Gene Symbol | ELANE |
Entrez Gene ID | 442980 |
Full Name | elastase, neutrophil expressed |
Synonyms | ELA2 |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(dog) |
ORF » Species Summary » Canis lupus familiaris » ELANE cDNA ORF clone
Gene Symbol | ELANE |
Entrez Gene ID | 442980 |
Full Name | elastase, neutrophil expressed |
Synonyms | ELA2 |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(dog) |
mRNA | Protein | Name |
---|---|---|
NM_001003378.2 | NP_001003378.1 | neutrophil elastase precursor |
Hereditary neutropenia: dogs explain human neutrophil elastase mutations.
Horwitz M, Benson KF, Duan Z, Li FQ, Person RE
Trends in molecular medicine10(4)163-70(2004 Apr)
Cloning and sequencing of the canine neutrophil elastase cDNA.
Katen LJ, Aprikyan AG, Dale DC, Osborne WR
DNA sequence : the journal of DNA sequencing and mapping13(4)221-3(2002 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
neutrophil elastase mutations play a role in hereditary neutropenia, as shown in the dog model [review]
Title: Hereditary neutropenia: dogs explain human neutrophil elastase mutations.
The following ELANE gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ELANE cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCe33586 | |
Clone ID Related Accession (Same CDS sequence) | NM_001003378.2 | |
Accession Version | NM_001003378.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 849bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-10-21 | |
Organism | Canis lupus familiaris(dog) | |
Product | neutrophil elastase precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF494190.1. On Aug 30, 2012 this sequence version replaced NM_001003378.1. ##Evidence-Data-START## Transcript exon combination :: AF494190.1, DN365022.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN07419780, SAMN07419790 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGACCGCCC GCCGAGTGCC CGCCGGCCCT GCCCTGGGCC CACTGCTGCT GCTGGCCACG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001003378.1 |
CDS | 21..869 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001003378.2 |
1 | ATGACCGCCC GCCGAGTGCC CGCCGGCCCT GCCCTGGGCC CACTGCTGCT GCTGGCCACG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Hereditary neutropenia: dogs explain human neutrophil elastase mutations. |
Cloning and sequencing of the canine neutrophil elastase cDNA. |