F7 cDNA ORF clone, Canis lupus familiaris(dog)

Gene
Clones
gRNAs

Summary

Gene Symbol	F7
Entrez Gene ID	607661
Full Name	coagulation factor VII
General protein information	Preferred Names coagulation factor VII Names coagulation factor VII coagulation factor VII (serum prothrombin conversion accelerator)
Gene Type	protein-coding
Organism	Canis lupus familiaris(dog)

mRNA and Protein(s)

mRNA	Protein	Name
XM_005634094.2	XP_005634151.1	coagulation factor VII isoform X2
NM_001048033.1	NP_001041498.1	coagulation factor VII precursor
XM_005634093.2	XP_005634150.1	coagulation factor VII isoform X1
XM_005634093.3	XP_005634150.1	coagulation factor VII isoform X1
XM_005634094.3	XP_005634151.1	coagulation factor VII isoform X2

Pathways from BioSystems

Homologies

Bos taurus (cattle)	F7	NP_001029978.1
Rattus norvegicus (Norway rat)	F7	NP_690059.1
Mus musculus (house mouse)	F7	NP_034302.2
	F7	NP_001073605.1
Gallus gallus (chicken)	F7	NP_989773.1
Homo sapiens (human)	F7	NP_062562.1
Pan troglodytes (chimpanzee)	F7	XP_001149885.2
Canis lupus familiaris (dog)	F7	NP_001041498.1
Danio rerio (zebrafish)	zgc:163025	NP_001083027.1
Xenopus tropicalis (tropical clawed frog)	f7	NP_001072819.1

Gene Ontology
Bibliography

Related articles in PubMed

Sustained correction of FVII deficiency in dogs using AAV-mediated expression of zymogen FVII.
Marcos-Contreras OA, Smith SM, Bellinger DA, Raymer RA, Merricks E, Faella A, Pavani G, Zhou S, Nichols TC, High KA, Margaritis P
Blood127(5)565-71(2016 Feb)

Characterization of canine coagulation factor?VII and its complex formation with tissue factor: canine-human cross-species compatibility.
Knudsen T, Kristensen AT, S?rensen BB, Olsen OH, Stennicke HR, Petersen LC
Journal of thrombosis and haemostasis : JTH8(8)1763-72(2010 Aug)

Successful treatment of canine hemophilia by continuous expression of canine FVIIa.
Margaritis P, Roy E, Aljamali MN, Downey HD, Giger U, Zhou S, Merricks E, Dillow A, Ezban M, Nichols TC, High KA
Blood113(16)3682-9(2009 Apr)

A novel missense mutation responsible for factor VII deficiency in research Beagle colonies.
Callan MB, Aljamali MN, Margaritis P, Griot-Wenk ME, Pollak ES, Werner P, Giger U, High KA
Journal of thrombosis and haemostasis : JTH4(12)2616-22(2006 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

F7-G96E dogs are a model of type I F7 deficiency. Canine F7 gene delivery in F7-G96E dogs via adeno-associated viral mediated expression of zymogen F7 at a dose effective in humans showed stable and clinically therapeutic F7 expression.
Title: Sustained correction of FVII deficiency in dogs using AAV-mediated expression of zymogen FVII.

analysis of coagulation factor VII and its complex formation with tissue factor in dog and human
Title: Characterization of canine coagulation factor?VII and its complex formation with tissue factor: canine-human cross-species compatibility.

Vector delivery via the portal vein in hemophilia A and B dogs was well tolerated, and long-term expression of cFVIIa resulted in a shortening of the prothrombin time, partial correction of the whole blood clotting time and thromboelastography parameters
Title: Successful treatment of canine hemophilia by continuous expression of canine FVIIa.

Identified missense mutation causing canine factor VII deficiency and altered blood coagulation.
Title: A novel missense mutation responsible for factor VII deficiency in research Beagle colonies.

The following F7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the F7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OCe34117	NM_001048033.1 Latest version!	Canis lupus familiaris coagulation factor VII (F7), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00
OCe23764	XM_005634093.3 Latest version!	Canis lupus familiaris coagulation factor VII (F7), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00
OCe23765	XM_005634094.3 Latest version!	Canis lupus familiaris coagulation factor VII (F7), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00
View Old Accession Versions >>
OCe23764	XM_005634093.2	Canis lupus familiaris coagulation factor VII (serum prothrombin conversion accelerator) (F7), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00
OCe23765	XM_005634094.2	Canis lupus familiaris coagulation factor VII (serum prothrombin conversion accelerator) (F7), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

F7 ( NM_001048033.1 ) cDNA ORF clone, Canis lupus familiaris(dog) -> NP_001041498.1 Canis lupus familiaris coagulation factor VII (F7), mRNA.

Price & Availability↑

CloneID	OCe34117
Clone ID Related Accession (Same CDS sequence)	NM_001048033.1
Accession Version	NM_001048033.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1341bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-21
Organism	Canis lupus familiaris(dog)
Product	coagulation factor VII precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from DQ223901.1. On Sep 14, 2006 this sequence version replaced XM_844420.1. ##Evidence-Data-START## Transcript exon combination :: DQ223901.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00013515, SAMN00013638 [ECO:0000348] ##Evidence-Data-END##

