Gene Symbol | DLA88 |
Entrez Gene ID | 474836 |
Full Name | MHC class I DLA-88 |
Synonyms | DLA-88 |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(dog) |
ORF » Species Summary » Canis lupus familiaris » DLA88 cDNA ORF clone
Gene Symbol | DLA88 |
Entrez Gene ID | 474836 |
Full Name | MHC class I DLA-88 |
Synonyms | DLA-88 |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(dog) |
mRNA | Protein | Name |
---|---|---|
XM_014118029.1 | XP_013973504.1 | MHC class I DLA-88 isoform X1 |
NM_001014767.1 | NP_001014767.1 | MHC class I DLA-88 precursor |
Canis lupus familiaris (dog) | DLA-64 | NP_001014400.1 |
Bos taurus (cattle) | BOLA-NC1 | NP_001099086.1 |
Danio rerio (zebrafish) | mhc1uka | XP_005159527.1 |
Danio rerio (zebrafish) | LOC101883648 | XP_005161941.1 |
Xenopus tropicalis (tropical clawed frog) | LOC100127707 | NP_001265363.1 |
Xenopus tropicalis (tropical clawed frog) | LOC100493954 | XP_002940102.2 |
Xenopus tropicalis (tropical clawed frog) | LOC100495225 | XP_002940109.2 |
Xenopus tropicalis (tropical clawed frog) | LOC100497446 | XP_004918996.1 |
Xenopus tropicalis (tropical clawed frog) | LOC100494770 | XP_002940106.1 |
Xenopus tropicalis (tropical clawed frog) | mhc1b2 | NP_001234924.1 |
Bos taurus (cattle) | BOLA-A | NP_001035644.1 |
Xenopus tropicalis (tropical clawed frog) | LOC100490553 | XP_002938999.2 |
Xenopus tropicalis (tropical clawed frog) | LOC100497122 | XP_004918998.1 |
Xenopus tropicalis (tropical clawed frog) | LOC100496024 | XP_002940114.2 |
Xenopus tropicalis (tropical clawed frog) | LOC101734387 | XP_004918994.1 |
Xenopus tropicalis (tropical clawed frog) | LOC100495382 | XP_002940110.1 |
Xenopus tropicalis (tropical clawed frog) | LOC100494618 | XP_002940105.1 |
Canis lupus familiaris (dog) | DLA-12 | NP_001014401.1 |
Bos taurus (cattle) | BOLA | NP_001033607.1 |
Bos taurus (cattle) | JSP.1 | NP_001035588.1 |
Danio rerio (zebrafish) | mhc1uba | NP_571546.1 |
Xenopus tropicalis (tropical clawed frog) | LOC100217322 | XP_004919447.1 |
Xenopus tropicalis (tropical clawed frog) | LOC100490896 | XP_002939001.2 |
Xenopus tropicalis (tropical clawed frog) | LOC100496639 | XP_002940118.2 |
Xenopus tropicalis (tropical clawed frog) | mr1 | XP_002940116.1 |
Xenopus tropicalis (tropical clawed frog) | LOC100496176 | XP_002940115.2 |
Xenopus tropicalis (tropical clawed frog) | LOC100494130 | XP_004918993.1 |
Xenopus tropicalis (tropical clawed frog) | LOC100494930 | XP_004918997.1 |
Xenopus tropicalis (tropical clawed frog) | LOC101730341 | XP_004919000.1 |
Xenopus tropicalis (tropical clawed frog) | LOC100490378 | XP_002938998.1 |
Xenopus tropicalis (tropical clawed frog) | LOC100487860 | XP_002944047.1 |
Xenopus tropicalis (tropical clawed frog) | LOC100494293 | XP_002940103.2 |
Xenopus tropicalis (tropical clawed frog) | LOC100495081 | XP_002940108.1 |
Xenopus tropicalis (tropical clawed frog) | LOC100494456 | XP_002940104.2 |
Homo sapiens (human) | HLA-B | NP_005505.2 |
Pan troglodytes (chimpanzee) | PATR-B | NP_001009081.1 |
MAMU-B18 | NP_001108436.1 | |
Canis lupus familiaris (dog) | DLA88 | NP_001014767.1 |
Danio rerio (zebrafish) | LOC796419 | XP_001336749.4 |
Xenopus tropicalis (tropical clawed frog) | hla-a | NP_001106536.1 |
Xenopus tropicalis (tropical clawed frog) | LOC100495868 | XP_002940113.1 |
Xenopus tropicalis (tropical clawed frog) | LOC100490728 | XP_002939000.1 |
Xenopus tropicalis (tropical clawed frog) | LOC100495703 | XP_002940112.2 |
Xenopus tropicalis (tropical clawed frog) | LOC100496488 | XP_002940117.2 |
Xenopus tropicalis (tropical clawed frog) | LOC100170421 | NP_001123671.1 |
Xenopus tropicalis (tropical clawed frog) | LOC100170569 | XP_004918999.1 |
Xenopus tropicalis (tropical clawed frog) | LOC100495542 | XP_002940111.1 |
Xenopus tropicalis (tropical clawed frog) | LOC100485167 | XP_002935389.2 |
Identification of novel polymorphisms and two distinct haplotype structures in dog leukocyte antigen class I genes: DLA-88, DLA-12 and DLA-64.
