CYP1A2 cDNA ORF clone, Canis lupus familiaris(Dog)

Gene
Clones
gRNAs

Summary

Gene Symbol	CYP1A2
Entrez Gene ID	494010
Full Name	cytochrome P450 family 1 subfamily A member 2
Synonyms	CYPIA2,DAH2
General protein information	Preferred Names cytochrome P450 family 1 subfamily A member 2 Names cytochrome P450 1A2 Cholesterol 25-hydroxylase Cytochrome P450-D2 Cytochrome-P450-1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
Gene Type	protein-coding
Organism	Canis lupus familiaris(Dog)

mRNA and Protein(s)

mRNA	Protein	Name
XM_014109343.1	XP_013964818.1	cytochrome P450 1A2 isoform X1
NM_001008720.1	NP_001008720.1	cytochrome P450 1A2 precursor
XM_014109343.2	XP_013964818.1	cytochrome P450 1A2 isoform X1
XM_014109344.1	XP_013964819.1	cytochrome P450 1A2 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	CYP1A2	NP_000752.2
Canis lupus familiaris (dog)	CYP1A2	NP_001008720.1
Bos taurus (cattle)	CYP1A2	NP_001092834.1
Mus musculus (house mouse)	Cyp1a2	NP_034123.1
Arabidopsis thaliana (thale cress)	CYP703A2	NP_171635.1
Pan troglodytes (chimpanzee)	LOC735881	XP_001135509.2
Rattus norvegicus (Norway rat)	Cyp1a2	NP_036673.3
Oryza sativa (rice)	Os08g0131100	NP_001060927.1

Gene Ontology
Bibliography

Related articles in PubMed

Phenacetin pharmacokinetics in CYP1A2-deficient beagle dogs.
Whiterock VJ, Morgan DG, Lentz KA, Orcutt TL, Sinz MW
Drug metabolism and disposition: the biological fate of chemicals40(2)228-31(2012 Feb)

Detection of the CYP1A2 1117C>T polymorphism in 14 dog breeds.
Aretz JS, Geyer J
Journal of veterinary pharmacology and therapeutics34(1)98-100(2011 Feb)

Frequency of CYP1A2 polymorphism in beagle dogs.
Whiterock VJ, Delmonte TA, Hui LE, Orcutt TL, Sinz MW
Drug metabolism letters1(2)163-5(2007 Apr)

Elucidation of the effects of the CYP1A2 deficiency polymorphism in the metabolism of 4-cyclohexyl-1-ethyl-7-methylpyrido[2,3-d]pyrimidine-2-(1h)-one (YM-64227), a phosphodiesterase type 4 inhibitor, and its metabolites in dogs.
Tenmizu D, Noguchi K, Kamimura H
Drug metabolism and disposition: the biological fate of chemicals34(11)1811-6(2006 Nov)

Identification of the novel canine CYP1A2 1117 C > T SNP causing protein deletion.
Tenmizu D, Endo Y, Noguchi K, Kamimura H
Xenobiotica; the fate of foreign compounds in biological systems34(9)835-46(2004 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data suggest that CYP1A2 is significant enzyme responsible for formation of acetaminophen from phenacetin; however, it is not likely to be only enzyme or pathway responsible for the elimination of phenacetin or in vivo generation of acetaminophen.
Title: Phenacetin pharmacokinetics in CYP1A2-deficient beagle dogs.

a total of 508 dogs from 38 different breeds were genotyped for the CYP1A2 1117C > T polymorphism
Title: Detection of the CYP1A2 1117C>T polymorphism in 14 dog breeds.

A single nucleotide polymorphism in the dog CYP1A2 gene causes these animals to be CYP1A2 deficient (i.e., lack functional CYP1A2 enzyme activity). Genotyping a colony of 79 dogs revealed 77% wild-type, 19% heterozygous, and 4% homozygous mutant animals
Title: Frequency of CYP1A2 polymorphism in beagle dogs.

There is the interindividual variability between the pharmacokinetic profiles of the YM-64227 with respect to the CYP1A2 deficiency polymorphism.
Title: Elucidation of the effects of the CYP1A2 deficiency polymorphism in the metabolism of 4-cyclohexyl-1-ethyl-7-methylpyrido[2,3-d]pyrimidine-2-(1h)-one (YM-64227), a phosphodiesterase type 4 inhibitor, and its metabolites in dogs.

canine CYP1A2 1117 C > T SNP causes protein deletion
Title: Identification of the novel canine CYP1A2 1117 C > T SNP causing protein deletion.

The following CYP1A2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CYP1A2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OCe00410	NM_001008720.1 Latest version!	Canis lupus familiaris cytochrome P450 family 1 subfamily A member 2 (CYP1A2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00
OCe44169	XM_014109343.2 Latest version!	Canis lupus familiaris cytochrome P450, family 1, subfamily A, polypeptide 2 (CYP1A2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$342.30 $489.00
OCe44169	XM_014109344.1 Latest version!	Canis lupus familiaris cytochrome P450, family 1, subfamily A, polypeptide 2 (CYP1A2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$342.30 $489.00
View Old Accession Versions >>
OCe44169	XM_014109343.1	Canis lupus familiaris cytochrome P450, family 1, subfamily A, polypeptide 2 (CYP1A2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$342.30 $489.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CYP1A2 ( NM_001008720.1 ) cDNA ORF clone, Canis lupus familiaris(Dog) -> NP_001008720.1 Canis lupus familiaris cytochrome P450 family 1 subfamily A member 2 (CYP1A2), mRNA.

