CRP cDNA ORF clone, Canis lupus familiaris(Dog)

Gene
Clones
gRNAs

Summary

Gene Symbol	CRP
Entrez Gene ID	488629
Full Name	C-reactive protein
General protein information	Preferred Names C-reactive protein Names C-reactive protein
Gene Type	protein-coding
Organism	Canis lupus familiaris(Dog)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001314116.1	NP_001301045.1	C-reactive protein precursor
XM_545746.4	XP_545746.4	C-reactive protein

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	CRP	NP_001034653.1
Xenopus tropicalis (tropical clawed frog)	LOC100145348	NP_001120292.1
Xenopus tropicalis (tropical clawed frog)	LOC100487769	XP_004917388.1
Xenopus tropicalis (tropical clawed frog)	LOC100490829	XP_002937802.1
Xenopus tropicalis (tropical clawed frog)	LOC100489587	XP_002937795.1
Xenopus tropicalis (tropical clawed frog)	crp.2	NP_001011484.2
Canis lupus familiaris (dog)	CRP	XP_545746.4
Xenopus tropicalis (tropical clawed frog)	LOC496737	NP_001011284.1
Xenopus tropicalis (tropical clawed frog)	LOC100489659	XP_002943793.1
Xenopus tropicalis (tropical clawed frog)	LOC100489750	XP_002937796.1
Pan troglodytes (chimpanzee)	CRP	XP_001170732.2
	CRP	XP_001117250.1
Bos taurus (cattle)	CRP	NP_001137569.1
Rattus norvegicus (Norway rat)	Crp	NP_058792.1
Xenopus tropicalis (tropical clawed frog)	crp.4	NP_001135723.1
Xenopus tropicalis (tropical clawed frog)	apcs	NP_001008175.1
Xenopus tropicalis (tropical clawed frog)	LOC101734327	XP_004917560.1
Xenopus tropicalis (tropical clawed frog)	LOC100485832	XP_002937438.1
Xenopus tropicalis (tropical clawed frog)	LOC100486739	XP_002937444.2
Homo sapiens (human)	CRP	NP_000558.2
Xenopus tropicalis (tropical clawed frog)	MGC107876	NP_001015727.1
Xenopus tropicalis (tropical clawed frog)	LOC496665	NP_001011229.2
Xenopus tropicalis (tropical clawed frog)	MGC108147	NP_001015873.2
Xenopus tropicalis (tropical clawed frog)	LOC100135384	NP_001107522.1
Xenopus tropicalis (tropical clawed frog)	LOC100494488	XP_002934127.2
Mus musculus (house mouse)	Crp	NP_031794.3
Xenopus tropicalis (tropical clawed frog)	LOC496764	NP_001011309.1
Xenopus tropicalis (tropical clawed frog)	LOC101730495	XP_004917389.1
Xenopus tropicalis (tropical clawed frog)	LOC100494645	XP_002934128.1

Gene Ontology
Bibliography

Related articles in PubMed

Clinical assessment and C-reactive protein (CRP), haptoglobin (Hp), and cardiac troponin I (cTnI) values of brachycephalic dogs with upper airway obstruction before and after surgery.
Planellas M, Cuenca R, Tabar MD, Bertolani C, Poncet C, Closa JM, Lorente J, Cer?n JJ, Pastor J
Canadian journal of veterinary research = Revue canadienne de recherche veterinaire79(1)58-63(2015 Jan)

Characterization of the native C-reactive protein (cCRP) and the corresponding liver mRNA in dogs.
Jasensky AK, Bondzio A, Murugaiyan J, Siebert U, Roesler U, Kohn B, Einspanier R
Biochemical and biophysical research communications452(3)462-7(2014 Sep)

Evaluation of C-reactive protein, haptoglobin and cardiac troponin 1 levels in brachycephalic dogs with upper airway obstructive syndrome.
Planellas M, Cuenca R, Tabar MD, Bertolani C, Poncet C, Closa JM, Lorente J, Cer?n JJ, Pastor J
BMC veterinary research8152(2012 Aug)

Dogs with congenital porto-systemic shunting (cPSS) and hepatic encephalopathy have higher serum concentrations of C-reactive protein than asymptomatic dogs with cPSS.
Gow AG, Marques AI, Yool DA, Crawford K, Warman SM, Eckersall PD, Jalan R, Mellanby RJ
Metabolic brain disease27(2)227-9(2012 Jun)

The influence of high-intensity moderate duration exercise on cardiac troponin I and C-reactive protein in sled dogs.
Wakshlag JJ, Kraus MS, Gelzer AR, Downey RL, Vacchani P
Journal of veterinary internal medicine24(6)1388-92(2010 Nov-Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

No statistical differences were found between CRP and cTnI levels, either before or after surgical correction of brachycephaly in dogs.
Title: Clinical assessment and C-reactive protein (CRP), haptoglobin (Hp), and cardiac troponin I (cTnI) values of brachycephalic dogs with upper airway obstruction before and after surgery.

