PTGS2 cDNA ORF clone, Canis lupus familiaris(dog)

Gene
Clones
gRNAs

Summary

Gene Symbol	PTGS2
Entrez Gene ID	442942
Full Name	prostaglandin-endoperoxide synthase 2
Synonyms	COX-2
General protein information	Preferred Names prostaglandin-endoperoxide synthase 2 Names prostaglandin G/H synthase 2 cyclooxygenase 2 cyclooxygenase type 2 prostaglandin G/H synthase-2
Gene Type	protein-coding
Organism	Canis lupus familiaris(dog)

mRNA and Protein(s)

mRNA	Protein	Name
XM_005622227.2	XP_005622284.1	prostaglandin G/H synthase 2 isoform X1
XM_005622228.2	XP_005622285.1	prostaglandin G/H synthase 2 isoform X2
XM_005622227.3	XP_005622284.1	prostaglandin G/H synthase 2 isoform X1
NM_001003354.1	NP_001003354.1	prostaglandin G/H synthase 2 precursor

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	PTGS2	NP_001161191.1
Danio rerio (zebrafish)	ptgs2b	NP_001020675.1
Mus musculus (house mouse)	Ptgs2	NP_035328.2
Canis lupus familiaris (dog)	PTGS2	NP_001003354.1
Pan troglodytes (chimpanzee)	PTGS2	XP_524999.3
	PTGS2	XP_001107538.2
Rattus norvegicus (Norway rat)	Ptgs2	NP_058928.3
Homo sapiens (human)	PTGS2	NP_000954.1
Bos taurus (cattle)	PTGS2	NP_776870.1
Xenopus tropicalis (tropical clawed frog)	ptgs2	NP_001025697.1

Gene Ontology
Bibliography

Related articles in PubMed

Expression of iNOS, COX-2 and VEGF in canine mammary tumours and non-neoplastic mammary glands: Association with clinicopathological features and tumour grade.
Anadol E, Yar Saglam AS, Gultiken N, Karakas K, Alcigir E, Alkan H, Kanca H
Acta veterinaria Hungarica65(3)382-393(2017 09)

Low expression of cyclooxygenase-2 in chronic kidney disease in young dogs.
Yabuki A, Miyazaki A, Ichii O, Kohyama M, Sawa M, Yamato O
Research in veterinary science10971-73(2016 Dec)

Activation of MEK/ERK pathways through NF-?B activation is involved in interleukin-1?-induced cyclooxygenease-2 expression in canine dermal fibroblasts.
Tsuchiya H, Nakano R, Konno T, Okabayashi K, Narita T, Sugiya H
Veterinary immunology and immunopathology168(3-4)223-32(2015 Dec)

Immunohistochemical expression of cyclooxygenase-2 in normal, hyperplastic and neoplastic canine lymphoid tissues.
Asproni P, Vignoli M, Cancedda S, Millanta F, Terragni R, Poli A
Journal of comparative pathology151(1)35-41(2014 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Increased iNOS, COX-2 and VEGF gene mRNA levels were found to be related with the histological grade of malignancy in dogs with mammary tumours.
Title: Expression of iNOS, COX-2 and VEGF in canine mammary tumours and non-neoplastic mammary glands: Association with clinicopathological features and tumour grade.

These findings demonstrate low renal COX-2 expression in CKD in young dogs, but whether this is correlated with disease pathogenesis remains unclear.
Title: Low expression of cyclooxygenase-2 in chronic kidney disease in young dogs.

These findings suggest that stimulation of MEK/ERK signaling pathway by NF-kappaB activation regulates IL-1beta-induced COX-2 expression and subsequent prostaglandin E2 release in canine dermal fibroblasts.
Title: Activation of MEK/ERK pathways through NF-?B activation is involved in interleukin-1?-induced cyclooxygenease-2 expression in canine dermal fibroblasts.

provide a rationale for further investigation of COX-2 expression in canine lymphoma for prognostic, chemopreventive and chemotherapeutic purposes
Title: Immunohistochemical expression of cyclooxygenase-2 in normal, hyperplastic and neoplastic canine lymphoid tissues.

The results suggest that mPGES1 is involved in the regulation of RBF when Na(+) intake is low and that the renal effects elicited by mPGES1 inhibition are modulated by a compensatory increment in PGI2.
Title: Renal effects induced by prolonged mPGES1 inhibition.

The following PTGS2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PTGS2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OCe00245	NM_001003354.1 Latest version!	Canis lupus familiaris prostaglandin-endoperoxide synthase 2 (PTGS2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00
OCe08926	XM_005622227.3 Latest version!	Canis lupus familiaris prostaglandin-endoperoxide synthase 2 (PTGS2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00
OCe08927	XM_005622228.2 Latest version!	Canis lupus familiaris prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (PTGS2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00
View Old Accession Versions >>
OCe08926	XM_005622227.2	Canis lupus familiaris prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (PTGS2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PTGS2 ( NM_001003354.1 ) cDNA ORF clone, Canis lupus familiaris(dog) -> NP_001003354.1 Canis lupus familiaris prostaglandin-endoperoxide synthase 2 (PTGS2), mRNA.

