ATP1A1 cDNA ORF clone, Canis lupus familiaris(dog)

Gene
Clones
gRNAs

Summary

Gene Symbol	ATP1A1
Entrez Gene ID	403992
Full Name	ATPase Na+/K+ transporting subunit alpha 1
General protein information	Preferred Names ATPase Na+/K+ transporting subunit alpha 1 Names sodium/potassium-transporting ATPase subunit alpha-1 ATPase, Na+/K+ transporting, alpha 1 polypeptide Na(+)/K(+) ATPase alpha-1 subunit sodium pump subunit alpha-1
Gene Type	protein-coding
Organism	Canis lupus familiaris(dog)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001003306.2	NP_001003306.1	sodium/potassium-transporting ATPase subunit alpha-1 precursor

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Atp1a1	NP_659149.1
Danio rerio (zebrafish)	atp1a1a.4	NP_571764.1
	ATP1A1	XP_001112674.1
Bos taurus (cattle)	ATP1A1	NP_001070266.1
Gallus gallus (chicken)	ATP1A1	NP_990852.1
Xenopus tropicalis (tropical clawed frog)	atp1a1	NP_989407.1
Homo sapiens (human)	ATP1A1	NP_000692.2
Pan troglodytes (chimpanzee)	ATP1A1	XP_513679.3
Danio rerio (zebrafish)	atp1a1b	NP_571765.1
Danio rerio (zebrafish)	atp1a1a.1	NP_571761.1
Canis lupus familiaris (dog)	ATP1A1	NP_001003306.1
Rattus norvegicus (Norway rat)	Atp1a1	NP_036636.1

Gene Ontology
Bibliography

Related articles in PubMed

Lack of Na(+),K (+)-ATPase expression in intercalated cells may be compensated by Na(+)-ATPase: a study on MDCK - C11 cells.
Sampaio MS, Bezerra IP, Pe?anha FL, Fonseca PH, Capella MA, Lopes AG
Cellular and molecular life sciences : CMLS65(19)3093-9(2008 Oct)

Novel role for Na,K-ATPase in phosphatidylinositol 3-kinase signaling and suppression of cell motility.
Barwe SP, Anilkumar G, Moon SY, Zheng Y, Whitelegge JP, Rajasekaran SA, Rajasekaran AK
Molecular biology of the cell16(3)1082-94(2005 Mar)

Na,K-ATPase response to osmotic stress in primary dog lens epithelial cells.
Old SE, Carper DA, Hohman TC
Investigative ophthalmology & visual science36(1)88-94(1995 Jan)

Mutation of a cysteine in the first transmembrane segment of Na,K-ATPase alpha subunit confers ouabain resistance.
Canessa CM, Horisberger JD, Louvard D, Rossier BC
The EMBO journal11(5)1681-7(1992 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data suggest that the presence of Na(+)-ATPase in intercalated cells may explain the adequate survival of cells that lack Na(+),K(+)-ATPase.
Title: Lack of Na(+),K (+)-ATPase expression in intercalated cells may be compensated by Na(+)-ATPase: a study on MDCK - C11 cells.

Na,K-ATPase has a role in phosphatidylinositol 3-kinase signaling and suppression of cell motility
Title: Novel role for Na,K-ATPase in phosphatidylinositol 3-kinase signaling and suppression of cell motility.

The following ATP1A1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ATP1A1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OCe34269	NM_001003306.2 Latest version!	Canis lupus familiaris ATPase Na+/K+ transporting subunit alpha 1 (ATP1A1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$629.30 $899.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ATP1A1 ( NM_001003306.2 ) cDNA ORF clone, Canis lupus familiaris(dog) -> NP_001003306.1 Canis lupus familiaris ATPase Na+/K+ transporting subunit alpha 1 (ATP1A1), mRNA.

