SLC5A1 cDNA ORF clone, Canis lupus familiaris(dog)

Gene
Clones
gRNAs

Summary

Gene Symbol	SLC5A1
Entrez Gene ID	492299
Full Name	solute carrier family 5 member 1
Synonyms	SGLT1
Gene Type	protein-coding
Organism	Canis lupus familiaris(dog)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001007141.1	NP_001007142.1	sodium/glucose cotransporter 1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	SLC5A1	NP_001007142.1
Xenopus tropicalis (tropical clawed frog)	LOC100498135	XP_002931963.2
Pan troglodytes (chimpanzee)	SLC5A1	XP_515093.3
Mus musculus (house mouse)	Slc5a1	NP_062784.3
Danio rerio (zebrafish)	slc5a1	NP_956975.1
	SLC5A1	XP_001112212.1
Rattus norvegicus (Norway rat)	Slc5a1	NP_037165.1
Xenopus tropicalis (tropical clawed frog)	LOC100493915	XP_004910646.1
Homo sapiens (human)	SLC5A1	NP_000334.1
Bos taurus (cattle)	SLC5A1	NP_777031.1
Gallus gallus (chicken)	SLC5A1	XP_415247.3

Gene Ontology
Bibliography

Related articles in PubMed

Relevance of sodium/glucose cotransporter-1 (SGLT1) to diabetes mellitus and obesity in dogs.
Batchelor DJ, German AJ, Shirazi-Beechey SP
Domestic animal endocrinology44(3)139-44(2013 Apr)

Sodium/glucose cotransporter-1, sweet receptor, and disaccharidase expression in the intestine of the domestic dog and cat: two species of different dietary habit.
Batchelor DJ, Al-Rammahi M, Moran AW, Brand JG, Li X, Haskins M, German AJ, Shirazi-Beechey SP
American journal of physiology. Regulatory, integrative and comparative physiology300(1)R67-75(2011 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Variations in Slc5a1 promoter sequence between dogs do not influence the pathogenesis of diabetes mellitus or obesity in these breeds.
Title: Relevance of sodium/glucose cotransporter-1 (SGLT1) to diabetes mellitus and obesity in dogs.

SGLT1 function in dogs was 1.9- to 2.3-fold higher than in cats.
Title: Sodium/glucose cotransporter-1, sweet receptor, and disaccharidase expression in the intestine of the domestic dog and cat: two species of different dietary habit.

The following SLC5A1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SLC5A1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OCe33807	NM_001007141.1 Latest version!	Canis lupus familiaris solute carrier family 5 member 1 (SLC5A1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SLC5A1 ( NM_001007141.1 ) cDNA ORF clone, Canis lupus familiaris(dog) -> NP_001007142.1 Canis lupus familiaris solute carrier family 5 member 1 (SLC5A1), mRNA.

Price & Availability↑

CloneID	OCe33807
Clone ID Related Accession (Same CDS sequence)	NM_001007141.1
Accession Version	NM_001007141.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1989bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-02-24
Organism	Canis lupus familiaris(dog)
Product	sodium/glucose cotransporter 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY772536.1. On Jan 18, 2005 this sequence version replaced XM_543496.1. ##Evidence-Data-START## Transcript exon combination :: AY772536.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00991610, SAMN00991611 [ECO:0000348] ##Evidence-Data-END##