ATGGTTGCCT GGGCAGGTGA GCTGGCCCTC CTCTGCTTCC TACTGGGCCT GCAGGGGTCT 
CTGGCTGCAG TCTTCCTCAC CCAGGAGGAA GCCCAGGGTG TCCTGCACCG GCAAAGGCGC 
GCCAACTCGT TCCTGGAGGA GCTGCGGGCC GGCTCCCTGG AGAGAGAGTG CCGGGAGGAG 
CAGTGCTCCT TTGAGGAGGC CCGGGAGATC TTCCAGGACG TGGACAGGAC GAGGCAATTC 
TGGATTTCTT ACAAAGATGG GGACCAGTGC GCCTCGAATC CATGCCAGAA CGGAGGCTCC 
TGTGAGGACC AGCTCCAGTC CTACATCTGC TTCTGCCCCG ATGACTTCCA GGGCCGGAAC 
TGTGAGACAG ATAAGAAGGA CCAGCTGATC TGTATGAATG AGAATGGAGG CTGTCAGCAG 
TACTGCAGTG ACCACGCAGA GGCCAGGCGT TCCTGCTGGT GCCACGAGGG GTACACGCTC 
CAAGACGATG GAGTGTCCTG CATGCCCATA GTGGAATATC CGTGTGGAAA AATACCTGTT 
CTGGAGAAGA GAATTGGCAG CAACCCCCAA GGCCGAATTG TGGGTGGCAA AGTGTGCCCC 
AAAGGGGAGT GCCCCTGGCA GGCGGCAGTG AAGGTGGATG GGAAGCTGCT GTGTGGGGGC 
ACCCTGATCG ACGCTGCCTG GGTCGTCTCT GCAGCTCACT GCTTCGAAAG AATCAAGAAC 
TGGAAAAACC TGACTGTGGT GCTGGGCGAG CATGACCTCA GTGAGGACGA CGGCGATGAG 
CAGGAGCGGC ATGTGGCCCG GGTCATCGTC CCCGATAAGT ACATTCCCCT CAAGACGAAC 
CATGACATCG CCCTGCTGCA CCTGCGCACA CCCGTGGCCT ACACCGACCA TGTGGTGCCT 
CTGTGTCTGC CCGAGAAGAC CTTCTCCGAG AGGACGCTGG CCTTCATCCG CTTCTCAACC 
GTCAGCGGCT GGGGCCAGCT GCTTGACAGG GGCGCCACGG CCCTCCAGCT CATGGCCATC 
GACGTGCCTC GGGTGATGAC CCAGGACTGC CAGGAGCAGT CCCGCAGGAG AAGTGGCTCC 
CCCGCCATCA CTGAGAATAT GTTCTGTGCC GGCTACCTGG ACGGGAGCAA GGACGCCTGC 
CAGGGGGACA GCGGGGGCCC GCATGCCACG AAGTTCCAGG GCACATGGTA CCTGACAGGT 
GTCGTCAGCT GGGGGGAGGG CTGTGCGGCC GAAGGCCACT TTGGAGTGTA CACCAGGGTC 
TCCCAGTACA TCGAGTGGCT GCGCCAGCTC ATGGTCTCCA GCCATACCTT GAGAGGCCTC 
CTCCGGGCCC CACTGCCCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001041498.1
CDS	1..1341
Translation	MVAWAGELALLCFLLGLQGSLAAVFLTQEEAQGVLHRQRRANSFLEELRAGSLERECREEQCSFEEAREIFQDVDRTRQFWISYKDGDQCASNPCQNGGSCEDQLQSYICFCPDDFQGRNCETDKKDQLICMNENGGCQQYCSDHAEARRSCWCHEGYTLQDDGVSCMPIVEYPCGKIPVLEKRIGSNPQGRIVGGKVCPKGECPWQAAVKVDGKLLCGGTLIDAAWVVSAAHCFERIKNWKNLTVVLGEHDLSEDDGDEQERHVARVIVPDKYIPLKTNHDIALLHLRTPVAYTDHVVPLCLPEKTFSERTLAFIRFSTVSGWGQLLDRGATALQLMAIDVPRVMTQDCQEQSRRRSGSPAITENMFCAGYLDGSKDACQGDSGGPHATKFQGTWYLTGVVSWGEGCAAEGHFGVYTRVSQYIEWLRQLMVSSHTLRGLLRAPLP

Target ORF information:

RefSeq Version	NM_001048033.1
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris coagulation factor VII (F7), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001048033.1

ORF Insert Sequence:

ATGGTTGCCT GGGCAGGTGA GCTGGCCCTC CTCTGCTTCC TACTGGGCCT GCAGGGGTCT 
CTGGCTGCAG TCTTCCTCAC CCAGGAGGAA GCCCAGGGTG TCCTGCACCG GCAAAGGCGC 
GCCAACTCGT TCCTGGAGGA GCTGCGGGCC GGCTCCCTGG AGAGAGAGTG CCGGGAGGAG 
CAGTGCTCCT TTGAGGAGGC CCGGGAGATC TTCCAGGACG TGGACAGGAC GAGGCAATTC 
TGGATTTCTT ACAAAGATGG GGACCAGTGC GCCTCGAATC CATGCCAGAA CGGAGGCTCC 
TGTGAGGACC AGCTCCAGTC CTACATCTGC TTCTGCCCCG ATGACTTCCA GGGCCGGAAC 
TGTGAGACAG ATAAGAAGGA CCAGCTGATC TGTATGAATG AGAATGGAGG CTGTCAGCAG 
TACTGCAGTG ACCACGCAGA GGCCAGGCGT TCCTGCTGGT GCCACGAGGG GTACACGCTC 
CAAGACGATG GAGTGTCCTG CATGCCCATA GTGGAATATC CGTGTGGAAA AATACCTGTT 
CTGGAGAAGA GAATTGGCAG CAACCCCCAA GGCCGAATTG TGGGTGGCAA AGTGTGCCCC 
AAAGGGGAGT GCCCCTGGCA GGCGGCAGTG AAGGTGGATG GGAAGCTGCT GTGTGGGGGC 
ACCCTGATCG ACGCTGCCTG GGTCGTCTCT GCAGCTCACT GCTTCGAAAG AATCAAGAAC 
TGGAAAAACC TGACTGTGGT GCTGGGCGAG CATGACCTCA GTGAGGACGA CGGCGATGAG 
CAGGAGCGGC ATGTGGCCCG GGTCATCGTC CCCGATAAGT ACATTCCCCT CAAGACGAAC 
CATGACATCG CCCTGCTGCA CCTGCGCACA CCCGTGGCCT ACACCGACCA TGTGGTGCCT 
CTGTGTCTGC CCGAGAAGAC CTTCTCCGAG AGGACGCTGG CCTTCATCCG CTTCTCAACC 
GTCAGCGGCT GGGGCCAGCT GCTTGACAGG GGCGCCACGG CCCTCCAGCT CATGGCCATC 
GACGTGCCTC GGGTGATGAC CCAGGACTGC CAGGAGCAGT CCCGCAGGAG AAGTGGCTCC 
CCCGCCATCA CTGAGAATAT GTTCTGTGCC GGCTACCTGG ACGGGAGCAA GGACGCCTGC 
CAGGGGGACA GCGGGGGCCC GCATGCCACG AAGTTCCAGG GCACATGGTA CCTGACAGGT 
GTCGTCAGCT GGGGGGAGGG CTGTGCGGCC GAAGGCCACT TTGGAGTGTA CACCAGGGTC 
TCCCAGTACA TCGAGTGGCT GCGCCAGCTC ATGGTCTCCA GCCATACCTT GAGAGGCCTC 
CTCCGGGCCC CACTGCCCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

