EIF2AK2 cDNA ORF clone, Canis lupus familiaris(Dog)

Gene
Clones
gRNAs

Summary

Gene Symbol	EIF2AK2
Entrez Gene ID	611397
Full Name	eukaryotic translation initiation factor 2 alpha kinase 2
General protein information	Preferred Names eukaryotic translation initiation factor 2 alpha kinase 2 Names interferon-induced, double-stranded RNA-activated protein kinase P1/eIF-2A protein kinase interferon-inducible RNA-dependent protein kinase p68 kinase
Gene Type	protein-coding
Organism	Canis lupus familiaris(Dog)

mRNA and Protein(s)

mRNA	Protein	Name
XM_005630078.3	XP_005630135.1	interferon-induced, double-stranded RNA-activated protein kinase isoform X1
XM_022404347.1	XP_022260055.1	interferon-induced, double-stranded RNA-activated protein kinase isoform X1
XM_022404348.1	XP_022260056.1	interferon-induced, double-stranded RNA-activated protein kinase isoform X2
NM_001048135.1	NP_001041600.1	interferon-induced, double-stranded RNA-activated protein kinase
XM_005630079.2	XP_005630136.1	interferon-induced, double-stranded RNA-activated protein kinase isoform X1
XM_005630078.2	XP_005630135.1	interferon-induced, double-stranded RNA-activated protein kinase isoform X1

Pathways from BioSystems

Homologies

	EIF2AK2	NP_001077417.1
Canis lupus familiaris (dog)	EIF2AK2	NP_001041600.1
Homo sapiens (human)	EIF2AK2	NP_002750.1
Pan troglodytes (chimpanzee)	EIF2AK2	NP_001138509.1
Gallus gallus (chicken)	EIF2AK2	NP_989818.1
Xenopus tropicalis (tropical clawed frog)	pkr3	XP_002933926.1
Bos taurus (cattle)	EIF2AK2	NP_835210.2
Rattus norvegicus (Norway rat)	Eif2ak2	NP_062208.1
Xenopus tropicalis (tropical clawed frog)	eif2ak2	NP_001072537.1
Mus musculus (house mouse)	Eif2ak2	NP_035293.1
Danio rerio (zebrafish)	eif2ak2	NP_001107942.1

Gene Ontology
Bibliography

Related articles in PubMed

Comparative analysis of vertebrate EIF2AK2 (PKR) genes and assignment of the equine gene to ECA15q24-q25 and the bovine gene to BTA11q12-q15.
Perelygin AA, Lear TL, Zharkikh AA, Brinton MA
Genetics, selection, evolution : GSE38(5)551-63(2006 Sep-Oct)

Respiratory syncytial virus induces TLR3 protein and protein kinase R, leading to increased double-stranded RNA responsiveness in airway epithelial cells.
Groskreutz DJ, Monick MM, Powers LS, Yarovinsky TO, Look DC, Hunninghake GW
Journal of immunology (Baltimore, Md. : 1950)176(3)1733-40(2006 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Respiratory syncytial virus, via an effect on TLR3 and protein kinase R, sensitizes airway epithelial cells to subsequent double-stranded (ds)RNA exposure.
Title: Respiratory syncytial virus induces TLR3 protein and protein kinase R, leading to increased double-stranded RNA responsiveness in airway epithelial cells.

The following EIF2AK2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the EIF2AK2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OCe18584	NM_001048135.1 Latest version!	Canis lupus familiaris eukaryotic translation initiation factor 2 alpha kinase 2 (EIF2AK2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00
OCe18584	XM_022404347.1 Latest version!	Canis lupus familiaris eukaryotic translation initiation factor 2 alpha kinase 2 (EIF2AK2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00
OCe18584	XM_005630079.2 Latest version!	Canis lupus familiaris eukaryotic translation initiation factor 2-alpha kinase 2 (EIF2AK2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00
OCe18584	XM_005630078.3 Latest version!	Canis lupus familiaris eukaryotic translation initiation factor 2 alpha kinase 2 (EIF2AK2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00
