LTF cDNA ORF clone, Canis lupus familiaris(dog)

Gene
Clones
gRNAs

Summary

Gene Symbol	LTF
Entrez Gene ID	484787
Full Name	lactotransferrin
General protein information	Preferred Names lactotransferrin Names lactotransferrin lactoferrin
Gene Type	protein-coding
Organism	Canis lupus familiaris(dog)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001287076.1	NP_001274005.1	lactotransferrin precursor

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	LTF	XP_541903.2
Bos taurus (cattle)	LTF	NP_851341.1
Pan troglodytes (chimpanzee)	LTF	XP_516417.2
Mus musculus (house mouse)	Ltf	NP_032548.2
Rattus norvegicus (Norway rat)	Ltf	NP_001100334.1
Homo sapiens (human)	LTF	NP_002334.2

Gene Ontology
Bibliography

Related articles in PubMed

Analysis of new lactotransferrin gene variants in a case-control study related to periodontal disease in dog.
Morinha F, Albuquerque C, Requicha J, Dias I, Leit?o J, Gut I, Guedes-Pinto H, Viegas C, Bastos E
Molecular biology reports39(4)4673-81(2012 Apr)

Lactoferrin from canine neutrophils: isolation and physicochemical and antimicrobial properties.
Berlov MN, Korableva ES, Andreeva YV, Ovchinnikova TV, Kokryakov VN
Biochemistry. Biokhimiia72(4)445-51(2007 Apr)

Lactoferrin expression in the canine uterus during the estrous cycle and with pyometra.
Kida K, Baba E, Torii R, Kawate N, Hatoya S, Wijewardana V, Sugiura K, Sawada T, Tamada H, Inaba T
Theriogenology66(5)1325-33(2006 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The sequence variant L/15_g.411C > T leads to an aminoacid change (Proline to Leucine) and was predicted to be possibly damaging to the LTF protein.
Title: Analysis of new lactotransferrin gene variants in a case-control study related to periodontal disease in dog.

study shows that canine lactoferrin resembles the human homolog in some physicochemical properties: molecular weight, carbohydrate presence & conditions of protein-iron complex dissociation; bactericidal activity is similar to that of human lactoferrin
Title: Lactoferrin from canine neutrophils: isolation and physicochemical and antimicrobial properties.

The following LTF gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LTF cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OCe34068	NM_001287076.1 Latest version!	Canis lupus familiaris lactotransferrin (LTF), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$426.30 $609.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

LTF ( NM_001287076.1 ) cDNA ORF clone, Canis lupus familiaris(dog) -> NP_001274005.1 Canis lupus familiaris lactotransferrin (LTF), mRNA.

Price & Availability↑

CloneID	OCe34068
Clone ID Related Accession (Same CDS sequence)	NM_001287076.1
Accession Version	NM_001287076.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2127bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-22
Organism	Canis lupus familiaris(dog)
Product	lactotransferrin precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AAEX03012246.1 and AAEX03012247.1. On Nov 26, 2013 this sequence version replaced XM_541903.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments and orthologous data. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA103936001, SAMEA2240594 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END##