The two CRP canine isoforms have been characterized.
Title: Characterization of the native C-reactive protein (cCRP) and the corresponding liver mRNA in dogs.

The objective of this study was to evaluate the correlation between anatomical components, clinical signs and several biomarkers, used to determine systemic inflammation and myocardial damage in dogs with brachycephalic upper airway obstructive syndrome.
Title: Evaluation of C-reactive protein, haptoglobin and cardiac troponin 1 levels in brachycephalic dogs with upper airway obstructive syndrome.

There was a significant difference in CRP concentration between healthy dogs and dogs with hepatic encephalopathy and between dogs with hepatic encephalopathy and without hepatic encephalopathy
Title: Dogs with congenital porto-systemic shunting (cPSS) and hepatic encephalopathy have higher serum concentrations of C-reactive protein than asymptomatic dogs with cPSS.

Moderate exercise does not present a confounding variable in the interpretation of cardiac tropinin I and C-reactive protein concentrations in normal dogs.
Title: The influence of high-intensity moderate duration exercise on cardiac troponin I and C-reactive protein in sled dogs.

The following CRP gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CRP cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OCe140238	NM_001314116.1 Latest version!	Canis lupus familiaris C-reactive protein (CRP), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00
OCe31837	XM_545746.4 Latest version!	Canis lupus familiaris C-reactive protein, pentraxin-related (CRP), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CRP ( NM_001314116.1 ) cDNA ORF clone, Canis lupus familiaris(Dog) -> NP_001301045.1 Canis lupus familiaris C-reactive protein (CRP), mRNA.

Price & Availability↑

CloneID	OCe140238
Clone ID Related Accession (Same CDS sequence)	NM_001314116.1
Accession Version	NM_001314116.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 672bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-22
Organism	Canis lupus familiaris(dog)
Product	C-reactive protein precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from HG003655.1. On Oct 6, 2015 this sequence version replaced XM_545746.4. ##Evidence-Data-START## Transcript exon combination :: HG003655.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00013514, SAMN00013515 [ECO:0000348] ##Evidence-Data-END##

ATGGAGAAGC TGTGGCCTTG TCTCCTGGTC CTCATGAACC TCCCTGGTGC TTTTCTCCAG 
ATAGACCTGG ACGAAAAAGC CTTCGTGTTC CCCAGAGAAT CAGAGAATTC CTACGTGATC 
CTGTTTCCTC AGTTGCAGAA GCCGATGAAG GCTTTCACCG TGTGCCTGCA GGTCTATACG 
GACTTGACGC GCCCGCACAG CCTCTTCTCT TACGCCACCA AGTCACAAAG CAATGAGATC 
CTCCTCTTCA AGGAGAGGCC CGGCTTGTTC AGCGTATCCG TGGGCGGATC TGACGCCTTC 
ATCAATTTTC CTCAGAAGTT CTACGCGCCT CAGCACTTCT GCGTCACCTG GGAGTCCGTC 
ACGGGGCTCA CAGAGCTCTG GGTGGACGGC AAGCCCATGG TGAGGGCGAG TCTGAGGAGG 
GGGTACACCG TGGGGTCGGG AGCCAGCATC GTCCTCGGGC AGGAGCAGGA CTCGTTCGGT 
GGGGGCTTTG ATAAGAACCA GTCCTTGGTG GGCGACATCG AGGACGTGAA CATGTGGGAC 
TTTGTGCTGT CCCCAAGTCA GATTCTCACC CTCTACACCA CCAGGGCCTT GAGCCCTAAT 
GTCCTGAACT GGCGGAACCT GAGATATGAA ACCCGAGGTG AAGTGTTCCT CAAGAAGGAG 
CTGTGGTCCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001301045.1
CDS	7..678
Translation	MEKLWPCLLVLMNLPGAFLQIDLDEKAFVFPRESENSYVILFPQLQKPMKAFTVCLQVYTDLTRPHSLFSYATKSQSNEILLFKERPGLFSVSVGGSDAFINFPQKFYAPQHFCVTWESVTGLTELWVDGKPMVRASLRRGYTVGSGASIVLGQEQDSFGGGFDKNQSLVGDIEDVNMWDFVLSPSQILTLYTTRALSPNVLNWRNLRYETRGEVFLKKELWS