OCe294156	XM_022404348.1 Latest version!	Canis lupus familiaris eukaryotic translation initiation factor 2 alpha kinase 2 (EIF2AK2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$258.30 $369.00
View Old Accession Versions >>
OCe18584	XM_005630078.2	Canis lupus familiaris eukaryotic translation initiation factor 2-alpha kinase 2 (EIF2AK2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

EIF2AK2 ( NM_001048135.1 ) cDNA ORF clone, Canis lupus familiaris(Dog) -> NP_001041600.1 Canis lupus familiaris eukaryotic translation initiation factor 2 alpha kinase 2 (EIF2AK2), mRNA.

Price & Availability↑

CloneID	OCe18584
Clone ID Related Accession (Same CDS sequence)	XM_005630078.3 , XM_022404347.1 , NM_001048135.1 , XM_005630079.2 , XM_005630078.2
Accession Version	NM_001048135.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1599bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-22
Organism	Canis lupus familiaris(dog)
Product	interferon-induced, double-stranded RNA-activated protein kinase
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY906960.1. On Sep 15, 2006 this sequence version replaced XM_849059.1. ##Evidence-Data-START## Transcript exon combination :: AY906960.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA103936001, SAMEA103936002 [ECO:0000350] ##Evidence-Data-END##

ATGGCCAATC AGCGTCCACC AAGTTTTTTT ATTGAAGAAC TTAATATATT CTGTCAGAAG 
CACAGAAAGG TACTTAAGTA TAATGAACTG TCTAAGGAAG GACCTGCACA TAACTTAAGA 
TTTACATTCC AAGCTATCAT AGATGAGAGA GAATATCCAG AAGCTGAAGG TAAATCAAAG 
AAGGAGGCCA GAAATACTGC AGCCAAATTA GCTCTTGAAA TACTTCATAA AGAAAACAAG 
GCGGTTAGTT CTTTATCACT GCCAACAACA GATACTTCAG AAGGATTAGG ATTAGAAGGC 
GTTGGGAATT ACATAGGCCG TATGAATAGG CTTGCCCAGA AGGAACAACT ATCTGTAAAT 
TATGAACAAT GGGAATTGAA GGATTGTGGG CCAGAAAGAT TTCATTGCAG ATGCAAAATT 
GGACAGAAAG AATATGATAT TGGTAAAGGT GCTACTAAAC AAGAGGCAAA ACATTTGGCT 
GCTAAATTTG CATATGAACA GATACAGTCA GAGCAAACCT TAATGAATGC TGATTCTGGT 
TCTTGGACTA CTTCACCTAG TGACTCCAGG AACAACACTT TGATGAGAAG CCTATGTGCT 
TCAAAATCAC CACTTGAAAA TAATTTCTCA CCAAATTGTA ACAGGGACAA TGTAGACAAC 
TCTCCATCTT CTCTGAGCAA TGCCAGATAC AGTGAAAAGA AGGTGAAAAG AACTTTAGCA 
CCTACCTTTA GCTCTCCTAT GACCAAAGAA CACAAGTACA CAGTGGAACT CAGGTTTGCC 
AGTGATTTTA CAGAAATAGA ACCAATTGGC TCAGGTGGAT ATGGTCAAGT TTTCAAAGCA 
AAACACAAAA TTGATGGGAA GATTTATGTT ATTAAACGTG TTAAATACGA TAGCGACAAG 
AAGGTAGAAC GGGAAGTAAA AGCTTTGGCA GCGCTTGATC ACGTAAATAT CGTGCACTAC 
CGTAGTTGCT GGGCTGGGGA AGATTACAAT CCTGAGGACA GTGTAAATCC TTCAAGAACA 
ACTAAGTGCC TTTTCATCCA AATGGAATTC TGTGATAAAG GAACATTGGA GCAATGGATT 
GACAACAGAA GAGGCAAGGA ACAAGACAAA CCTTTGGCTC TGGAATTATT TGAACAAATA 
GTAGCAGGTG TGAATTATAT ACACAGCAAA CAGCTAATTC ACAGAGACCT TAAGCCAGGA 
AACATATTTT TAGTAGATAC AAAACACATA AAGATTGGAG ATTTTGGACT TGTGACATCC 
TTGAAAGATT TTGCAAATCG GACAAGTAAT AAAGGAACTC TTCGGTACAT GAGCCCAGAG 
CAGATTTCTT CACAAGAATA TGGAAAAGAA GTGGATATCT TTGCTTTGGG GCTAATTCTT 
GCAGAACTTC TTTACATATG TCCCACTGTT TCAGAAACAC TGAAGATTTT TAAAGAGCTA 
AGGGCTGGCA AGTTCTCAGA TGTGTTTGAT GCCAGAGAAA AACAACTTCT GCAAAAATTA 
CTATCACTTG AGCCCATGAA ACGACCTAAT GCATCTGAAA TACTGGAGAC TTTGAAGGAT 
TGGAAGAATG TTGCAGGAAA AAAGTCAAGG ACATATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001041600.1
CDS	73..1671
Translation	MANQRPPSFFIEELNIFCQKHRKVLKYNELSKEGPAHNLRFTFQAIIDEREYPEAEGKSKKEARNTAAKLALEILHKENKAVSSLSLPTTDTSEGLGLEGVGNYIGRMNRLAQKEQLSVNYEQWELKDCGPERFHCRCKIGQKEYDIGKGATKQEAKHLAAKFAYEQIQSEQTLMNADSGSWTTSPSDSRNNTLMRSLCASKSPLENNFSPNCNRDNVDNSPSSLSNARYSEKKVKRTLAPTFSSPMTKEHKYTVELRFASDFTEIEPIGSGGYGQVFKAKHKIDGKIYVIKRVKYDSDKKVEREVKALAALDHVNIVHYRSCWAGEDYNPEDSVNPSRTTKCLFIQMEFCDKGTLEQWIDNRRGKEQDKPLALELFEQIVAGVNYIHSKQLIHRDLKPGNIFLVDTKHIKIGDFGLVTSLKDFANRTSNKGTLRYMSPEQISSQEYGKEVDIFALGLILAELLYICPTVSETLKIFKELRAGKFSDVFDAREKQLLQKLLSLEPMKRPNASEILETLKDWKNVAGKKSRTY