Price & Availability↑

CloneID	OCe34269
Clone ID Related Accession (Same CDS sequence)	NM_001003306.2
Accession Version	NM_001003306.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3066bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Canis lupus familiaris(dog)
Product	sodium/potassium-transporting ATPase subunit alpha-1 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from L42173.1. On Aug 18, 2016 this sequence version replaced NM_001003306.1. ##Evidence-Data-START## Transcript exon combination :: L42173.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103936001, SAMEA103936002 [ECO:0000348] ##Evidence-Data-END##

ATGGGGAAGG GGGTCGGACG TGATAAATAT GAACCTGCGG CCGTTTCAGA GCATGGCGAC 
AAAAAAAAGG CCAAGAAAGA AAGGGATATG GATGAACTGA AGAAAGAAGT TTCTATGGAT 
GACCATAAAC TGAGCCTTGA TGAACTTCAT CGCAAATATG GAACAGACCT GAGTCGAGGC 
CTAACAACCG CTCGAGCTGC TGAGATCCTG GCTCGAGATG GTCCCAATGC CCTCACCCCA 
CCTCCCACCA CTCCCGAATG GGTCAAGTTC TGTCGGCAGC TGTTTGGAGG TTTCTCGATG 
TTACTGTGGA TTGGAGCGAT TCTTTGTTTC TTAGCTTATG GCATCCAAGC TGCCACGGAA 
GAGGAACCTC AAAATGATAA TCTATATCTT GGTGTGGTAC TATCAGCTGT TGTCATCATT 
ACTGGCTGTT TCTCCTACTA TCAAGAAGCT AAAAGTTCAA AGATCATGGA ATCCTTCAAA 
AACATGGTTC CTCAGCAAGC ACTTGTGATT CGAAATGGTG AAAAAATGAG CATCAACGCA 
GAGGAGGTTG TAATCGGGGA CTTGGTGGAA GTGAAAGGAG GAGACCGAAT CCCTGCTGAT 
CTCAGAATCA TATCTGCCAA CGGCTGCAAG GTGGATAACT CCTCGCTCAC TGGTGAATCA 
GAGCCCCAGA CTAGATCTCC AGACTTCACA AATGAAAACC CCCTGGAAAC GAGGAATATT 
GCCTTCTTCT CAACCAACTG CGTGAAAGGT ACTGCGCGCG GCATTGTTGT ATACACTGGG 
GATCGCACTG TCATGGGAAG AATTGCCACA CTTGCTTCTG GGCTGGAAGG AGGCCAGACT 
CCCATCGCTG CAGAAATTGA ACATTTTATC CATATCATCA CGGGTGTGGC CGTGTTTCTG 
GGCGTGTCCT TCTTTATCCT TTCTTTGATC CTTGAGTATA CCTGGCTTGA GGCCGTCATC 
TTTCTCATCG GAATCATCGT AGCCAATGTG CCAGAAGGTC TGCTGGCCAC TGTCACGGTA 
TGTCTGACCC TCACTGCCAA ACGCATGGCA AGGAAAAACT GCTTAGTGAA GAACTTAGAA 
GCTGTGGAGA CCTTGGGATC CACGTCCACC ATCTGCTCAG ATAAAACTGG AACTCTGACT 
CAGAACCGGA TGACCGTTGC CCACATGTGG TTCGACAATC AAATCCACGA AGCCGACACG 
ACAGAGAATC AGAGTGGTGT CTCGTTCGAT AAGAGTTCAG CCACCTGGCT CGCTCTGTCC 
AGAATTGCGG GTCTTTGTAA CAGGGCGGTG TTTCAGGCTA ACCAGGAAAA CCTGCCTATC 
CTTAAGCGGG CAGTTGCAGG TGACGCCTCA GAGTCCGCAC TCTTAAAATG CATCGAGCTG 
TGCTGTGGTT CTGTGAAGGA GATGAGAGAT CGATATGCCA AGATTGTGGA GATCCCCTTC 
AACTCTACCA ACAAGTACCA GCTGTCCATC CACAAGAACC CTAACACGTC TGAACCCCGA 
CACCTGTTGG TGATGAAGGG TGCTCCGGAA AGGATCCTGG ACCGCTGCAG CTCCATCCTC 
CTGCACGGCA AGGAGCAGCC TCTGGATGAG GAGCTGAAGG ATGCCCTTCA GAATGCCTAC 
CTGGAGCTGG GCGGCCTCGG AGAGCGAGTG CTGGGTTTCC GCCACCTTTT CCTGCCAGAT 
