RAPGEF3 cDNA ORF clone, Canis lupus familiaris(dog)

Gene
Clones
gRNAs

Summary

Gene Symbol	RAPGEF3
Entrez Gene ID	486591
Full Name	Rap guanine nucleotide exchange factor 3
General protein information	Preferred Names Rap guanine nucleotide exchange factor 3 Names rap guanine nucleotide exchange factor 3 exchange protein directly activated by cAMP 1
Gene Type	protein-coding
Organism	Canis lupus familiaris(dog)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001099944.1	NP_001093414.1	rap guanine nucleotide exchange factor 3

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	RAPGEF3	XP_001162479.2
Xenopus tropicalis (tropical clawed frog)	rapgef3	XP_002935702.2
Rattus norvegicus (Norway rat)	Rapgef3	NP_067722.1
Danio rerio (zebrafish)	LOC101886094	XP_005162410.1
	RAPGEF3	XP_001098291.2
Gallus gallus (chicken)	RAPGEF3	XP_424494.4
Bos taurus (cattle)	RAPGEF3	NP_001073771.1
Homo sapiens (human)	RAPGEF3	NP_001092001.1
Canis lupus familiaris (dog)	RAPGEF3	NP_001093414.1
Mus musculus (house mouse)	Rapgef3	NP_001171281.1

Gene Ontology
Bibliography

Related articles in PubMed

Cyclic adenosine 3',5'-monophosphate (cAMP)-dependent protein kinases, but not exchange proteins directly activated by cAMP (Epac), mediate thyrotropin/cAMP-dependent regulation of thyroid cells.
Dremier S, Milenkovic M, Blancquaert S, Dumont JE, D?skeland SO, Maenhaut C, Roger PP
Endocrinology148(10)4612-22(2007 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following RAPGEF3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RAPGEF3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OCe34072	NM_001099944.1 Latest version!	Canis lupus familiaris Rap guanine nucleotide exchange factor 3 (RAPGEF3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$510.30 $729.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RAPGEF3 ( NM_001099944.1 ) cDNA ORF clone, Canis lupus familiaris(dog) -> NP_001093414.1 Canis lupus familiaris Rap guanine nucleotide exchange factor 3 (RAPGEF3), mRNA.

Price & Availability↑

CloneID	OCe34072
Clone ID Related Accession (Same CDS sequence)	NM_001099944.1
Accession Version	NM_001099944.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2646bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-30
Organism	Canis lupus familiaris(dog)
Product	rap guanine nucleotide exchange factor 3
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from EF636666.1. On Jul 26, 2007 this sequence version replaced XM_543717.2. ##Evidence-Data-START## Transcript exon combination :: EF636666.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA103936001, SAMEA103936002 [ECO:0000350] ##Evidence-Data-END##