Price & Availability↑

CloneID	OCe00245
Clone ID Related Accession (Same CDS sequence)	NM_001003354.1
Accession Version	NM_001003354.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1815bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-13
Organism	Canis lupus familiaris(dog)
Product	prostaglandin G/H synthase 2 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY044905.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY044905.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00013638, SAMN00991611 [ECO:0000350] ##Evidence-Data-END##

ATGCTGGCCC GCGCCCTGGT GCTCTGCGCC GCCCTGGCGG TCGTCCGCGC AGCAAATCCT 
TGCTGTTCCC ACCCATGTCA AAACCAAGGT ATTTGTATGA GCACAGGATT TGACCAGTAT 
AAGTGTGACT GTACCCGAAC AGGATTCTAC GGCGAAAACT GCTCAACACC GGAATTTCTG 
ACAAGAATAA AATTATACCT GAAACCCACT CCAAATACAG TACACTACAT ACTTACCCAC 
TTCAAGGGAG TCTGGAACAT TGTCAATAAC ATCCCCTTCC TGCGAAATAC AATTATGAAA 
TATGTGTTGA CATCCCGGTC ACATTTGATT GAGAGTCCAC CAACTTATAA TGTGAACTAC 
GGCTATAAAA GCTGGGAAGC CTTTTCTAAC CTCTCCTATT ATACCAGAGC TCTTCCCCCT 
GTACCTGATG ACTGTCCAAC ACCCATGGGT GTGAAAGGCA AGAAAGAGCT TCCTGATTCA 
AAAGAGATTG TGGAAAAGTT TCTTCTGCGA AGAAAGTTCA TTCCTGATCC CCAAGGCACC 
AATATGATGT TTGCATTCTT TGCCCAGCAC TTTACCCATC AATTTTTCAA GACAGATCAT 
AAGCGAGGAC CAGCTTTCAC CAAAGGATTG GGCCATGGGG TGGACTTAAA TCATGTTTAT 
GGGGAAACTT TGGATAGACA ACATAAACTG CGCCTTTTCA AGGATGGAAA AATGAAATAT 
CAGGTAATTG ATGGAGAGGT GTATCCTCCT ACCGTCAAAG ATACTCAGGT CGAGATGATC 
TACCCACCTC ATGTTCCTGA ACACCTGCAG TTTGCTGTGG GCCAGGAGGT CTTTGGTCTG 
GTGCCTGGTC TGATGATGTA TGCCACCATT TGGCTGCGGG AGCATAACAG AGTGTGTGAT 
GTGCTTAAAC AGGAGCACCC AGAATGGGAT GATGAGCGGT TATTCCAGAC GAGCAGGCTA 
ATACTTATAG GAGAAACCAT TAAGATTGTG ATTGAAGACT ATGTACAACA CTTGAGTGGC 
TATCACTTCA AGCTGAAGTT TGACCCAGAG CTGCTTTTCA ACCAACAATT CCAGTACCAA 
AACCGCATTG CTGCTGAGTT TAACACACTC TACCACTGGC ATCCCCTCCT GCCTGACACC 
TTGCAAATAG ATGACCAGGA GTACAATTTC CAACAGTTTA TCTACAACAA CTCTATATTA 
TTGGAACATG GCCTTACCCA GTTTGTGGAA TCATTCAGCA GGCAAATTGC TGGCAGGGTT 
GCCGGTGGCA GGAATGTTCC AGCTGCAGTA CAACAAGTAG CAAAAGCTTC GATTGACCAG 
AGCAGACAGA TGAAATACCA GTCTCTTAAT GAGTATCGCA AACGCTTTAG GCTGAAGCCC 
TATACATCAT TCGAAGAACT TACAGGAGAG AAGGAAATGG CTGCGGGGTT GGAGGCCCTT 
TATGGTGATA TTGATGCCAT GGAGCTGTAT CCTGCCCTCT TGGTAGAAAA GCCTCGTCCA 
GATGCCATCT TTGGTGAGAC CATGGTAGAA ATGGGAGCAC CATTCTCCTT GAAAGGACTT 
ATGGGTAATC CCATCTGTTC ACCTGACTAC TGGAAGCCTA GCACCTTTGG TGGAGAAGTA 
GGCTTTAAAA TCATCAACAC TGCCTCAATC CAGTCTCTCA TCTGCAATAA CGTGAAGGGC 
TGTCCATTCA CTGCATTCTC TGTTCAAGAC GGACAACTCA CCAAAACAGT CACCATTAAT 
GCAAGCTCTT CGCACTCCGG TCTAGATGAC ATCAATCCCA CAGTCCTACT GAAAGAACGG 
TCAACTGAAC TATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001003354.1
CDS	29..1843
Translation	MLARALVLCAALAVVRAANPCCSHPCQNQGICMSTGFDQYKCDCTRTGFYGENCSTPEFLTRIKLYLKPTPNTVHYILTHFKGVWNIVNNIPFLRNTIMKYVLTSRSHLIESPPTYNVNYGYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGKKELPDSKEIVEKFLLRRKFIPDPQGTNMMFAFFAQHFTHQFFKTDHKRGPAFTKGLGHGVDLNHVYGETLDRQHKLRLFKDGKMKYQVIDGEVYPPTVKDTQVEMIYPPHVPEHLQFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWDDERLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDTLQIDDQEYNFQQFIYNNSILLEHGLTQFVESFSRQIAGRVAGGRNVPAAVQQVAKASIDQSRQMKYQSLNEYRKRFRLKPYTSFEELTGEKEMAAGLEALYGDIDAMELYPALLVEKPRPDAIFGETMVEMGAPFSLKGLMGNPICSPDYWKPSTFGGEVGFKIINTASIQSLICNNVKGCPFTAFSVQDGQLTKTVTINASSSHSGLDDINPTVLLKERSTEL

Target ORF information:

RefSeq Version	NM_001003354.1
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris prostaglandin-endoperoxide synthase 2 (PTGS2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001003354.1

ORF Insert Sequence:

ATGCTGGCCC GCGCCCTGGT GCTCTGCGCC GCCCTGGCGG TCGTCCGCGC AGCAAATCCT 
TGCTGTTCCC ACCCATGTCA AAACCAAGGT ATTTGTATGA GCACAGGATT TGACCAGTAT 
AAGTGTGACT GTACCCGAAC AGGATTCTAC GGCGAAAACT GCTCAACACC GGAATTTCTG 
ACAAGAATAA AATTATACCT GAAACCCACT CCAAATACAG TACACTACAT ACTTACCCAC 
TTCAAGGGAG TCTGGAACAT TGTCAATAAC ATCCCCTTCC TGCGAAATAC AATTATGAAA 
TATGTGTTGA CATCCCGGTC ACATTTGATT GAGAGTCCAC CAACTTATAA TGTGAACTAC 
GGCTATAAAA GCTGGGAAGC CTTTTCTAAC CTCTCCTATT ATACCAGAGC TCTTCCCCCT 
GTACCTGATG ACTGTCCAAC ACCCATGGGT GTGAAAGGCA AGAAAGAGCT TCCTGATTCA 
AAAGAGATTG TGGAAAAGTT TCTTCTGCGA AGAAAGTTCA TTCCTGATCC CCAAGGCACC 
AATATGATGT TTGCATTCTT TGCCCAGCAC TTTACCCATC AATTTTTCAA GACAGATCAT 
AAGCGAGGAC CAGCTTTCAC CAAAGGATTG GGCCATGGGG TGGACTTAAA TCATGTTTAT 
GGGGAAACTT TGGATAGACA ACATAAACTG CGCCTTTTCA AGGATGGAAA AATGAAATAT 
CAGGTAATTG ATGGAGAGGT GTATCCTCCT ACCGTCAAAG ATACTCAGGT CGAGATGATC 
TACCCACCTC ATGTTCCTGA ACACCTGCAG TTTGCTGTGG GCCAGGAGGT CTTTGGTCTG 
GTGCCTGGTC TGATGATGTA TGCCACCATT TGGCTGCGGG AGCATAACAG AGTGTGTGAT 
GTGCTTAAAC AGGAGCACCC AGAATGGGAT GATGAGCGGT TATTCCAGAC GAGCAGGCTA 
ATACTTATAG GAGAAACCAT TAAGATTGTG ATTGAAGACT ATGTACAACA CTTGAGTGGC 
TATCACTTCA AGCTGAAGTT TGACCCAGAG CTGCTTTTCA ACCAACAATT CCAGTACCAA 
AACCGCATTG CTGCTGAGTT TAACACACTC TACCACTGGC ATCCCCTCCT GCCTGACACC 
TTGCAAATAG ATGACCAGGA GTACAATTTC CAACAGTTTA TCTACAACAA CTCTATATTA 
TTGGAACATG GCCTTACCCA GTTTGTGGAA TCATTCAGCA GGCAAATTGC TGGCAGGGTT 
GCCGGTGGCA GGAATGTTCC AGCTGCAGTA CAACAAGTAG CAAAAGCTTC GATTGACCAG 
AGCAGACAGA TGAAATACCA GTCTCTTAAT GAGTATCGCA AACGCTTTAG GCTGAAGCCC 
TATACATCAT TCGAAGAACT TACAGGAGAG AAGGAAATGG CTGCGGGGTT GGAGGCCCTT 
TATGGTGATA TTGATGCCAT GGAGCTGTAT CCTGCCCTCT TGGTAGAAAA GCCTCGTCCA 
GATGCCATCT TTGGTGAGAC CATGGTAGAA ATGGGAGCAC CATTCTCCTT GAAAGGACTT 
ATGGGTAATC CCATCTGTTC ACCTGACTAC TGGAAGCCTA GCACCTTTGG TGGAGAAGTA 
GGCTTTAAAA TCATCAACAC TGCCTCAATC CAGTCTCTCA TCTGCAATAA CGTGAAGGGC 
TGTCCATTCA CTGCATTCTC TGTTCAAGAC GGACAACTCA CCAAAACAGT CACCATTAAT 
GCAAGCTCTT CGCACTCCGG TCTAGATGAC ATCAATCCCA CAGTCCTACT GAAAGAACGG 
TCAACTGAAC TATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PTGS2 ( XM_005622227.2 ) cDNA ORF clone, Canis lupus familiaris(dog) -> XP_005622284.1 Canis lupus familiaris prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (PTGS2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OCe08926
Clone ID Related Accession (Same CDS sequence)	XM_005622227.2 , XM_005622227.3
Accession Version	XM_005622227.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1815bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-09-16
Organism	Canis lupus familiaris(Dog)
Product	prostaglandin G/H synthase 2 isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003726067.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 17, 2015 this sequence version replaced XM_005622227.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGGCCC GCGCCCTGGT GCTCTGCGCC GCCCTGGCGG TCGTCCGCGC AGCAAATCCT 
TGCTGTTCCC ACCCATGTCA AAACCAAGGT ATTTGTATGA GCACAGGATT TGACCAGTAT 
AAGTGTGACT GTACCCGAAC AGGATTCTAC GGCGAAAACT GCTCAACACC GGAATTTCTG 
ACAAGAATAA AATTATACCT GAAACCCACT CCAAATACAG TACACTACAT ACTTACCCAC 
TTCAAGGGAG TCTGGAACAT TGTCAATAAC ATCCCCTTCC TGCGAAATAC AATTATGAAA 
TATGTGTTGA CATCCCGGTC ACATTTGATT GAGAGTCCAC CAACTTATAA TGTGAACTAC 
GGCTATAAAA GCTGGGAAGC CTTTTCTAAC CTCTCCTATT ATACCAGAGC TCTTCCCCCT 
GTACCTGATG ACTGTCCAAC ACCCATGGGT GTGAAAGGCA AGAAAGAGCT TCCTGATTCA 
AAAGAGATTG TGGAAAAGTT TCTTCTGCGA AGAAAGTTCA TTCCTGATCC CCAAGGCACC 
AATATGATGT TTGCATTCTT TGCCCAGCAC TTTACCCATC AATTTTTCAA GACAGATCAT 
AAGCGAGGAC CAGCTTTCAC CAAAGGATTG GGCCATGGGG TGGACTTAAA TCATGTTTAT 
GGGGAAACTT TGGATAGACA ACATAAACTG CGCCTTTTCA AGGATGGAAA AATGAAATAT 
CAGGTAATTG ATGGAGAGGT GTATCCTCCT ACCGTCAAAG ATACTCAGGT CGAGATGATC 
TACCCACCTC ATGTTCCTGA ACACCTGCAG TTTGCTGTGG GCCAGGAGGT CTTTGGTCTG 
GTGCCTGGTC TGATGATGTA TGCCACCATT TGGCTGCGGG AGCATAACAG AGTGTGTGAT 
GTGCTTAAAC AGGAGCACCC AGAATGGGAT GATGAGCGGT TATTCCAGAC GAGCAGGCTA 
ATACTGATAG GAGAAACCAT TAAGATTGTG ATTGAAGACT ATGTACAACA CTTGAGTGGC 
TATCACTTCA AGCTGAAGTT TGACCCAGAG CTGCTTTTCA ACCAACAATT CCAGTACCAA 
AACCGCATTG CTGCTGAGTT TAACACACTC TACCACTGGC ATCCCCTCCT GCCTGACACC 
TTGCAAATAG ATGACCAGGA GTACAATTTC CAACAGTTTA TCTACAACAA CTCTATATTA 
TTGGAACATG GCCTTACCCA GTTTGTGGAA TCATTCAGCA GGCAAATTGC TGGCAGGGTT 
GCCGGTGGCA GGAATGTTCC AGCTGCAGTA CAACAAGTAG CAAAAGCTTC GATTGACCAG 
AGCAGACAGA TGAAATACCA GTCTCTTAAT GAGTATCGCA AACGCTTTAG GCTGAAGCCC 
TATACATCAT TCGAAGAACT TACAGGAGAG AAGGAAATGG CTGCGGGGTT GGAGGCCCTT 
TATGGTGATA TTGATGCCAT GGAGCTGTAT CCTGCCCTCT TGGTAGAAAA GCCTCGTCCA 
GATGCCATCT TTGGTGAGAC CATGGTAGAA ATGGGAGCAC CATTCTCCTT GAAAGGACTT 
ATGGGTAATC CCATCTGTTC ACCTGACTAC TGGAAGCCTA GCACCTTTGG TGGAGAAGTA 
GGCTTTAAAA TCATCAACAC TGCCTCAATC CAGTCTCTCA TCTGCAATAA CGTGAAGGGC 
TGTCCATTCA CTGCATTCTC TGTTCAAGAC GGACAACTCA CCAAAACAGT CACCATTAAT 
GCAAGCTCTT CGCACTCCGG TCTAGATGAC ATCAATCCCA CAGTCCTACT GAAAGAACGG 
TCAACTGAAC TATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005622284.1
CDS	200..2014
Translation	MLARALVLCAALAVVRAANPCCSHPCQNQGICMSTGFDQYKCDCTRTGFYGENCSTPEFLTRIKLYLKPTPNTVHYILTHFKGVWNIVNNIPFLRNTIMKYVLTSRSHLIESPPTYNVNYGYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGKKELPDSKEIVEKFLLRRKFIPDPQGTNMMFAFFAQHFTHQFFKTDHKRGPAFTKGLGHGVDLNHVYGETLDRQHKLRLFKDGKMKYQVIDGEVYPPTVKDTQVEMIYPPHVPEHLQFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWDDERLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDTLQIDDQEYNFQQFIYNNSILLEHGLTQFVESFSRQIAGRVAGGRNVPAAVQQVAKASIDQSRQMKYQSLNEYRKRFRLKPYTSFEELTGEKEMAAGLEALYGDIDAMELYPALLVEKPRPDAIFGETMVEMGAPFSLKGLMGNPICSPDYWKPSTFGGEVGFKIINTASIQSLICNNVKGCPFTAFSVQDGQLTKTVTINASSSHSGLDDINPTVLLKERSTEL