GAACAGTTTC CTGAAGGGTT CCAGTTTGAC ACTGATGATG TGAATTTCCC TGTTGAGAAC 
CTCTGCTTTG TGGGCTTCAT CTCCATGATT GGCCCTCCAC GGGCTGCTGT TCCTGACGCT 
GTGGGCAAAT GCCGAGGTGC TGGAATTAAG GTCATTATGG TCACTGGAGA CCATCCGATC 
ACAGCCAAAG CCATTGCCAA AGGTGCAGGC ATCATCTCAG AAGGCAATGA GACCGTGGAA 
GACATTGCTG CCCGTCTCAA CATCCCAGTG AGGCAGGTGA ACCCCAGAGA CGCCAAGGCC 
TGTGTGGTAC ATGGAAGCGA CCTGAAAGAC ATGACCTCCG AGCAGCTGGA TGGCATTCTG 
AAGTACCACA CGGAGATCGT GTTTGCCAGG ACCTCTCCTC AGCAGAAGCT TATCATTGTG 
GAAGGCTGCC AGAGACAGGG GGCTATTGTG GCTGTAACTG GTGATGGCGT GAATGACTCT 
CCAGCCTTGA AGAAGGCAGA CATTGGGGTT GCCATGGGGA TTGTTGGCTC CGACGCGTCT 
AAGCAAGCTG CCGACATGAT TCTTCTAGAT GACAACTTTG CGTCAATTGT GACTGGAGTA 
GAAGAAGGTC GTCTGATCTT TGATAACTTG AAGAAATCCA TTGCCTACAC CCTGACCAGT 
AACATTCCAG AGATCACCCC CTTCCTGATA TTTATTATTG CAAACATTCC ACTACCACTG 
GGGACTGTCA CCATCCTCTG CATTGACTTG GGCACAGACA TGGTCCCTGC TATCTCCCTG 
GCTTATGAGC AAGCTGAGAG CGACATCATG AAGAGACAGC CCAGAAACCC CAAAACGGAC 
AAGCTTGTGA ATGAGCGGCT GATCAGCATG GCCTATGGAC AGATCGGTAT GATCCAGGCC 
TTGGGGGGCT TCTTCACTTA CTTTGTGATT CTGGCTGAGA ACGGCTTCCT CCCGACCCAC 
CTGCTGGGCC TCCGAGTGGA CTGGGATGAC CGCTGGATCA ACGACGTGGA GGACAGCTAT 
GGGCAGCAGT GGACCTACGA ACAGAGGAAA ATCGTGGAGT TCACTTGCCA CACGGCCTTC 
TTCGTCAGTA TCGTGGTGGT GCAGTGGGCT GACTTGGTCA TCTGTAAGAC CAGGAGGAAC 
TCAGTCTTCC AGCAGGGGAT GAAGAACAAG ATCCTAATAT TTGGCCTCTT TGAAGAGACG 
GCCCTTGCTG CTTTCCTGTC CTACTGCCCT GGAATGGGTG TTGCCCTGAG GATGTACCCC 
CTCAAACCTA CCTGGTGGTT CTGTGCCTTT CCCTACTCTC TTCTCATCTT CGTGTACGAC 
GAAGTCCGAA AACTCATCAT CAGGCGACGC CCTGGCGGCT GGGTAGAGAA AGAAACCTAC 
TACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001003306.1
CDS	13..3078
Translation	MGKGVGRDKYEPAAVSEHGDKKKAKKERDMDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTTARAAEILARDGPNALTPPPTTPEWVKFCRQLFGGFSMLLWIGAILCFLAYGIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVIGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVKGTARGIVVYTGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKSSATWLALSRIAGLCNRAVFQANQENLPILKRAVAGDASESALLKCIELCCGSVKEMRDRYAKIVEIPFNSTNKYQLSIHKNPNTSEPRHLLVMKGAPERILDRCSSILLHGKEQPLDEELKDALQNAYLELGGLGERVLGFRHLFLPDEQFPEGFQFDTDDVNFPVENLCFVGFISMIGPPRAAVPDAVGKCRGAGIKVIMVTGDHPITAKAIAKGAGIISEGNETVEDIAARLNIPVRQVNPRDAKACVVHGSDLKDMTSEQLDGILKYHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIVGSDASKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPTHLLGLRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADLVICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCAFPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY

Target ORF information:

RefSeq Version	NM_001003306.2
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris ATPase Na+/K+ transporting subunit alpha 1 (ATP1A1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001003306.2

ORF Insert Sequence:

ATGGGGAAGG GGGTCGGACG TGATAAATAT GAACCTGCGG CCGTTTCAGA GCATGGCGAC 
AAAAAAAAGG CCAAGAAAGA AAGGGATATG GATGAACTGA AGAAAGAAGT TTCTATGGAT 
GACCATAAAC TGAGCCTTGA TGAACTTCAT CGCAAATATG GAACAGACCT GAGTCGAGGC 
CTAACAACCG CTCGAGCTGC TGAGATCCTG GCTCGAGATG GTCCCAATGC CCTCACCCCA 
CCTCCCACCA CTCCCGAATG GGTCAAGTTC TGTCGGCAGC TGTTTGGAGG TTTCTCGATG 
TTACTGTGGA TTGGAGCGAT TCTTTGTTTC TTAGCTTATG GCATCCAAGC TGCCACGGAA 
GAGGAACCTC AAAATGATAA TCTATATCTT GGTGTGGTAC TATCAGCTGT TGTCATCATT 
ACTGGCTGTT TCTCCTACTA TCAAGAAGCT AAAAGTTCAA AGATCATGGA ATCCTTCAAA 
AACATGGTTC CTCAGCAAGC ACTTGTGATT CGAAATGGTG AAAAAATGAG CATCAACGCA 
GAGGAGGTTG TAATCGGGGA CTTGGTGGAA GTGAAAGGAG GAGACCGAAT CCCTGCTGAT 
CTCAGAATCA TATCTGCCAA CGGCTGCAAG GTGGATAACT CCTCGCTCAC TGGTGAATCA 
GAGCCCCAGA CTAGATCTCC AGACTTCACA AATGAAAACC CCCTGGAAAC GAGGAATATT 
GCCTTCTTCT CAACCAACTG CGTGAAAGGT ACTGCGCGCG GCATTGTTGT ATACACTGGG 
GATCGCACTG TCATGGGAAG AATTGCCACA CTTGCTTCTG GGCTGGAAGG AGGCCAGACT 
CCCATCGCTG CAGAAATTGA ACATTTTATC CATATCATCA CGGGTGTGGC CGTGTTTCTG 
GGCGTGTCCT TCTTTATCCT TTCTTTGATC CTTGAGTATA CCTGGCTTGA GGCCGTCATC 
TTTCTCATCG GAATCATCGT AGCCAATGTG CCAGAAGGTC TGCTGGCCAC TGTCACGGTA 
TGTCTGACCC TCACTGCCAA ACGCATGGCA AGGAAAAACT GCTTAGTGAA GAACTTAGAA 
GCTGTGGAGA CCTTGGGATC CACGTCCACC ATCTGCTCAG ATAAAACTGG AACTCTGACT 
CAGAACCGGA TGACCGTTGC CCACATGTGG TTCGACAATC AAATCCACGA AGCCGACACG 
ACAGAGAATC AGAGTGGTGT CTCGTTCGAT AAGAGTTCAG CCACCTGGCT CGCTCTGTCC 
AGAATTGCGG GTCTTTGTAA CAGGGCGGTG TTTCAGGCTA ACCAGGAAAA CCTGCCTATC 
CTTAAGCGGG CAGTTGCAGG TGACGCCTCA GAGTCCGCAC TCTTAAAATG CATCGAGCTG 
TGCTGTGGTT CTGTGAAGGA GATGAGAGAT CGATATGCCA AGATTGTGGA GATCCCCTTC 
AACTCTACCA ACAAGTACCA GCTGTCCATC CACAAGAACC CTAACACGTC TGAACCCCGA 
CACCTGTTGG TGATGAAGGG TGCTCCGGAA AGGATCCTGG ACCGCTGCAG CTCCATCCTC 
CTGCACGGCA AGGAGCAGCC TCTGGATGAG GAGCTGAAGG ATGCCCTTCA GAATGCCTAC 
CTGGAGCTGG GCGGCCTCGG AGAGCGAGTG CTGGGTTTCC GCCACCTTTT CCTGCCAGAT 
GAACAGTTTC CTGAAGGGTT CCAGTTTGAC ACTGATGATG TGAATTTCCC TGTTGAGAAC 
CTCTGCTTTG TGGGCTTCAT CTCCATGATT GGCCCTCCAC GGGCTGCTGT TCCTGACGCT 
GTGGGCAAAT GCCGAGGTGC TGGAATTAAG GTCATTATGG TCACTGGAGA CCATCCGATC 
ACAGCCAAAG CCATTGCCAA AGGTGCAGGC ATCATCTCAG AAGGCAATGA GACCGTGGAA 
