Gene Symbol | EDA |
Entrez Gene ID | 491935 |
Full Name | ectodysplasin A |
Synonyms | TNLG7C |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(Dog) |
ORF » Species Summary » Canis lupus familiaris » EDA cDNA ORF clone
Gene Symbol | EDA |
Entrez Gene ID | 491935 |
Full Name | ectodysplasin A |
Synonyms | TNLG7C |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(Dog) |
mRNA | Protein | Name |
---|---|---|
XM_014111340.1 | XP_013966815.1 | ectodysplasin-A isoform X4 |
XM_022415518.1 | XP_022271226.1 | ectodysplasin-A isoform X1 |
XM_005641018.2 | XP_005641075.1 | ectodysplasin-A isoform X3 |
XM_005641019.1 | XP_005641076.1 | ectodysplasin-A isoform X3 |
XM_005641017.2 | XP_005641074.1 | ectodysplasin-A isoform X2 |
XM_005641019.2 | XP_005641076.1 | ectodysplasin-A isoform X4 |
XM_005641018.1 | XP_005641075.1 | ectodysplasin-A isoform X2 |
NM_001014770.2 | NP_001014770.1 | ectodysplasin-A |
XM_005641017.1 | XP_005641074.1 | ectodysplasin-A isoform X1 |
A Splice Defect in the EDA Gene in Dogs with an X-Linked Hypohidrotic Ectodermal Dysplasia (XLHED) Phenotype.
Waluk DP, Zur G, Kaufmann R, Welle MM, Jagannathan V, Dr?gem?ller C, M?ller EJ, Leeb T, Galichet A
G3 (Bethesda, Md.)6(9)2949-54(2016 09)
Comparative genomic analysis of eutherian tumor necrosis factor ligand genes.
Premzl M
Immunogenetics68(2)125-32(2016 Feb)
Mutation identification in a canine model of X-linked ectodermal dysplasia.
Casal ML, Scheidt JL, Rhodes JL, Henthorn PS, Werner P
Mammalian genome : official journal of the International Mammalian Genome Society16(7)524-31(2005 Jul)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The altered EDA transcript splicing most likely causes the observed ectodermal dysplasia in the affected dogs. These dogs thus offer an excellent opportunity to gain insights into the complex splicing processes required for expression of the EDA gene, and other genes with large introns.
Title: A Splice Defect in the EDA Gene in Dogs with an X-Linked Hypohidrotic Ectodermal Dysplasia (XLHED) Phenotype.
A frameshift mutation, with premature stop codon in the EDA gene results in the absence of its receptor-binding site, causing X-linked hypohidrotic ectodermal dysplasia.
Title: Mutation identification in a canine model of X-linked ectodermal dysplasia.
The following EDA gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the EDA cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCe33635 | |
Clone ID Related Accession (Same CDS sequence) | NM_001014770.2 | |
Accession Version | NM_001014770.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1161bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-05-06 | |
Organism | Canis lupus familiaris(dog) | |
Product | ectodysplasin-A | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AAEX03026473.1, AAEX03026476.1 and AAEX03026477.1. On Apr 13, 2016 this sequence version replaced NM_001014770.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA103936001, SAMEA4547742 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGGCTACC CAGAGGTAGA GCGCCGGGAA CCTCTGCCCA CAGCAGCGCC GCGGGAGCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001014770.1 |
CDS | 224..1384 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001014770.2 |
1 | ATGGGCTACC CAGAGGTAGA GCGCCGGGAA CCTCTGCCCA CAGCAGCGCC GCGGGAGCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCe285077 | |
Clone ID Related Accession (Same CDS sequence) | XM_022415518.1 | |
Accession Version | XM_022415518.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1158bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-09-04 | |
Organism | Canis lupus familiaris(dog) | |
Product | ectodysplasin-A isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006621.3) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGCTACC CAGAGGTAGA GCGCCGGGAA CCTCTGCCCA CAGCAGCGCC GCGGGAGCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_022271226.1 |
CDS | 273..1430 |
Translation |
Target ORF information:
Target ORF information:
|
XM_022415518.1 |
1 | ATGGGCTACC CAGAGGTAGA GCGCCGGGAA CCTCTGCCCA CAGCAGCGCC GCGGGAGCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCe31962 | |
Clone ID Related Accession (Same CDS sequence) | XM_005641017.2 , XM_005641017.1 | |
Accession Version | XM_005641017.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1155bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-09-04 | |
Organism | Canis lupus familiaris(dog) | |
Product | ectodysplasin-A isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006621.3) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Sep 5, 2017 this sequence version replaced XM_005641017.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGCTACC CAGAGGTAGA GCGCCGGGAA CCTCTGCCCA CAGCAGCGCC GCGGGAGCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005641074.1 |
CDS | 273..1427 |
Translation |
Target ORF information:
Target ORF information:
|
XM_005641017.2 |
1 | ATGGGCTACC CAGAGGTAGA GCGCCGGGAA CCTCTGCCCA CAGCAGCGCC GCGGGAGCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCe31962 | |
Clone ID Related Accession (Same CDS sequence) | XM_005641017.2 , XM_005641017.1 | |