F7 ( XM_005634093.2 ) cDNA ORF clone, Canis lupus familiaris(dog) -> XP_005634150.1 Canis lupus familiaris coagulation factor VII (serum prothrombin conversion accelerator) (F7), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OCe23764
Clone ID Related Accession (Same CDS sequence)	XM_005634093.2 , XM_005634093.3
Accession Version	XM_005634093.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1386bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-09-16
Organism	Canis lupus familiaris(Dog)
Product	coagulation factor VII isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003726099.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 17, 2015 this sequence version replaced XM_005634093.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGTCTCA CCATGGTTGC CTGGGCAGGT GAGCTGGCCC TCCTCTGCTT CCTACTGGGC 
CTGCAGGGGT CTCTGGCTGC AGGGGTGTCG GTGCTCACGG GGACCCCCCC CCAAGTCTTC 
CTCACCCAGG AGGAAGCCCA GGGTGTCCTG CACCGGCAAA GGCGCGCCAA CTCGTTCCTG 
GAGGAGCTGC GGGCCGGCTC CCTGGAGAGA GAGTGCCGGG AGGAGCAGTG CTCCTTTGAG 
GAGGCCCGGG AGATCTTCCA GGACGTGGAC AGGACGAGGC AATTCTGGAT TTCTTACAAA 
GATGGGGACC AGTGCGCCTC GAATCCATGC CAGAACGGAG GCTCCTGTGA GGACCAGCTC 
CAGTCCTACA TCTGCTTCTG CCCCGATGAC TTCCAGGGCC GGAACTGTGA GACAAATAAG 
AAGGACCAGC TGATCTGTAT GAATGAGAAT GGAGGCTGTC AGCAGTACTG CAGTGACCAC 
GCAGAGGCCA GGCGTTCCTG CTGGTGCCAC GAGGGGTACA CGCTCCAAGA CGATGGAGTG 
TCCTGCATGC CCATAGTGGA ATATCCGTGT GGAAAAATAC CTGTTCTGGA GAAGAGAATT 
GGCAGCAACC CCCAAGGCCG AATTGTGGGT GGCAAAGTGT GCCCCAAAGG GGAGTGCCCC 
TGGCAGGCGG CAGTGAAGGT GGATGGGAAG CTGCTGTGTG GGGGCACCCT GATCGACGCT 
GCCTGGGTCG TCTCTGCAGC TCACTGCTTC GAAAGAATCA AGAACTGGAA AAACCTGACG 
GTGGTGCTGG GCGAGCATGA CCTCAGTGAG GACGACGGCG ATGAGCAGGA GCGGCATGTG 
GCCCAGGTCA TCGTCCCCGA TAAGTACATT CCCCTCAAGA CGAACCATGA CATCGCCCTG 
CTGCACCTGC GCACACCCGT GGCCTACACC GACCATGTGG TGCCTCTGTG TCTGCCCGAG 
AAGACCTTCT CCGAGAGGAC GCTGGCCTTC ATCCGCTTCT CAACCGTCAG CGGCTGGGGC 
CAGCTGCTTG ACAGGGGCGC CACGGCCCTC CAGCTCATGG CCATCGACGT GCCTCGGGTG 
ATGACCCAGG ACTGCCAGGA GCAGTCCCGC AGGAGAAGTG GCTCCCCCGC CATCACTGAG 
AATATGTTCT GTGCCGGCTA CCTGGACGGG AGCAAGGACG CCTGCCAGGG GGACAGCGGG 
GGCCCGCATG CCACGAAGTT CCAGGGCACA TGGTACCTGA CAGGTGTCGT CAGCTGGGGG 
GAGGGCTGTG CGGCCGAAGG CTACTTTGGA GTGTACACCA GGGTCTCCCA GTACATCGAG 
TGGCTGCGCC AGCTCATGGT CTCCAGCCAT ACCTTGAGAG GCCTCCTCCG GGCCCCACTG 
CCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005634150.1
CDS	22..1407
Translation	MGLTMVAWAGELALLCFLLGLQGSLAAGVSVLTGTPPQVFLTQEEAQGVLHRQRRANSFLEELRAGSLERECREEQCSFEEAREIFQDVDRTRQFWISYKDGDQCASNPCQNGGSCEDQLQSYICFCPDDFQGRNCETNKKDQLICMNENGGCQQYCSDHAEARRSCWCHEGYTLQDDGVSCMPIVEYPCGKIPVLEKRIGSNPQGRIVGGKVCPKGECPWQAAVKVDGKLLCGGTLIDAAWVVSAAHCFERIKNWKNLTVVLGEHDLSEDDGDEQERHVAQVIVPDKYIPLKTNHDIALLHLRTPVAYTDHVVPLCLPEKTFSERTLAFIRFSTVSGWGQLLDRGATALQLMAIDVPRVMTQDCQEQSRRRSGSPAITENMFCAGYLDGSKDACQGDSGGPHATKFQGTWYLTGVVSWGEGCAAEGYFGVYTRVSQYIEWLRQLMVSSHTLRGLLRAPLP