ATGGTGCTGA AGAGGATGCA CCGGCCCCGA AGCTGTTCCT ACCAGCTGCT GCTCGAGCAC 
CAGCGTCCCA GCCGCATCCA GGGGCTCCGC TGGACGCCAC TCACCGACAG CGAGGAGTCC 
CTGGATTTCA GCGAGAGCCT GGAGCAGGCC TCCACGGAGA GGGTGCTCAG GGCGGGGAAG 
CAGCTGCATC GACACCTCCT GGCCACCTCT CCGACCCTTA TCCGAGACCG GAAATACCAC 
CTTCGGCTCT ATCGGCAGTG CTGCTCTGGC CGGGAGCTCG TGGATGGCAT CTTGGCCCTG 
GGCCTCGGGG TCCACTCCCG GAGCCAGGCC GTTGGAATCT GCCAGGTGCT GCTGGATGAA 
GGTGCCCTCT GCCATGTGAA ACACGACTGG ACCTTCCAGG ACCGAGATAC CCAATTCTAC 
CGATTTCCCG GGCCGGAGCC AGAGCCCGCG GGCGTCCATG AGCTGGAGGA GGAGCTGGTC 
GAGGCCGTGG CCCTGCTCTC CCAGCGGGGC CCCGACGCCC TGCTCACCGT GGCCCTGCGA 
AAGCCCCCGG GTCAGCGCAC GGACGAGGAG CTGGACCTCA TCTTTGAGGA GCTGCTGCAC 
ATCAAGGCTG TGGCCCATCT CTCCAACTCG GTGAAGCGGG AATTAGCGGC AGTTCTGCTC 
TTTGAACCGC ACAGCAAAGC GGGGACCGTG TTGTTCAGCC AGGGAGACAA GGGCACCTCG 
TGGTACATCA TCTGGAAGGG ATCTGTCAAC GTGGTGACCC ATGGCAAGGG GCTGGTGACC 
ACCCTGCATG AGGGAGATGA CTTTGGGCAG CTGGCTCTGG TGAACGACGC GCCCCGGGCA 
GCCACCATCA TCCTGCGAGA AGACAACTGT CATTTCCTTC GCGTGGACAA GCAGGACTTC 
AACCGTATCA TCAAGGATGT GGAAGCCAAG ACCATGAGGC TAGAAGAACA TGGCAAAGTG 
GTGTTGGTAC TGGAGAGAGC CTCTCAGGGT GCCGGCCCTT CTCGCCCCCC GACCCCAGGC 
AGGAACCGGT ATACGGTGAT GTCTGGCACC CCAGAGAAGA TCCTAGAACT GCTGTTGGAG 
GCCATGCGAC CTGATTCCAG TGCTCATGAC CCAACAGAGA CATTCCTCAG TGACTTCCTC 
CTGACCTACA GCGTCTTCAT GCCCAGTGCC CAGCTCTGTG CTGCCCTCCT GCACCACTTC 
CACGCGGAGC CCTCGGGAGG CAGTGAGCAG GAGCACAGCA CCTACATTTG CAACAAAAGG 
CAGCAGATCC TGCGGCTGGT CAGCCAATGG GTGGCCCTGT ATGGCCCCAT GCTCTACACC 
GACCCCGTGG CCACCGGCTT TCTCCAGAAA CTCTCAGACC TGGTGAGCAG AGACACCCGG 
CTTTGCATCC TGCTGCGGGA GCAGTGGCCA GAGAGGCGGC GACACCACAG GTTGGAGAAC 
GGCTGTGGGA ATGCATCTCC TCAGATGAAG GCCAGGAACA TGCCTGTTTG GCTCCCCGGC 
CAGGACCAGC CCCTCCTCTG CAGCAACCGT GCCATTCGAG TCGGGGACAA AGTCCCCTAT 
GACATTTGCC GGCCGGACCA CTCGGTGCTC ACCCTGAAGC TGCCCGTGAC GGCCTCGGTG 
AGAGAGGTGA TGGCAGCGTT GGCCCAGGAG GATGGCTGGA CCAAGGGGCA GGTGCTGGTG 
AAGGTCAACT CTGCAGGTGA TGCCATTGGC CTGCAGCCGG ATGCCCGTGG TGTGGCCACA 