Target ORF information:

RefSeq Version	NM_001048135.1
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris eukaryotic translation initiation factor 2 alpha kinase 2 (EIF2AK2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001048135.1

ORF Insert Sequence:

ATGGCCAATC AGCGTCCACC AAGTTTTTTT ATTGAAGAAC TTAATATATT CTGTCAGAAG 
CACAGAAAGG TACTTAAGTA TAATGAACTG TCTAAGGAAG GACCTGCACA TAACTTAAGA 
TTTACATTCC AAGCTATCAT AGATGAGAGA GAATATCCAG AAGCTGAAGG TAAATCAAAG 
AAGGAGGCCA GAAATACTGC AGCCAAATTA GCTCTTGAAA TACTTCATAA AGAAAACAAG 
GCGGTTAGTT CTTTATCACT GCCAACAACA GATACTTCAG AAGGATTAGG ATTAGAAGGC 
GTTGGGAATT ACATAGGCCG TATGAATAGG CTTGCCCAGA AGGAACAACT ATCTGTAAAT 
TATGAACAAT GGGAATTGAA GGATTGTGGG CCAGAAAGAT TTCATTGCAG ATGCAAAATT 
GGACAGAAAG AATATGATAT TGGTAAAGGT GCTACTAAAC AAGAGGCAAA ACATTTGGCT 
GCTAAATTTG CATATGAACA GATACAGTCA GAGCAAACCT TAATGAATGC TGATTCTGGT 
TCTTGGACTA CTTCACCTAG TGACTCCAGG AACAACACTT TGATGAGAAG CCTATGTGCT 
TCAAAATCAC CACTTGAAAA TAATTTCTCA CCAAATTGTA ACAGGGACAA TGTAGACAAC 
TCTCCATCTT CTCTGAGCAA TGCCAGATAC AGTGAAAAGA AGGTGAAAAG AACTTTAGCA 
CCTACCTTTA GCTCTCCTAT GACCAAAGAA CACAAGTACA CAGTGGAACT CAGGTTTGCC 
AGTGATTTTA CAGAAATAGA ACCAATTGGC TCAGGTGGAT ATGGTCAAGT TTTCAAAGCA 
AAACACAAAA TTGATGGGAA GATTTATGTT ATTAAACGTG TTAAATACGA TAGCGACAAG 
AAGGTAGAAC GGGAAGTAAA AGCTTTGGCA GCGCTTGATC ACGTAAATAT CGTGCACTAC 
CGTAGTTGCT GGGCTGGGGA AGATTACAAT CCTGAGGACA GTGTAAATCC TTCAAGAACA 
ACTAAGTGCC TTTTCATCCA AATGGAATTC TGTGATAAAG GAACATTGGA GCAATGGATT 
GACAACAGAA GAGGCAAGGA ACAAGACAAA CCTTTGGCTC TGGAATTATT TGAACAAATA 
GTAGCAGGTG TGAATTATAT ACACAGCAAA CAGCTAATTC ACAGAGACCT TAAGCCAGGA 
AACATATTTT TAGTAGATAC AAAACACATA AAGATTGGAG ATTTTGGACT TGTGACATCC 
TTGAAAGATT TTGCAAATCG GACAAGTAAT AAAGGAACTC TTCGGTACAT GAGCCCAGAG 
CAGATTTCTT CACAAGAATA TGGAAAAGAA GTGGATATCT TTGCTTTGGG GCTAATTCTT 
GCAGAACTTC TTTACATATG TCCCACTGTT TCAGAAACAC TGAAGATTTT TAAAGAGCTA 
AGGGCTGGCA AGTTCTCAGA TGTGTTTGAT GCCAGAGAAA AACAACTTCT GCAAAAATTA 
CTATCACTTG AGCCCATGAA ACGACCTAAT GCATCTGAAA TACTGGAGAC TTTGAAGGAT 
TGGAAGAATG TTGCAGGAAA AAAGTCAAGG ACATATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EIF2AK2 ( XM_005630078.3 ) cDNA ORF clone, Canis lupus familiaris(Dog) -> XP_005630135.1 Canis lupus familiaris eukaryotic translation initiation factor 2 alpha kinase 2 (EIF2AK2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OCe18584
Clone ID Related Accession (Same CDS sequence)	XM_005630078.3 , XM_022404347.1 , NM_001048135.1 , XM_005630079.2 , XM_005630078.2
Accession Version	XM_005630078.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1599bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-04
Organism	Canis lupus familiaris(dog)
Product	interferon-induced, double-stranded RNA-activated protein kinase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006599.3) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 5, 2017 this sequence version replaced XM_005630078.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCAATC AGCGTCCACC AAGTTTTTTT ATTGAAGAAC TTAATATATT CTGTCAGAAG 
CACAGAAAGG TACTTAAGTA TAATGAACTG TCTAAGGAAG GACCTGCACA TAACTTAAGA 
TTTACATTCC AAGCTATCAT AGATGAGAGA GAATATCCAG AAGCTGAAGG TAAATCAAAG 
AAGGAGGCCA GAAATACTGC AGCCAAATTA GCTCTTGAAA TACTTCATAA AGAAAACAAG 
GCGGTTAGTT CTTTATCACT GCCAACAACA GATACTTCAG AAGGATTAGG ATTAGAAGGC 
GTTGGGAATT ACATAGGCCG TATGAATAGG CTTGCCCAGA AGGAACAACT ATCTGTAAAT 
TATGAACAAT GGGAATTGAA GGATTGTGGG CCAGAAAGAT TTCATTGCAG ATGCAAAATT 
GGACAGAAAG AATATGATAT TGGTAAAGGT GCTACTAAAC AAGAGGCAAA ACATTTGGCT 
GCTAAATTTG CATATGAACA GATACAGTCA GAGCAAACCT TAATGAATGC TGATTCTGGT 
TCTTGGACTA CTTCACCTAG TGACTCCAGG AACAACACTT TGATGAGAAG CCTATGTGCT 
TCAAAATCAC CACTTGAAAA TAATTTCTCA CCAAATTGTA ACAGGGACAA TGTAGACAAC 
TCTCCATCTT CTCTGAGCAA TGCCAGATAC AGTGAAAAGA AGGTGAAAAG AACTTTAGCA 
CCTACCTTTA GCTCTCCTAT GACCAAAGAA CACAAGTACA CAGTGGAACT CAGGTTTGCC 
AGTGATTTTA CAGAAATAGA ACCAATTGGC TCAGGTGGAT ATGGTCAAGT TTTCAAAGCA 
AAACACAAAA TTGATGGGAA GATTTATGTT ATTAAACGTG TTAAATACGA TAGCGACAAG 
AAGGTAGAAC GGGAAGTAAA AGCTTTGGCA GCGCTTGATC ACGTAAATAT CGTGCACTAC 
CGTAGTTGCT GGGCTGGGGA AGATTACAAT CCTGAGGACA GTGTAAATCC TTCAAGAACA 
ACTAAGTGCC TTTTCATCCA AATGGAATTC TGTGATAAAG GAACATTGGA GCAATGGATT 
GACAACAGAA GAGGCAAGGA ACAAGACAAA CCTTTGGCTC TGGAATTATT TGAACAAATA 
GTAGCAGGTG TGAATTATAT ACACAGCAAA CAGCTAATTC ACAGAGACCT TAAGCCAGGA 
AACATATTTT TAGTAGATAC AAAACACATA AAGATTGGAG ATTTTGGACT TGTGACATCC 
TTGAAAGATT TTGCAAATCG GACAAGTAAT AAAGGAACTC TTCGGTACAT GAGCCCAGAG 
CAGATTTCTT CACAAGAATA TGGAAAAGAA GTGGATATCT TTGCTTTGGG GCTAATTCTT 
GCAGAACTTC TTTACATATG TCCCACTGTT TCAGAAACAC TGAAGATTTT TAAAGAGCTA 
AGGGCTGGCA AGTTCTCAGA TGTGTTTGAT GCCAGAGAAA AACAACTTCT GCAAAAATTA 
CTATCACTTG AGCCCATGAA ACGACCTAAT GCATCTGAAA TACTGGAGAC TTTGAAGGAT 
TGGAAGAATG TTGCAGGAAA AAAGTCAAGG ACATATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005630135.1
CDS	142..1740
Translation	MANQRPPSFFIEELNIFCQKHRKVLKYNELSKEGPAHNLRFTFQAIIDEREYPEAEGKSKKEARNTAAKLALEILHKENKAVSSLSLPTTDTSEGLGLEGVGNYIGRMNRLAQKEQLSVNYEQWELKDCGPERFHCRCKIGQKEYDIGKGATKQEAKHLAAKFAYEQIQSEQTLMNADSGSWTTSPSDSRNNTLMRSLCASKSPLENNFSPNCNRDNVDNSPSSLSNARYSEKKVKRTLAPTFSSPMTKEHKYTVELRFASDFTEIEPIGSGGYGQVFKAKHKIDGKIYVIKRVKYDSDKKVEREVKALAALDHVNIVHYRSCWAGEDYNPEDSVNPSRTTKCLFIQMEFCDKGTLEQWIDNRRGKEQDKPLALELFEQIVAGVNYIHSKQLIHRDLKPGNIFLVDTKHIKIGDFGLVTSLKDFANRTSNKGTLRYMSPEQISSQEYGKEVDIFALGLILAELLYICPTVSETLKIFKELRAGKFSDVFDAREKQLLQKLLSLEPMKRPNASEILETLKDWKNVAGKKSRTY

