Gene Symbol | PODXL |
Entrez Gene ID | 482252 |
Full Name | podocalyxin like |
Synonyms | Gp135,PC,PCLP,PCLP-1,PCLP1,cPCLP1 |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(dog) |
ORF » Species Summary » Canis lupus familiaris » PODXL cDNA ORF clone
Gene Symbol | PODXL |
Entrez Gene ID | 482252 |
Full Name | podocalyxin like |
Synonyms | Gp135,PC,PCLP,PCLP-1,PCLP1,cPCLP1 |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(dog) |
mRNA | Protein | Name |
---|---|---|
NM_001020809.1 | NP_001018645.1 | podocalyxin precursor |
Galectin-8 regulates targeting of Gp135/podocalyxin and lumen formation at the apical surface of renal epithelial cells.
Lim H, Yu CY, Jou TS
FASEB journal : official publication of the Federation of American Societies for Experimental Biology31(11)4917-4927(2017 Nov)
A bipartite signal regulates the faithful delivery of apical domain marker podocalyxin/Gp135.
Yu CY, Chen JY, Lin YY, Shen KF, Lin WL, Chien CL, ter Beest MB, Jou TS
Molecular biology of the cell18(5)1710-22(2007 May)
Molecular identification of canine podocalyxin-like protein 1 as a renal tubulogenic regulator.
Cheng HY, Lin YY, Yu CY, Chen JY, Shen KF, Lin WL, Liao HK, Chen YJ, Liu CH, Pang VF, Jou TS
Journal of the American Society of Nephrology : JASN16(6)1612-22(2005 Jun)
Gp135/podocalyxin and NHERF-2 participate in the formation of a preapical domain during polarization of MDCK cells.
Meder D, Shevchenko A, Simons K, F?llekrug J
The Journal of cell biology168(2)303-13(2005 Jan)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
results reveal a new role of Gal-8 in the development of luminal organs by regulating targeting of apical polarity protein Gp135
Title: Galectin-8 regulates targeting of Gp135/podocalyxin and lumen formation at the apical surface of renal epithelial cells.
correct apical sorting of podocalyxin depends on a bipartite signal composed of an extracellular O-glycosylation-rich region and the intracellular PDZ domain-binding motif
Title: A bipartite signal regulates the faithful delivery of apical domain marker podocalyxin/Gp135.
The following PODXL gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PODXL cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCe00216 | |
Clone ID Related Accession (Same CDS sequence) | NM_001020809.1 | |
Accession Version | NM_001020809.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1716bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-16 | |
Organism | Canis lupus familiaris(dog) | |
Product | podocalyxin precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY970669.1. On or before May 25, 2005 this sequence version replaced XM_539371.1, XM_539372.1. ##Evidence-Data-START## Transcript exon combination :: AY970669.1 [ECO:0000332] ##Evidence-Data-END## |
1 | ATGCGCCCCG CGCCGCCGCC GCCGCTGCTG CTGCTGCTGC TGCTGCTGCC GCCGCCGTCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001018645.1 |
CDS | 7..1722 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001020809.1 |
1 | ATGCGCCCCG CGCCGCCGCC GCCGCTGCTG CTGCTGCTGC TGCTGCTGCC GCCGCCGTCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Galectin-8 regulates targeting of Gp135/podocalyxin and lumen formation at the apical surface of renal epithelial cells. |
A bipartite signal regulates the faithful delivery of apical domain marker podocalyxin/Gp135. |
Molecular identification of canine podocalyxin-like protein 1 as a renal tubulogenic regulator. |
Gp135/podocalyxin and NHERF-2 participate in the formation of a preapical domain during polarization of MDCK cells. |