TCCCTGGGGC TCAACGAGCG GCTCTTTGTT GTCAACCCAC AGGAAGTGCA TGAGCTGACC 
CCACACCCCG AGCAGCTGGG GCCCACCGTG GGCTCTGCTG AGGGCCTGGA CCTGGTGAGC 
GCCAAGGACC TGGCGGGCCA GCTGACGGAC CACGACTGGA ACCTCTTCAA CAGTATCCAC 
CAGGTGGAGC TGATCCACTA TGTGCTGGGC CCCCAGCATC TGCGGGACGT CACCACTGCC 
AACCTGGAGC GTTTCATGCG CCGCTTCAAC GAGCTACAGT ACTGGGTGGC CACAGAGCTG 
TGTCTCTGCC CTGTGCCGGG CTTGCGGGCC CAGCTGCTCA GGAAGTTCAT CAAGCTGGCT 
GCCCACCTCA AGGAGCAGAA GAATCTCAAT TCCTTCTTCG CTGTCATGTT TGGCCTCAGC 
AACTCGGCCA TCAGCCGCCT GGCCCACACC TGGGAGCGGC TGCCCCACAA AGTCCGGAAG 
CTGTACTCGG CCCTCGAGAG GCTGCTGGAC CCTTCGTGGA ACCACCGAGT CTATCGACTG 
GCCCTCACCA AGCTCTCCCC TCCCATCATC CCCTTCATGC CTCTTCTTCT CAAAGACATG 
ACCTTCATCC ATGAGGGGAA CCACACACTG GTGGAGAATC TCATCAACTT TGAGAAGATG 
AGAATGATGG CCAGAGCCGT GCGGATGCTG CACCACTGCC GAAGCCACAG CAACGTGCCC 
CTCTCACCAC TCAGAAGCCG CGTATCCCAC CTCCACGAGG ACAGCCAGGC AGCAAGGACA 
TCCACGTGCT CCGAGCAGTC CCTGAGCACC CGGAGCGCAG CCAGCACCTG GGCGTACGTC 
CAGCAGCTGA AGGTCATCGA CAACCAGCGG GAGCTGTCCC GCCTGTCCCG CGAGCTGGAG 
CCGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001093414.1
CDS	236..2881
Translation	MVLKRMHRPRSCSYQLLLEHQRPSRIQGLRWTPLTDSEESLDFSESLEQASTERVLRAGKQLHRHLLATSPTLIRDRKYHLRLYRQCCSGRELVDGILALGLGVHSRSQAVGICQVLLDEGALCHVKHDWTFQDRDTQFYRFPGPEPEPAGVHELEEELVEAVALLSQRGPDALLTVALRKPPGQRTDEELDLIFEELLHIKAVAHLSNSVKRELAAVLLFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNVVTHGKGLVTTLHEGDDFGQLALVNDAPRAATIILREDNCHFLRVDKQDFNRIIKDVEAKTMRLEEHGKVVLVLERASQGAGPSRPPTPGRNRYTVMSGTPEKILELLLEAMRPDSSAHDPTETFLSDFLLTYSVFMPSAQLCAALLHHFHAEPSGGSEQEHSTYICNKRQQILRLVSQWVALYGPMLYTDPVATGFLQKLSDLVSRDTRLCILLREQWPERRRHHRLENGCGNASPQMKARNMPVWLPGQDQPLLCSNRAIRVGDKVPYDICRPDHSVLTLKLPVTASVREVMAALAQEDGWTKGQVLVKVNSAGDAIGLQPDARGVATSLGLNERLFVVNPQEVHELTPHPEQLGPTVGSAEGLDLVSAKDLAGQLTDHDWNLFNSIHQVELIHYVLGPQHLRDVTTANLERFMRRFNELQYWVATELCLCPVPGLRAQLLRKFIKLAAHLKEQKNLNSFFAVMFGLSNSAISRLAHTWERLPHKVRKLYSALERLLDPSWNHRVYRLALTKLSPPIIPFMPLLLKDMTFIHEGNHTLVENLINFEKMRMMARAVRMLHHCRSHSNVPLSPLRSRVSHLHEDSQAARTSTCSEQSLSTRSAASTWAYVQQLKVIDNQRELSRLSRELEP