Target ORF information:

RefSeq Version	XM_005634093.2
Organism	Canis lupus familiaris(Dog)
Definition	Canis lupus familiaris coagulation factor VII (serum prothrombin conversion accelerator) (F7), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005634093.2

ORF Insert Sequence:

ATGGGTCTCA CCATGGTTGC CTGGGCAGGT GAGCTGGCCC TCCTCTGCTT CCTACTGGGC 
CTGCAGGGGT CTCTGGCTGC AGGGGTGTCG GTGCTCACGG GGACCCCCCC CCAAGTCTTC 
CTCACCCAGG AGGAAGCCCA GGGTGTCCTG CACCGGCAAA GGCGCGCCAA CTCGTTCCTG 
GAGGAGCTGC GGGCCGGCTC CCTGGAGAGA GAGTGCCGGG AGGAGCAGTG CTCCTTTGAG 
GAGGCCCGGG AGATCTTCCA GGACGTGGAC AGGACGAGGC AATTCTGGAT TTCTTACAAA 
GATGGGGACC AGTGCGCCTC GAATCCATGC CAGAACGGAG GCTCCTGTGA GGACCAGCTC 
CAGTCCTACA TCTGCTTCTG CCCCGATGAC TTCCAGGGCC GGAACTGTGA GACAAATAAG 
AAGGACCAGC TGATCTGTAT GAATGAGAAT GGAGGCTGTC AGCAGTACTG CAGTGACCAC 
GCAGAGGCCA GGCGTTCCTG CTGGTGCCAC GAGGGGTACA CGCTCCAAGA CGATGGAGTG 
TCCTGCATGC CCATAGTGGA ATATCCGTGT GGAAAAATAC CTGTTCTGGA GAAGAGAATT 
GGCAGCAACC CCCAAGGCCG AATTGTGGGT GGCAAAGTGT GCCCCAAAGG GGAGTGCCCC 
TGGCAGGCGG CAGTGAAGGT GGATGGGAAG CTGCTGTGTG GGGGCACCCT GATCGACGCT 
GCCTGGGTCG TCTCTGCAGC TCACTGCTTC GAAAGAATCA AGAACTGGAA AAACCTGACG 
GTGGTGCTGG GCGAGCATGA CCTCAGTGAG GACGACGGCG ATGAGCAGGA GCGGCATGTG 
GCCCAGGTCA TCGTCCCCGA TAAGTACATT CCCCTCAAGA CGAACCATGA CATCGCCCTG 
CTGCACCTGC GCACACCCGT GGCCTACACC GACCATGTGG TGCCTCTGTG TCTGCCCGAG 
AAGACCTTCT CCGAGAGGAC GCTGGCCTTC ATCCGCTTCT CAACCGTCAG CGGCTGGGGC 
CAGCTGCTTG ACAGGGGCGC CACGGCCCTC CAGCTCATGG CCATCGACGT GCCTCGGGTG 
ATGACCCAGG ACTGCCAGGA GCAGTCCCGC AGGAGAAGTG GCTCCCCCGC CATCACTGAG 
AATATGTTCT GTGCCGGCTA CCTGGACGGG AGCAAGGACG CCTGCCAGGG GGACAGCGGG 
GGCCCGCATG CCACGAAGTT CCAGGGCACA TGGTACCTGA CAGGTGTCGT CAGCTGGGGG 
GAGGGCTGTG CGGCCGAAGG CTACTTTGGA GTGTACACCA GGGTCTCCCA GTACATCGAG 
TGGCTGCGCC AGCTCATGGT CTCCAGCCAT ACCTTGAGAG GCCTCCTCCG GGCCCCACTG 
CCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

