CAV1 cDNA ORF clone, Canis lupus familiaris(Dog)

Gene
Clones
gRNAs

Summary

Gene Symbol	CAV1
Entrez Gene ID	403980
Full Name	caveolin 1
General protein information	Preferred Names caveolin 1 Names caveolin-1 vesicular integral-membrane protein VIP21
Gene Type	protein-coding
Organism	Canis lupus familiaris(Dog)

mRNA and Protein(s)

mRNA	Protein	Name
XM_005628347.2	XP_005628404.1	caveolin-1 isoform X1
XM_005628347.3	XP_005628404.1	caveolin-1 isoform X1
XM_014118875.2	XP_013974350.1	caveolin-1 isoform X1
NM_001003296.1	NP_001003296.1	caveolin-1
XM_014118875.1	XP_013974350.1	caveolin-1 isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	CAV1	NP_001129290.1
Xenopus tropicalis (tropical clawed frog)	cav1	NP_001015750.1
Canis lupus familiaris (dog)	CAV1	NP_001003296.1
Bos taurus (cattle)	CAV1	NP_776429.1
Mus musculus (house mouse)	Cav1	NP_031642.1
	CAV1	NP_001162085.1
Rattus norvegicus (Norway rat)	Cav1	NP_113744.2
Homo sapiens (human)	CAV1	NP_001744.2
Gallus gallus (chicken)	CAV1	NP_001099134.1
Danio rerio (zebrafish)	cav1	NP_997816.1

Gene Ontology
Bibliography

Related articles in PubMed

EPLIN is a crucial regulator for extrusion of RasV12-transformed cells.
Ohoka A, Kajita M, Ikenouchi J, Yako Y, Kitamoto S, Kon S, Ikegawa M, Shimada T, Ishikawa S, Fujita Y
Journal of cell science128(4)781-9(2015 Feb)

Expression of caveolin-1 in the early phase of beta-TCP implanted in dog mandible.
Chou CT, Bhawal UK, Watanabe N, Kuboyama N, Chang WJ, Lee SY, Abiko Y
Journal of biomedical materials research. Part B, Applied biomaterials101(5)804-12(2013 Jul)

Gene expression profiling of early intervertebral disc degeneration reveals a down-regulation of canonical Wnt signaling and caveolin-1 expression: implications for development of regenerative strategies.
Smolders LA, Meij BP, Onis D, Riemers FM, Bergknut N, Wubbolts R, Grinwis GC, Houweling M, Groot Koerkamp MJ, van Leenen D, Holstege FC, Hazewinkel HA, Creemers LB, Penning LC, Tryfonidou MA
Arthritis research & therapy15(1)R23(2013 Jan)

Immunohistochemical and molecular analysis of caveolin-1 expression in canine mammary tumors.
Zuccari DA, Castro R, Gavioli AF, Mancini UM, Frade CS, Leonel C
Genetics and molecular research : GMR11(1)153-65(2012 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

results demonstrate that knockdown of EPLIN or Cav-1 substantially suppresses apical extrusion of transformed cells, implying that the expression of these molecules is required for the elimination of newly emerging transformed cells from the epithelium.
Title: EPLIN is a crucial regulator for extrusion of RasV12-transformed cells.

To better understand the role of caveolin-1 in bone homeostasis and response to beta-TCP scaffold, beta-TCP was implanted into mandible defects, and gene expression profiles were examined focused on the molecular components involved in caveolin-1 regulation.
Title: Expression of caveolin-1 in the early phase of beta-TCP implanted in dog mandible.

Early intervertebral disc degeneration involves down-regulation of Caveolin-1 expression
Title: Gene expression profiling of early intervertebral disc degeneration reveals a down-regulation of canonical Wnt signaling and caveolin-1 expression: implications for development of regenerative strategies.

Malignant mammary cells showed a loss of Cav-1 expression. Our findings indicate that Cav-1 is a potential prognostic marker for canine mammary tumors.
Title: Immunohistochemical and molecular analysis of caveolin-1 expression in canine mammary tumors.

Alcohol promotes the myocardial oxidative stress and fibrosis through an elevated expression of PYK2 and a lowered expression of caveolin-1.
Title: [Roles of PYK2 and caveolin-1 in alcoholic cardiomyopathy and the effect of drug intervention].

The following CAV1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CAV1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OCe34268	NM_001003296.1 Latest version!	Canis lupus familiaris caveolin 1 (CAV1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OCe16496	XM_005628347.3 Latest version!	Canis lupus familiaris caveolin 1 (CAV1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OCe16496	XM_014118875.2 Latest version!	Canis lupus familiaris caveolin 1 (CAV1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
View Old Accession Versions >>
OCe16496	XM_005628347.2	Canis lupus familiaris caveolin 1, caveolae protein, 22kDa (CAV1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OCe16496	XM_014118875.1	Canis lupus familiaris caveolin 1, caveolae protein, 22kDa (CAV1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CAV1 ( NM_001003296.1 ) cDNA ORF clone, Canis lupus familiaris(Dog) -> NP_001003296.1 Canis lupus familiaris caveolin 1 (CAV1), mRNA.