Price & Availability↑

CloneID	OCe00410
Clone ID Related Accession (Same CDS sequence)	NM_001008720.1
Accession Version	NM_001008720.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1539bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Canis lupus familiaris(dog)
Product	cytochrome P450 1A2 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB094347.1. ##Evidence-Data-START## Transcript exon combination :: AB094347.1, AB094348.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4547739, SAMEA4547740 [ECO:0000348] ##Evidence-Data-END##

ATGGCATTGT CCCAGATGGC CACAGAGCTT CTCCTGGCCT CCACCATCTT CTGCTTGGTA 
CTCTGGGTGG TCAAGGCCTG GCAGCCTCGG CTTCCCAAAG GCCTGAAGAG TCCACCGGGG 
CCCTGGGGCT GGCCCCTGCT CGGGAACGTG CTGACCTTGG GCAAGAGCCC CCACCTGGCG 
CTGTCCAGGC TGAGCCAGCG TTATGGGGAC GTGCTGCAGA TCCGCATCGG CTCCACCCCC 
GTGCTGGTGC TCAGTGGCCT GGACACCATC CGGCAGGCCC TGGTGCGCCA GGGGGATGAT 
TTCAAGGGCC GGCCCGACCT CTACAGCTTC TCTCTGGTGA CCGACGGCCA AAGCCTGACC 
TTCAGCCCAG ACTCCGGACC AGTGTGGGCT GCGCGCAGGC GCCTGGCTCA GAACGCGCTC 
AACACCTTCT CCATTGCCTC CGACCCGGCT TCCTCGTGCT CTTGCTACCT GGAAGAGCAT 
GTGAGCAAGG AGGCCGAGGC CCTTCTCAGC AGGCTGCAGG AGCAGATGGC AGAGGTTGGG 
CGCTTTGATC CCTACAACCA AGTGCTGATG TCAGTGGCCA ATGTCATTGG TGCAATGTGC 
TTTGGGCACC ACTTCTCTCA GAGAAGTGAG GAAATGCTCC CCCTCCTAAT GAGCTCCAGT 
GATTTTGTGG AGACCGTCTC CAACGGGAAC CCGGTGGACT TTTTCCCCAT TCTCCAATAT 
ATGCCCAACT CAGCCCTGCA GAGATTCAAG AACTTCAACC AGACGTTCGT GCAGTCCCTG 
CAGAAAATTG TCCAGGAACA CTATCAAGAC TTTGATGAGC GCAGTGTCCA GGACATCACA 
GGCGCCCTCT TGAAGCACAA TGAGAAGAGC TCCAGGGCTA GTGATGGCCA CATCCCCCAA 
GAGAAGATTG TCAACCTTAT CAACGACATT TTTGGGGCCG GATTTGACAC TGTCACAACG 
GCCATTTCCT GGAGTCTTAT GTACCTTGTG GCAAACCCTG AGATACAGAG AAAGATCCAG 
AAGGAGTTGG ACACGGTGAT TGGCAGGGCA CGGCAGCCTC GCCTCTCTGA CAGGCCCCAG 
CTGCCCTTAA TGGAGGCCTT CATCCTGGAG ATCTTCCGAC ACACCTCCTT TGTCCCCTTC 
ACCATCCCCC ACAGCACAAC AAAGGACACA ACCTTAAAGG GCTTCTACAT CCCCAAGGAA 
TGCTGTGTCT TCATAAACCA GTGGCAGGTC AATCATGACC AACAGGTGTG GGGGGATCCA 
TTTGCATTCC GGCCAGAGCG ATTCCTCACT GCAGATGGCA CCGCCATCAA CAAGACCTTG 
AGTGAGAAGG TGATGCTCTT TGGCATGGGC AAGCGCCGGT GCATAGGAGA GGTCCTGGCC 
AAGTGGGAGA TCTTCCTCTT CCTAGCCATC TTGCTGCAGC GGCTGGAGTT CAGCGTGCCA 
GCAGGTGTGA GAGTAGACCT AACCCCCATC TATGGGCTGA CCATGAAGCA CACCCGCTGT 
GAGCATGTCC AGGCACGGCC ACGCTTCTCC ATCAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001008720.1
CDS	63..1601
Translation	MALSQMATELLLASTIFCLVLWVVKAWQPRLPKGLKSPPGPWGWPLLGNVLTLGKSPHLALSRLSQRYGDVLQIRIGSTPVLVLSGLDTIRQALVRQGDDFKGRPDLYSFSLVTDGQSLTFSPDSGPVWAARRRLAQNALNTFSIASDPASSCSCYLEEHVSKEAEALLSRLQEQMAEVGRFDPYNQVLMSVANVIGAMCFGHHFSQRSEEMLPLLMSSSDFVETVSNGNPVDFFPILQYMPNSALQRFKNFNQTFVQSLQKIVQEHYQDFDERSVQDITGALLKHNEKSSRASDGHIPQEKIVNLINDIFGAGFDTVTTAISWSLMYLVANPEIQRKIQKELDTVIGRARQPRLSDRPQLPLMEAFILEIFRHTSFVPFTIPHSTTKDTTLKGFYIPKECCVFINQWQVNHDQQVWGDPFAFRPERFLTADGTAINKTLSEKVMLFGMGKRRCIGEVLAKWEIFLFLAILLQRLEFSVPAGVRVDLTPIYGLTMKHTRCEHVQARPRFSIK

Target ORF information:

RefSeq Version	NM_001008720.1
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris cytochrome P450 family 1 subfamily A member 2 (CYP1A2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001008720.1

ORF Insert Sequence:

ATGGCATTGT CCCAGATGGC CACAGAGCTT CTCCTGGCCT CCACCATCTT CTGCTTGGTA 
CTCTGGGTGG TCAAGGCCTG GCAGCCTCGG CTTCCCAAAG GCCTGAAGAG TCCACCGGGG 
CCCTGGGGCT GGCCCCTGCT CGGGAACGTG CTGACCTTGG GCAAGAGCCC CCACCTGGCG 
CTGTCCAGGC TGAGCCAGCG TTATGGGGAC GTGCTGCAGA TCCGCATCGG CTCCACCCCC 
GTGCTGGTGC TCAGTGGCCT GGACACCATC CGGCAGGCCC TGGTGCGCCA GGGGGATGAT 
TTCAAGGGCC GGCCCGACCT CTACAGCTTC TCTCTGGTGA CCGACGGCCA AAGCCTGACC 
TTCAGCCCAG ACTCCGGACC AGTGTGGGCT GCGCGCAGGC GCCTGGCTCA GAACGCGCTC 
AACACCTTCT CCATTGCCTC CGACCCGGCT TCCTCGTGCT CTTGCTACCT GGAAGAGCAT 
GTGAGCAAGG AGGCCGAGGC CCTTCTCAGC AGGCTGCAGG AGCAGATGGC AGAGGTTGGG 
CGCTTTGATC CCTACAACCA AGTGCTGATG TCAGTGGCCA ATGTCATTGG TGCAATGTGC 
TTTGGGCACC ACTTCTCTCA GAGAAGTGAG GAAATGCTCC CCCTCCTAAT GAGCTCCAGT 
GATTTTGTGG AGACCGTCTC CAACGGGAAC CCGGTGGACT TTTTCCCCAT TCTCCAATAT 
ATGCCCAACT CAGCCCTGCA GAGATTCAAG AACTTCAACC AGACGTTCGT GCAGTCCCTG 
CAGAAAATTG TCCAGGAACA CTATCAAGAC TTTGATGAGC GCAGTGTCCA GGACATCACA 
GGCGCCCTCT TGAAGCACAA TGAGAAGAGC TCCAGGGCTA GTGATGGCCA CATCCCCCAA 
GAGAAGATTG TCAACCTTAT CAACGACATT TTTGGGGCCG GATTTGACAC TGTCACAACG 
GCCATTTCCT GGAGTCTTAT GTACCTTGTG GCAAACCCTG AGATACAGAG AAAGATCCAG 
AAGGAGTTGG ACACGGTGAT TGGCAGGGCA CGGCAGCCTC GCCTCTCTGA CAGGCCCCAG 
CTGCCCTTAA TGGAGGCCTT CATCCTGGAG ATCTTCCGAC ACACCTCCTT TGTCCCCTTC 
ACCATCCCCC ACAGCACAAC AAAGGACACA ACCTTAAAGG GCTTCTACAT CCCCAAGGAA 
TGCTGTGTCT TCATAAACCA GTGGCAGGTC AATCATGACC AACAGGTGTG GGGGGATCCA 
TTTGCATTCC GGCCAGAGCG ATTCCTCACT GCAGATGGCA CCGCCATCAA CAAGACCTTG 
AGTGAGAAGG TGATGCTCTT TGGCATGGGC AAGCGCCGGT GCATAGGAGA GGTCCTGGCC 
AAGTGGGAGA TCTTCCTCTT CCTAGCCATC TTGCTGCAGC GGCTGGAGTT CAGCGTGCCA 
GCAGGTGTGA GAGTAGACCT AACCCCCATC TATGGGCTGA CCATGAAGCA CACCCGCTGT 
GAGCATGTCC AGGCACGGCC ACGCTTCTCC ATCAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CYP1A2 ( XM_014109343.1 ) cDNA ORF clone, Canis lupus familiaris(Dog) -> XP_013964818.1 Canis lupus familiaris cytochrome P450, family 1, subfamily A, polypeptide 2 (CYP1A2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OCe44169
Clone ID Related Accession (Same CDS sequence)	XM_014109343.1 , XM_014109343.2 , XM_014109344.1
Accession Version	XM_014109343.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1554bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-09-16
Organism	Canis lupus familiaris(Dog)
Product	cytochrome P450 1A2 isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003726113.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCATTGT CCCAGATGGC CACAGAGCTT CTCCTGGCCT CCACCATCTT CTGCTTGGTA 
CTCTGGGTGG TCAAGGCCTG GCAGCCTCGG CTTCCCAAAG GCCTGAAGAG TCCACCGGGG 
CCCTGGGGCT GGCCCCTGCT TGGGAACGTG CTGACCTTGG GCAAGAGCCC CCACCTGGCG 
CTGTCCAGGC TGAGCCAGCG TTATGGGGAC GTGCTGCAGA TCCGCATCGG CTCCACCCCC 
GTGCTGGTGC TCAGCAGCCT GGACACCATC CGGCAGGCCC TGGTGCGCCA GGGGGATGAT 
TTCAAGGGCC GGCCCGACCT CTACAGCTTC TCTCTGGTGA CCGACGGCCA AAGCCTGACC 
TTCAGCCCAG ACTCCGGACC AGTGTGGGCT GCGCGCAGGC GCCTGGCTCA GAACGCGCTC 
AACACCTTCT CCATTGCCTC CGACCCGGCT TCCTCGTGCT CTTGCTACCT GGAAGAGCAT 
GTGAGCAAGG AGGCCGAGGC CCTTCTCAGC AGGCTGCAGG AGCAGATGGC AGAGGTTGGG 
CGCTTTGATC CCTACAACCA TGTGCTGCTG TCAGTGGCCA ATGTCATTGG TGCAATGTGC 
TTTGGGCACC ACTTCTCTCA GAGAAGTGAG GAAATGCTCC CCCTCCTAAT GAGCTCCAGT 
GATTTTGTGG AGACCGTCTC CAACGGGAAC CCGGTGGACT TTTTCCCCAT TCTCCAATAT 
ATGCCCAACT CAGCCCTGCA GAGATTCAAG AACTTCAACC AGACGTTCGT GCAGTCCCTG 
CAGAAAATTG TCCAGGAACA CTATCAAGAC TTTGATGAGC TTGTGTCCCC ACAGCGCAGT 
GTCCAGGACA TCACAGGCGC CCTCTTGAAG CACAATGAGA AGAGCTCCAG GGCTAGTGAT 
GGCCACATCC CCCAAGAGAA GATTGTCAAC CTTATCAACG ACATTTTTGG GGCCGGATTT 
GACACTGTCA CAACGGCCAT TTCCTGGAGT CTTATGTACC TTGTGGCAAA CCCTGAGATA 
CAGAGAAAGA TCCAGAAGGA GTTGGACACG GTGATTGGCA GGGCACGGCA GCCTCGCCTC 
TCTGACAGGC CCCAGCTGCC CTTAATGGAG GCCTTCATCC TGGAGATCTT CCGACACACC 
TCCTTTGTCC CCTTCACCAT CCCCCACAGC ACAACAAAGA ACACAACGTT AAAGGGCTTC 
TACATCCCCA AGGAATGCTG TGTCTTCATA AACCAGTGGC AGGTCAATCA TGACCAACAG 
GTGTGGGGGG ATCCATTTGC ATTCCGGCCA GAGCGATTCC TCACTGCAGA TGGCACCGCC 
ATCAACAAGA CCTTGAGTGA GAAGGTGATG CTCTTTGGCA TGGGCAAGCG CCGGTGCATA 
GGAGAGGTCC TGGCCAAGTG GGAGATCTTC CTCTTCCTAG CCATCTTGCT GCAGCGGCTG 
GAGTTCAGCG TGCCAGCAGG TGTGAGAGTA GACCTAACCC CCATCTATGG GCTGACCATG 
AAGCACACCC GCTGTGAGCA TGTCCAGGCA CGGCCACGCT TCTCCATCAA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_013964818.1
CDS	86..1639
Translation	MALSQMATELLLASTIFCLVLWVVKAWQPRLPKGLKSPPGPWGWPLLGNVLTLGKSPHLALSRLSQRYGDVLQIRIGSTPVLVLSSLDTIRQALVRQGDDFKGRPDLYSFSLVTDGQSLTFSPDSGPVWAARRRLAQNALNTFSIASDPASSCSCYLEEHVSKEAEALLSRLQEQMAEVGRFDPYNHVLLSVANVIGAMCFGHHFSQRSEEMLPLLMSSSDFVETVSNGNPVDFFPILQYMPNSALQRFKNFNQTFVQSLQKIVQEHYQDFDELVSPQRSVQDITGALLKHNEKSSRASDGHIPQEKIVNLINDIFGAGFDTVTTAISWSLMYLVANPEIQRKIQKELDTVIGRARQPRLSDRPQLPLMEAFILEIFRHTSFVPFTIPHSTTKNTTLKGFYIPKECCVFINQWQVNHDQQVWGDPFAFRPERFLTADGTAINKTLSEKVMLFGMGKRRCIGEVLAKWEIFLFLAILLQRLEFSVPAGVRVDLTPIYGLTMKHTRCEHVQARPRFSIK