F7 ( XM_005634093.3 ) cDNA ORF clone, Canis lupus familiaris(dog) -> XP_005634150.1 Canis lupus familiaris coagulation factor VII (F7), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OCe23764
Clone ID Related Accession (Same CDS sequence)	XM_005634093.2 , XM_005634093.3
Accession Version	XM_005634093.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1386bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-04
Organism	Canis lupus familiaris(dog)
Product	coagulation factor VII isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006604.3) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 5, 2017 this sequence version replaced XM_005634093.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGTCTCA CCATGGTTGC CTGGGCAGGT GAGCTGGCCC TCCTCTGCTT CCTACTGGGC 
CTGCAGGGGT CTCTGGCTGC AGGGGTGTCG GTGCTCACGG GGACCCCCCC CCAAGTCTTC 
CTCACCCAGG AGGAAGCCCA GGGTGTCCTG CACCGGCAAA GGCGCGCCAA CTCGTTCCTG 
GAGGAGCTGC GGGCCGGCTC CCTGGAGAGA GAGTGCCGGG AGGAGCAGTG CTCCTTTGAG 
GAGGCCCGGG AGATCTTCCA GGACGTGGAC AGGACGAGGC AATTCTGGAT TTCTTACAAA 
GATGGGGACC AGTGCGCCTC GAATCCATGC CAGAACGGAG GCTCCTGTGA GGACCAGCTC 
CAGTCCTACA TCTGCTTCTG CCCCGATGAC TTCCAGGGCC GGAACTGTGA GACAAATAAG 
AAGGACCAGC TGATCTGTAT GAATGAGAAT GGAGGCTGTC AGCAGTACTG CAGTGACCAC 
GCAGAGGCCA GGCGTTCCTG CTGGTGCCAC GAGGGGTACA CGCTCCAAGA CGATGGAGTG 
TCCTGCATGC CCATAGTGGA ATATCCGTGT GGAAAAATAC CTGTTCTGGA GAAGAGAATT 
GGCAGCAACC CCCAAGGCCG AATTGTGGGT GGCAAAGTGT GCCCCAAAGG GGAGTGCCCC 
TGGCAGGCGG CAGTGAAGGT GGATGGGAAG CTGCTGTGTG GGGGCACCCT GATCGACGCT 
GCCTGGGTCG TCTCTGCAGC TCACTGCTTC GAAAGAATCA AGAACTGGAA AAACCTGACG 
GTGGTGCTGG GCGAGCATGA CCTCAGTGAG GACGACGGCG ATGAGCAGGA GCGGCATGTG 
GCCCAGGTCA TCGTCCCCGA TAAGTACATT CCCCTCAAGA CGAACCATGA CATCGCCCTG 
CTGCACCTGC GCACACCCGT GGCCTACACC GACCATGTGG TGCCTCTGTG TCTGCCCGAG 
AAGACCTTCT CCGAGAGGAC GCTGGCCTTC ATCCGCTTCT CAACCGTCAG CGGCTGGGGC 
CAGCTGCTTG ACAGGGGCGC CACGGCCCTC CAGCTCATGG CCATCGACGT GCCTCGGGTG 
ATGACCCAGG ACTGCCAGGA GCAGTCCCGC AGGAGAAGTG GCTCCCCCGC CATCACTGAG 
AATATGTTCT GTGCCGGCTA CCTGGACGGG AGCAAGGACG CCTGCCAGGG GGACAGCGGG 
GGCCCGCATG CCACGAAGTT CCAGGGCACA TGGTACCTGA CAGGTGTCGT CAGCTGGGGG 
GAGGGCTGTG CGGCCGAAGG CTACTTTGGA GTGTACACCA GGGTCTCCCA GTACATCGAG 
TGGCTGCGCC AGCTCATGGT CTCCAGCCAT ACCTTGAGAG GCCTCCTCCG GGCCCCACTG 
CCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005634150.1
CDS	41..1426
Translation	MGLTMVAWAGELALLCFLLGLQGSLAAGVSVLTGTPPQVFLTQEEAQGVLHRQRRANSFLEELRAGSLERECREEQCSFEEAREIFQDVDRTRQFWISYKDGDQCASNPCQNGGSCEDQLQSYICFCPDDFQGRNCETNKKDQLICMNENGGCQQYCSDHAEARRSCWCHEGYTLQDDGVSCMPIVEYPCGKIPVLEKRIGSNPQGRIVGGKVCPKGECPWQAAVKVDGKLLCGGTLIDAAWVVSAAHCFERIKNWKNLTVVLGEHDLSEDDGDEQERHVAQVIVPDKYIPLKTNHDIALLHLRTPVAYTDHVVPLCLPEKTFSERTLAFIRFSTVSGWGQLLDRGATALQLMAIDVPRVMTQDCQEQSRRRSGSPAITENMFCAGYLDGSKDACQGDSGGPHATKFQGTWYLTGVVSWGEGCAAEGYFGVYTRVSQYIEWLRQLMVSSHTLRGLLRAPLP

Target ORF information:

RefSeq Version	XM_005634093.3
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris coagulation factor VII (F7), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005634093.3

ORF Insert Sequence:

ATGGGTCTCA CCATGGTTGC CTGGGCAGGT GAGCTGGCCC TCCTCTGCTT CCTACTGGGC 
CTGCAGGGGT CTCTGGCTGC AGGGGTGTCG GTGCTCACGG GGACCCCCCC CCAAGTCTTC 
CTCACCCAGG AGGAAGCCCA GGGTGTCCTG CACCGGCAAA GGCGCGCCAA CTCGTTCCTG 
GAGGAGCTGC GGGCCGGCTC CCTGGAGAGA GAGTGCCGGG AGGAGCAGTG CTCCTTTGAG 
GAGGCCCGGG AGATCTTCCA GGACGTGGAC AGGACGAGGC AATTCTGGAT TTCTTACAAA 
GATGGGGACC AGTGCGCCTC GAATCCATGC CAGAACGGAG GCTCCTGTGA GGACCAGCTC 
CAGTCCTACA TCTGCTTCTG CCCCGATGAC TTCCAGGGCC GGAACTGTGA GACAAATAAG 
AAGGACCAGC TGATCTGTAT GAATGAGAAT GGAGGCTGTC AGCAGTACTG CAGTGACCAC 
GCAGAGGCCA GGCGTTCCTG CTGGTGCCAC GAGGGGTACA CGCTCCAAGA CGATGGAGTG 
TCCTGCATGC CCATAGTGGA ATATCCGTGT GGAAAAATAC CTGTTCTGGA GAAGAGAATT 
GGCAGCAACC CCCAAGGCCG AATTGTGGGT GGCAAAGTGT GCCCCAAAGG GGAGTGCCCC 
TGGCAGGCGG CAGTGAAGGT GGATGGGAAG CTGCTGTGTG GGGGCACCCT GATCGACGCT 
GCCTGGGTCG TCTCTGCAGC TCACTGCTTC GAAAGAATCA AGAACTGGAA AAACCTGACG 
GTGGTGCTGG GCGAGCATGA CCTCAGTGAG GACGACGGCG ATGAGCAGGA GCGGCATGTG 
GCCCAGGTCA TCGTCCCCGA TAAGTACATT CCCCTCAAGA CGAACCATGA CATCGCCCTG 
CTGCACCTGC GCACACCCGT GGCCTACACC GACCATGTGG TGCCTCTGTG TCTGCCCGAG 
AAGACCTTCT CCGAGAGGAC GCTGGCCTTC ATCCGCTTCT CAACCGTCAG CGGCTGGGGC 
CAGCTGCTTG ACAGGGGCGC CACGGCCCTC CAGCTCATGG CCATCGACGT GCCTCGGGTG 
ATGACCCAGG ACTGCCAGGA GCAGTCCCGC AGGAGAAGTG GCTCCCCCGC CATCACTGAG 
AATATGTTCT GTGCCGGCTA CCTGGACGGG AGCAAGGACG CCTGCCAGGG GGACAGCGGG 
GGCCCGCATG CCACGAAGTT CCAGGGCACA TGGTACCTGA CAGGTGTCGT CAGCTGGGGG 
GAGGGCTGTG CGGCCGAAGG CTACTTTGGA GTGTACACCA GGGTCTCCCA GTACATCGAG 
TGGCTGCGCC AGCTCATGGT CTCCAGCCAT ACCTTGAGAG GCCTCCTCCG GGCCCCACTG 
CCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