Target ORF information:

RefSeq Version	XM_005630078.3
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris eukaryotic translation initiation factor 2 alpha kinase 2 (EIF2AK2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005630078.3

ORF Insert Sequence:

ATGGCCAATC AGCGTCCACC AAGTTTTTTT ATTGAAGAAC TTAATATATT CTGTCAGAAG 
CACAGAAAGG TACTTAAGTA TAATGAACTG TCTAAGGAAG GACCTGCACA TAACTTAAGA 
TTTACATTCC AAGCTATCAT AGATGAGAGA GAATATCCAG AAGCTGAAGG TAAATCAAAG 
AAGGAGGCCA GAAATACTGC AGCCAAATTA GCTCTTGAAA TACTTCATAA AGAAAACAAG 
GCGGTTAGTT CTTTATCACT GCCAACAACA GATACTTCAG AAGGATTAGG ATTAGAAGGC 
GTTGGGAATT ACATAGGCCG TATGAATAGG CTTGCCCAGA AGGAACAACT ATCTGTAAAT 
TATGAACAAT GGGAATTGAA GGATTGTGGG CCAGAAAGAT TTCATTGCAG ATGCAAAATT 
GGACAGAAAG AATATGATAT TGGTAAAGGT GCTACTAAAC AAGAGGCAAA ACATTTGGCT 
GCTAAATTTG CATATGAACA GATACAGTCA GAGCAAACCT TAATGAATGC TGATTCTGGT 
TCTTGGACTA CTTCACCTAG TGACTCCAGG AACAACACTT TGATGAGAAG CCTATGTGCT 
TCAAAATCAC CACTTGAAAA TAATTTCTCA CCAAATTGTA ACAGGGACAA TGTAGACAAC 
TCTCCATCTT CTCTGAGCAA TGCCAGATAC AGTGAAAAGA AGGTGAAAAG AACTTTAGCA 
CCTACCTTTA GCTCTCCTAT GACCAAAGAA CACAAGTACA CAGTGGAACT CAGGTTTGCC 
AGTGATTTTA CAGAAATAGA ACCAATTGGC TCAGGTGGAT ATGGTCAAGT TTTCAAAGCA 
AAACACAAAA TTGATGGGAA GATTTATGTT ATTAAACGTG TTAAATACGA TAGCGACAAG 
AAGGTAGAAC GGGAAGTAAA AGCTTTGGCA GCGCTTGATC ACGTAAATAT CGTGCACTAC 
CGTAGTTGCT GGGCTGGGGA AGATTACAAT CCTGAGGACA GTGTAAATCC TTCAAGAACA 
ACTAAGTGCC TTTTCATCCA AATGGAATTC TGTGATAAAG GAACATTGGA GCAATGGATT 
GACAACAGAA GAGGCAAGGA ACAAGACAAA CCTTTGGCTC TGGAATTATT TGAACAAATA 
GTAGCAGGTG TGAATTATAT ACACAGCAAA CAGCTAATTC ACAGAGACCT TAAGCCAGGA 
AACATATTTT TAGTAGATAC AAAACACATA AAGATTGGAG ATTTTGGACT TGTGACATCC 
TTGAAAGATT TTGCAAATCG GACAAGTAAT AAAGGAACTC TTCGGTACAT GAGCCCAGAG 
CAGATTTCTT CACAAGAATA TGGAAAAGAA GTGGATATCT TTGCTTTGGG GCTAATTCTT 
GCAGAACTTC TTTACATATG TCCCACTGTT TCAGAAACAC TGAAGATTTT TAAAGAGCTA 
AGGGCTGGCA AGTTCTCAGA TGTGTTTGAT GCCAGAGAAA AACAACTTCT GCAAAAATTA 
CTATCACTTG AGCCCATGAA ACGACCTAAT GCATCTGAAA TACTGGAGAC TTTGAAGGAT 
TGGAAGAATG TTGCAGGAAA AAAGTCAAGG ACATATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EIF2AK2 ( XM_022404347.1 ) cDNA ORF clone, Canis lupus familiaris(Dog) -> XP_022260055.1 Canis lupus familiaris eukaryotic translation initiation factor 2 alpha kinase 2 (EIF2AK2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OCe18584
Clone ID Related Accession (Same CDS sequence)	XM_005630078.3 , XM_022404347.1 , NM_001048135.1 , XM_005630079.2 , XM_005630078.2
Accession Version	XM_022404347.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1599bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-04
Organism	Canis lupus familiaris(dog)
Product	interferon-induced, double-stranded RNA-activated protein kinase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006599.3) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCAATC AGCGTCCACC AAGTTTTTTT ATTGAAGAAC TTAATATATT CTGTCAGAAG 
CACAGAAAGG TACTTAAGTA TAATGAACTG TCTAAGGAAG GACCTGCACA TAACTTAAGA 
TTTACATTCC AAGCTATCAT AGATGAGAGA GAATATCCAG AAGCTGAAGG TAAATCAAAG 
AAGGAGGCCA GAAATACTGC AGCCAAATTA GCTCTTGAAA TACTTCATAA AGAAAACAAG 
GCGGTTAGTT CTTTATCACT GCCAACAACA GATACTTCAG AAGGATTAGG ATTAGAAGGC 
GTTGGGAATT ACATAGGCCG TATGAATAGG CTTGCCCAGA AGGAACAACT ATCTGTAAAT 
TATGAACAAT GGGAATTGAA GGATTGTGGG CCAGAAAGAT TTCATTGCAG ATGCAAAATT 
GGACAGAAAG AATATGATAT TGGTAAAGGT GCTACTAAAC AAGAGGCAAA ACATTTGGCT 
GCTAAATTTG CATATGAACA GATACAGTCA GAGCAAACCT TAATGAATGC TGATTCTGGT 
TCTTGGACTA CTTCACCTAG TGACTCCAGG AACAACACTT TGATGAGAAG CCTATGTGCT 
TCAAAATCAC CACTTGAAAA TAATTTCTCA CCAAATTGTA ACAGGGACAA TGTAGACAAC 
TCTCCATCTT CTCTGAGCAA TGCCAGATAC AGTGAAAAGA AGGTGAAAAG AACTTTAGCA 
CCTACCTTTA GCTCTCCTAT GACCAAAGAA CACAAGTACA CAGTGGAACT CAGGTTTGCC 
AGTGATTTTA CAGAAATAGA ACCAATTGGC TCAGGTGGAT ATGGTCAAGT TTTCAAAGCA 
AAACACAAAA TTGATGGGAA GATTTATGTT ATTAAACGTG TTAAATACGA TAGCGACAAG 
AAGGTAGAAC GGGAAGTAAA AGCTTTGGCA GCGCTTGATC ACGTAAATAT CGTGCACTAC 
CGTAGTTGCT GGGCTGGGGA AGATTACAAT CCTGAGGACA GTGTAAATCC TTCAAGAACA 
ACTAAGTGCC TTTTCATCCA AATGGAATTC TGTGATAAAG GAACATTGGA GCAATGGATT 
GACAACAGAA GAGGCAAGGA ACAAGACAAA CCTTTGGCTC TGGAATTATT TGAACAAATA 
GTAGCAGGTG TGAATTATAT ACACAGCAAA CAGCTAATTC ACAGAGACCT TAAGCCAGGA 
AACATATTTT TAGTAGATAC AAAACACATA AAGATTGGAG ATTTTGGACT TGTGACATCC 
TTGAAAGATT TTGCAAATCG GACAAGTAAT AAAGGAACTC TTCGGTACAT GAGCCCAGAG 
CAGATTTCTT CACAAGAATA TGGAAAAGAA GTGGATATCT TTGCTTTGGG GCTAATTCTT 
GCAGAACTTC TTTACATATG TCCCACTGTT TCAGAAACAC TGAAGATTTT TAAAGAGCTA 
AGGGCTGGCA AGTTCTCAGA TGTGTTTGAT GCCAGAGAAA AACAACTTCT GCAAAAATTA 
CTATCACTTG AGCCCATGAA ACGACCTAAT GCATCTGAAA TACTGGAGAC TTTGAAGGAT 
TGGAAGAATG TTGCAGGAAA AAAGTCAAGG ACATATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_022260055.1
CDS	148..1746
Translation	MANQRPPSFFIEELNIFCQKHRKVLKYNELSKEGPAHNLRFTFQAIIDEREYPEAEGKSKKEARNTAAKLALEILHKENKAVSSLSLPTTDTSEGLGLEGVGNYIGRMNRLAQKEQLSVNYEQWELKDCGPERFHCRCKIGQKEYDIGKGATKQEAKHLAAKFAYEQIQSEQTLMNADSGSWTTSPSDSRNNTLMRSLCASKSPLENNFSPNCNRDNVDNSPSSLSNARYSEKKVKRTLAPTFSSPMTKEHKYTVELRFASDFTEIEPIGSGGYGQVFKAKHKIDGKIYVIKRVKYDSDKKVEREVKALAALDHVNIVHYRSCWAGEDYNPEDSVNPSRTTKCLFIQMEFCDKGTLEQWIDNRRGKEQDKPLALELFEQIVAGVNYIHSKQLIHRDLKPGNIFLVDTKHIKIGDFGLVTSLKDFANRTSNKGTLRYMSPEQISSQEYGKEVDIFALGLILAELLYICPTVSETLKIFKELRAGKFSDVFDAREKQLLQKLLSLEPMKRPNASEILETLKDWKNVAGKKSRTY

Target ORF information:

RefSeq Version	XM_022404347.1
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris eukaryotic translation initiation factor 2 alpha kinase 2 (EIF2AK2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_022404347.1

ORF Insert Sequence:

ATGGCCAATC AGCGTCCACC AAGTTTTTTT ATTGAAGAAC TTAATATATT CTGTCAGAAG 
CACAGAAAGG TACTTAAGTA TAATGAACTG TCTAAGGAAG GACCTGCACA TAACTTAAGA 
TTTACATTCC AAGCTATCAT AGATGAGAGA GAATATCCAG AAGCTGAAGG TAAATCAAAG 
AAGGAGGCCA GAAATACTGC AGCCAAATTA GCTCTTGAAA TACTTCATAA AGAAAACAAG 
GCGGTTAGTT CTTTATCACT GCCAACAACA GATACTTCAG AAGGATTAGG ATTAGAAGGC 
GTTGGGAATT ACATAGGCCG TATGAATAGG CTTGCCCAGA AGGAACAACT ATCTGTAAAT 
TATGAACAAT GGGAATTGAA GGATTGTGGG CCAGAAAGAT TTCATTGCAG ATGCAAAATT 
GGACAGAAAG AATATGATAT TGGTAAAGGT GCTACTAAAC AAGAGGCAAA ACATTTGGCT 
GCTAAATTTG CATATGAACA GATACAGTCA GAGCAAACCT TAATGAATGC TGATTCTGGT 
TCTTGGACTA CTTCACCTAG TGACTCCAGG AACAACACTT TGATGAGAAG CCTATGTGCT 
TCAAAATCAC CACTTGAAAA TAATTTCTCA CCAAATTGTA ACAGGGACAA TGTAGACAAC 
TCTCCATCTT CTCTGAGCAA TGCCAGATAC AGTGAAAAGA AGGTGAAAAG AACTTTAGCA 
CCTACCTTTA GCTCTCCTAT GACCAAAGAA CACAAGTACA CAGTGGAACT CAGGTTTGCC 
AGTGATTTTA CAGAAATAGA ACCAATTGGC TCAGGTGGAT ATGGTCAAGT TTTCAAAGCA 
AAACACAAAA TTGATGGGAA GATTTATGTT ATTAAACGTG TTAAATACGA TAGCGACAAG 
AAGGTAGAAC GGGAAGTAAA AGCTTTGGCA GCGCTTGATC ACGTAAATAT CGTGCACTAC 
CGTAGTTGCT GGGCTGGGGA AGATTACAAT CCTGAGGACA GTGTAAATCC TTCAAGAACA 
ACTAAGTGCC TTTTCATCCA AATGGAATTC TGTGATAAAG GAACATTGGA GCAATGGATT 
GACAACAGAA GAGGCAAGGA ACAAGACAAA CCTTTGGCTC TGGAATTATT TGAACAAATA 
GTAGCAGGTG TGAATTATAT ACACAGCAAA CAGCTAATTC ACAGAGACCT TAAGCCAGGA 
AACATATTTT TAGTAGATAC AAAACACATA AAGATTGGAG ATTTTGGACT TGTGACATCC 
TTGAAAGATT TTGCAAATCG GACAAGTAAT AAAGGAACTC TTCGGTACAT GAGCCCAGAG 
CAGATTTCTT CACAAGAATA TGGAAAAGAA GTGGATATCT TTGCTTTGGG GCTAATTCTT 
GCAGAACTTC TTTACATATG TCCCACTGTT TCAGAAACAC TGAAGATTTT TAAAGAGCTA 
AGGGCTGGCA AGTTCTCAGA TGTGTTTGAT GCCAGAGAAA AACAACTTCT GCAAAAATTA 
CTATCACTTG AGCCCATGAA ACGACCTAAT GCATCTGAAA TACTGGAGAC TTTGAAGGAT 
TGGAAGAATG TTGCAGGAAA AAAGTCAAGG ACATATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EIF2AK2 ( XM_005630079.2 ) cDNA ORF clone, Canis lupus familiaris(Dog) -> XP_005630136.1 Canis lupus familiaris eukaryotic translation initiation factor 2-alpha kinase 2 (EIF2AK2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OCe18584
Clone ID Related Accession (Same CDS sequence)	XM_005630078.3 , XM_022404347.1 , NM_001048135.1 , XM_005630079.2 , XM_005630078.2
Accession Version	XM_005630079.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1599bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-09-16
Organism	Canis lupus familiaris(Dog)
Product	interferon-induced, double-stranded RNA-activated protein kinase isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003726089.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Sep 17, 2015 this sequence version replaced XM_005630079.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCAATC AGCGTCCACC AAGTTTTTTT ATTGAAGAAC TTAATATATT CTGTCAGAAG 
CACAGAAAGG TACTTAAGTA TAATGAACTG TCTAAGGAAG GACCTGCACA TAACTTAAGA 
TTTACATTCC AAGCTATCAT AGATGAGAGA GAATATCCAG AAGCTGAAGG TAAATCAAAG 
AAGGAGGCCA GAAATACTGC AGCCAAATTA GCTCTTGAAA TACTTCATAA AGAAAACAAG 
GCGGTTAGTT CTTTATCACT GCCAACAACA GATACTTCAG AAGGATTAGG ATTAGAAGGC 
GTTGGGAATT ACATAGGCCG TATGAATAGG CTTGCCCAGA AGGAACAACT ATCTGTAAAT 
TATGAACAAT GGGAATTGAA GGATTGTGGG CCAGAAAGAT TTCATTGCAG ATGCAAAATT 
GGACAGAAAG AATATGATAT TGGTAAAGGT GCTACTAAAC AAGAGGCAAA ACATTTGGCT 
GCTAAATTTG CATATGAACA GATACAGTCA GAGCAAACCT TAATGAATGC TGATTCTGGT 
TCTTGGACTA CTTCACCTAG TGACTCCAGG AACAACACTT TGATGAGAAG CCTATGTGCT 
TCAAAATCAC CACTTGAAAA TAATTTCTCA CCAAATTGTA ACAGGGACAA TGTAGACAAC 
TCTCCATCTT CTCTGAGCAA TGCCAGATAC AGTGAAAAGA AGGTGAAAAG AACTTTAGCA 
CCTACCTTTA GCTCTCCTAT GACCAAAGAA CACAAGTACA CAGTGGAACT CAGGTTTGCC 
AGTGATTTTA CAGAAATAGA ACCAATTGGC TCAGGTGGAT ATGGTCAAGT TTTCAAAGCA 
AAACACAAAA TTGATGGGAA GATTTATGTT ATTAAACGTG TTAAATACGA TAGCGACAAG 
AAGGTAGAAC GGGAAGTAAA AGCTTTGGCA GCGCTTGATC ACGTAAATAT CGTGCACTAC 
CGTAGTTGCT GGGCTGGGGA AGATTACAAT CCTGAGGACA GTGTAAATCC TTCAAGAACA 
ACTAAGTGCC TTTTCATCCA AATGGAATTC TGTGATAAAG GAACATTGGA GCAATGGATT 
GACAACAGAA GAGGCAAGGA ACAAGACAAA CCTTTGGCTC TGGAATTATT TGAACAAATA 
GTAGCAGGTG TGAATTATAT ACACAGCAAA CAGCTAATTC ACAGAGACCT TAAGCCAGGA 
AACATATTTT TAGTAGATAC AAAACACATA AAGATTGGAG ATTTTGGACT TGTGACATCC 
TTGAAAGATT TTGCAAATCG GACAAGTAAT AAAGGAACTC TTCGGTACAT GAGCCCAGAG 
CAGATTTCTT CACAAGAATA TGGAAAAGAA GTGGATATCT TTGCTTTGGG GCTAATTCTT 
GCAGAACTTC TTTACATATG TCCCACTGTT TCAGAAACAC TGAAGATTTT TAAAGAGCTA 
AGGGCTGGCA AGTTCTCAGA TGTGTTTGAT GCCAGAGAAA AACAACTTCT GCAAAAATTA 
CTATCACTTG AGCCCATGAA ACGACCTAAT GCATCTGAAA TACTGGAGAC TTTGAAGGAT 
TGGAAGAATG TTGCAGGAAA AAAGTCAAGG ACATATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005630136.1
CDS	58..1656
Translation	MANQRPPSFFIEELNIFCQKHRKVLKYNELSKEGPAHNLRFTFQAIIDEREYPEAEGKSKKEARNTAAKLALEILHKENKAVSSLSLPTTDTSEGLGLEGVGNYIGRMNRLAQKEQLSVNYEQWELKDCGPERFHCRCKIGQKEYDIGKGATKQEAKHLAAKFAYEQIQSEQTLMNADSGSWTTSPSDSRNNTLMRSLCASKSPLENNFSPNCNRDNVDNSPSSLSNARYSEKKVKRTLAPTFSSPMTKEHKYTVELRFASDFTEIEPIGSGGYGQVFKAKHKIDGKIYVIKRVKYDSDKKVEREVKALAALDHVNIVHYRSCWAGEDYNPEDSVNPSRTTKCLFIQMEFCDKGTLEQWIDNRRGKEQDKPLALELFEQIVAGVNYIHSKQLIHRDLKPGNIFLVDTKHIKIGDFGLVTSLKDFANRTSNKGTLRYMSPEQISSQEYGKEVDIFALGLILAELLYICPTVSETLKIFKELRAGKFSDVFDAREKQLLQKLLSLEPMKRPNASEILETLKDWKNVAGKKSRTY