GACATTGCTG CCCGTCTCAA CATCCCAGTG AGGCAGGTGA ACCCCAGAGA CGCCAAGGCC 
TGTGTGGTAC ATGGAAGCGA CCTGAAAGAC ATGACCTCCG AGCAGCTGGA TGGCATTCTG 
AAGTACCACA CGGAGATCGT GTTTGCCAGG ACCTCTCCTC AGCAGAAGCT TATCATTGTG 
GAAGGCTGCC AGAGACAGGG GGCTATTGTG GCTGTAACTG GTGATGGCGT GAATGACTCT 
CCAGCCTTGA AGAAGGCAGA CATTGGGGTT GCCATGGGGA TTGTTGGCTC CGACGCGTCT 
AAGCAAGCTG CCGACATGAT TCTTCTAGAT GACAACTTTG CGTCAATTGT GACTGGAGTA 
GAAGAAGGTC GTCTGATCTT TGATAACTTG AAGAAATCCA TTGCCTACAC CCTGACCAGT 
AACATTCCAG AGATCACCCC CTTCCTGATA TTTATTATTG CAAACATTCC ACTACCACTG 
GGGACTGTCA CCATCCTCTG CATTGACTTG GGCACAGACA TGGTCCCTGC TATCTCCCTG 
GCTTATGAGC AAGCTGAGAG CGACATCATG AAGAGACAGC CCAGAAACCC CAAAACGGAC 
AAGCTTGTGA ATGAGCGGCT GATCAGCATG GCCTATGGAC AGATCGGTAT GATCCAGGCC 
TTGGGGGGCT TCTTCACTTA CTTTGTGATT CTGGCTGAGA ACGGCTTCCT CCCGACCCAC 
CTGCTGGGCC TCCGAGTGGA CTGGGATGAC CGCTGGATCA ACGACGTGGA GGACAGCTAT 
GGGCAGCAGT GGACCTACGA ACAGAGGAAA ATCGTGGAGT TCACTTGCCA CACGGCCTTC 
TTCGTCAGTA TCGTGGTGGT GCAGTGGGCT GACTTGGTCA TCTGTAAGAC CAGGAGGAAC 
TCAGTCTTCC AGCAGGGGAT GAAGAACAAG ATCCTAATAT TTGGCCTCTT TGAAGAGACG 
GCCCTTGCTG CTTTCCTGTC CTACTGCCCT GGAATGGGTG TTGCCCTGAG GATGTACCCC 
CTCAAACCTA CCTGGTGGTT CTGTGCCTTT CCCTACTCTC TTCTCATCTT CGTGTACGAC 
GAAGTCCGAA AACTCATCAT CAGGCGACGC CCTGGCGGCT GGGTAGAGAA AGAAACCTAC 
TACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Lack of Na(+),K (+)-ATPase expression in intercalated cells may be compensated by Na(+)-ATPase: a study on MDCK - C11 cells.
Cellular and molecular life sciences : CMLS65(19)3093-9(2008 Oct)
Sampaio MS,Bezerra IP,Pe?anha FL,Fonseca PH,Capella MA,Lopes AG

Novel role for Na,K-ATPase in phosphatidylinositol 3-kinase signaling and suppression of cell motility.
Molecular biology of the cell16(3)1082-94(2005 Mar)
Barwe SP,Anilkumar G,Moon SY,Zheng Y,Whitelegge JP,Rajasekaran SA,Rajasekaran AK

Na,K-ATPase response to osmotic stress in primary dog lens epithelial cells.
Investigative ophthalmology & visual science36(1)88-94(1995 Jan)
Old SE,Carper DA,Hohman TC

Mutation of a cysteine in the first transmembrane segment of Na,K-ATPase alpha subunit confers ouabain resistance.
The EMBO journal11(5)1681-7(1992 May)
Canessa CM,Horisberger JD,Louvard D,Rossier BC

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ATP1A1 cDNA ORF clone, Canis lupus familiaris(dog)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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