gRNAs
The following PKD1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PKD1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OCe00340 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001006650.1 | |
| Accession Version | NM_001006650.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 12936bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2017-10-21 | |
| Organism | Canis lupus familiaris(dog) | |
| Product | polycystin-1 precursor | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY102170.1. On Jan 18, 2005 this sequence version replaced XM_537007.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY102170.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103936001, SAMEA103936002 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGCCGCCCG CCGCGCCCGG CCGCCTGGCG CTCGCCCTGG GCCTGGGCCT GTGGCTCGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001006651.1 |
| CDS | 8..12943 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001006650.1 |
1 | ATGCCGCCCG CCGCGCCCGG CCGCCTGGCG CTCGCCCTGG GCCTGGGCCT GTGGCTCGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome-wide methylation profiling of ADPKD identified epigenetically regulated genes associated with renal cyst development. |
Hyperphosphorylation of polycystin-2 at a critical residue in disease reveals an essential role for polycystin-1-regulated dephosphorylation. |
A non-synonymous mutation in the canine Pkd1 gene is associated with autosomal dominant polycystic kidney disease in Bull Terriers. |
Analysis of the cytoplasmic interaction between polycystin-1 and polycystin-2. |
Linkage confirms canine pkd1 orthologue as a candidate for bull terrier polycystic kidney disease. |