Target ORF information:

RefSeq Version	XM_005630079.2
Organism	Canis lupus familiaris(Dog)
Definition	Canis lupus familiaris eukaryotic translation initiation factor 2-alpha kinase 2 (EIF2AK2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005630079.2

ORF Insert Sequence:

ATGGCCAATC AGCGTCCACC AAGTTTTTTT ATTGAAGAAC TTAATATATT CTGTCAGAAG 
CACAGAAAGG TACTTAAGTA TAATGAACTG TCTAAGGAAG GACCTGCACA TAACTTAAGA 
TTTACATTCC AAGCTATCAT AGATGAGAGA GAATATCCAG AAGCTGAAGG TAAATCAAAG 
AAGGAGGCCA GAAATACTGC AGCCAAATTA GCTCTTGAAA TACTTCATAA AGAAAACAAG 
GCGGTTAGTT CTTTATCACT GCCAACAACA GATACTTCAG AAGGATTAGG ATTAGAAGGC 
GTTGGGAATT ACATAGGCCG TATGAATAGG CTTGCCCAGA AGGAACAACT ATCTGTAAAT 
TATGAACAAT GGGAATTGAA GGATTGTGGG CCAGAAAGAT TTCATTGCAG ATGCAAAATT 
GGACAGAAAG AATATGATAT TGGTAAAGGT GCTACTAAAC AAGAGGCAAA ACATTTGGCT 
GCTAAATTTG CATATGAACA GATACAGTCA GAGCAAACCT TAATGAATGC TGATTCTGGT 
TCTTGGACTA CTTCACCTAG TGACTCCAGG AACAACACTT TGATGAGAAG CCTATGTGCT 
TCAAAATCAC CACTTGAAAA TAATTTCTCA CCAAATTGTA ACAGGGACAA TGTAGACAAC 
TCTCCATCTT CTCTGAGCAA TGCCAGATAC AGTGAAAAGA AGGTGAAAAG AACTTTAGCA 
CCTACCTTTA GCTCTCCTAT GACCAAAGAA CACAAGTACA CAGTGGAACT CAGGTTTGCC 
AGTGATTTTA CAGAAATAGA ACCAATTGGC TCAGGTGGAT ATGGTCAAGT TTTCAAAGCA 
AAACACAAAA TTGATGGGAA GATTTATGTT ATTAAACGTG TTAAATACGA TAGCGACAAG 
AAGGTAGAAC GGGAAGTAAA AGCTTTGGCA GCGCTTGATC ACGTAAATAT CGTGCACTAC 
CGTAGTTGCT GGGCTGGGGA AGATTACAAT CCTGAGGACA GTGTAAATCC TTCAAGAACA 
ACTAAGTGCC TTTTCATCCA AATGGAATTC TGTGATAAAG GAACATTGGA GCAATGGATT 
GACAACAGAA GAGGCAAGGA ACAAGACAAA CCTTTGGCTC TGGAATTATT TGAACAAATA 
GTAGCAGGTG TGAATTATAT ACACAGCAAA CAGCTAATTC ACAGAGACCT TAAGCCAGGA 
AACATATTTT TAGTAGATAC AAAACACATA AAGATTGGAG ATTTTGGACT TGTGACATCC 
TTGAAAGATT TTGCAAATCG GACAAGTAAT AAAGGAACTC TTCGGTACAT GAGCCCAGAG 
CAGATTTCTT CACAAGAATA TGGAAAAGAA GTGGATATCT TTGCTTTGGG GCTAATTCTT 
GCAGAACTTC TTTACATATG TCCCACTGTT TCAGAAACAC TGAAGATTTT TAAAGAGCTA 
AGGGCTGGCA AGTTCTCAGA TGTGTTTGAT GCCAGAGAAA AACAACTTCT GCAAAAATTA 
CTATCACTTG AGCCCATGAA ACGACCTAAT GCATCTGAAA TACTGGAGAC TTTGAAGGAT 
TGGAAGAATG TTGCAGGAAA AAAGTCAAGG ACATATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EIF2AK2 ( XM_005630078.2 ) cDNA ORF clone, Canis lupus familiaris(Dog) -> XP_005630135.1 Canis lupus familiaris eukaryotic translation initiation factor 2-alpha kinase 2 (EIF2AK2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OCe18584
Clone ID Related Accession (Same CDS sequence)	XM_005630078.3 , XM_022404347.1 , NM_001048135.1 , XM_005630079.2 , XM_005630078.2
Accession Version	XM_005630078.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1599bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-09-16
Organism	Canis lupus familiaris(Dog)
Product	interferon-induced, double-stranded RNA-activated protein kinase isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003726089.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Sep 17, 2015 this sequence version replaced XM_005630078.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCAATC AGCGTCCACC AAGTTTTTTT ATTGAAGAAC TTAATATATT CTGTCAGAAG 
CACAGAAAGG TACTTAAGTA TAATGAACTG TCTAAGGAAG GACCTGCACA TAACTTAAGA 
TTTACATTCC AAGCTATCAT AGATGAGAGA GAATATCCAG AAGCTGAAGG TAAATCAAAG 
AAGGAGGCCA GAAATACTGC AGCCAAATTA GCTCTTGAAA TACTTCATAA AGAAAACAAG 
GCGGTTAGTT CTTTATCACT GCCAACAACA GATACTTCAG AAGGATTAGG ATTAGAAGGC 
GTTGGGAATT ACATAGGCCG TATGAATAGG CTTGCCCAGA AGGAACAACT ATCTGTAAAT 
TATGAACAAT GGGAATTGAA GGATTGTGGG CCAGAAAGAT TTCATTGCAG ATGCAAAATT 
GGACAGAAAG AATATGATAT TGGTAAAGGT GCTACTAAAC AAGAGGCAAA ACATTTGGCT 
GCTAAATTTG CATATGAACA GATACAGTCA GAGCAAACCT TAATGAATGC TGATTCTGGT 
TCTTGGACTA CTTCACCTAG TGACTCCAGG AACAACACTT TGATGAGAAG CCTATGTGCT 
TCAAAATCAC CACTTGAAAA TAATTTCTCA CCAAATTGTA ACAGGGACAA TGTAGACAAC 
TCTCCATCTT CTCTGAGCAA TGCCAGATAC AGTGAAAAGA AGGTGAAAAG AACTTTAGCA 
CCTACCTTTA GCTCTCCTAT GACCAAAGAA CACAAGTACA CAGTGGAACT CAGGTTTGCC 
AGTGATTTTA CAGAAATAGA ACCAATTGGC TCAGGTGGAT ATGGTCAAGT TTTCAAAGCA 
AAACACAAAA TTGATGGGAA GATTTATGTT ATTAAACGTG TTAAATACGA TAGCGACAAG 
AAGGTAGAAC GGGAAGTAAA AGCTTTGGCA GCGCTTGATC ACGTAAATAT CGTGCACTAC 
CGTAGTTGCT GGGCTGGGGA AGATTACAAT CCTGAGGACA GTGTAAATCC TTCAAGAACA 
ACTAAGTGCC TTTTCATCCA AATGGAATTC TGTGATAAAG GAACATTGGA GCAATGGATT 
GACAACAGAA GAGGCAAGGA ACAAGACAAA CCTTTGGCTC TGGAATTATT TGAACAAATA 
GTAGCAGGTG TGAATTATAT ACACAGCAAA CAGCTAATTC ACAGAGACCT TAAGCCAGGA 
AACATATTTT TAGTAGATAC AAAACACATA AAGATTGGAG ATTTTGGACT TGTGACATCC 
TTGAAAGATT TTGCAAATCG GACAAGTAAT AAAGGAACTC TTCGGTACAT GAGCCCAGAG 
CAGATTTCTT CACAAGAATA TGGAAAAGAA GTGGATATCT TTGCTTTGGG GCTAATTCTT 
GCAGAACTTC TTTACATATG TCCCACTGTT TCAGAAACAC TGAAGATTTT TAAAGAGCTA 
AGGGCTGGCA AGTTCTCAGA TGTGTTTGAT GCCAGAGAAA AACAACTTCT GCAAAAATTA 
CTATCACTTG AGCCCATGAA ACGACCTAAT GCATCTGAAA TACTGGAGAC TTTGAAGGAT 
TGGAAGAATG TTGCAGGAAA AAAGTCAAGG ACATATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005630135.1
CDS	207..1805
Translation	MANQRPPSFFIEELNIFCQKHRKVLKYNELSKEGPAHNLRFTFQAIIDEREYPEAEGKSKKEARNTAAKLALEILHKENKAVSSLSLPTTDTSEGLGLEGVGNYIGRMNRLAQKEQLSVNYEQWELKDCGPERFHCRCKIGQKEYDIGKGATKQEAKHLAAKFAYEQIQSEQTLMNADSGSWTTSPSDSRNNTLMRSLCASKSPLENNFSPNCNRDNVDNSPSSLSNARYSEKKVKRTLAPTFSSPMTKEHKYTVELRFASDFTEIEPIGSGGYGQVFKAKHKIDGKIYVIKRVKYDSDKKVEREVKALAALDHVNIVHYRSCWAGEDYNPEDSVNPSRTTKCLFIQMEFCDKGTLEQWIDNRRGKEQDKPLALELFEQIVAGVNYIHSKQLIHRDLKPGNIFLVDTKHIKIGDFGLVTSLKDFANRTSNKGTLRYMSPEQISSQEYGKEVDIFALGLILAELLYICPTVSETLKIFKELRAGKFSDVFDAREKQLLQKLLSLEPMKRPNASEILETLKDWKNVAGKKSRTY