ATGGACAGTA CCACCTGGAG CCCCATGACC AACGCCACTG CCTCACCCCT CGCGCCCCAC 
GAGCGCATCC GCAATGCCGC CGACATCTCT GTCATCGTCA TCTACTTTGT GGTGGTGATG 
GCTGTGGGGC TGTGGGCTAT GTTTTCCACT AATCGTGGGA CTGTTGGAGG CTTCTTCTTG 
GCAGGACGGA GTATGGTGTG GTGGCCGGTT GGAGCATCTC TCTTTGCCAG TAACATTGGG 
AGTGGCCACT TTGTGGGGCT GGCGGGGACA GGAGCTGCTG CAGGCATTGC CATGGGAGGC 
TTTGAATGGA ATGCCTTGAT TTGGGTAGTT GTCTTGGGCT GGGTGTTTGT TCCCATTTAC 
ATTAAGGCTG GGGTGGTGAC AATGCCAGAG TACCTGAGGA AGCGATTTGG AGGCAAGCGA 
ATCCAGATCT ACCTCTCTAT TCTGTCCCTG TTACTCTACA TTTTCACTAA GATCTCGGCA 
GATATCTTCT CTGGGGCCAT ATTTATCAAC ATGGCCTTGG GTCTTGATCT TTACCTGGCC 
ATCTTTATCT TATTGGCAAT CACTGGCCTT TACACAATCA CAGGGGGCCT GGCAGCTGTG 
ATTTACACAG ACACTTTGCA GACGGCCATC ATGCTGGTGG GGTCTCTTAT CCTGACTGGG 
TTTGCTTTTC ACGAAGTGGG AGGGTATGAT GCCTTCATGA CAAAGTACAT GAACGCCCTT 
CCAACTGTGG TTACTGATGG AAACTTCACC GTTAAGGAAG AATGCTATAC ACCAAGAGCT 
GACTCTTTTC ACATTTTCCG AGATCCCATC AGTGGAGATC TGCCATGGCC TGGGCTCATC 
TTTGGGTTGT CCATCCTTGC CCTGTGGTAT TGGTGCACAG ATCAGGTCAT TGTGCAACGC 
TGCCTCTCAG CCAAAAACAT GTCTCATGTG AAGGCCGGCT GTATCCTGTG TGGGTACATG 
AAGCTGCTAC CCATGTTCCT TATGGTGATG CCAGGGATGA TCAGCCGCAT TCTGTACACA 
GAAAAAGTTG CCTGCACCGT CCCCTCGGAA TGTAAGAAAT ATTGTGGTAC TGAGGTTGGC 
TGTACCAACA TCGCTTACCC GACTTTGGTG GTGGAGCTCA TGCCTGATGG ACTGCGAGGT 
CTGATGCTGT CAGTCATGTT GGCCTCTCTC ATGAGCTCCT TAACCTCCAT CTTCAATAGT 
GCCAGTACCC TCTTCACCAT GGACATCTAC ACCAAGGTCC GAAAGGGAGC ATCTGAGAAA 
GAGCTTATGA TTGCAGGAAG GTTGTTCATC CTGGTGCTGA TAGGTATCAG CATTGCCTGG 
GTACCCATTG TGCAGTCAGC ACAAAGTGGG CAGCTCTTCG ATTACATCCA GTCCATTACC 
AGTTACTTGG GACCACCCAT TGCAGCTGTC TTCCTGCTTG CTATTTTCTG CAAGAGAGTC 
AATGAGCAGG GAGCCTTTTG GGGACTGATC ATAGGATTTC TGATTGGGGT GTCCCGTATG 
GTGACTGAAT TTGCCTATGG AACTGGGAGC TGCATGCAGC CCAGCAACTG TCCCACGATT 
ATCTGTGGAG TGCACTACCT ATACTTTGCC ATCATCCTCT TTGTCATTTC TGTCGTCATC 
ATCCTGGTTG TCTCTCTCTT CACCAAGCCA ATTCCAGATG TGCATCTCTA CCGCCTGTGT 
TGGAGCCTAC GCAACAGCAA AGAGGAGCGT ATTGACTTGG ATGCTGGAGA AGAGGACATC 
CAAGAAACCC CAGAGGAGAC CCTTGATATA GAAGTTCCTG AGGAGAAAAA AGGATGCTTC 
AGGCGTGCCT ATGACCTATT CTGTGGCCTG GACCAGCAGA AGGGCCCCAA GATGACAAAG 
GAAGAGGAGG AAGCTATGAA GCTGAAGATG ACAGACACCT CAGAGAAACC TTTCTGGCGA 
ACAGTAGTGA ACATTAATGG CATCATCCTG CTGTCTGTGG CAGTTTTCTG CCATGCATTT 
TTTGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001007142.1
CDS	1..1989
Translation	MDSTTWSPMTNATASPLAPHERIRNAADISVIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPVGASLFASNIGSGHFVGLAGTGAAAGIAMGGFEWNALIWVVVLGWVFVPIYIKAGVVTMPEYLRKRFGGKRIQIYLSILSLLLYIFTKISADIFSGAIFINMALGLDLYLAIFILLAITGLYTITGGLAAVIYTDTLQTAIMLVGSLILTGFAFHEVGGYDAFMTKYMNALPTVVTDGNFTVKEECYTPRADSFHIFRDPISGDLPWPGLIFGLSILALWYWCTDQVIVQRCLSAKNMSHVKAGCILCGYMKLLPMFLMVMPGMISRILYTEKVACTVPSECKKYCGTEVGCTNIAYPTLVVELMPDGLRGLMLSVMLASLMSSLTSIFNSASTLFTMDIYTKVRKGASEKELMIAGRLFILVLIGISIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFCKRVNEQGAFWGLIIGFLIGVSRMVTEFAYGTGSCMQPSNCPTIICGVHYLYFAIILFVISVVIILVVSLFTKPIPDVHLYRLCWSLRNSKEERIDLDAGEEDIQETPEETLDIEVPEEKKGCFRRAYDLFCGLDQQKGPKMTKEEEEAMKLKMTDTSEKPFWRTVVNINGIILLSVAVFCHAFFA

Target ORF information:

RefSeq Version	NM_001007141.1
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris solute carrier family 5 member 1 (SLC5A1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001007141.1

ORF Insert Sequence:

ATGGACAGTA CCACCTGGAG CCCCATGACC AACGCCACTG CCTCACCCCT CGCGCCCCAC 
GAGCGCATCC GCAATGCCGC CGACATCTCT GTCATCGTCA TCTACTTTGT GGTGGTGATG 
GCTGTGGGGC TGTGGGCTAT GTTTTCCACT AATCGTGGGA CTGTTGGAGG CTTCTTCTTG 
GCAGGACGGA GTATGGTGTG GTGGCCGGTT GGAGCATCTC TCTTTGCCAG TAACATTGGG 
AGTGGCCACT TTGTGGGGCT GGCGGGGACA GGAGCTGCTG CAGGCATTGC CATGGGAGGC 
TTTGAATGGA ATGCCTTGAT TTGGGTAGTT GTCTTGGGCT GGGTGTTTGT TCCCATTTAC 
ATTAAGGCTG GGGTGGTGAC AATGCCAGAG TACCTGAGGA AGCGATTTGG AGGCAAGCGA 
ATCCAGATCT ACCTCTCTAT TCTGTCCCTG TTACTCTACA TTTTCACTAA GATCTCGGCA 
GATATCTTCT CTGGGGCCAT ATTTATCAAC ATGGCCTTGG GTCTTGATCT TTACCTGGCC 
ATCTTTATCT TATTGGCAAT CACTGGCCTT TACACAATCA CAGGGGGCCT GGCAGCTGTG 
ATTTACACAG ACACTTTGCA GACGGCCATC ATGCTGGTGG GGTCTCTTAT CCTGACTGGG 
TTTGCTTTTC ACGAAGTGGG AGGGTATGAT GCCTTCATGA CAAAGTACAT GAACGCCCTT 
CCAACTGTGG TTACTGATGG AAACTTCACC GTTAAGGAAG AATGCTATAC ACCAAGAGCT 
GACTCTTTTC ACATTTTCCG AGATCCCATC AGTGGAGATC TGCCATGGCC TGGGCTCATC 
TTTGGGTTGT CCATCCTTGC CCTGTGGTAT TGGTGCACAG ATCAGGTCAT TGTGCAACGC 
TGCCTCTCAG CCAAAAACAT GTCTCATGTG AAGGCCGGCT GTATCCTGTG TGGGTACATG 
AAGCTGCTAC CCATGTTCCT TATGGTGATG CCAGGGATGA TCAGCCGCAT TCTGTACACA 
GAAAAAGTTG CCTGCACCGT CCCCTCGGAA TGTAAGAAAT ATTGTGGTAC TGAGGTTGGC 
TGTACCAACA TCGCTTACCC GACTTTGGTG GTGGAGCTCA TGCCTGATGG ACTGCGAGGT 
CTGATGCTGT CAGTCATGTT GGCCTCTCTC ATGAGCTCCT TAACCTCCAT CTTCAATAGT 
GCCAGTACCC TCTTCACCAT GGACATCTAC ACCAAGGTCC GAAAGGGAGC ATCTGAGAAA 
GAGCTTATGA TTGCAGGAAG GTTGTTCATC CTGGTGCTGA TAGGTATCAG CATTGCCTGG 
GTACCCATTG TGCAGTCAGC ACAAAGTGGG CAGCTCTTCG ATTACATCCA GTCCATTACC 
AGTTACTTGG GACCACCCAT TGCAGCTGTC TTCCTGCTTG CTATTTTCTG CAAGAGAGTC 
AATGAGCAGG GAGCCTTTTG GGGACTGATC ATAGGATTTC TGATTGGGGT GTCCCGTATG 
GTGACTGAAT TTGCCTATGG AACTGGGAGC TGCATGCAGC CCAGCAACTG TCCCACGATT 
ATCTGTGGAG TGCACTACCT ATACTTTGCC ATCATCCTCT TTGTCATTTC TGTCGTCATC 
ATCCTGGTTG TCTCTCTCTT CACCAAGCCA ATTCCAGATG TGCATCTCTA CCGCCTGTGT 
TGGAGCCTAC GCAACAGCAA AGAGGAGCGT ATTGACTTGG ATGCTGGAGA AGAGGACATC 
CAAGAAACCC CAGAGGAGAC CCTTGATATA GAAGTTCCTG AGGAGAAAAA AGGATGCTTC 
AGGCGTGCCT ATGACCTATT CTGTGGCCTG GACCAGCAGA AGGGCCCCAA GATGACAAAG 
GAAGAGGAGG AAGCTATGAA GCTGAAGATG ACAGACACCT CAGAGAAACC TTTCTGGCGA 
ACAGTAGTGA ACATTAATGG CATCATCCTG CTGTCTGTGG CAGTTTTCTG CCATGCATTT 
TTTGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Relevance of sodium/glucose cotransporter-1 (SGLT1) to diabetes mellitus and obesity in dogs.
Domestic animal endocrinology44(3)139-44(2013 Apr)
Batchelor DJ,German AJ,Shirazi-Beechey SP

Sodium/glucose cotransporter-1, sweet receptor, and disaccharidase expression in the intestine of the domestic dog and cat: two species of different dietary habit.
American journal of physiology. Regulatory, integrative and comparative physiology300(1)R67-75(2011 Jan)
Batchelor DJ,Al-Rammahi M,Moran AW,Brand JG,Li X,Haskins M,German AJ,Shirazi-Beechey SP

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SLC5A1 cDNA ORF clone, Canis lupus familiaris(dog)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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