Target ORF information:

RefSeq Version	NM_001099944.1
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris Rap guanine nucleotide exchange factor 3 (RAPGEF3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001099944.1

ORF Insert Sequence:

ATGGTGCTGA AGAGGATGCA CCGGCCCCGA AGCTGTTCCT ACCAGCTGCT GCTCGAGCAC 
CAGCGTCCCA GCCGCATCCA GGGGCTCCGC TGGACGCCAC TCACCGACAG CGAGGAGTCC 
CTGGATTTCA GCGAGAGCCT GGAGCAGGCC TCCACGGAGA GGGTGCTCAG GGCGGGGAAG 
CAGCTGCATC GACACCTCCT GGCCACCTCT CCGACCCTTA TCCGAGACCG GAAATACCAC 
CTTCGGCTCT ATCGGCAGTG CTGCTCTGGC CGGGAGCTCG TGGATGGCAT CTTGGCCCTG 
GGCCTCGGGG TCCACTCCCG GAGCCAGGCC GTTGGAATCT GCCAGGTGCT GCTGGATGAA 
GGTGCCCTCT GCCATGTGAA ACACGACTGG ACCTTCCAGG ACCGAGATAC CCAATTCTAC 
CGATTTCCCG GGCCGGAGCC AGAGCCCGCG GGCGTCCATG AGCTGGAGGA GGAGCTGGTC 
GAGGCCGTGG CCCTGCTCTC CCAGCGGGGC CCCGACGCCC TGCTCACCGT GGCCCTGCGA 
AAGCCCCCGG GTCAGCGCAC GGACGAGGAG CTGGACCTCA TCTTTGAGGA GCTGCTGCAC 
ATCAAGGCTG TGGCCCATCT CTCCAACTCG GTGAAGCGGG AATTAGCGGC AGTTCTGCTC 
TTTGAACCGC ACAGCAAAGC GGGGACCGTG TTGTTCAGCC AGGGAGACAA GGGCACCTCG 
TGGTACATCA TCTGGAAGGG ATCTGTCAAC GTGGTGACCC ATGGCAAGGG GCTGGTGACC 
ACCCTGCATG AGGGAGATGA CTTTGGGCAG CTGGCTCTGG TGAACGACGC GCCCCGGGCA 
GCCACCATCA TCCTGCGAGA AGACAACTGT CATTTCCTTC GCGTGGACAA GCAGGACTTC 
AACCGTATCA TCAAGGATGT GGAAGCCAAG ACCATGAGGC TAGAAGAACA TGGCAAAGTG 
GTGTTGGTAC TGGAGAGAGC CTCTCAGGGT GCCGGCCCTT CTCGCCCCCC GACCCCAGGC 
AGGAACCGGT ATACGGTGAT GTCTGGCACC CCAGAGAAGA TCCTAGAACT GCTGTTGGAG 
GCCATGCGAC CTGATTCCAG TGCTCATGAC CCAACAGAGA CATTCCTCAG TGACTTCCTC 
CTGACCTACA GCGTCTTCAT GCCCAGTGCC CAGCTCTGTG CTGCCCTCCT GCACCACTTC 
CACGCGGAGC CCTCGGGAGG CAGTGAGCAG GAGCACAGCA CCTACATTTG CAACAAAAGG 
CAGCAGATCC TGCGGCTGGT CAGCCAATGG GTGGCCCTGT ATGGCCCCAT GCTCTACACC 
GACCCCGTGG CCACCGGCTT TCTCCAGAAA CTCTCAGACC TGGTGAGCAG AGACACCCGG 
CTTTGCATCC TGCTGCGGGA GCAGTGGCCA GAGAGGCGGC GACACCACAG GTTGGAGAAC 
GGCTGTGGGA ATGCATCTCC TCAGATGAAG GCCAGGAACA TGCCTGTTTG GCTCCCCGGC 
CAGGACCAGC CCCTCCTCTG CAGCAACCGT GCCATTCGAG TCGGGGACAA AGTCCCCTAT 
GACATTTGCC GGCCGGACCA CTCGGTGCTC ACCCTGAAGC TGCCCGTGAC GGCCTCGGTG 
AGAGAGGTGA TGGCAGCGTT GGCCCAGGAG GATGGCTGGA CCAAGGGGCA GGTGCTGGTG 
AAGGTCAACT CTGCAGGTGA TGCCATTGGC CTGCAGCCGG ATGCCCGTGG TGTGGCCACA 
TCCCTGGGGC TCAACGAGCG GCTCTTTGTT GTCAACCCAC AGGAAGTGCA TGAGCTGACC 
CCACACCCCG AGCAGCTGGG GCCCACCGTG GGCTCTGCTG AGGGCCTGGA CCTGGTGAGC 
GCCAAGGACC TGGCGGGCCA GCTGACGGAC CACGACTGGA ACCTCTTCAA CAGTATCCAC 
CAGGTGGAGC TGATCCACTA TGTGCTGGGC CCCCAGCATC TGCGGGACGT CACCACTGCC 
AACCTGGAGC GTTTCATGCG CCGCTTCAAC GAGCTACAGT ACTGGGTGGC CACAGAGCTG 
TGTCTCTGCC CTGTGCCGGG CTTGCGGGCC CAGCTGCTCA GGAAGTTCAT CAAGCTGGCT 
GCCCACCTCA AGGAGCAGAA GAATCTCAAT TCCTTCTTCG CTGTCATGTT TGGCCTCAGC 
AACTCGGCCA TCAGCCGCCT GGCCCACACC TGGGAGCGGC TGCCCCACAA AGTCCGGAAG 
CTGTACTCGG CCCTCGAGAG GCTGCTGGAC CCTTCGTGGA ACCACCGAGT CTATCGACTG 
GCCCTCACCA AGCTCTCCCC TCCCATCATC CCCTTCATGC CTCTTCTTCT CAAAGACATG 
ACCTTCATCC ATGAGGGGAA CCACACACTG GTGGAGAATC TCATCAACTT TGAGAAGATG 
AGAATGATGG CCAGAGCCGT GCGGATGCTG CACCACTGCC GAAGCCACAG CAACGTGCCC 
CTCTCACCAC TCAGAAGCCG CGTATCCCAC CTCCACGAGG ACAGCCAGGC AGCAAGGACA 
TCCACGTGCT CCGAGCAGTC CCTGAGCACC CGGAGCGCAG CCAGCACCTG GGCGTACGTC 
CAGCAGCTGA AGGTCATCGA CAACCAGCGG GAGCTGTCCC GCCTGTCCCG CGAGCTGGAG 
CCGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Cyclic adenosine 3',5'-monophosphate (cAMP)-dependent protein kinases, but not exchange proteins directly activated by cAMP (Epac), mediate thyrotropin/cAMP-dependent regulation of thyroid cells.
Endocrinology148(10)4612-22(2007 Oct)
Dremier S,Milenkovic M,Blancquaert S,Dumont JE,D?skeland SO,Maenhaut C,Roger PP

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RAPGEF3 cDNA ORF clone, Canis lupus familiaris(dog)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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