Target ORF information:

RefSeq Version	XM_005622227.2
Organism	Canis lupus familiaris(Dog)
Definition	Canis lupus familiaris prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (PTGS2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005622227.2

ORF Insert Sequence:

ATGCTGGCCC GCGCCCTGGT GCTCTGCGCC GCCCTGGCGG TCGTCCGCGC AGCAAATCCT 
TGCTGTTCCC ACCCATGTCA AAACCAAGGT ATTTGTATGA GCACAGGATT TGACCAGTAT 
AAGTGTGACT GTACCCGAAC AGGATTCTAC GGCGAAAACT GCTCAACACC GGAATTTCTG 
ACAAGAATAA AATTATACCT GAAACCCACT CCAAATACAG TACACTACAT ACTTACCCAC 
TTCAAGGGAG TCTGGAACAT TGTCAATAAC ATCCCCTTCC TGCGAAATAC AATTATGAAA 
TATGTGTTGA CATCCCGGTC ACATTTGATT GAGAGTCCAC CAACTTATAA TGTGAACTAC 
GGCTATAAAA GCTGGGAAGC CTTTTCTAAC CTCTCCTATT ATACCAGAGC TCTTCCCCCT 
GTACCTGATG ACTGTCCAAC ACCCATGGGT GTGAAAGGCA AGAAAGAGCT TCCTGATTCA 
AAAGAGATTG TGGAAAAGTT TCTTCTGCGA AGAAAGTTCA TTCCTGATCC CCAAGGCACC 
AATATGATGT TTGCATTCTT TGCCCAGCAC TTTACCCATC AATTTTTCAA GACAGATCAT 
AAGCGAGGAC CAGCTTTCAC CAAAGGATTG GGCCATGGGG TGGACTTAAA TCATGTTTAT 
GGGGAAACTT TGGATAGACA ACATAAACTG CGCCTTTTCA AGGATGGAAA AATGAAATAT 
CAGGTAATTG ATGGAGAGGT GTATCCTCCT ACCGTCAAAG ATACTCAGGT CGAGATGATC 
TACCCACCTC ATGTTCCTGA ACACCTGCAG TTTGCTGTGG GCCAGGAGGT CTTTGGTCTG 
GTGCCTGGTC TGATGATGTA TGCCACCATT TGGCTGCGGG AGCATAACAG AGTGTGTGAT 
GTGCTTAAAC AGGAGCACCC AGAATGGGAT GATGAGCGGT TATTCCAGAC GAGCAGGCTA 
ATACTGATAG GAGAAACCAT TAAGATTGTG ATTGAAGACT ATGTACAACA CTTGAGTGGC 
TATCACTTCA AGCTGAAGTT TGACCCAGAG CTGCTTTTCA ACCAACAATT CCAGTACCAA 
AACCGCATTG CTGCTGAGTT TAACACACTC TACCACTGGC ATCCCCTCCT GCCTGACACC 
TTGCAAATAG ATGACCAGGA GTACAATTTC CAACAGTTTA TCTACAACAA CTCTATATTA 
TTGGAACATG GCCTTACCCA GTTTGTGGAA TCATTCAGCA GGCAAATTGC TGGCAGGGTT 
GCCGGTGGCA GGAATGTTCC AGCTGCAGTA CAACAAGTAG CAAAAGCTTC GATTGACCAG 
AGCAGACAGA TGAAATACCA GTCTCTTAAT GAGTATCGCA AACGCTTTAG GCTGAAGCCC 
TATACATCAT TCGAAGAACT TACAGGAGAG AAGGAAATGG CTGCGGGGTT GGAGGCCCTT 
TATGGTGATA TTGATGCCAT GGAGCTGTAT CCTGCCCTCT TGGTAGAAAA GCCTCGTCCA 
GATGCCATCT TTGGTGAGAC CATGGTAGAA ATGGGAGCAC CATTCTCCTT GAAAGGACTT 
ATGGGTAATC CCATCTGTTC ACCTGACTAC TGGAAGCCTA GCACCTTTGG TGGAGAAGTA 
GGCTTTAAAA TCATCAACAC TGCCTCAATC CAGTCTCTCA TCTGCAATAA CGTGAAGGGC 
TGTCCATTCA CTGCATTCTC TGTTCAAGAC GGACAACTCA CCAAAACAGT CACCATTAAT 
GCAAGCTCTT CGCACTCCGG TCTAGATGAC ATCAATCCCA CAGTCCTACT GAAAGAACGG 
TCAACTGAAC TATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PTGS2 ( XM_005622227.3 ) cDNA ORF clone, Canis lupus familiaris(dog) -> XP_005622284.1 Canis lupus familiaris prostaglandin-endoperoxide synthase 2 (PTGS2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OCe08926
Clone ID Related Accession (Same CDS sequence)	XM_005622227.2 , XM_005622227.3
Accession Version	XM_005622227.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1815bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-04
Organism	Canis lupus familiaris(dog)
