Gene Symbol | CXCL12 |
Entrez Gene ID | 449622 |
Full Name | C-X-C motif chemokine ligand 12 |
Synonyms | SDF1 |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(dog) |
ORF » Species Summary » Canis lupus familiaris » CXCL12 cDNA ORF clone
Gene Symbol | CXCL12 |
Entrez Gene ID | 449622 |
Full Name | C-X-C motif chemokine ligand 12 |
Synonyms | SDF1 |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(dog) |
mRNA | Protein | Name |
---|---|---|
NM_001128097.1 | NP_001121569.1 | stromal cell-derived factor 1 isoform 1 precursor |
NM_001308461.1 | NP_001295390.1 | stromal cell-derived factor 1 isoform 2 precursor |
Homo sapiens (human) | CXCL12 | NP_001171605.1 |
Rattus norvegicus (Norway rat) | Cxcl12 | NP_001029055.1 |
Mus musculus (house mouse) | Cxcl12 | NP_001012495.1 |
Gallus gallus (chicken) | CXCL12 | NP_989841.1 |
Bos taurus (cattle) | CXCL12 | NP_001106645.1 |
Pan troglodytes (chimpanzee) | LOC741624 | XP_001157443.2 |
CXCL12 | NP_001028106.1 | |
Canis lupus familiaris (dog) | CXCL12 | NP_001121569.1 |
Xenopus tropicalis (tropical clawed frog) | cxcl12 | NP_001015764.1 |
Interactions between CXCR4 and CXCL12 promote cell migration and invasion of canine hemangiosarcoma.
Im KS, Graef AJ, Breen M, Lindblad-Toh K, Modiano JF, Kim JH
Veterinary and comparative oncology15(2)315-327(2017 Jun)
Cloning and expression pattern of dog SDF-1 and the implications of altered expression of SDF-1 in ischemic myocardium.
Wei YJ, Tang Y, Li J, Cui CJ, Zhang H, Zhang XL, Zhang H, Hu SS
Cytokine40(1)52-9(2007 Oct)
Characterization of cDNA and genomic sequences encoding a canine chemokine receptor, CXCR4 and its ligand CXCL12.
Tsuchida S, Kagi A, Takahashi T
Veterinary immunology and immunopathology116(3-4)219-25(2007 Apr)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
interaction with CXCR4 to promote cell migration and invasion of hemangiosarcoma
Title: Interactions between CXCR4 and CXCL12 promote cell migration and invasion of canine hemangiosarcoma.
The temporally and differentially distributed pattern of SDF-1 expression between infarct area and border zone of myocardium should be beneficial to mobilization and homing of stem cells into the ischemic area to regenerate the damaged heart.
Title: Cloning and expression pattern of dog SDF-1 and the implications of altered expression of SDF-1 in ischemic myocardium.
A single nucleotide polymorphism (SNP) with synonymous substitution was observed in the exon of the CXCL12 gene.
Title: Characterization of cDNA and genomic sequences encoding a canine chemokine receptor, CXCR4 and its ligand CXCL12.
The following CXCL12 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CXCL12 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCe33650 | |
Clone ID Related Accession (Same CDS sequence) | NM_001128097.1 | |
Accession Version | NM_001128097.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 282bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-01-12 | |
Organism | Canis lupus familiaris(dog) | |
Product | stromal cell-derived factor 1 isoform 1 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DQ182701.1. On Jun 5, 2008 this sequence version replaced XM_844174.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: DQ182701.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103936001, SAMEA103936002 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGAACGCCA AGGTCGCCGC CGCGCTGGTC CTCGTGCTGA CTGCGCTGTG CCTCAGCCAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001121569.1 |
CDS | 6..287 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001128097.1 |
1 | ATGAACGCCA AGGTCGCCGC CGCGCTGGTC CTCGTGCTGA CTGCGCTGTG CCTCAGCCAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCe34325 | |
Clone ID Related Accession (Same CDS sequence) | NM_001308461.1 | |
Accession Version | NM_001308461.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 270bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-12-17 | |
Organism | Canis lupus familiaris(dog) | |
Product | stromal cell-derived factor 1 isoform 2 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DQ182700.1, AH014147.3, DN271893.1 and DN880217.1. Transcript Variant: This variant (2) differs in the 3' UTR and lacks a portion of the 3' coding region, compared to variant 1. It encodes isoform 2, which has a shorter C-terminus, compared to isoform 1. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA103936001, SAMEA103936002 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGAACGCCA AGGTCGCCGC CGCGCTGGTC CTCGTGCTGA CTGCGCTGTG CCTCAGCCAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001295390.1 |
CDS | 6..275 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001308461.1 |
1 | ATGAACGCCA AGGTCGCCGC CGCGCTGGTC CTCGTGCTGA CTGCGCTGTG CCTCAGCCAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Interactions between CXCR4 and CXCL12 promote cell migration and invasion of canine hemangiosarcoma. |
Cloning and expression pattern of dog SDF-1 and the implications of altered expression of SDF-1 in ischemic myocardium. |
Characterization of cDNA and genomic sequences encoding a canine chemokine receptor, CXCR4 and its ligand CXCL12. |