Target ORF information:

RefSeq Version	XM_014109343.1
Organism	Canis lupus familiaris(Dog)
Definition	Canis lupus familiaris cytochrome P450, family 1, subfamily A, polypeptide 2 (CYP1A2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_014109343.1

ORF Insert Sequence:

ATGGCATTGT CCCAGATGGC CACAGAGCTT CTCCTGGCCT CCACCATCTT CTGCTTGGTA 
CTCTGGGTGG TCAAGGCCTG GCAGCCTCGG CTTCCCAAAG GCCTGAAGAG TCCACCGGGG 
CCCTGGGGCT GGCCCCTGCT TGGGAACGTG CTGACCTTGG GCAAGAGCCC CCACCTGGCG 
CTGTCCAGGC TGAGCCAGCG TTATGGGGAC GTGCTGCAGA TCCGCATCGG CTCCACCCCC 
GTGCTGGTGC TCAGCAGCCT GGACACCATC CGGCAGGCCC TGGTGCGCCA GGGGGATGAT 
TTCAAGGGCC GGCCCGACCT CTACAGCTTC TCTCTGGTGA CCGACGGCCA AAGCCTGACC 
TTCAGCCCAG ACTCCGGACC AGTGTGGGCT GCGCGCAGGC GCCTGGCTCA GAACGCGCTC 
AACACCTTCT CCATTGCCTC CGACCCGGCT TCCTCGTGCT CTTGCTACCT GGAAGAGCAT 
GTGAGCAAGG AGGCCGAGGC CCTTCTCAGC AGGCTGCAGG AGCAGATGGC AGAGGTTGGG 
CGCTTTGATC CCTACAACCA TGTGCTGCTG TCAGTGGCCA ATGTCATTGG TGCAATGTGC 
TTTGGGCACC ACTTCTCTCA GAGAAGTGAG GAAATGCTCC CCCTCCTAAT GAGCTCCAGT 
GATTTTGTGG AGACCGTCTC CAACGGGAAC CCGGTGGACT TTTTCCCCAT TCTCCAATAT 
ATGCCCAACT CAGCCCTGCA GAGATTCAAG AACTTCAACC AGACGTTCGT GCAGTCCCTG 
CAGAAAATTG TCCAGGAACA CTATCAAGAC TTTGATGAGC TTGTGTCCCC ACAGCGCAGT 
GTCCAGGACA TCACAGGCGC CCTCTTGAAG CACAATGAGA AGAGCTCCAG GGCTAGTGAT 
GGCCACATCC CCCAAGAGAA GATTGTCAAC CTTATCAACG ACATTTTTGG GGCCGGATTT 
GACACTGTCA CAACGGCCAT TTCCTGGAGT CTTATGTACC TTGTGGCAAA CCCTGAGATA 
CAGAGAAAGA TCCAGAAGGA GTTGGACACG GTGATTGGCA GGGCACGGCA GCCTCGCCTC 
TCTGACAGGC CCCAGCTGCC CTTAATGGAG GCCTTCATCC TGGAGATCTT CCGACACACC 
TCCTTTGTCC CCTTCACCAT CCCCCACAGC ACAACAAAGA ACACAACGTT AAAGGGCTTC 
TACATCCCCA AGGAATGCTG TGTCTTCATA AACCAGTGGC AGGTCAATCA TGACCAACAG 
GTGTGGGGGG ATCCATTTGC ATTCCGGCCA GAGCGATTCC TCACTGCAGA TGGCACCGCC 
ATCAACAAGA CCTTGAGTGA GAAGGTGATG CTCTTTGGCA TGGGCAAGCG CCGGTGCATA 
GGAGAGGTCC TGGCCAAGTG GGAGATCTTC CTCTTCCTAG CCATCTTGCT GCAGCGGCTG 
GAGTTCAGCG TGCCAGCAGG TGTGAGAGTA GACCTAACCC CCATCTATGG GCTGACCATG 
AAGCACACCC GCTGTGAGCA TGTCCAGGCA CGGCCACGCT TCTCCATCAA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CYP1A2 ( XM_014109343.2 ) cDNA ORF clone, Canis lupus familiaris(Dog) -> XP_013964818.1 Canis lupus familiaris cytochrome P450, family 1, subfamily A, polypeptide 2 (CYP1A2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OCe44169
Clone ID Related Accession (Same CDS sequence)	XM_014109343.1 , XM_014109343.2 , XM_014109344.1
Accession Version	XM_014109343.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1554bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-04
Organism	Canis lupus familiaris(dog)