Target ORF information:

RefSeq Version	NM_001314116.1
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris C-reactive protein (CRP), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001314116.1

ORF Insert Sequence:

ATGGAGAAGC TGTGGCCTTG TCTCCTGGTC CTCATGAACC TCCCTGGTGC TTTTCTCCAG 
ATAGACCTGG ACGAAAAAGC CTTCGTGTTC CCCAGAGAAT CAGAGAATTC CTACGTGATC 
CTGTTTCCTC AGTTGCAGAA GCCGATGAAG GCTTTCACCG TGTGCCTGCA GGTCTATACG 
GACTTGACGC GCCCGCACAG CCTCTTCTCT TACGCCACCA AGTCACAAAG CAATGAGATC 
CTCCTCTTCA AGGAGAGGCC CGGCTTGTTC AGCGTATCCG TGGGCGGATC TGACGCCTTC 
ATCAATTTTC CTCAGAAGTT CTACGCGCCT CAGCACTTCT GCGTCACCTG GGAGTCCGTC 
ACGGGGCTCA CAGAGCTCTG GGTGGACGGC AAGCCCATGG TGAGGGCGAG TCTGAGGAGG 
GGGTACACCG TGGGGTCGGG AGCCAGCATC GTCCTCGGGC AGGAGCAGGA CTCGTTCGGT 
GGGGGCTTTG ATAAGAACCA GTCCTTGGTG GGCGACATCG AGGACGTGAA CATGTGGGAC 
TTTGTGCTGT CCCCAAGTCA GATTCTCACC CTCTACACCA CCAGGGCCTT GAGCCCTAAT 
GTCCTGAACT GGCGGAACCT GAGATATGAA ACCCGAGGTG AAGTGTTCCT CAAGAAGGAG 
CTGTGGTCCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CRP ( XM_545746.4 ) cDNA ORF clone, Canis lupus familiaris(Dog) -> XP_545746.4 Canis lupus familiaris C-reactive protein, pentraxin-related (CRP), mRNA.

Price & Availability↑

CloneID	OCe31837
Clone ID Related Accession (Same CDS sequence)	XM_545746.4
Accession Version	XM_545746.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 747bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2013-09-23
Organism	Canis lupus familiaris(Dog)
Product	C-reactive protein
Comment

ATGGACATCT CAGCTGCTGA CCCTCTTTCC GGGACGATAA CCCAGATTCT GCGCACAGTG 
ACGCAGGGAG GAGTCATGGA GAAGCTGTGG CCTTGTCTCC TGGTCCTCAT GAACCTCCCT 
GGTGCTTTTC TCCAGATAGA CCTGGACGAA AAAGCCTTCG TGTTCCCCAG AGAATCAGAG 
AATTCCTACG TGATCCTGTT TCCTCAGTTG CAGAAGCCGA TGAAGGCTTT CACCGTGTGC 
CTGCAGGTCT ATACGGACTT GACGCGCCCG CACAGCCTCT TCTCTTACGC CACCAAGTCA 
CAAAGCAATG AGATCCTCCT CTTCAAGGAG AGGCCCGGCT TGTTCAGCGT ATCCGTGGGC 
GGATCTGACG CCTTCATCAA TTTTCCTCAG AAGTTCTACG CGCCTCAGCA CTTCTGCGTC 
ACCTGGGAGT CCGTCACGGG GCTCACAGAG CTCTGGGTGG ACGGCAAGCC CATGGTGAGG 
GCGAGTCTGA GGAGGGGGTA CACCGTGGGG TCGGGAGCCA GCATCGTCCT CGGGCAGGAG 
CAGGACTCGT TCGGTGGGGG CTTTGATAAG AACCAGTCCT TGGTGGGCGA CATCGAGGAC 
GTGAACATGT GGGACTTTGT GCTGTCCCCA AGTCAGATTC TCACCCTCTA CACCACCAGG 
GCCTTGAGCC CTAATGTCCT GAACTGGCGG AACCTGAGAT ATGAAACCCG AGGTGAAGTG 
TTCCTCAAGA AGGAGCTGTG GTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_545746.4
Translation	MDISAADPLSGTITQILRTVTQGGVMEKLWPCLLVLMNLPGAFLQIDLDEKAFVFPRESENSYVILFPQLQKPMKAFTVCLQVYTDLTRPHSLFSYATKSQSNEILLFKERPGLFSVSVGGSDAFINFPQKFYAPQHFCVTWESVTGLTELWVDGKPMVRASLRRGYTVGSGASIVLGQEQDSFGGGFDKNQSLVGDIEDVNMWDFVLSPSQILTLYTTRALSPNVLNWRNLRYETRGEVFLKKELWS