Product	prostaglandin G/H synthase 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006589.3) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 5, 2017 this sequence version replaced XM_005622227.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGGCCC GCGCCCTGGT GCTCTGCGCC GCCCTGGCGG TCGTCCGCGC AGCAAATCCT 
TGCTGTTCCC ACCCATGTCA AAACCAAGGT ATTTGTATGA GCACAGGATT TGACCAGTAT 
AAGTGTGACT GTACCCGAAC AGGATTCTAC GGCGAAAACT GCTCAACACC GGAATTTCTG 
ACAAGAATAA AATTATACCT GAAACCCACT CCAAATACAG TACACTACAT ACTTACCCAC 
TTCAAGGGAG TCTGGAACAT TGTCAATAAC ATCCCCTTCC TGCGAAATAC AATTATGAAA 
TATGTGTTGA CATCCCGGTC ACATTTGATT GAGAGTCCAC CAACTTATAA TGTGAACTAC 
GGCTATAAAA GCTGGGAAGC CTTTTCTAAC CTCTCCTATT ATACCAGAGC TCTTCCCCCT 
GTACCTGATG ACTGTCCAAC ACCCATGGGT GTGAAAGGCA AGAAAGAGCT TCCTGATTCA 
AAAGAGATTG TGGAAAAGTT TCTTCTGCGA AGAAAGTTCA TTCCTGATCC CCAAGGCACC 
AATATGATGT TTGCATTCTT TGCCCAGCAC TTTACCCATC AATTTTTCAA GACAGATCAT 
AAGCGAGGAC CAGCTTTCAC CAAAGGATTG GGCCATGGGG TGGACTTAAA TCATGTTTAT 
GGGGAAACTT TGGATAGACA ACATAAACTG CGCCTTTTCA AGGATGGAAA AATGAAATAT 
CAGGTAATTG ATGGAGAGGT GTATCCTCCT ACCGTCAAAG ATACTCAGGT CGAGATGATC 
TACCCACCTC ATGTTCCTGA ACACCTGCAG TTTGCTGTGG GCCAGGAGGT CTTTGGTCTG 
GTGCCTGGTC TGATGATGTA TGCCACCATT TGGCTGCGGG AGCATAACAG AGTGTGTGAT 
GTGCTTAAAC AGGAGCACCC AGAATGGGAT GATGAGCGGT TATTCCAGAC GAGCAGGCTA 
ATACTGATAG GAGAAACCAT TAAGATTGTG ATTGAAGACT ATGTACAACA CTTGAGTGGC 
TATCACTTCA AGCTGAAGTT TGACCCAGAG CTGCTTTTCA ACCAACAATT CCAGTACCAA 
AACCGCATTG CTGCTGAGTT TAACACACTC TACCACTGGC ATCCCCTCCT GCCTGACACC 
TTGCAAATAG ATGACCAGGA GTACAATTTC CAACAGTTTA TCTACAACAA CTCTATATTA 
TTGGAACATG GCCTTACCCA GTTTGTGGAA TCATTCAGCA GGCAAATTGC TGGCAGGGTT 
GCCGGTGGCA GGAATGTTCC AGCTGCAGTA CAACAAGTAG CAAAAGCTTC GATTGACCAG 
AGCAGACAGA TGAAATACCA GTCTCTTAAT GAGTATCGCA AACGCTTTAG GCTGAAGCCC 
TATACATCAT TCGAAGAACT TACAGGAGAG AAGGAAATGG CTGCGGGGTT GGAGGCCCTT 
TATGGTGATA TTGATGCCAT GGAGCTGTAT CCTGCCCTCT TGGTAGAAAA GCCTCGTCCA 
GATGCCATCT TTGGTGAGAC CATGGTAGAA ATGGGAGCAC CATTCTCCTT GAAAGGACTT 
ATGGGTAATC CCATCTGTTC ACCTGACTAC TGGAAGCCTA GCACCTTTGG TGGAGAAGTA 
GGCTTTAAAA TCATCAACAC TGCCTCAATC CAGTCTCTCA TCTGCAATAA CGTGAAGGGC 
TGTCCATTCA CTGCATTCTC TGTTCAAGAC GGACAACTCA CCAAAACAGT CACCATTAAT 
GCAAGCTCTT CGCACTCCGG TCTAGATGAC ATCAATCCCA CAGTCCTACT GAAAGAACGG 
TCAACTGAAC TATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005622284.1
CDS	56..1870
Translation	MLARALVLCAALAVVRAANPCCSHPCQNQGICMSTGFDQYKCDCTRTGFYGENCSTPEFLTRIKLYLKPTPNTVHYILTHFKGVWNIVNNIPFLRNTIMKYVLTSRSHLIESPPTYNVNYGYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGKKELPDSKEIVEKFLLRRKFIPDPQGTNMMFAFFAQHFTHQFFKTDHKRGPAFTKGLGHGVDLNHVYGETLDRQHKLRLFKDGKMKYQVIDGEVYPPTVKDTQVEMIYPPHVPEHLQFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWDDERLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDTLQIDDQEYNFQQFIYNNSILLEHGLTQFVESFSRQIAGRVAGGRNVPAAVQQVAKASIDQSRQMKYQSLNEYRKRFRLKPYTSFEELTGEKEMAAGLEALYGDIDAMELYPALLVEKPRPDAIFGETMVEMGAPFSLKGLMGNPICSPDYWKPSTFGGEVGFKIINTASIQSLICNNVKGCPFTAFSVQDGQLTKTVTINASSSHSGLDDINPTVLLKERSTEL

