GJC1 cDNA ORF clone, Canis lupus familiaris(dog)

Gene
Clones
gRNAs

Summary

Gene Symbol	GJC1
Entrez Gene ID	490936
Full Name	gap junction protein gamma 1
Synonyms	CX45,GJA7
General protein information	Preferred Names gap junction protein gamma 1 Names gap junction gamma-1 protein connexin 45 gap junction alpha-7 protein gap junction protein, alpha 7, 45kDa (connexin 45) gap junction protein, delta 3, 31.9kDa
Gene Type	protein-coding
Organism	Canis lupus familiaris(dog)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001020812.2	NP_001018648.1	gap junction gamma-1 protein
XM_005624343.3	XP_005624400.1	gap junction gamma-1 protein isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	GJC1	XP_511557.1
	GJC1	XP_001114752.1
Mus musculus (house mouse)	Gjc1	NP_032148.1
Canis lupus familiaris (dog)	GJC1	NP_001018648.1
Rattus norvegicus (Norway rat)	Gjc1	NP_001078850.1
Danio rerio (zebrafish)	LOC564307	XP_005163904.1
Xenopus tropicalis (tropical clawed frog)	gjc1	XP_002935609.1
Homo sapiens (human)	GJC1	NP_001073852.1
Gallus gallus (chicken)	GJC1	NP_990834.1
Bos taurus (cattle)	GJC1	NP_001039541.1

Gene Ontology
Bibliography

Related articles in PubMed

[Association between myocardial connexin 40 and 45 expression and myocardial fibrosis in the rapid atrial pacing canine model].
Xing XQ, Xu J, Su H, Lu YW
Zhonghua xin xue guan bing za zhi39(2)176-80(2011 Feb)

The keeshond defect in cardiac conotruncal development is oligogenic.
Werner P, Raducha MG, Prociuk U, Ostrander EA, Spielman RS, Kirkness EF, Patterson DF, Henthorn PS
Human genetics116(5)368-77(2005 Apr)

Distinct gap junction protein phenotypes in cardiac tissues with disparate conduction properties.
Davis LM, Kanter HL, Beyer EC, Saffitz JE
Journal of the American College of Cardiology24(4)1124-32(1994 Oct)

Cardiac myocytes express multiple gap junction proteins.
Kanter HL, Saffitz JE, Beyer EC
Circulation research70(2)438-44(1992 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

There was no change of Cx45 expression in left atrium in rapid atrial paced canines.
Title: [Association between myocardial connexin 40 and 45 expression and myocardial fibrosis in the rapid atrial pacing canine model].

The following GJC1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GJC1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OCe11480	NM_001020812.2 Latest version!	Canis lupus familiaris gap junction protein gamma 1 (GJC1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OCe11480	XM_005624343.3 Latest version!	Canis lupus familiaris gap junction protein gamma 1 (GJC1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

GJC1 ( NM_001020812.2 ) cDNA ORF clone, Canis lupus familiaris(dog) -> NP_001018648.1 Canis lupus familiaris gap junction protein gamma 1 (GJC1), mRNA.

Price & Availability↑

CloneID	OCe11480
Clone ID Related Accession (Same CDS sequence)	NM_001020812.2 , XM_005624343.3
Accession Version	NM_001020812.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1191bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-28
Organism	Canis lupus familiaris(dog)
Product	gap junction gamma-1 protein
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AAEX03006411.1. On Sep 2, 2015 this sequence version replaced NM_001020812.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.