ATGAAGCTAG TTTTTCCTGC CCTGCTCTTC CTCGGGGCCC TTGGACTGTG TCTGGCCGCC 
CCTAGGAAAA ATGTTCGATG GTGCACCACA TCAAAAGCAG AGGCAAAAAA ATGCTCCAAA 
TTCCAAGTGA ATATGAAAAA AGTAGGTGGC CCCATTGTCT CCTGTACAAG GAAAGCCTCC 
CGCCAAGAAT GTATCCAGGC TATCAAGGCA AACAAGGCAG ATGCTGTGAC CCTGGATGGT 
GGTTTGGTGT TTGAGGCAGG CCTGGAGCCC AACAAACTGC GACCTATAGC GGCTGAGGTG 
TATGGTACCC AAACAAAGCA ACAAATCCAC TATTATGCTG TGGCCATAGC AAAGAAAGGC 
ACCAACTTCC AGCTAAACCA ACTACAGGGC GTGAGGTCCT GCCACACAGG CCTTGGCAGG 
TCTGCGGGAT GGAACATCCC TATAGGTACC CTTCGTCCAT TCTTAAACTG GACAGGGCCA 
CCTGAGCCCC TTGAGGAAGC TGTAGCCAAA TTCTTCTCTG CCAGCTGTGT GCCCTGTGCA 
GATGGAAAAC AGTACCCTAA CCTGTGTCGC CTGTGTGCGG GGACAGAGCA AAATAAATGT 
GCCTGCTCCT CCCAGGAACC ATACTTCGGC TACTCTGGTG CCTTCAAGTG TCTGCAAGAT 
GGGGCTGGAG ATGTGGCTTT TGTCAGGGAC AGCACAGTGT TTGAGAACCT GCCAGACAAG 
GCTGACCAGG ACAAGTATGA GCTGCTCTGC TTAAATAACA CTCGGAAGCC AGTGGACGCA 
TTCAAGGATT GCCACCTGGC CCGGGTCCCT TCTCATGCTG TTGTGGCCCG AAGTGTGGGT 
GGCAAGGAGG ACTTGATCTG GAGGCTTCTT CAGAAGGCAC AGGAAAATTT TGGAAAAGAC 
AAGTCATCTG CATTCCAGCT CTTTGGCTCT CCTAGTGGGG AAAAGGATTT GCTGTTCAAA 
GACTCTGCCA TTGGGTTTTT GAGGATTCCC TCAAATATAG ATTCTGAGCT GTACCTTGGC 
TTCAACTACA TCAACGCCAT CCAGAGCCTG AAGGAAAAGG ATTCGGACTC GGCGGAGCGG 
CGCGCGCGGG TGGCGTGGTG CGCGGTGGGC GAGGCGGAGC AGCGCAAGTG CGAGCGGTGG 
GTGCGCGCCA GCGGCGGGAG CGTGAGCTGC GTATCGGCGC CCAGCGGGGA GGACTGCATC 
GCGCTGGTCC TGAAAGGAAA AGCTGATGCC CTGAGCCTGG ATGGAGGACT TATCTATGTT 
GCGGGCAAGT GTGGTTTGGT GCCTGTCCTG GCAGAGAACC AAAAATCACA GAACCCTAGT 
GACGTAGATT GTGTGGATAG ACTGGCGGAA GGTTACCTTG CTGTGGCCGT TGTCAGGAAA 
TCAGATGCCG ATCTCACCTG GAACACTCTG AGAGGCAGGA AGTCCTGCCA CACTGCTGTG 