Target ORF information:

RefSeq Version	XM_005622227.3
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris prostaglandin-endoperoxide synthase 2 (PTGS2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005622227.3

ORF Insert Sequence:

ATGCTGGCCC GCGCCCTGGT GCTCTGCGCC GCCCTGGCGG TCGTCCGCGC AGCAAATCCT 
TGCTGTTCCC ACCCATGTCA AAACCAAGGT ATTTGTATGA GCACAGGATT TGACCAGTAT 
AAGTGTGACT GTACCCGAAC AGGATTCTAC GGCGAAAACT GCTCAACACC GGAATTTCTG 
ACAAGAATAA AATTATACCT GAAACCCACT CCAAATACAG TACACTACAT ACTTACCCAC 
TTCAAGGGAG TCTGGAACAT TGTCAATAAC ATCCCCTTCC TGCGAAATAC AATTATGAAA 
TATGTGTTGA CATCCCGGTC ACATTTGATT GAGAGTCCAC CAACTTATAA TGTGAACTAC 
GGCTATAAAA GCTGGGAAGC CTTTTCTAAC CTCTCCTATT ATACCAGAGC TCTTCCCCCT 
GTACCTGATG ACTGTCCAAC ACCCATGGGT GTGAAAGGCA AGAAAGAGCT TCCTGATTCA 
AAAGAGATTG TGGAAAAGTT TCTTCTGCGA AGAAAGTTCA TTCCTGATCC CCAAGGCACC 
AATATGATGT TTGCATTCTT TGCCCAGCAC TTTACCCATC AATTTTTCAA GACAGATCAT 
AAGCGAGGAC CAGCTTTCAC CAAAGGATTG GGCCATGGGG TGGACTTAAA TCATGTTTAT 
GGGGAAACTT TGGATAGACA ACATAAACTG CGCCTTTTCA AGGATGGAAA AATGAAATAT 
CAGGTAATTG ATGGAGAGGT GTATCCTCCT ACCGTCAAAG ATACTCAGGT CGAGATGATC 
TACCCACCTC ATGTTCCTGA ACACCTGCAG TTTGCTGTGG GCCAGGAGGT CTTTGGTCTG 
GTGCCTGGTC TGATGATGTA TGCCACCATT TGGCTGCGGG AGCATAACAG AGTGTGTGAT 
GTGCTTAAAC AGGAGCACCC AGAATGGGAT GATGAGCGGT TATTCCAGAC GAGCAGGCTA 
ATACTGATAG GAGAAACCAT TAAGATTGTG ATTGAAGACT ATGTACAACA CTTGAGTGGC 
TATCACTTCA AGCTGAAGTT TGACCCAGAG CTGCTTTTCA ACCAACAATT CCAGTACCAA 
AACCGCATTG CTGCTGAGTT TAACACACTC TACCACTGGC ATCCCCTCCT GCCTGACACC 
TTGCAAATAG ATGACCAGGA GTACAATTTC CAACAGTTTA TCTACAACAA CTCTATATTA 
TTGGAACATG GCCTTACCCA GTTTGTGGAA TCATTCAGCA GGCAAATTGC TGGCAGGGTT 
GCCGGTGGCA GGAATGTTCC AGCTGCAGTA CAACAAGTAG CAAAAGCTTC GATTGACCAG 
AGCAGACAGA TGAAATACCA GTCTCTTAAT GAGTATCGCA AACGCTTTAG GCTGAAGCCC 
TATACATCAT TCGAAGAACT TACAGGAGAG AAGGAAATGG CTGCGGGGTT GGAGGCCCTT 
TATGGTGATA TTGATGCCAT GGAGCTGTAT CCTGCCCTCT TGGTAGAAAA GCCTCGTCCA 
GATGCCATCT TTGGTGAGAC CATGGTAGAA ATGGGAGCAC CATTCTCCTT GAAAGGACTT 
ATGGGTAATC CCATCTGTTC ACCTGACTAC TGGAAGCCTA GCACCTTTGG TGGAGAAGTA 
GGCTTTAAAA TCATCAACAC TGCCTCAATC CAGTCTCTCA TCTGCAATAA CGTGAAGGGC 
TGTCCATTCA CTGCATTCTC TGTTCAAGAC GGACAACTCA CCAAAACAGT CACCATTAAT 
GCAAGCTCTT CGCACTCCGG TCTAGATGAC ATCAATCCCA CAGTCCTACT GAAAGAACGG 
TCAACTGAAC TATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PTGS2 ( XM_005622228.2 ) cDNA ORF clone, Canis lupus familiaris(dog) -> XP_005622285.1 Canis lupus familiaris prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (PTGS2), transcript variant X2, mRNA.