Product	cytochrome P450 1A2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006612.3) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 5, 2017 this sequence version replaced XM_014109343.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCATTGT CCCAGATGGC CACAGAGCTT CTCCTGGCCT CCACCATCTT CTGCTTGGTA 
CTCTGGGTGG TCAAGGCCTG GCAGCCTCGG CTTCCCAAAG GCCTGAAGAG TCCACCGGGG 
CCCTGGGGCT GGCCCCTGCT TGGGAACGTG CTGACCTTGG GCAAGAGCCC CCACCTGGCG 
CTGTCCAGGC TGAGCCAGCG TTATGGGGAC GTGCTGCAGA TCCGCATCGG CTCCACCCCC 
GTGCTGGTGC TCAGCAGCCT GGACACCATC CGGCAGGCCC TGGTGCGCCA GGGGGATGAT 
TTCAAGGGCC GGCCCGACCT CTACAGCTTC TCTCTGGTGA CCGACGGCCA AAGCCTGACC 
TTCAGCCCAG ACTCCGGACC AGTGTGGGCT GCGCGCAGGC GCCTGGCTCA GAACGCGCTC 
AACACCTTCT CCATTGCCTC CGACCCGGCT TCCTCGTGCT CTTGCTACCT GGAAGAGCAT 
GTGAGCAAGG AGGCCGAGGC CCTTCTCAGC AGGCTGCAGG AGCAGATGGC AGAGGTTGGG 
CGCTTTGATC CCTACAACCA TGTGCTGCTG TCAGTGGCCA ATGTCATTGG TGCAATGTGC 
TTTGGGCACC ACTTCTCTCA GAGAAGTGAG GAAATGCTCC CCCTCCTAAT GAGCTCCAGT 
GATTTTGTGG AGACCGTCTC CAACGGGAAC CCGGTGGACT TTTTCCCCAT TCTCCAATAT 
ATGCCCAACT CAGCCCTGCA GAGATTCAAG AACTTCAACC AGACGTTCGT GCAGTCCCTG 
CAGAAAATTG TCCAGGAACA CTATCAAGAC TTTGATGAGC TTGTGTCCCC ACAGCGCAGT 
GTCCAGGACA TCACAGGCGC CCTCTTGAAG CACAATGAGA AGAGCTCCAG GGCTAGTGAT 
GGCCACATCC CCCAAGAGAA GATTGTCAAC CTTATCAACG ACATTTTTGG GGCCGGATTT 
GACACTGTCA CAACGGCCAT TTCCTGGAGT CTTATGTACC TTGTGGCAAA CCCTGAGATA 
CAGAGAAAGA TCCAGAAGGA GTTGGACACG GTGATTGGCA GGGCACGGCA GCCTCGCCTC 
TCTGACAGGC CCCAGCTGCC CTTAATGGAG GCCTTCATCC TGGAGATCTT CCGACACACC 
TCCTTTGTCC CCTTCACCAT CCCCCACAGC ACAACAAAGA ACACAACGTT AAAGGGCTTC 
TACATCCCCA AGGAATGCTG TGTCTTCATA AACCAGTGGC AGGTCAATCA TGACCAACAG 
GTGTGGGGGG ATCCATTTGC ATTCCGGCCA GAGCGATTCC TCACTGCAGA TGGCACCGCC 
ATCAACAAGA CCTTGAGTGA GAAGGTGATG CTCTTTGGCA TGGGCAAGCG CCGGTGCATA 
GGAGAGGTCC TGGCCAAGTG GGAGATCTTC CTCTTCCTAG CCATCTTGCT GCAGCGGCTG 
GAGTTCAGCG TGCCAGCAGG TGTGAGAGTA GACCTAACCC CCATCTATGG GCTGACCATG 
AAGCACACCC GCTGTGAGCA TGTCCAGGCA CGGCCACGCT TCTCCATCAA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_013964818.1
CDS	111..1664
Translation	MALSQMATELLLASTIFCLVLWVVKAWQPRLPKGLKSPPGPWGWPLLGNVLTLGKSPHLALSRLSQRYGDVLQIRIGSTPVLVLSSLDTIRQALVRQGDDFKGRPDLYSFSLVTDGQSLTFSPDSGPVWAARRRLAQNALNTFSIASDPASSCSCYLEEHVSKEAEALLSRLQEQMAEVGRFDPYNHVLLSVANVIGAMCFGHHFSQRSEEMLPLLMSSSDFVETVSNGNPVDFFPILQYMPNSALQRFKNFNQTFVQSLQKIVQEHYQDFDELVSPQRSVQDITGALLKHNEKSSRASDGHIPQEKIVNLINDIFGAGFDTVTTAISWSLMYLVANPEIQRKIQKELDTVIGRARQPRLSDRPQLPLMEAFILEIFRHTSFVPFTIPHSTTKNTTLKGFYIPKECCVFINQWQVNHDQQVWGDPFAFRPERFLTADGTAINKTLSEKVMLFGMGKRRCIGEVLAKWEIFLFLAILLQRLEFSVPAGVRVDLTPIYGLTMKHTRCEHVQARPRFSIK