Target ORF information:

RefSeq Version	XM_545746.4
Organism	Canis lupus familiaris(Dog)
Definition	Canis lupus familiaris C-reactive protein, pentraxin-related (CRP), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_545746.4

ORF Insert Sequence:

ATGGACATCT CAGCTGCTGA CCCTCTTTCC GGGACGATAA CCCAGATTCT GCGCACAGTG 
ACGCAGGGAG GAGTCATGGA GAAGCTGTGG CCTTGTCTCC TGGTCCTCAT GAACCTCCCT 
GGTGCTTTTC TCCAGATAGA CCTGGACGAA AAAGCCTTCG TGTTCCCCAG AGAATCAGAG 
AATTCCTACG TGATCCTGTT TCCTCAGTTG CAGAAGCCGA TGAAGGCTTT CACCGTGTGC 
CTGCAGGTCT ATACGGACTT GACGCGCCCG CACAGCCTCT TCTCTTACGC CACCAAGTCA 
CAAAGCAATG AGATCCTCCT CTTCAAGGAG AGGCCCGGCT TGTTCAGCGT ATCCGTGGGC 
GGATCTGACG CCTTCATCAA TTTTCCTCAG AAGTTCTACG CGCCTCAGCA CTTCTGCGTC 
ACCTGGGAGT CCGTCACGGG GCTCACAGAG CTCTGGGTGG ACGGCAAGCC CATGGTGAGG 
GCGAGTCTGA GGAGGGGGTA CACCGTGGGG TCGGGAGCCA GCATCGTCCT CGGGCAGGAG 
CAGGACTCGT TCGGTGGGGG CTTTGATAAG AACCAGTCCT TGGTGGGCGA CATCGAGGAC 
GTGAACATGT GGGACTTTGT GCTGTCCCCA AGTCAGATTC TCACCCTCTA CACCACCAGG 
GCCTTGAGCC CTAATGTCCT GAACTGGCGG AACCTGAGAT ATGAAACCCG AGGTGAAGTG 
TTCCTCAAGA AGGAGCTGTG GTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Clinical assessment and C-reactive protein (CRP), haptoglobin (Hp), and cardiac troponin I (cTnI) values of brachycephalic dogs with upper airway obstruction before and after surgery.
Canadian journal of veterinary research = Revue canadienne de recherche veterinaire79(1)58-63(2015 Jan)
Planellas M,Cuenca R,Tabar MD,Bertolani C,Poncet C,Closa JM,Lorente J,Cer?n JJ,Pastor J

Characterization of the native C-reactive protein (cCRP) and the corresponding liver mRNA in dogs.
Biochemical and biophysical research communications452(3)462-7(2014 Sep)
Jasensky AK,Bondzio A,Murugaiyan J,Siebert U,Roesler U,Kohn B,Einspanier R

Evaluation of C-reactive protein, haptoglobin and cardiac troponin 1 levels in brachycephalic dogs with upper airway obstructive syndrome.
BMC veterinary research8152(2012 Aug)
Planellas M,Cuenca R,Tabar MD,Bertolani C,Poncet C,Closa JM,Lorente J,Cer?n JJ,Pastor J

Dogs with congenital porto-systemic shunting (cPSS) and hepatic encephalopathy have higher serum concentrations of C-reactive protein than asymptomatic dogs with cPSS.
Metabolic brain disease27(2)227-9(2012 Jun)
Gow AG,Marques AI,Yool DA,Crawford K,Warman SM,Eckersall PD,Jalan R,Mellanby RJ

The influence of high-intensity moderate duration exercise on cardiac troponin I and C-reactive protein in sled dogs.
Journal of veterinary internal medicine24(6)1388-92(2010 Nov-Dec)
Wakshlag JJ,Kraus MS,Gelzer AR,Downey RL,Vacchani P

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CRP cDNA ORF clone, Canis lupus familiaris(Dog)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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