Target ORF information:

RefSeq Version	XM_005630078.2
Organism	Canis lupus familiaris(Dog)
Definition	Canis lupus familiaris eukaryotic translation initiation factor 2-alpha kinase 2 (EIF2AK2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005630078.2

ORF Insert Sequence:

ATGGCCAATC AGCGTCCACC AAGTTTTTTT ATTGAAGAAC TTAATATATT CTGTCAGAAG 
CACAGAAAGG TACTTAAGTA TAATGAACTG TCTAAGGAAG GACCTGCACA TAACTTAAGA 
TTTACATTCC AAGCTATCAT AGATGAGAGA GAATATCCAG AAGCTGAAGG TAAATCAAAG 
AAGGAGGCCA GAAATACTGC AGCCAAATTA GCTCTTGAAA TACTTCATAA AGAAAACAAG 
GCGGTTAGTT CTTTATCACT GCCAACAACA GATACTTCAG AAGGATTAGG ATTAGAAGGC 
GTTGGGAATT ACATAGGCCG TATGAATAGG CTTGCCCAGA AGGAACAACT ATCTGTAAAT 
TATGAACAAT GGGAATTGAA GGATTGTGGG CCAGAAAGAT TTCATTGCAG ATGCAAAATT 
GGACAGAAAG AATATGATAT TGGTAAAGGT GCTACTAAAC AAGAGGCAAA ACATTTGGCT 
GCTAAATTTG CATATGAACA GATACAGTCA GAGCAAACCT TAATGAATGC TGATTCTGGT 
TCTTGGACTA CTTCACCTAG TGACTCCAGG AACAACACTT TGATGAGAAG CCTATGTGCT 
TCAAAATCAC CACTTGAAAA TAATTTCTCA CCAAATTGTA ACAGGGACAA TGTAGACAAC 
TCTCCATCTT CTCTGAGCAA TGCCAGATAC AGTGAAAAGA AGGTGAAAAG AACTTTAGCA 
CCTACCTTTA GCTCTCCTAT GACCAAAGAA CACAAGTACA CAGTGGAACT CAGGTTTGCC 
AGTGATTTTA CAGAAATAGA ACCAATTGGC TCAGGTGGAT ATGGTCAAGT TTTCAAAGCA 
AAACACAAAA TTGATGGGAA GATTTATGTT ATTAAACGTG TTAAATACGA TAGCGACAAG 
AAGGTAGAAC GGGAAGTAAA AGCTTTGGCA GCGCTTGATC ACGTAAATAT CGTGCACTAC 
CGTAGTTGCT GGGCTGGGGA AGATTACAAT CCTGAGGACA GTGTAAATCC TTCAAGAACA 
ACTAAGTGCC TTTTCATCCA AATGGAATTC TGTGATAAAG GAACATTGGA GCAATGGATT 
GACAACAGAA GAGGCAAGGA ACAAGACAAA CCTTTGGCTC TGGAATTATT TGAACAAATA 
GTAGCAGGTG TGAATTATAT ACACAGCAAA CAGCTAATTC ACAGAGACCT TAAGCCAGGA 
AACATATTTT TAGTAGATAC AAAACACATA AAGATTGGAG ATTTTGGACT TGTGACATCC 
TTGAAAGATT TTGCAAATCG GACAAGTAAT AAAGGAACTC TTCGGTACAT GAGCCCAGAG 
CAGATTTCTT CACAAGAATA TGGAAAAGAA GTGGATATCT TTGCTTTGGG GCTAATTCTT 
GCAGAACTTC TTTACATATG TCCCACTGTT TCAGAAACAC TGAAGATTTT TAAAGAGCTA 
AGGGCTGGCA AGTTCTCAGA TGTGTTTGAT GCCAGAGAAA AACAACTTCT GCAAAAATTA 
CTATCACTTG AGCCCATGAA ACGACCTAAT GCATCTGAAA TACTGGAGAC TTTGAAGGAT 
TGGAAGAATG TTGCAGGAAA AAAGTCAAGG ACATATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EIF2AK2 ( XM_022404348.1 ) cDNA ORF clone, Canis lupus familiaris(Dog) -> XP_022260056.1 Canis lupus familiaris eukaryotic translation initiation factor 2 alpha kinase 2 (EIF2AK2), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OCe294156
Clone ID Related Accession (Same CDS sequence)	XM_022404348.1
Accession Version	XM_022404348.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1476bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-04
Organism	Canis lupus familiaris(dog)
Product	interferon-induced, double-stranded RNA-activated protein kinase isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006599.3) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCAATC AGCGTCCACC AAGTTTTTTT ATTGAAGAAC TTAATATATT CTGTCAGAAG 
CACAGAAAGG TACTTAAGTA TAATGAACTG TCTAAGGAAG GACCTGCACA TAACTTAAGA 
TTTACATTCC AAGCTATCAT AGATGAGAGA GAATATCCAG AAGCTGAAGG TAAATCAAAG 
AAGGAGGCCA GAAATACTGC AGCCAAATTA GCTCTTGAAA TACTTCATAA AGAAAACAAG 
GCGGTTAGTT CTTTATCACT GCCAACAACA GATACTTCAG AAGGATTAGG ATTAGAAGGC 
GTTGGGAATT ACATAGGCCG TATGAATAGG CTTGCCCAGA AGGAACAACT ATCTGTAAAT 
TATGAACAAT GGGAATTGAA GGATTGTGGG CCAGAAAGAT TTCATTGCAG ATGCAAAATT 
GGACAGAAAG AATATGATAT TGGTAAAGGT GCTACTAAAC AAGAGGCAAA ACATTTGGCT 
GCTAAATTTG CATATGAACA GATACAGTCA GAGCAAACCT TAATGAATGC TGATTCTGGT 
TCTTGGACTA CTTCACCTAG TGACTCCAGG AACAACACTT TGATGAGAAG CCTATGTGCT 
TCAAAATCAC CACTTGAAAA TAATTTCTCA CCAAATTGTA ACAGGGACAA TGTAGACAAC 
TCTCCATCTT CTCTGAGCAA TGCCAGATAC AGTGAAAAGA AGGTGAAAAG AACTTTAGCA 
CCTACCTTTA GCTCTCCTAT GACCAAAGAA CACAAGTACA CAGTGGAACT CAGCAAGAAG 
GTAGAACGGG AAGTAAAAGC TTTGGCAGCG CTTGATCACG TAAATATCGT GCACTACCGT 
AGTTGCTGGG CTGGGGAAGA TTACAATCCT GAGGACAGTG TAAATCCTTC AAGAACAACT 
AAGTGCCTTT TCATCCAAAT GGAATTCTGT GATAAAGGAA CATTGGAGCA ATGGATTGAC 
AACAGAAGAG GCAAGGAACA AGACAAACCT TTGGCTCTGG AATTATTTGA ACAAATAGTA 
GCAGGTGTGA ATTATATACA CAGCAAACAG CTAATTCACA GAGACCTTAA GCCAGGAAAC 
ATATTTTTAG TAGATACAAA ACACATAAAG ATTGGAGATT TTGGACTTGT GACATCCTTG 
AAAGATTTTG CAAATCGGAC AAGTAATAAA GGAACTCTTC GGTACATGAG CCCAGAGCAG 
ATTTCTTCAC AAGAATATGG AAAAGAAGTG GATATCTTTG CTTTGGGGCT AATTCTTGCA 
GAACTTCTTT ACATATGTCC CACTGTTTCA GAAACACTGA AGATTTTTAA AGAGCTAAGG 
GCTGGCAAGT TCTCAGATGT GTTTGATGCC AGAGAAAAAC AACTTCTGCA AAAATTACTA 
TCACTTGAGC CCATGAAACG ACCTAATGCA TCTGAAATAC TGGAGACTTT GAAGGATTGG 
AAGAATGTTG CAGGAAAAAA GTCAAGGACA TATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_022260056.1
CDS	142..1617
Translation	MANQRPPSFFIEELNIFCQKHRKVLKYNELSKEGPAHNLRFTFQAIIDEREYPEAEGKSKKEARNTAAKLALEILHKENKAVSSLSLPTTDTSEGLGLEGVGNYIGRMNRLAQKEQLSVNYEQWELKDCGPERFHCRCKIGQKEYDIGKGATKQEAKHLAAKFAYEQIQSEQTLMNADSGSWTTSPSDSRNNTLMRSLCASKSPLENNFSPNCNRDNVDNSPSSLSNARYSEKKVKRTLAPTFSSPMTKEHKYTVELSKKVEREVKALAALDHVNIVHYRSCWAGEDYNPEDSVNPSRTTKCLFIQMEFCDKGTLEQWIDNRRGKEQDKPLALELFEQIVAGVNYIHSKQLIHRDLKPGNIFLVDTKHIKIGDFGLVTSLKDFANRTSNKGTLRYMSPEQISSQEYGKEVDIFALGLILAELLYICPTVSETLKIFKELRAGKFSDVFDAREKQLLQKLLSLEPMKRPNASEILETLKDWKNVAGKKSRTY