Target ORF information:

RefSeq Version	XM_014109343.2
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris cytochrome P450, family 1, subfamily A, polypeptide 2 (CYP1A2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_014109343.2

ORF Insert Sequence:

ATGGCATTGT CCCAGATGGC CACAGAGCTT CTCCTGGCCT CCACCATCTT CTGCTTGGTA 
CTCTGGGTGG TCAAGGCCTG GCAGCCTCGG CTTCCCAAAG GCCTGAAGAG TCCACCGGGG 
CCCTGGGGCT GGCCCCTGCT TGGGAACGTG CTGACCTTGG GCAAGAGCCC CCACCTGGCG 
CTGTCCAGGC TGAGCCAGCG TTATGGGGAC GTGCTGCAGA TCCGCATCGG CTCCACCCCC 
GTGCTGGTGC TCAGCAGCCT GGACACCATC CGGCAGGCCC TGGTGCGCCA GGGGGATGAT 
TTCAAGGGCC GGCCCGACCT CTACAGCTTC TCTCTGGTGA CCGACGGCCA AAGCCTGACC 
TTCAGCCCAG ACTCCGGACC AGTGTGGGCT GCGCGCAGGC GCCTGGCTCA GAACGCGCTC 
AACACCTTCT CCATTGCCTC CGACCCGGCT TCCTCGTGCT CTTGCTACCT GGAAGAGCAT 
GTGAGCAAGG AGGCCGAGGC CCTTCTCAGC AGGCTGCAGG AGCAGATGGC AGAGGTTGGG 
CGCTTTGATC CCTACAACCA TGTGCTGCTG TCAGTGGCCA ATGTCATTGG TGCAATGTGC 
TTTGGGCACC ACTTCTCTCA GAGAAGTGAG GAAATGCTCC CCCTCCTAAT GAGCTCCAGT 
GATTTTGTGG AGACCGTCTC CAACGGGAAC CCGGTGGACT TTTTCCCCAT TCTCCAATAT 
ATGCCCAACT CAGCCCTGCA GAGATTCAAG AACTTCAACC AGACGTTCGT GCAGTCCCTG 
CAGAAAATTG TCCAGGAACA CTATCAAGAC TTTGATGAGC TTGTGTCCCC ACAGCGCAGT 
GTCCAGGACA TCACAGGCGC CCTCTTGAAG CACAATGAGA AGAGCTCCAG GGCTAGTGAT 
GGCCACATCC CCCAAGAGAA GATTGTCAAC CTTATCAACG ACATTTTTGG GGCCGGATTT 
GACACTGTCA CAACGGCCAT TTCCTGGAGT CTTATGTACC TTGTGGCAAA CCCTGAGATA 
CAGAGAAAGA TCCAGAAGGA GTTGGACACG GTGATTGGCA GGGCACGGCA GCCTCGCCTC 
TCTGACAGGC CCCAGCTGCC CTTAATGGAG GCCTTCATCC TGGAGATCTT CCGACACACC 
TCCTTTGTCC CCTTCACCAT CCCCCACAGC ACAACAAAGA ACACAACGTT AAAGGGCTTC 
TACATCCCCA AGGAATGCTG TGTCTTCATA AACCAGTGGC AGGTCAATCA TGACCAACAG 
GTGTGGGGGG ATCCATTTGC ATTCCGGCCA GAGCGATTCC TCACTGCAGA TGGCACCGCC 
ATCAACAAGA CCTTGAGTGA GAAGGTGATG CTCTTTGGCA TGGGCAAGCG CCGGTGCATA 
GGAGAGGTCC TGGCCAAGTG GGAGATCTTC CTCTTCCTAG CCATCTTGCT GCAGCGGCTG 
GAGTTCAGCG TGCCAGCAGG TGTGAGAGTA GACCTAACCC CCATCTATGG GCTGACCATG 
AAGCACACCC GCTGTGAGCA TGTCCAGGCA CGGCCACGCT TCTCCATCAA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CYP1A2 ( XM_014109344.1 ) cDNA ORF clone, Canis lupus familiaris(Dog) -> XP_013964819.1 Canis lupus familiaris cytochrome P450, family 1, subfamily A, polypeptide 2 (CYP1A2), transcript variant X2, mRNA.