ATGAGTTGGA GCTTCCTGAC TCGCCTGCTA GAGGAGATCC ACAACCATTC CACATTTGTG 
GGGAAGATCT GGCTCACTGT ATTGATTGTC TTTCGGATTG TCCTTACAGC TGTAGGAGGG 
GAGTCCATCT ATTACGATGA GCAAAGCAAA TTTGTATGTA ACACAGAGCA GCCAGGCTGT 
GAAAATGTCT GCTATGATGC TTTTGCACCC CTCTCCCACG TGCGCTTCTG GGTATTCCAG 
ATCATCCTGG TGGCAACCCC CTCAGTGATG TACCTGGGTT ATGCCATTCA TAAGATTGCC 
AAAATGGAGC ATGGAGAAGC AGACAAGAAG GCAGCTCGGA GCAAACCGTA TGCAATGCGT 
TGGAAACAGC ACCGGGCTCT TGAAGAAACA GAAGAGGACC ATGAAGAGGA TCCCATGATG 
TATCCAGAAA TGGAATTGGA AAGTGAAAAA GAAAATAAGG AGCAGAACCA ACCTAAACCC 
AAGCATGATG GCCGACGGCG GATTCGGGAG GATGGGCTTA TGAAAATCTA CGTGCTGCAG 
TTGCTTGCAA GGACCGTATT TGAGGTGGGT TTTCTGATAG GGCAGTATTT TCTGTATGGC 
TTCCAAGTCC ACCCATTTTA TGTGTGCAGC AGACTTCCTT GCCCTCATAA AATAGACTGC 
TTTATTTCTA GACCTACTGA AAAGACCATC TTCCTTCTAA TAATGTATGG TGTTACAGGC 
CTTTGCCTGT TGCTTAACAT TTGGGAAATG CTTCATTTAG GGTTTGGGAC AATTCGAGAC 
TCACTAAACA GTAAAAGGAG GGAACTGGAA GATCCGGGTG CTTATAATTA TCCTTTCACT 
TGGAATACAC CATCTGCTCC CCCTGGCTAT AACATTGCCG TCAAACCAGA TCAGATCCAG 
TACACCGAAC TGTCCAATGC TAAGATTGCC TACAAGCAAA ACAAGGCCAA CATCGCCCAG 
GAACAACAGT ATGGCAGCCA CGAGGAGAAT CTCCCCGCTG ACCTGGAGAC TCTGCAGCGG 
GAGATTAAAA TGGCTCAGGA ACGCTTGGAT CTAGCAATCC AGGCCTACAG TCACCAAAAC 
AACCCCCACG GACCCCGGGA AAAAAAAGCC AAAGTGGGGT CCAAAGCTGG GTCCAACAAG 
AGCAGTGCTA GTAGCAAATC AGGAGATGGG AAGACCTCCG TCTGGATTTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001018648.1
CDS	1..1191
Translation	MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGCENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMRWKQHRALEETEEDHEEDPMMYPEMELESEKENKEQNQPKPKHDGRRRIREDGLMKIYVLQLLARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVTGLCLLLNIWEMLHLGFGTIRDSLNSKRRELEDPGAYNYPFTWNTPSAPPGYNIAVKPDQIQYTELSNAKIAYKQNKANIAQEQQYGSHEENLPADLETLQREIKMAQERLDLAIQAYSHQNNPHGPREKKAKVGSKAGSNKSSASSKSGDGKTSVWI

Target ORF information:

RefSeq Version	NM_001020812.2
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris gap junction protein gamma 1 (GJC1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001020812.2

ORF Insert Sequence:

ATGAGTTGGA GCTTCCTGAC TCGCCTGCTA GAGGAGATCC ACAACCATTC CACATTTGTG 
GGGAAGATCT GGCTCACTGT ATTGATTGTC TTTCGGATTG TCCTTACAGC TGTAGGAGGG 
GAGTCCATCT ATTACGATGA GCAAAGCAAA TTTGTATGTA ACACAGAGCA GCCAGGCTGT 
GAAAATGTCT GCTATGATGC TTTTGCACCC CTCTCCCACG TGCGCTTCTG GGTATTCCAG 
ATCATCCTGG TGGCAACCCC CTCAGTGATG TACCTGGGTT ATGCCATTCA TAAGATTGCC 
AAAATGGAGC ATGGAGAAGC AGACAAGAAG GCAGCTCGGA GCAAACCGTA TGCAATGCGT 
TGGAAACAGC ACCGGGCTCT TGAAGAAACA GAAGAGGACC ATGAAGAGGA TCCCATGATG 
TATCCAGAAA TGGAATTGGA AAGTGAAAAA GAAAATAAGG AGCAGAACCA ACCTAAACCC 
AAGCATGATG GCCGACGGCG GATTCGGGAG GATGGGCTTA TGAAAATCTA CGTGCTGCAG 
TTGCTTGCAA GGACCGTATT TGAGGTGGGT TTTCTGATAG GGCAGTATTT TCTGTATGGC 
TTCCAAGTCC ACCCATTTTA TGTGTGCAGC AGACTTCCTT GCCCTCATAA AATAGACTGC 
TTTATTTCTA GACCTACTGA AAAGACCATC TTCCTTCTAA TAATGTATGG TGTTACAGGC 
CTTTGCCTGT TGCTTAACAT TTGGGAAATG CTTCATTTAG GGTTTGGGAC AATTCGAGAC 
TCACTAAACA GTAAAAGGAG GGAACTGGAA GATCCGGGTG CTTATAATTA TCCTTTCACT 
TGGAATACAC CATCTGCTCC CCCTGGCTAT AACATTGCCG TCAAACCAGA TCAGATCCAG 
TACACCGAAC TGTCCAATGC TAAGATTGCC TACAAGCAAA ACAAGGCCAA CATCGCCCAG 
GAACAACAGT ATGGCAGCCA CGAGGAGAAT CTCCCCGCTG ACCTGGAGAC TCTGCAGCGG 
GAGATTAAAA TGGCTCAGGA ACGCTTGGAT CTAGCAATCC AGGCCTACAG TCACCAAAAC 
AACCCCCACG GACCCCGGGA AAAAAAAGCC AAAGTGGGGT CCAAAGCTGG GTCCAACAAG 
AGCAGTGCTA GTAGCAAATC AGGAGATGGG AAGACCTCCG TCTGGATTTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GJC1 ( XM_005624343.3 ) cDNA ORF clone, Canis lupus familiaris(dog) -> XP_005624400.1 Canis lupus familiaris gap junction protein gamma 1 (GJC1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OCe11480
Clone ID Related Accession (Same CDS sequence)	NM_001020812.2 , XM_005624343.3
Accession Version	XM_005624343.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1191bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-04
Organism	Canis lupus familiaris(dog)
Product	gap junction gamma-1 protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006591.3) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Sep 5, 2017 this sequence version replaced XM_005624343.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGTTGGA GCTTCCTGAC TCGCCTGCTA GAGGAGATCC ACAACCATTC CACATTTGTG 
GGGAAGATCT GGCTCACTGT ATTGATTGTC TTTCGGATTG TCCTTACAGC TGTAGGAGGG 
GAGTCCATCT ATTACGATGA GCAAAGCAAA TTTGTATGTA ACACAGAGCA GCCAGGCTGT 
GAAAATGTCT GCTATGATGC TTTTGCACCC CTCTCCCACG TGCGCTTCTG GGTATTCCAG 
ATCATCCTGG TGGCAACCCC CTCAGTGATG TACCTGGGTT ATGCCATTCA TAAGATTGCC 
AAAATGGAGC ATGGAGAAGC AGACAAGAAG GCAGCTCGGA GCAAACCGTA TGCAATGCGT 
TGGAAACAGC ACCGGGCTCT TGAAGAAACA GAAGAGGACC ATGAAGAGGA TCCCATGATG 
TATCCAGAAA TGGAATTGGA AAGTGAAAAA GAAAATAAGG AGCAGAACCA ACCTAAACCC 
AAGCATGATG GCCGACGGCG GATTCGGGAG GATGGGCTTA TGAAAATCTA CGTGCTGCAG 
TTGCTTGCAA GGACCGTATT TGAGGTGGGT TTTCTGATAG GGCAGTATTT TCTGTATGGC 
TTCCAAGTCC ACCCATTTTA TGTGTGCAGC AGACTTCCTT GCCCTCATAA AATAGACTGC 
TTTATTTCTA GACCTACTGA AAAGACCATC TTCCTTCTAA TAATGTATGG TGTTACAGGC 
CTTTGCCTGT TGCTTAACAT TTGGGAAATG CTTCATTTAG GGTTTGGGAC AATTCGAGAC 
TCACTAAACA GTAAAAGGAG GGAACTGGAA GATCCGGGTG CTTATAATTA TCCTTTCACT 
TGGAATACAC CATCTGCTCC CCCTGGCTAT AACATTGCCG TCAAACCAGA TCAGATCCAG 
TACACCGAAC TGTCCAATGC TAAGATTGCC TACAAGCAAA ACAAGGCCAA CATCGCCCAG 
GAACAACAGT ATGGCAGCCA CGAGGAGAAT CTCCCCGCTG ACCTGGAGAC TCTGCAGCGG 
GAGATTAAAA TGGCTCAGGA ACGCTTGGAT CTAGCAATCC AGGCCTACAG TCACCAAAAC 
AACCCCCACG GACCCCGGGA AAAAAAAGCC AAAGTGGGGT CCAAAGCTGG GTCCAACAAG 
AGCAGTGCTA GTAGCAAATC AGGAGATGGG AAGACCTCCG TCTGGATTTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005624400.1
CDS	273..1463
Translation	MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGCENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMRWKQHRALEETEEDHEEDPMMYPEMELESEKENKEQNQPKPKHDGRRRIREDGLMKIYVLQLLARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVTGLCLLLNIWEMLHLGFGTIRDSLNSKRRELEDPGAYNYPFTWNTPSAPPGYNIAVKPDQIQYTELSNAKIAYKQNKANIAQEQQYGSHEENLPADLETLQREIKMAQERLDLAIQAYSHQNNPHGPREKKAKVGSKAGSNKSSASSKSGDGKTSVWI