GGCAGGACTG CAGGCTGGAA CATCCCCATG GGCCTGCTCT TCAACCAGTT AGGCTCCTGC 
AAATTTGATG AATTCTTTAG CCAGAGCTGT GCCCCTGGGG CCGACCCGAA GTCCAGTCTC 
TGCGCACTGT GCATTGGTGA CGAGAAGGGT GAGAACAAGT GTGCGCCCAA CAATAGTGAG 
AGATACTTTG GCTACACCGG GGCTTTCAGG TGCCTGGCAG AGAAGGCTGG AGATGTCGCA 
TTTGTGAGAG ATTCCACTAT CTTGCAGAAC ACAAACGGAG GGAACCCTGA GCCATGGGCC 
AGGGATTTGA AGCTGGAGGA CTTTGAGCTG CTGTGTCTTG ATGGCACCCG GCAGCCTGTG 
ACAAAGGCTC GGAGATGTCA CCTGGCCATG GCTCCGAACC ATGCTGTGGT ATCTCGGGAA 
GAAAAGGCCG AACACCTGAA GCAGGTGCTG CTCCTCCAGC AGACGCGGTT TGGAAGAAAT 
GGAACCAAAT GCCCAAGCGA GTTTTGCTTG TTCCAGTCTG AAACCAAAAA TCTTCTGTTC 
AATGACAACA CTGAGTGTCT GGCCAAACTC CAAGGCAAAA ACACATATGA AGAATATTTG 
GGATCAGCCT ATGTCACGGC CGTTGCTAAT CTGAGACAGT GTTCAGCCTC CCCGCTTCTG 
GAAGCCTGCG CCTTCCTGAG GAGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001274005.1
CDS	102..2228
Translation	MKLVFPALLFLGALGLCLAAPRKNVRWCTTSKAEAKKCSKFQVNMKKVGGPIVSCTRKASRQECIQAIKANKADAVTLDGGLVFEAGLEPNKLRPIAAEVYGTQTKQQIHYYAVAIAKKGTNFQLNQLQGVRSCHTGLGRSAGWNIPIGTLRPFLNWTGPPEPLEEAVAKFFSASCVPCADGKQYPNLCRLCAGTEQNKCACSSQEPYFGYSGAFKCLQDGAGDVAFVRDSTVFENLPDKADQDKYELLCLNNTRKPVDAFKDCHLARVPSHAVVARSVGGKEDLIWRLLQKAQENFGKDKSSAFQLFGSPSGEKDLLFKDSAIGFLRIPSNIDSELYLGFNYINAIQSLKEKDSDSAERRARVAWCAVGEAEQRKCERWVRASGGSVSCVSAPSGEDCIALVLKGKADALSLDGGLIYVAGKCGLVPVLAENQKSQNPSDVDCVDRLAEGYLAVAVVRKSDADLTWNTLRGRKSCHTAVGRTAGWNIPMGLLFNQLGSCKFDEFFSQSCAPGADPKSSLCALCIGDEKGENKCAPNNSERYFGYTGAFRCLAEKAGDVAFVRDSTILQNTNGGNPEPWARDLKLEDFELLCLDGTRQPVTKARRCHLAMAPNHAVVSREEKAEHLKQVLLLQQTRFGRNGTKCPSEFCLFQSETKNLLFNDNTECLAKLQGKNTYEEYLGSAYVTAVANLRQCSASPLLEACAFLRR