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CloneID	OCe44169
Clone ID Related Accession (Same CDS sequence)	XM_014109343.1 , XM_014109343.2 , XM_014109344.1
Accession Version	XM_014109344.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1554bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-09-16
Organism	Canis lupus familiaris(Dog)
Product	cytochrome P450 1A2 isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003726113.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCATTGT CCCAGATGGC CACAGAGCTT CTCCTGGCCT CCACCATCTT CTGCTTGGTA 
CTCTGGGTGG TCAAGGCCTG GCAGCCTCGG CTTCCCAAAG GCCTGAAGAG TCCACCGGGG 
CCCTGGGGCT GGCCCCTGCT TGGGAACGTG CTGACCTTGG GCAAGAGCCC CCACCTGGCG 
CTGTCCAGGC TGAGCCAGCG TTATGGGGAC GTGCTGCAGA TCCGCATCGG CTCCACCCCC 
GTGCTGGTGC TCAGCAGCCT GGACACCATC CGGCAGGCCC TGGTGCGCCA GGGGGATGAT 
TTCAAGGGCC GGCCCGACCT CTACAGCTTC TCTCTGGTGA CCGACGGCCA AAGCCTGACC 
TTCAGCCCAG ACTCCGGACC AGTGTGGGCT GCGCGCAGGC GCCTGGCTCA GAACGCGCTC 
AACACCTTCT CCATTGCCTC CGACCCGGCT TCCTCGTGCT CTTGCTACCT GGAAGAGCAT 
GTGAGCAAGG AGGCCGAGGC CCTTCTCAGC AGGCTGCAGG AGCAGATGGC AGAGGTTGGG 
CGCTTTGATC CCTACAACCA TGTGCTGCTG TCAGTGGCCA ATGTCATTGG TGCAATGTGC 
TTTGGGCACC ACTTCTCTCA GAGAAGTGAG GAAATGCTCC CCCTCCTAAT GAGCTCCAGT 
GATTTTGTGG AGACCGTCTC CAACGGGAAC CCGGTGGACT TTTTCCCCAT TCTCCAATAT 
ATGCCCAACT CAGCCCTGCA GAGATTCAAG AACTTCAACC AGACGTTCGT GCAGTCCCTG 
CAGAAAATTG TCCAGGAACA CTATCAAGAC TTTGATGAGC TTGTGTCCCC ACAGCGCAGT 
GTCCAGGACA TCACAGGCGC CCTCTTGAAG CACAATGAGA AGAGCTCCAG GGCTAGTGAT 
GGCCACATCC CCCAAGAGAA GATTGTCAAC CTTATCAACG ACATTTTTGG GGCCGGATTT 
GACACTGTCA CAACGGCCAT TTCCTGGAGT CTTATGTACC TTGTGGCAAA CCCTGAGATA 
CAGAGAAAGA TCCAGAAGGA GTTGGACACG GTGATTGGCA GGGCACGGCA GCCTCGCCTC 
TCTGACAGGC CCCAGCTGCC CTTAATGGAG GCCTTCATCC TGGAGATCTT CCGACACACC 
TCCTTTGTCC CCTTCACCAT CCCCCACAGC ACAACAAAGA ACACAACGTT AAAGGGCTTC 
TACATCCCCA AGGAATGCTG TGTCTTCATA AACCAGTGGC AGGTCAATCA TGACCAACAG 
GTGTGGGGGG ATCCATTTGC ATTCCGGCCA GAGCGATTCC TCACTGCAGA TGGCACCGCC 
ATCAACAAGA CCTTGAGTGA GAAGGTGATG CTCTTTGGCA TGGGCAAGCG CCGGTGCATA 
GGAGAGGTCC TGGCCAAGTG GGAGATCTTC CTCTTCCTAG CCATCTTGCT GCAGCGGCTG 
GAGTTCAGCG TGCCAGCAGG TGTGAGAGTA GACCTAACCC CCATCTATGG GCTGACCATG 
AAGCACACCC GCTGTGAGCA TGTCCAGGCA CGGCCACGCT TCTCCATCAA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_013964819.1
CDS	57..1610
Translation	MALSQMATELLLASTIFCLVLWVVKAWQPRLPKGLKSPPGPWGWPLLGNVLTLGKSPHLALSRLSQRYGDVLQIRIGSTPVLVLSSLDTIRQALVRQGDDFKGRPDLYSFSLVTDGQSLTFSPDSGPVWAARRRLAQNALNTFSIASDPASSCSCYLEEHVSKEAEALLSRLQEQMAEVGRFDPYNHVLLSVANVIGAMCFGHHFSQRSEEMLPLLMSSSDFVETVSNGNPVDFFPILQYMPNSALQRFKNFNQTFVQSLQKIVQEHYQDFDELVSPQRSVQDITGALLKHNEKSSRASDGHIPQEKIVNLINDIFGAGFDTVTTAISWSLMYLVANPEIQRKIQKELDTVIGRARQPRLSDRPQLPLMEAFILEIFRHTSFVPFTIPHSTTKNTTLKGFYIPKECCVFINQWQVNHDQQVWGDPFAFRPERFLTADGTAINKTLSEKVMLFGMGKRRCIGEVLAKWEIFLFLAILLQRLEFSVPAGVRVDLTPIYGLTMKHTRCEHVQARPRFSIK