Miyamae J, Suzuki S, Katakura F, Uno S, Tanaka M, Okano M, Matsumoto T, Kulski JK, Moritomo T, Shiina T
Immunogenetics(2017 Sep)
Thirteen novel canine dog leukocyte antigen-88 alleles identified by sequence-based typing.
Venkataraman GM, Kennedy LJ, Little ME, Graves SS, Harkey MA, Torok-Storb BJ, Storb R
HLA90(3)165-170(2017 Sep)
Associations between gastric dilatation-volvulus in Great Danes and specific alleles of the canine immune-system genes DLA88, DRB1, and TLR5.
Harkey MA, Villagran AM, Venkataraman GM, Leisenring WM, Hullar MAJ, Torok-Storb BJ
American journal of veterinary research78(8)934-945(2017 Aug)
Diversified Anchoring Features the Peptide Presentation of DLA-88*50801: First Structural Insight into Domestic Dog MHC Class I.
Xiao J, Xiang W, Chai Y, Haywood J, Qi J, Ba L, Qi P, Wang M, Liu J, Gao GF
Journal of immunology (Baltimore, Md. : 1950)197(6)2306-15(2016 09)
Allelic diversity at the DLA-88 locus in Golden Retriever and Boxer breeds is limited.
Ross P, Buntzman AS, Vincent BG, Grover EN, Gojanovich GS, Collins EJ, Frelinger JA, Hess PR
Tissue antigens80(2)175-83(2012 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
associated with gastric dilatation-volvulus in Great Danes
Title: Associations between gastric dilatation-volvulus in Great Danes and specific alleles of the canine immune-system genes DLA88, DRB1, and TLR5.
determined the crystal structures of DLA-88*50801 complexed to the K11 and K9 peptides; DLA-88*50801 contains an unusual alpha2 helix with a large coil in the TCR contact region; Uncommon peptide anchoring modes and potential TCR-docking specificity of DLA-88*50801 are demonstrated
Title: Diversified Anchoring Features the Peptide Presentation of DLA-88*50801: First Structural Insight into Domestic Dog MHC Class I.
The following DLA88 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DLA88 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCe34186 | |
Clone ID Related Accession (Same CDS sequence) | NM_001014767.1 | |
Accession Version | NM_001014767.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1086bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-04-22 | |
Organism | Canis lupus familiaris(dog) | |
Product | MHC class I DLA-88 precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U55028.1. On Apr 8, 2005 this sequence version replaced XM_532066.1. ##Evidence-Data-START## Transcript exon combination :: M32283.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4547738, SAMEA4547744 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGAGGTGG TGATGCCGCG AGCCCTCCTC GTGCTGCTGT CGGCGGCCCT GGCCGTGACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001014767.1 |
CDS | 1..1086 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001014767.1 |
1 | ATGGAGGTGG TGATGCCGCG AGCCCTCCTC GTGCTGCTGT CGGCGGCCCT GGCCGTGACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCe39325 | |
Clone ID Related Accession (Same CDS sequence) | XM_014118029.1 | |
Accession Version | XM_014118029.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1038bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-09-16 | |
Organism | Canis lupus familiaris(Dog) | |
Product | MHC class I DLA-88 isoform X1 | |
Comment | MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003726081.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGAGGTGG TGATGCCGCG AGCCCTCCTC GTGCTGCTGT CGGCGGCCCT GGCCGTGACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_013973504.1 |
CDS | 65..1102 |
Translation |
Target ORF information:
Target ORF information:
|
XM_014118029.1 |
1 | ATGGAGGTGG TGATGCCGCG AGCCCTCCTC GTGCTGCTGT CGGCGGCCCT GGCCGTGACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Identification of novel polymorphisms and two distinct haplotype structures in dog leukocyte antigen class I genes: DLA-88, DLA-12 and DLA-64. |
Thirteen novel canine dog leukocyte antigen-88 alleles identified by sequence-based typing. |
Associations between gastric dilatation-volvulus in Great Danes and specific alleles of the canine immune-system genes DLA88, DRB1, and TLR5. |
Diversified Anchoring Features the Peptide Presentation of DLA-88*50801: First Structural Insight into Domestic Dog MHC Class I. |
Allelic diversity at the DLA-88 locus in Golden Retriever and Boxer breeds is limited. |