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CloneID	OCe08927
Clone ID Related Accession (Same CDS sequence)	XM_005622228.2
Accession Version	XM_005622228.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1719bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-09-16
Organism	Canis lupus familiaris(Dog)
Product	prostaglandin G/H synthase 2 isoform X2
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003726067.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 17, 2015 this sequence version replaced XM_005622228.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGCACAG GATTTGACCA GTATAAGTGT GACTGTACCC GAACAGGATT CTACGGCGAA 
AACTGCTCAA CACCGGAATT TCTGACAAGA ATAAAATTAT ACCTGAAACC CACTCCAAAT 
ACAGTACACT ACATACTTAC CCACTTCAAG GGAGTCTGGA ACATTGTCAA TAACATCCCC 
TTCCTGCGAA ATACAATTAT GAAATATGTG TTGACATCCC GGTCACATTT GATTGAGAGT 
CCACCAACTT ATAATGTGAA CTACGGCTAT AAAAGCTGGG AAGCCTTTTC TAACCTCTCC 
TATTATACCA GAGCTCTTCC CCCTGTACCT GATGACTGTC CAACACCCAT GGGTGTGAAA 
GGCAAGAAAG AGCTTCCTGA TTCAAAAGAG ATTGTGGAAA AGTTTCTTCT GCGAAGAAAG 
TTCATTCCTG ATCCCCAAGG CACCAATATG ATGTTTGCAT TCTTTGCCCA GCACTTTACC 
CATCAATTTT TCAAGACAGA TCATAAGCGA GGACCAGCTT TCACCAAAGG ATTGGGCCAT 
GGGGTGGACT TAAATCATGT TTATGGGGAA ACTTTGGATA GACAACATAA ACTGCGCCTT 
TTCAAGGATG GAAAAATGAA ATATCAGGTA ATTGATGGAG AGGTGTATCC TCCTACCGTC 
AAAGATACTC AGGTCGAGAT GATCTACCCA CCTCATGTTC CTGAACACCT GCAGTTTGCT 
GTGGGCCAGG AGGTCTTTGG TCTGGTGCCT GGTCTGATGA TGTATGCCAC CATTTGGCTG 
CGGGAGCATA ACAGAGTGTG TGATGTGCTT AAACAGGAGC ACCCAGAATG GGATGATGAG 
CGGTTATTCC AGACGAGCAG GCTAATACTG ATAGGAGAAA CCATTAAGAT TGTGATTGAA 
GACTATGTAC AACACTTGAG TGGCTATCAC TTCAAGCTGA AGTTTGACCC AGAGCTGCTT 
TTCAACCAAC AATTCCAGTA CCAAAACCGC ATTGCTGCTG AGTTTAACAC ACTCTACCAC 
TGGCATCCCC TCCTGCCTGA CACCTTGCAA ATAGATGACC AGGAGTACAA TTTCCAACAG 
TTTATCTACA ACAACTCTAT ATTATTGGAA CATGGCCTTA CCCAGTTTGT GGAATCATTC 
AGCAGGCAAA TTGCTGGCAG GGTTGCCGGT GGCAGGAATG TTCCAGCTGC AGTACAACAA 
GTAGCAAAAG CTTCGATTGA CCAGAGCAGA CAGATGAAAT ACCAGTCTCT TAATGAGTAT 
CGCAAACGCT TTAGGCTGAA GCCCTATACA TCATTCGAAG AACTTACAGG AGAGAAGGAA 
ATGGCTGCGG GGTTGGAGGC CCTTTATGGT GATATTGATG CCATGGAGCT GTATCCTGCC 
CTCTTGGTAG AAAAGCCTCG TCCAGATGCC ATCTTTGGTG AGACCATGGT AGAAATGGGA 
GCACCATTCT CCTTGAAAGG ACTTATGGGT AATCCCATCT GTTCACCTGA CTACTGGAAG 
CCTAGCACCT TTGGTGGAGA AGTAGGCTTT AAAATCATCA ACACTGCCTC AATCCAGTCT 
CTCATCTGCA ATAACGTGAA GGGCTGTCCA TTCACTGCAT TCTCTGTTCA AGACGGACAA 
CTCACCAAAA CAGTCACCAT TAATGCAAGC TCTTCGCACT CCGGTCTAGA TGACATCAAT 
CCCACAGTCC TACTGAAAGA ACGGTCAACT GAACTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005622285.1
CDS	120..1838
Translation	MSTGFDQYKCDCTRTGFYGENCSTPEFLTRIKLYLKPTPNTVHYILTHFKGVWNIVNNIPFLRNTIMKYVLTSRSHLIESPPTYNVNYGYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGKKELPDSKEIVEKFLLRRKFIPDPQGTNMMFAFFAQHFTHQFFKTDHKRGPAFTKGLGHGVDLNHVYGETLDRQHKLRLFKDGKMKYQVIDGEVYPPTVKDTQVEMIYPPHVPEHLQFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWDDERLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDTLQIDDQEYNFQQFIYNNSILLEHGLTQFVESFSRQIAGRVAGGRNVPAAVQQVAKASIDQSRQMKYQSLNEYRKRFRLKPYTSFEELTGEKEMAAGLEALYGDIDAMELYPALLVEKPRPDAIFGETMVEMGAPFSLKGLMGNPICSPDYWKPSTFGGEVGFKIINTASIQSLICNNVKGCPFTAFSVQDGQLTKTVTINASSSHSGLDDINPTVLLKERSTEL