Target ORF information:

RefSeq Version	XM_014109344.1
Organism	Canis lupus familiaris(Dog)
Definition	Canis lupus familiaris cytochrome P450, family 1, subfamily A, polypeptide 2 (CYP1A2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_014109344.1

ORF Insert Sequence:

ATGGCATTGT CCCAGATGGC CACAGAGCTT CTCCTGGCCT CCACCATCTT CTGCTTGGTA 
CTCTGGGTGG TCAAGGCCTG GCAGCCTCGG CTTCCCAAAG GCCTGAAGAG TCCACCGGGG 
CCCTGGGGCT GGCCCCTGCT TGGGAACGTG CTGACCTTGG GCAAGAGCCC CCACCTGGCG 
CTGTCCAGGC TGAGCCAGCG TTATGGGGAC GTGCTGCAGA TCCGCATCGG CTCCACCCCC 
GTGCTGGTGC TCAGCAGCCT GGACACCATC CGGCAGGCCC TGGTGCGCCA GGGGGATGAT 
TTCAAGGGCC GGCCCGACCT CTACAGCTTC TCTCTGGTGA CCGACGGCCA AAGCCTGACC 
TTCAGCCCAG ACTCCGGACC AGTGTGGGCT GCGCGCAGGC GCCTGGCTCA GAACGCGCTC 
AACACCTTCT CCATTGCCTC CGACCCGGCT TCCTCGTGCT CTTGCTACCT GGAAGAGCAT 
GTGAGCAAGG AGGCCGAGGC CCTTCTCAGC AGGCTGCAGG AGCAGATGGC AGAGGTTGGG 
CGCTTTGATC CCTACAACCA TGTGCTGCTG TCAGTGGCCA ATGTCATTGG TGCAATGTGC 
TTTGGGCACC ACTTCTCTCA GAGAAGTGAG GAAATGCTCC CCCTCCTAAT GAGCTCCAGT 
GATTTTGTGG AGACCGTCTC CAACGGGAAC CCGGTGGACT TTTTCCCCAT TCTCCAATAT 
ATGCCCAACT CAGCCCTGCA GAGATTCAAG AACTTCAACC AGACGTTCGT GCAGTCCCTG 
CAGAAAATTG TCCAGGAACA CTATCAAGAC TTTGATGAGC TTGTGTCCCC ACAGCGCAGT 
GTCCAGGACA TCACAGGCGC CCTCTTGAAG CACAATGAGA AGAGCTCCAG GGCTAGTGAT 
GGCCACATCC CCCAAGAGAA GATTGTCAAC CTTATCAACG ACATTTTTGG GGCCGGATTT 
GACACTGTCA CAACGGCCAT TTCCTGGAGT CTTATGTACC TTGTGGCAAA CCCTGAGATA 
CAGAGAAAGA TCCAGAAGGA GTTGGACACG GTGATTGGCA GGGCACGGCA GCCTCGCCTC 
TCTGACAGGC CCCAGCTGCC CTTAATGGAG GCCTTCATCC TGGAGATCTT CCGACACACC 
TCCTTTGTCC CCTTCACCAT CCCCCACAGC ACAACAAAGA ACACAACGTT AAAGGGCTTC 
TACATCCCCA AGGAATGCTG TGTCTTCATA AACCAGTGGC AGGTCAATCA TGACCAACAG 
GTGTGGGGGG ATCCATTTGC ATTCCGGCCA GAGCGATTCC TCACTGCAGA TGGCACCGCC 
ATCAACAAGA CCTTGAGTGA GAAGGTGATG CTCTTTGGCA TGGGCAAGCG CCGGTGCATA 
GGAGAGGTCC TGGCCAAGTG GGAGATCTTC CTCTTCCTAG CCATCTTGCT GCAGCGGCTG 
GAGTTCAGCG TGCCAGCAGG TGTGAGAGTA GACCTAACCC CCATCTATGG GCTGACCATG 
AAGCACACCC GCTGTGAGCA TGTCCAGGCA CGGCCACGCT TCTCCATCAA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Phenacetin pharmacokinetics in CYP1A2-deficient beagle dogs.
Drug metabolism and disposition: the biological fate of chemicals40(2)228-31(2012 Feb)
Whiterock VJ,Morgan DG,Lentz KA,Orcutt TL,Sinz MW

Detection of the CYP1A2 1117C>T polymorphism in 14 dog breeds.
Journal of veterinary pharmacology and therapeutics34(1)98-100(2011 Feb)
Aretz JS,Geyer J

Frequency of CYP1A2 polymorphism in beagle dogs.
Drug metabolism letters1(2)163-5(2007 Apr)
Whiterock VJ,Delmonte TA,Hui LE,Orcutt TL,Sinz MW

Elucidation of the effects of the CYP1A2 deficiency polymorphism in the metabolism of 4-cyclohexyl-1-ethyl-7-methylpyrido[2,3-d]pyrimidine-2-(1h)-one (YM-64227), a phosphodiesterase type 4 inhibitor, and its metabolites in dogs.
Drug metabolism and disposition: the biological fate of chemicals34(11)1811-6(2006 Nov)
Tenmizu D,Noguchi K,Kamimura H

Identification of the novel canine CYP1A2 1117 C > T SNP causing protein deletion.
Xenobiotica; the fate of foreign compounds in biological systems34(9)835-46(2004 Sep)
Tenmizu D,Endo Y,Noguchi K,Kamimura H

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CYP1A2 cDNA ORF clone, Canis lupus familiaris(Dog)

Gene

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gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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