Target ORF information:

RefSeq Version	XM_022404348.1
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris eukaryotic translation initiation factor 2 alpha kinase 2 (EIF2AK2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_022404348.1

ORF Insert Sequence:

ATGGCCAATC AGCGTCCACC AAGTTTTTTT ATTGAAGAAC TTAATATATT CTGTCAGAAG 
CACAGAAAGG TACTTAAGTA TAATGAACTG TCTAAGGAAG GACCTGCACA TAACTTAAGA 
TTTACATTCC AAGCTATCAT AGATGAGAGA GAATATCCAG AAGCTGAAGG TAAATCAAAG 
AAGGAGGCCA GAAATACTGC AGCCAAATTA GCTCTTGAAA TACTTCATAA AGAAAACAAG 
GCGGTTAGTT CTTTATCACT GCCAACAACA GATACTTCAG AAGGATTAGG ATTAGAAGGC 
GTTGGGAATT ACATAGGCCG TATGAATAGG CTTGCCCAGA AGGAACAACT ATCTGTAAAT 
TATGAACAAT GGGAATTGAA GGATTGTGGG CCAGAAAGAT TTCATTGCAG ATGCAAAATT 
GGACAGAAAG AATATGATAT TGGTAAAGGT GCTACTAAAC AAGAGGCAAA ACATTTGGCT 
GCTAAATTTG CATATGAACA GATACAGTCA GAGCAAACCT TAATGAATGC TGATTCTGGT 
TCTTGGACTA CTTCACCTAG TGACTCCAGG AACAACACTT TGATGAGAAG CCTATGTGCT 
TCAAAATCAC CACTTGAAAA TAATTTCTCA CCAAATTGTA ACAGGGACAA TGTAGACAAC 
TCTCCATCTT CTCTGAGCAA TGCCAGATAC AGTGAAAAGA AGGTGAAAAG AACTTTAGCA 
CCTACCTTTA GCTCTCCTAT GACCAAAGAA CACAAGTACA CAGTGGAACT CAGCAAGAAG 
GTAGAACGGG AAGTAAAAGC TTTGGCAGCG CTTGATCACG TAAATATCGT GCACTACCGT 
AGTTGCTGGG CTGGGGAAGA TTACAATCCT GAGGACAGTG TAAATCCTTC AAGAACAACT 
AAGTGCCTTT TCATCCAAAT GGAATTCTGT GATAAAGGAA CATTGGAGCA ATGGATTGAC 
AACAGAAGAG GCAAGGAACA AGACAAACCT TTGGCTCTGG AATTATTTGA ACAAATAGTA 
GCAGGTGTGA ATTATATACA CAGCAAACAG CTAATTCACA GAGACCTTAA GCCAGGAAAC 
ATATTTTTAG TAGATACAAA ACACATAAAG ATTGGAGATT TTGGACTTGT GACATCCTTG 
AAAGATTTTG CAAATCGGAC AAGTAATAAA GGAACTCTTC GGTACATGAG CCCAGAGCAG 
ATTTCTTCAC AAGAATATGG AAAAGAAGTG GATATCTTTG CTTTGGGGCT AATTCTTGCA 
GAACTTCTTT ACATATGTCC CACTGTTTCA GAAACACTGA AGATTTTTAA AGAGCTAAGG 
GCTGGCAAGT TCTCAGATGT GTTTGATGCC AGAGAAAAAC AACTTCTGCA AAAATTACTA 
TCACTTGAGC CCATGAAACG ACCTAATGCA TCTGAAATAC TGGAGACTTT GAAGGATTGG 
AAGAATGTTG CAGGAAAAAA GTCAAGGACA TATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Comparative analysis of vertebrate EIF2AK2 (PKR) genes and assignment of the equine gene to ECA15q24-q25 and the bovine gene to BTA11q12-q15.
Genetics, selection, evolution : GSE38(5)551-63(2006 Sep-Oct)
Perelygin AA,Lear TL,Zharkikh AA,Brinton MA

Respiratory syncytial virus induces TLR3 protein and protein kinase R, leading to increased double-stranded RNA responsiveness in airway epithelial cells.
Journal of immunology (Baltimore, Md. : 1950)176(3)1733-40(2006 Feb)
Groskreutz DJ,Monick MM,Powers LS,Yarovinsky TO,Look DC,Hunninghake GW

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EIF2AK2 cDNA ORF clone, Canis lupus familiaris(Dog)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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