F7 ( XM_005634094.2 ) cDNA ORF clone, Canis lupus familiaris(dog) -> XP_005634151.1 Canis lupus familiaris coagulation factor VII (serum prothrombin conversion accelerator) (F7), transcript variant X2, mRNA.

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CloneID	OCe23765
Clone ID Related Accession (Same CDS sequence)	XM_005634094.2 , XM_005634094.3
Accession Version	XM_005634094.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1167bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-09-16
Organism	Canis lupus familiaris(Dog)
Product	coagulation factor VII isoform X2
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003726099.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 17, 2015 this sequence version replaced XM_005634094.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGTCTCA CCATGGTTGC CTGGGCAGGT GAGCTGGCCC TCCTCTGCTT CCTACTGGGC 
CTGCAGGGGT CTCTGGCTGC AGATGGGGAC CAGTGCGCCT CGAATCCATG CCAGAACGGA 
GGCTCCTGTG AGGACCAGCT CCAGTCCTAC ATCTGCTTCT GCCCCGATGA CTTCCAGGGC 
CGGAACTGTG AGACAAATAA GAAGGACCAG CTGATCTGTA TGAATGAGAA TGGAGGCTGT 
CAGCAGTACT GCAGTGACCA CGCAGAGGCC AGGCGTTCCT GCTGGTGCCA CGAGGGGTAC 
ACGCTCCAAG ACGATGGAGT GTCCTGCATG CCCATAGTGG AATATCCGTG TGGAAAAATA 
CCTGTTCTGG AGAAGAGAAT TGGCAGCAAC CCCCAAGGCC GAATTGTGGG TGGCAAAGTG 
TGCCCCAAAG GGGAGTGCCC CTGGCAGGCG GCAGTGAAGG TGGATGGGAA GCTGCTGTGT 
GGGGGCACCC TGATCGACGC TGCCTGGGTC GTCTCTGCAG CTCACTGCTT CGAAAGAATC 
AAGAACTGGA AAAACCTGAC GGTGGTGCTG GGCGAGCATG ACCTCAGTGA GGACGACGGC 
GATGAGCAGG AGCGGCATGT GGCCCAGGTC ATCGTCCCCG ATAAGTACAT TCCCCTCAAG 
ACGAACCATG ACATCGCCCT GCTGCACCTG CGCACACCCG TGGCCTACAC CGACCATGTG 
GTGCCTCTGT GTCTGCCCGA GAAGACCTTC TCCGAGAGGA CGCTGGCCTT CATCCGCTTC 
TCAACCGTCA GCGGCTGGGG CCAGCTGCTT GACAGGGGCG CCACGGCCCT CCAGCTCATG 
GCCATCGACG TGCCTCGGGT GATGACCCAG GACTGCCAGG AGCAGTCCCG CAGGAGAAGT 
GGCTCCCCCG CCATCACTGA GAATATGTTC TGTGCCGGCT ACCTGGACGG GAGCAAGGAC 
GCCTGCCAGG GGGACAGCGG GGGCCCGCAT GCCACGAAGT TCCAGGGCAC ATGGTACCTG 
ACAGGTGTCG TCAGCTGGGG GGAGGGCTGT GCGGCCGAAG GCTACTTTGG AGTGTACACC 
AGGGTCTCCC AGTACATCGA GTGGCTGCGC CAGCTCATGG TCTCCAGCCA TACCTTGAGA 
GGCCTCCTCC GGGCCCCACT GCCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005634151.1
CDS	22..1188
Translation	MGLTMVAWAGELALLCFLLGLQGSLAADGDQCASNPCQNGGSCEDQLQSYICFCPDDFQGRNCETNKKDQLICMNENGGCQQYCSDHAEARRSCWCHEGYTLQDDGVSCMPIVEYPCGKIPVLEKRIGSNPQGRIVGGKVCPKGECPWQAAVKVDGKLLCGGTLIDAAWVVSAAHCFERIKNWKNLTVVLGEHDLSEDDGDEQERHVAQVIVPDKYIPLKTNHDIALLHLRTPVAYTDHVVPLCLPEKTFSERTLAFIRFSTVSGWGQLLDRGATALQLMAIDVPRVMTQDCQEQSRRRSGSPAITENMFCAGYLDGSKDACQGDSGGPHATKFQGTWYLTGVVSWGEGCAAEGYFGVYTRVSQYIEWLRQLMVSSHTLRGLLRAPLP

Target ORF information:

RefSeq Version	XM_005634094.2
Organism	Canis lupus familiaris(Dog)
Definition	Canis lupus familiaris coagulation factor VII (serum prothrombin conversion accelerator) (F7), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005634094.2

ORF Insert Sequence:

ATGGGTCTCA CCATGGTTGC CTGGGCAGGT GAGCTGGCCC TCCTCTGCTT CCTACTGGGC 
CTGCAGGGGT CTCTGGCTGC AGATGGGGAC CAGTGCGCCT CGAATCCATG CCAGAACGGA 
GGCTCCTGTG AGGACCAGCT CCAGTCCTAC ATCTGCTTCT GCCCCGATGA CTTCCAGGGC 
CGGAACTGTG AGACAAATAA GAAGGACCAG CTGATCTGTA TGAATGAGAA TGGAGGCTGT 
CAGCAGTACT GCAGTGACCA CGCAGAGGCC AGGCGTTCCT GCTGGTGCCA CGAGGGGTAC 
ACGCTCCAAG ACGATGGAGT GTCCTGCATG CCCATAGTGG AATATCCGTG TGGAAAAATA 
CCTGTTCTGG AGAAGAGAAT TGGCAGCAAC CCCCAAGGCC GAATTGTGGG TGGCAAAGTG 
TGCCCCAAAG GGGAGTGCCC CTGGCAGGCG GCAGTGAAGG TGGATGGGAA GCTGCTGTGT 
GGGGGCACCC TGATCGACGC TGCCTGGGTC GTCTCTGCAG CTCACTGCTT CGAAAGAATC 
AAGAACTGGA AAAACCTGAC GGTGGTGCTG GGCGAGCATG ACCTCAGTGA GGACGACGGC 
GATGAGCAGG AGCGGCATGT GGCCCAGGTC ATCGTCCCCG ATAAGTACAT TCCCCTCAAG 
ACGAACCATG ACATCGCCCT GCTGCACCTG CGCACACCCG TGGCCTACAC CGACCATGTG 
GTGCCTCTGT GTCTGCCCGA GAAGACCTTC TCCGAGAGGA CGCTGGCCTT CATCCGCTTC 
TCAACCGTCA GCGGCTGGGG CCAGCTGCTT GACAGGGGCG CCACGGCCCT CCAGCTCATG 
GCCATCGACG TGCCTCGGGT GATGACCCAG GACTGCCAGG AGCAGTCCCG CAGGAGAAGT 
GGCTCCCCCG CCATCACTGA GAATATGTTC TGTGCCGGCT ACCTGGACGG GAGCAAGGAC 
GCCTGCCAGG GGGACAGCGG GGGCCCGCAT GCCACGAAGT TCCAGGGCAC ATGGTACCTG 
ACAGGTGTCG TCAGCTGGGG GGAGGGCTGT GCGGCCGAAG GCTACTTTGG AGTGTACACC 
AGGGTCTCCC AGTACATCGA GTGGCTGCGC CAGCTCATGG TCTCCAGCCA TACCTTGAGA 
GGCCTCCTCC GGGCCCCACT GCCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

F7 ( XM_005634094.3 ) cDNA ORF clone, Canis lupus familiaris(dog) -> XP_005634151.1 Canis lupus familiaris coagulation factor VII (F7), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OCe23765
Clone ID Related Accession (Same CDS sequence)	XM_005634094.2 , XM_005634094.3
Accession Version	XM_005634094.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1167bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-04
Organism	Canis lupus familiaris(dog)
Product	coagulation factor VII isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006604.3) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 5, 2017 this sequence version replaced XM_005634094.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGTCTCA CCATGGTTGC CTGGGCAGGT GAGCTGGCCC TCCTCTGCTT CCTACTGGGC 
CTGCAGGGGT CTCTGGCTGC AGATGGGGAC CAGTGCGCCT CGAATCCATG CCAGAACGGA 
GGCTCCTGTG AGGACCAGCT CCAGTCCTAC ATCTGCTTCT GCCCCGATGA CTTCCAGGGC 
CGGAACTGTG AGACAAATAA GAAGGACCAG CTGATCTGTA TGAATGAGAA TGGAGGCTGT 
CAGCAGTACT GCAGTGACCA CGCAGAGGCC AGGCGTTCCT GCTGGTGCCA CGAGGGGTAC 
ACGCTCCAAG ACGATGGAGT GTCCTGCATG CCCATAGTGG AATATCCGTG TGGAAAAATA 
CCTGTTCTGG AGAAGAGAAT TGGCAGCAAC CCCCAAGGCC GAATTGTGGG TGGCAAAGTG 
TGCCCCAAAG GGGAGTGCCC CTGGCAGGCG GCAGTGAAGG TGGATGGGAA GCTGCTGTGT 
GGGGGCACCC TGATCGACGC TGCCTGGGTC GTCTCTGCAG CTCACTGCTT CGAAAGAATC 
AAGAACTGGA AAAACCTGAC GGTGGTGCTG GGCGAGCATG ACCTCAGTGA GGACGACGGC 
GATGAGCAGG AGCGGCATGT GGCCCAGGTC ATCGTCCCCG ATAAGTACAT TCCCCTCAAG 
ACGAACCATG ACATCGCCCT GCTGCACCTG CGCACACCCG TGGCCTACAC CGACCATGTG 
GTGCCTCTGT GTCTGCCCGA GAAGACCTTC TCCGAGAGGA CGCTGGCCTT CATCCGCTTC 
TCAACCGTCA GCGGCTGGGG CCAGCTGCTT GACAGGGGCG CCACGGCCCT CCAGCTCATG 
GCCATCGACG TGCCTCGGGT GATGACCCAG GACTGCCAGG AGCAGTCCCG CAGGAGAAGT 
GGCTCCCCCG CCATCACTGA GAATATGTTC TGTGCCGGCT ACCTGGACGG GAGCAAGGAC 
GCCTGCCAGG GGGACAGCGG GGGCCCGCAT GCCACGAAGT TCCAGGGCAC ATGGTACCTG 
ACAGGTGTCG TCAGCTGGGG GGAGGGCTGT GCGGCCGAAG GCTACTTTGG AGTGTACACC 
AGGGTCTCCC AGTACATCGA GTGGCTGCGC CAGCTCATGG TCTCCAGCCA TACCTTGAGA 
GGCCTCCTCC GGGCCCCACT GCCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005634151.1
CDS	41..1207
Translation	MGLTMVAWAGELALLCFLLGLQGSLAADGDQCASNPCQNGGSCEDQLQSYICFCPDDFQGRNCETNKKDQLICMNENGGCQQYCSDHAEARRSCWCHEGYTLQDDGVSCMPIVEYPCGKIPVLEKRIGSNPQGRIVGGKVCPKGECPWQAAVKVDGKLLCGGTLIDAAWVVSAAHCFERIKNWKNLTVVLGEHDLSEDDGDEQERHVAQVIVPDKYIPLKTNHDIALLHLRTPVAYTDHVVPLCLPEKTFSERTLAFIRFSTVSGWGQLLDRGATALQLMAIDVPRVMTQDCQEQSRRRSGSPAITENMFCAGYLDGSKDACQGDSGGPHATKFQGTWYLTGVVSWGEGCAAEGYFGVYTRVSQYIEWLRQLMVSSHTLRGLLRAPLP