Accession Version | XM_005641017.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1155bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-09-16 | |
Organism | Canis lupus familiaris(Dog) | |
Product | ectodysplasin-A isoform X1 | |
Comment | MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003726126.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGCTACC CAGAGGTAGA GCGCCGGGAA CCTCTGCCCA CAGCAGCGCC GCGGGAGCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005641074.1 |
CDS | 224..1378 |
Translation |
Target ORF information:
Target ORF information:
|
XM_005641017.1 |
1 | ATGGGCTACC CAGAGGTAGA GCGCCGGGAA CCTCTGCCCA CAGCAGCGCC GCGGGAGCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCe31963 | |
Clone ID Related Accession (Same CDS sequence) | XM_005641018.2 , XM_005641018.1 | |
Accession Version | XM_005641018.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1152bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-09-04 | |
Organism | Canis lupus familiaris(dog) | |
Product | ectodysplasin-A isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006621.3) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 5, 2017 this sequence version replaced XM_005641018.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGCTACC CAGAGGTAGA GCGCCGGGAA CCTCTGCCCA CAGCAGCGCC GCGGGAGCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005641075.1 |
CDS | 273..1424 |
Translation |
Target ORF information:
Target ORF information:
|
XM_005641018.2 |
1 | ATGGGCTACC CAGAGGTAGA GCGCCGGGAA CCTCTGCCCA CAGCAGCGCC GCGGGAGCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCe31963 | |
Clone ID Related Accession (Same CDS sequence) | XM_005641018.2 , XM_005641018.1 | |
Accession Version | XM_005641018.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1152bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-09-16 | |
Organism | Canis lupus familiaris(Dog) | |
Product | ectodysplasin-A isoform X2 | |
Comment | MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003726126.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGCTACC CAGAGGTAGA GCGCCGGGAA CCTCTGCCCA CAGCAGCGCC GCGGGAGCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005641075.1 |
CDS | 224..1375 |
Translation |
Target ORF information:
Target ORF information:
|
XM_005641018.1 |
1 | ATGGGCTACC CAGAGGTAGA GCGCCGGGAA CCTCTGCCCA CAGCAGCGCC GCGGGAGCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCe31964 | |
Clone ID Related Accession (Same CDS sequence) | XM_005641019.1 , XM_005641019.2 | |
Accession Version | XM_005641019.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1146bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-09-16 | |
Organism | Canis lupus familiaris(Dog) | |
Product | ectodysplasin-A isoform X3 | |
Comment | MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003726126.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGCTACC CAGAGGTAGA GCGCCGGGAA CCTCTGCCCA CAGCAGCGCC GCGGGAGCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005641076.1 |
CDS | 224..1369 |
Translation |
Target ORF information:
Target ORF information:
|
XM_005641019.1 |
1 | ATGGGCTACC CAGAGGTAGA GCGCCGGGAA CCTCTGCCCA CAGCAGCGCC GCGGGAGCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCe31964 | |
Clone ID Related Accession (Same CDS sequence) | XM_005641019.1 , XM_005641019.2 | |
Accession Version | XM_005641019.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1146bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-09-04 | |
Organism | Canis lupus familiaris(dog) | |
Product | ectodysplasin-A isoform X4 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006621.3) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 5, 2017 this sequence version replaced XM_005641019.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGCTACC CAGAGGTAGA GCGCCGGGAA CCTCTGCCCA CAGCAGCGCC GCGGGAGCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005641076.1 |
CDS | 273..1418 |
Translation |
Target ORF information:
Target ORF information:
|
XM_005641019.2 |
1 | ATGGGCTACC CAGAGGTAGA GCGCCGGGAA CCTCTGCCCA CAGCAGCGCC GCGGGAGCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCe45412 | |
Clone ID Related Accession (Same CDS sequence) | XM_014111340.1 | |
Accession Version | XM_014111340.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1119bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-09-16 | |
Organism | Canis lupus familiaris(Dog) | |
Product | ectodysplasin-A isoform X4 | |
Comment | MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003726126.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGCTACC CAGAGGTAGA GCGCCGGGAA CCTCTGCCCA CAGCAGCGCC GCGGGAGCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_013966815.1 |
CDS | 224..1342 |
Translation |
Target ORF information:
Target ORF information:
|
XM_014111340.1 |
1 | ATGGGCTACC CAGAGGTAGA GCGCCGGGAA CCTCTGCCCA CAGCAGCGCC GCGGGAGCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
A Splice Defect in the EDA Gene in Dogs with an X-Linked Hypohidrotic Ectodermal Dysplasia (XLHED) Phenotype. |
Comparative genomic analysis of eutherian tumor necrosis factor ligand genes. |
Mutation identification in a canine model of X-linked ectodermal dysplasia. |