mRNA.

Price & Availability↑

CloneID	ODa38424
Clone ID Related Accession (Same CDS sequence)	NM_201130.1
Accession Version	NM_201130.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1125bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-08
Organism	Danio rerio(zebrafish)
Product	speckle-type POZ protein
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC053276.1. On Mar 1, 2008 this sequence version replaced XM_001344511.1. ##Evidence-Data-START## Transcript exon combination :: BC053276.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2168446, SAMEA2168447 [ECO:0000350] ##Evidence-Data-END##

ATGTCCAGGG TGCCGAGTCC TCCCCCTCCT GCAGAAATGA CCAGCGGCCC TGTGGCCGAA 
AGCTGGTGTT ACACACAGAT CAAAGTGGTT AAGTTCTCCT ATATGTGGAC CATCAACAAC 
TTCAGCTTCT GTCGGGAGGA GATGGGAGAG GTCATCAAAA GCTCCACCTT CTCCTCGGGG 
GCCAATGACA AACTCAAATG GTGTTTACGA GTGAATCCTA AAGGGCTGGA TGAGGAGAGT 
AAAGATTATC TGTCTCTCTA TCTGCTCCTG GTCAGCTGTC CTAAGAGTGA GGTTCGAGCC 
AAGTTCAAGT TCTCCATCCT TAACGCCAAG GGCGAGGAAA CCAAAGCTAT GGAGAGCCAA 
CGGGCATATC GCTTCGTGCA AGGGAAAGAC TGGGGTTTCA AGAAGTTCAT AAGGCGAGAC 
TTTCTTCTAG ATGAGGCCAA CGGGCTGCTG CCTGATGACA AGTTAACGCT CTTCTGTGAG 
GTGAGTGTGG TGCAGGACTC AGTGAACATC TCTGGGCAGA ACACAATGAA CATGGTGAAG 
GTTCCTGACT GCCGGCTGGC AGACGAACTT GGCGGACTGT GGGAACATTC TAGATTCACA 
GACTGCTCAC TGTGTGTCGC CGGCCAGGAG TTCCAGGCAC ACAAGGCCAT TCTGGCAGCA 
CGTTCTCCAG TATTCAGCGC TATGTTTGAA CACGAGATGG AGGAGAGTAA AAAGAACCGA 
GTTGAGATAA ATGACGTGGA GGCTGAGGTC TTCAAAGAGA TGATGTTCTT CATCTACACT 
GGCAAAGCAC CCAACCTGGA CAAGATGGCT GACGACCTGC TTGCTGCTGC TGACAAGTAT 
GCTCTGGAGC GGCTGAAGGT GATGTGTGAG GACGCGCTGT GCACCAGTCT GTCTGTGGAA 
AACGCAGCAG AGATTTTGAT CTTGGCCGAC CTGCACAGTG CAGACCAGCT CAAGACACAG 
GCTGTGGACT TTATCAACTA CCATGCATCT GATGTAATGG AGACTTCGGG GTGGAAGTCA 
ATGGTGGCGT CTCACCCTCA CCTGGTTGCC GAAGCATACC GTTCACTGGC CTCCGCCCAG 
TGCCCTTTCC TGGGTCCTCC CCGCAAACGG CTCAAACAGT CTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_957424.1
CDS	269..1393
Translation	MSRVPSPPPPAEMTSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPDCRLADELGGLWEHSRFTDCSLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEAEVFKEMMFFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCTSLSVENAAEILILADLHSADQLKTQAVDFINYHASDVMETSGWKSMVASHPHLVAEAYRSLASAQCPFLGPPRKRLKQS

Target ORF information:

RefSeq Version	NM_201130.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio speckle type BTB/POZ protein (spop), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_201130.1

ORF Insert Sequence:

ATGTCCAGGG TGCCGAGTCC TCCCCCTCCT GCAGAAATGA CCAGCGGCCC TGTGGCCGAA 
AGCTGGTGTT ACACACAGAT CAAAGTGGTT AAGTTCTCCT ATATGTGGAC CATCAACAAC 
TTCAGCTTCT GTCGGGAGGA GATGGGAGAG GTCATCAAAA GCTCCACCTT CTCCTCGGGG 
GCCAATGACA AACTCAAATG GTGTTTACGA GTGAATCCTA AAGGGCTGGA TGAGGAGAGT 
AAAGATTATC TGTCTCTCTA TCTGCTCCTG GTCAGCTGTC CTAAGAGTGA GGTTCGAGCC 
AAGTTCAAGT TCTCCATCCT TAACGCCAAG GGCGAGGAAA CCAAAGCTAT GGAGAGCCAA 
CGGGCATATC GCTTCGTGCA AGGGAAAGAC TGGGGTTTCA AGAAGTTCAT AAGGCGAGAC 
TTTCTTCTAG ATGAGGCCAA CGGGCTGCTG CCTGATGACA AGTTAACGCT CTTCTGTGAG 
GTGAGTGTGG TGCAGGACTC AGTGAACATC TCTGGGCAGA ACACAATGAA CATGGTGAAG 
GTTCCTGACT GCCGGCTGGC AGACGAACTT GGCGGACTGT GGGAACATTC TAGATTCACA 
GACTGCTCAC TGTGTGTCGC CGGCCAGGAG TTCCAGGCAC ACAAGGCCAT TCTGGCAGCA 
CGTTCTCCAG TATTCAGCGC TATGTTTGAA CACGAGATGG AGGAGAGTAA AAAGAACCGA 
GTTGAGATAA ATGACGTGGA GGCTGAGGTC TTCAAAGAGA TGATGTTCTT CATCTACACT 
GGCAAAGCAC CCAACCTGGA CAAGATGGCT GACGACCTGC TTGCTGCTGC TGACAAGTAT 
GCTCTGGAGC GGCTGAAGGT GATGTGTGAG GACGCGCTGT GCACCAGTCT GTCTGTGGAA 
AACGCAGCAG AGATTTTGAT CTTGGCCGAC CTGCACAGTG CAGACCAGCT CAAGACACAG 
GCTGTGGACT TTATCAACTA CCATGCATCT GATGTAATGG AGACTTCGGG GTGGAAGTCA 
ATGGTGGCGT CTCACCCTCA CCTGGTTGCC GAAGCATACC GTTCACTGGC CTCCGCCCAG 
TGCCCTTTCC TGGGTCCTCC CCGCAAACGG CTCAAACAGT CTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Zebrafish Collagen Type I: Molecular and Biochemical Characterization of the Major Structural Protein in Bone and Skin.
Scientific reports621540(2016 Feb)
Gistelinck C,Gioia R,Gagliardi A,Tonelli F,Marchese L,Bianchi L,Landi C,Bini L,Huysseune A,Witten PE,Staes A,Gevaert K,De Rocker N,Menten B,Malfait F,Leikin S,Carra S,Tenni R,Rossi A,De Paepe A,Coucke P,Willaert A,Forlino A

SPOP mutation leads to genomic instability in prostate cancer.
eLife4(2015 Sep)
Boysen G,Barbieri CE,Prandi D,Blattner M,Chae SS,Dahija A,Nataraj S,Huang D,Marotz C,Xu L,Huang J,Lecca P,Chhangawala S,Liu D,Zhou P,Sboner A,de Bono JS,Demichelis F,Houvras Y,Rubin MA

Zebrafish rest regulates developmental gene expression but not neurogenesis.
Development (Cambridge, England)139(20)3838-48(2012 Oct)
Kok FO,Taibi A,Wanner SJ,Xie X,Moravec CE,Love CE,Prince VE,Mumm JS,Sirotkin HI

A hedgehog-induced BTB protein modulates hedgehog signaling by degrading Ci/Gli transcription factor.
Developmental cell10(6)719-29(2006 Jun)
Zhang Q,Zhang L,Wang B,Ou CY,Chien CT,Jiang J

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spop cDNA ORF clone, Danio rerio(zebrafish)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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