Target ORF information:

RefSeq Version	XM_005624343.3
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris gap junction protein gamma 1 (GJC1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005624343.3

ORF Insert Sequence:

ATGAGTTGGA GCTTCCTGAC TCGCCTGCTA GAGGAGATCC ACAACCATTC CACATTTGTG 
GGGAAGATCT GGCTCACTGT ATTGATTGTC TTTCGGATTG TCCTTACAGC TGTAGGAGGG 
GAGTCCATCT ATTACGATGA GCAAAGCAAA TTTGTATGTA ACACAGAGCA GCCAGGCTGT 
GAAAATGTCT GCTATGATGC TTTTGCACCC CTCTCCCACG TGCGCTTCTG GGTATTCCAG 
ATCATCCTGG TGGCAACCCC CTCAGTGATG TACCTGGGTT ATGCCATTCA TAAGATTGCC 
AAAATGGAGC ATGGAGAAGC AGACAAGAAG GCAGCTCGGA GCAAACCGTA TGCAATGCGT 
TGGAAACAGC ACCGGGCTCT TGAAGAAACA GAAGAGGACC ATGAAGAGGA TCCCATGATG 
TATCCAGAAA TGGAATTGGA AAGTGAAAAA GAAAATAAGG AGCAGAACCA ACCTAAACCC 
AAGCATGATG GCCGACGGCG GATTCGGGAG GATGGGCTTA TGAAAATCTA CGTGCTGCAG 
TTGCTTGCAA GGACCGTATT TGAGGTGGGT TTTCTGATAG GGCAGTATTT TCTGTATGGC 
TTCCAAGTCC ACCCATTTTA TGTGTGCAGC AGACTTCCTT GCCCTCATAA AATAGACTGC 
TTTATTTCTA GACCTACTGA AAAGACCATC TTCCTTCTAA TAATGTATGG TGTTACAGGC 
CTTTGCCTGT TGCTTAACAT TTGGGAAATG CTTCATTTAG GGTTTGGGAC AATTCGAGAC 
TCACTAAACA GTAAAAGGAG GGAACTGGAA GATCCGGGTG CTTATAATTA TCCTTTCACT 
TGGAATACAC CATCTGCTCC CCCTGGCTAT AACATTGCCG TCAAACCAGA TCAGATCCAG 
TACACCGAAC TGTCCAATGC TAAGATTGCC TACAAGCAAA ACAAGGCCAA CATCGCCCAG 
GAACAACAGT ATGGCAGCCA CGAGGAGAAT CTCCCCGCTG ACCTGGAGAC TCTGCAGCGG 
GAGATTAAAA TGGCTCAGGA ACGCTTGGAT CTAGCAATCC AGGCCTACAG TCACCAAAAC 
AACCCCCACG GACCCCGGGA AAAAAAAGCC AAAGTGGGGT CCAAAGCTGG GTCCAACAAG 
AGCAGTGCTA GTAGCAAATC AGGAGATGGG AAGACCTCCG TCTGGATTTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

[Association between myocardial connexin 40 and 45 expression and myocardial fibrosis in the rapid atrial pacing canine model].
Zhonghua xin xue guan bing za zhi39(2)176-80(2011 Feb)
Xing XQ,Xu J,Su H,Lu YW

The keeshond defect in cardiac conotruncal development is oligogenic.
Human genetics116(5)368-77(2005 Apr)
Werner P,Raducha MG,Prociuk U,Ostrander EA,Spielman RS,Kirkness EF,Patterson DF,Henthorn PS

Distinct gap junction protein phenotypes in cardiac tissues with disparate conduction properties.
Journal of the American College of Cardiology24(4)1124-32(1994 Oct)
Davis LM,Kanter HL,Beyer EC,Saffitz JE

Cardiac myocytes express multiple gap junction proteins.
Circulation research70(2)438-44(1992 Feb)
Kanter HL,Saffitz JE,Beyer EC

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GJC1 cDNA ORF clone, Canis lupus familiaris(dog)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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