Target ORF information:

RefSeq Version	NM_001287076.1
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris lactotransferrin (LTF), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001287076.1

ORF Insert Sequence:

ATGAAGCTAG TTTTTCCTGC CCTGCTCTTC CTCGGGGCCC TTGGACTGTG TCTGGCCGCC 
CCTAGGAAAA ATGTTCGATG GTGCACCACA TCAAAAGCAG AGGCAAAAAA ATGCTCCAAA 
TTCCAAGTGA ATATGAAAAA AGTAGGTGGC CCCATTGTCT CCTGTACAAG GAAAGCCTCC 
CGCCAAGAAT GTATCCAGGC TATCAAGGCA AACAAGGCAG ATGCTGTGAC CCTGGATGGT 
GGTTTGGTGT TTGAGGCAGG CCTGGAGCCC AACAAACTGC GACCTATAGC GGCTGAGGTG 
TATGGTACCC AAACAAAGCA ACAAATCCAC TATTATGCTG TGGCCATAGC AAAGAAAGGC 
ACCAACTTCC AGCTAAACCA ACTACAGGGC GTGAGGTCCT GCCACACAGG CCTTGGCAGG 
TCTGCGGGAT GGAACATCCC TATAGGTACC CTTCGTCCAT TCTTAAACTG GACAGGGCCA 
CCTGAGCCCC TTGAGGAAGC TGTAGCCAAA TTCTTCTCTG CCAGCTGTGT GCCCTGTGCA 
GATGGAAAAC AGTACCCTAA CCTGTGTCGC CTGTGTGCGG GGACAGAGCA AAATAAATGT 
GCCTGCTCCT CCCAGGAACC ATACTTCGGC TACTCTGGTG CCTTCAAGTG TCTGCAAGAT 
GGGGCTGGAG ATGTGGCTTT TGTCAGGGAC AGCACAGTGT TTGAGAACCT GCCAGACAAG 
GCTGACCAGG ACAAGTATGA GCTGCTCTGC TTAAATAACA CTCGGAAGCC AGTGGACGCA 
TTCAAGGATT GCCACCTGGC CCGGGTCCCT TCTCATGCTG TTGTGGCCCG AAGTGTGGGT 
GGCAAGGAGG ACTTGATCTG GAGGCTTCTT CAGAAGGCAC AGGAAAATTT TGGAAAAGAC 
AAGTCATCTG CATTCCAGCT CTTTGGCTCT CCTAGTGGGG AAAAGGATTT GCTGTTCAAA 
GACTCTGCCA TTGGGTTTTT GAGGATTCCC TCAAATATAG ATTCTGAGCT GTACCTTGGC 
TTCAACTACA TCAACGCCAT CCAGAGCCTG AAGGAAAAGG ATTCGGACTC GGCGGAGCGG 
CGCGCGCGGG TGGCGTGGTG CGCGGTGGGC GAGGCGGAGC AGCGCAAGTG CGAGCGGTGG 
GTGCGCGCCA GCGGCGGGAG CGTGAGCTGC GTATCGGCGC CCAGCGGGGA GGACTGCATC 
GCGCTGGTCC TGAAAGGAAA AGCTGATGCC CTGAGCCTGG ATGGAGGACT TATCTATGTT 
GCGGGCAAGT GTGGTTTGGT GCCTGTCCTG GCAGAGAACC AAAAATCACA GAACCCTAGT 
GACGTAGATT GTGTGGATAG ACTGGCGGAA GGTTACCTTG CTGTGGCCGT TGTCAGGAAA 
TCAGATGCCG ATCTCACCTG GAACACTCTG AGAGGCAGGA AGTCCTGCCA CACTGCTGTG 
GGCAGGACTG CAGGCTGGAA CATCCCCATG GGCCTGCTCT TCAACCAGTT AGGCTCCTGC 
AAATTTGATG AATTCTTTAG CCAGAGCTGT GCCCCTGGGG CCGACCCGAA GTCCAGTCTC 
TGCGCACTGT GCATTGGTGA CGAGAAGGGT GAGAACAAGT GTGCGCCCAA CAATAGTGAG 
AGATACTTTG GCTACACCGG GGCTTTCAGG TGCCTGGCAG AGAAGGCTGG AGATGTCGCA 
TTTGTGAGAG ATTCCACTAT CTTGCAGAAC ACAAACGGAG GGAACCCTGA GCCATGGGCC 
AGGGATTTGA AGCTGGAGGA CTTTGAGCTG CTGTGTCTTG ATGGCACCCG GCAGCCTGTG 
ACAAAGGCTC GGAGATGTCA CCTGGCCATG GCTCCGAACC ATGCTGTGGT ATCTCGGGAA 
GAAAAGGCCG AACACCTGAA GCAGGTGCTG CTCCTCCAGC AGACGCGGTT TGGAAGAAAT 
GGAACCAAAT GCCCAAGCGA GTTTTGCTTG TTCCAGTCTG AAACCAAAAA TCTTCTGTTC 
AATGACAACA CTGAGTGTCT GGCCAAACTC CAAGGCAAAA ACACATATGA AGAATATTTG 
GGATCAGCCT ATGTCACGGC CGTTGCTAAT CTGAGACAGT GTTCAGCCTC CCCGCTTCTG 
GAAGCCTGCG CCTTCCTGAG GAGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Analysis of new lactotransferrin gene variants in a case-control study related to periodontal disease in dog.
Molecular biology reports39(4)4673-81(2012 Apr)
Morinha F,Albuquerque C,Requicha J,Dias I,Leit?o J,Gut I,Guedes-Pinto H,Viegas C,Bastos E

Lactoferrin from canine neutrophils: isolation and physicochemical and antimicrobial properties.
Biochemistry. Biokhimiia72(4)445-51(2007 Apr)
Berlov MN,Korableva ES,Andreeva YV,Ovchinnikova TV,Kokryakov VN

Lactoferrin expression in the canine uterus during the estrous cycle and with pyometra.
Theriogenology66(5)1325-33(2006 Sep)
Kida K,Baba E,Torii R,Kawate N,Hatoya S,Wijewardana V,Sugiura K,Sawada T,Tamada H,Inaba T

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LTF cDNA ORF clone, Canis lupus familiaris(dog)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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