Target ORF information:

RefSeq Version	XM_005634094.3
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris coagulation factor VII (F7), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005634094.3

ORF Insert Sequence:

ATGGGTCTCA CCATGGTTGC CTGGGCAGGT GAGCTGGCCC TCCTCTGCTT CCTACTGGGC 
CTGCAGGGGT CTCTGGCTGC AGATGGGGAC CAGTGCGCCT CGAATCCATG CCAGAACGGA 
GGCTCCTGTG AGGACCAGCT CCAGTCCTAC ATCTGCTTCT GCCCCGATGA CTTCCAGGGC 
CGGAACTGTG AGACAAATAA GAAGGACCAG CTGATCTGTA TGAATGAGAA TGGAGGCTGT 
CAGCAGTACT GCAGTGACCA CGCAGAGGCC AGGCGTTCCT GCTGGTGCCA CGAGGGGTAC 
ACGCTCCAAG ACGATGGAGT GTCCTGCATG CCCATAGTGG AATATCCGTG TGGAAAAATA 
CCTGTTCTGG AGAAGAGAAT TGGCAGCAAC CCCCAAGGCC GAATTGTGGG TGGCAAAGTG 
TGCCCCAAAG GGGAGTGCCC CTGGCAGGCG GCAGTGAAGG TGGATGGGAA GCTGCTGTGT 
GGGGGCACCC TGATCGACGC TGCCTGGGTC GTCTCTGCAG CTCACTGCTT CGAAAGAATC 
AAGAACTGGA AAAACCTGAC GGTGGTGCTG GGCGAGCATG ACCTCAGTGA GGACGACGGC 
GATGAGCAGG AGCGGCATGT GGCCCAGGTC ATCGTCCCCG ATAAGTACAT TCCCCTCAAG 
ACGAACCATG ACATCGCCCT GCTGCACCTG CGCACACCCG TGGCCTACAC CGACCATGTG 
GTGCCTCTGT GTCTGCCCGA GAAGACCTTC TCCGAGAGGA CGCTGGCCTT CATCCGCTTC 
TCAACCGTCA GCGGCTGGGG CCAGCTGCTT GACAGGGGCG CCACGGCCCT CCAGCTCATG 
GCCATCGACG TGCCTCGGGT GATGACCCAG GACTGCCAGG AGCAGTCCCG CAGGAGAAGT 
GGCTCCCCCG CCATCACTGA GAATATGTTC TGTGCCGGCT ACCTGGACGG GAGCAAGGAC 
GCCTGCCAGG GGGACAGCGG GGGCCCGCAT GCCACGAAGT TCCAGGGCAC ATGGTACCTG 
ACAGGTGTCG TCAGCTGGGG GGAGGGCTGT GCGGCCGAAG GCTACTTTGG AGTGTACACC 
AGGGTCTCCC AGTACATCGA GTGGCTGCGC CAGCTCATGG TCTCCAGCCA TACCTTGAGA 
GGCCTCCTCC GGGCCCCACT GCCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Sustained correction of FVII deficiency in dogs using AAV-mediated expression of zymogen FVII.
Blood127(5)565-71(2016 Feb)
Marcos-Contreras OA,Smith SM,Bellinger DA,Raymer RA,Merricks E,Faella A,Pavani G,Zhou S,Nichols TC,High KA,Margaritis P

Characterization of canine coagulation factor?VII and its complex formation with tissue factor: canine-human cross-species compatibility.
Journal of thrombosis and haemostasis : JTH8(8)1763-72(2010 Aug)
Knudsen T,Kristensen AT,S?rensen BB,Olsen OH,Stennicke HR,Petersen LC

Successful treatment of canine hemophilia by continuous expression of canine FVIIa.
Blood113(16)3682-9(2009 Apr)
Margaritis P,Roy E,Aljamali MN,Downey HD,Giger U,Zhou S,Merricks E,Dillow A,Ezban M,Nichols TC,High KA

A novel missense mutation responsible for factor VII deficiency in research Beagle colonies.
Journal of thrombosis and haemostasis : JTH4(12)2616-22(2006 Dec)
Callan MB,Aljamali MN,Margaritis P,Griot-Wenk ME,Pollak ES,Werner P,Giger U,High KA

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F7 cDNA ORF clone, Canis lupus familiaris(dog)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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