Target ORF information:

RefSeq Version	XM_005622228.2
Organism	Canis lupus familiaris(Dog)
Definition	Canis lupus familiaris prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (PTGS2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005622228.2

ORF Insert Sequence:

ATGAGCACAG GATTTGACCA GTATAAGTGT GACTGTACCC GAACAGGATT CTACGGCGAA 
AACTGCTCAA CACCGGAATT TCTGACAAGA ATAAAATTAT ACCTGAAACC CACTCCAAAT 
ACAGTACACT ACATACTTAC CCACTTCAAG GGAGTCTGGA ACATTGTCAA TAACATCCCC 
TTCCTGCGAA ATACAATTAT GAAATATGTG TTGACATCCC GGTCACATTT GATTGAGAGT 
CCACCAACTT ATAATGTGAA CTACGGCTAT AAAAGCTGGG AAGCCTTTTC TAACCTCTCC 
TATTATACCA GAGCTCTTCC CCCTGTACCT GATGACTGTC CAACACCCAT GGGTGTGAAA 
GGCAAGAAAG AGCTTCCTGA TTCAAAAGAG ATTGTGGAAA AGTTTCTTCT GCGAAGAAAG 
TTCATTCCTG ATCCCCAAGG CACCAATATG ATGTTTGCAT TCTTTGCCCA GCACTTTACC 
CATCAATTTT TCAAGACAGA TCATAAGCGA GGACCAGCTT TCACCAAAGG ATTGGGCCAT 
GGGGTGGACT TAAATCATGT TTATGGGGAA ACTTTGGATA GACAACATAA ACTGCGCCTT 
TTCAAGGATG GAAAAATGAA ATATCAGGTA ATTGATGGAG AGGTGTATCC TCCTACCGTC 
AAAGATACTC AGGTCGAGAT GATCTACCCA CCTCATGTTC CTGAACACCT GCAGTTTGCT 
GTGGGCCAGG AGGTCTTTGG TCTGGTGCCT GGTCTGATGA TGTATGCCAC CATTTGGCTG 
CGGGAGCATA ACAGAGTGTG TGATGTGCTT AAACAGGAGC ACCCAGAATG GGATGATGAG 
CGGTTATTCC AGACGAGCAG GCTAATACTG ATAGGAGAAA CCATTAAGAT TGTGATTGAA 
GACTATGTAC AACACTTGAG TGGCTATCAC TTCAAGCTGA AGTTTGACCC AGAGCTGCTT 
TTCAACCAAC AATTCCAGTA CCAAAACCGC ATTGCTGCTG AGTTTAACAC ACTCTACCAC 
TGGCATCCCC TCCTGCCTGA CACCTTGCAA ATAGATGACC AGGAGTACAA TTTCCAACAG 
TTTATCTACA ACAACTCTAT ATTATTGGAA CATGGCCTTA CCCAGTTTGT GGAATCATTC 
AGCAGGCAAA TTGCTGGCAG GGTTGCCGGT GGCAGGAATG TTCCAGCTGC AGTACAACAA 
GTAGCAAAAG CTTCGATTGA CCAGAGCAGA CAGATGAAAT ACCAGTCTCT TAATGAGTAT 
CGCAAACGCT TTAGGCTGAA GCCCTATACA TCATTCGAAG AACTTACAGG AGAGAAGGAA 
ATGGCTGCGG GGTTGGAGGC CCTTTATGGT GATATTGATG CCATGGAGCT GTATCCTGCC 
CTCTTGGTAG AAAAGCCTCG TCCAGATGCC ATCTTTGGTG AGACCATGGT AGAAATGGGA 
GCACCATTCT CCTTGAAAGG ACTTATGGGT AATCCCATCT GTTCACCTGA CTACTGGAAG 
CCTAGCACCT TTGGTGGAGA AGTAGGCTTT AAAATCATCA ACACTGCCTC AATCCAGTCT 
CTCATCTGCA ATAACGTGAA GGGCTGTCCA TTCACTGCAT TCTCTGTTCA AGACGGACAA 
CTCACCAAAA CAGTCACCAT TAATGCAAGC TCTTCGCACT CCGGTCTAGA TGACATCAAT 
CCCACAGTCC TACTGAAAGA ACGGTCAACT GAACTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Expression of iNOS, COX-2 and VEGF in canine mammary tumours and non-neoplastic mammary glands: Association with clinicopathological features and tumour grade.
Acta veterinaria Hungarica65(3)382-393(2017 09)
Anadol E,Yar Saglam AS,Gultiken N,Karakas K,Alcigir E,Alkan H,Kanca H

Low expression of cyclooxygenase-2 in chronic kidney disease in young dogs.
Research in veterinary science10971-73(2016 Dec)
Yabuki A,Miyazaki A,Ichii O,Kohyama M,Sawa M,Yamato O

Activation of MEK/ERK pathways through NF-?B activation is involved in interleukin-1?-induced cyclooxygenease-2 expression in canine dermal fibroblasts.
Veterinary immunology and immunopathology168(3-4)223-32(2015 Dec)
Tsuchiya H,Nakano R,Konno T,Okabayashi K,Narita T,Sugiya H

Immunohistochemical expression of cyclooxygenase-2 in normal, hyperplastic and neoplastic canine lymphoid tissues.
Journal of comparative pathology151(1)35-41(2014 Jul)
Asproni P,Vignoli M,Cancedda S,Millanta F,Terragni R,Poli A

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PTGS2 cDNA ORF clone, Canis lupus familiaris(dog)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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