Price & Availability↑

CloneID	OCe34268
Clone ID Related Accession (Same CDS sequence)	NM_001003296.1
Accession Version	NM_001003296.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 537bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-27
Organism	Canis lupus familiaris(dog)
Product	caveolin-1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U47060.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U47060.1, DN368106.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103936001, SAMEA103936002 [ECO:0000348] ##Evidence-Data-END##

ATGTCTGGGG GCAAATACGT AGACTCCGAG GGGCACCTCT ACACCGTTCC CATCCGGGAG 
CAGGGCAACA TCTACAAGCC CAACAACAAG GCCATGGCGG AGGAGATGAG CGAGAAGCAG 
GTGTACGACG CGCACACCAA GGAAATCGAC CTGGTCAACC GCGACCCCAA GCATCTCAAC 
GACGACGTGG TCAAGATTGA TTTTGAAGAT GTGATTGCAG AACCAGAAGG AACACACAGT 
TTTGATGGCA TCTGGAAGGC CAGCTTCACC ACCTTCACTG TGACAAAATA CTGGTTTTAC 
CGCTTGCTGT CTGCCCTCTT TGGCATCCCA ATGGCACTCA TATGGGGCAT TTACTTTGCC 
ATTCTTTCTT TCCTGCACAT CTGGGCAGTT GTGCCGTGCA TTAAGAGTTT CCTGATTGAG 
ATTCAGTGCA TCAGCCGTGT CTATTCCATC TACGTCCACA CCTTCTGTGA CCCGTTCTTT 
GAGGCTGTTG GCAAAATATT CAGCAATATC CGCATCAACA TGCAGAAAGA AACATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001003296.1
CDS	1..537
Translation	MSGGKYVDSEGHLYTVPIREQGNIYKPNNKAMAEEMSEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTFCDPFFEAVGKIFSNIRINMQKET

Target ORF information:

RefSeq Version	NM_001003296.1
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris caveolin 1 (CAV1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001003296.1

ORF Insert Sequence:

ATGTCTGGGG GCAAATACGT AGACTCCGAG GGGCACCTCT ACACCGTTCC CATCCGGGAG 
CAGGGCAACA TCTACAAGCC CAACAACAAG GCCATGGCGG AGGAGATGAG CGAGAAGCAG 
GTGTACGACG CGCACACCAA GGAAATCGAC CTGGTCAACC GCGACCCCAA GCATCTCAAC 
GACGACGTGG TCAAGATTGA TTTTGAAGAT GTGATTGCAG AACCAGAAGG AACACACAGT 
TTTGATGGCA TCTGGAAGGC CAGCTTCACC ACCTTCACTG TGACAAAATA CTGGTTTTAC 
CGCTTGCTGT CTGCCCTCTT TGGCATCCCA ATGGCACTCA TATGGGGCAT TTACTTTGCC 
ATTCTTTCTT TCCTGCACAT CTGGGCAGTT GTGCCGTGCA TTAAGAGTTT CCTGATTGAG 
ATTCAGTGCA TCAGCCGTGT CTATTCCATC TACGTCCACA CCTTCTGTGA CCCGTTCTTT 
GAGGCTGTTG GCAAAATATT CAGCAATATC CGCATCAACA TGCAGAAAGA AACATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CAV1 ( XM_005628347.2 ) cDNA ORF clone, Canis lupus familiaris(Dog) -> XP_005628404.1 Canis lupus familiaris caveolin 1, caveolae protein, 22kDa (CAV1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OCe16496
Clone ID Related Accession (Same CDS sequence)	XM_005628347.2 , XM_005628347.3 , XM_014118875.2 , XM_014118875.1
Accession Version	XM_005628347.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 444bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-09-16
Organism	Canis lupus familiaris(Dog)
Product	caveolin-1 isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003726084.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 17, 2015 this sequence version replaced XM_005628347.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGAGG AGATGAGCGA GAAGCAGGTG TACGACGCGC ACACCAAGGA AATCGACCTG 
GTCAACCGCG ACCCCAAGCA TCTCAACGAC GACGTGGTCA AGATTGATTT TGAAGATGTG 
ATTGCAGAAC CAGAAGGAAC ACACAGTTTT GATGGCATCT GGAAGGCCAG CTTCACCACC 
TTCACTGTGA CAAAATACTG GTTTTACCGC TTGCTGTCTG CCCTCTTTGG CATCCCAATG 
GCACTCATAT GGGGCATTTA CTTTGCCATT CTTTCTTTCC TGCACATCTG GGCAGTTGTG 
CCGTGCATTA AGAGTTTCCT GATTGAGATT CAGTGCATCA GCCGTGTCTA TTCCATCTAC 
GTCCACACCT TCTGTGACCC GTTCTTTGAG GCTGTTGGCA AAATATTCAG CAATATCCGC 
ATCAACATGC AGAAAGAAAC ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005628404.1
CDS	172..615
Translation	MAEEMSEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTFCDPFFEAVGKIFSNIRINMQKET

Target ORF information:

RefSeq Version	XM_005628347.2
Organism	Canis lupus familiaris(Dog)
Definition	Canis lupus familiaris caveolin 1, caveolae protein, 22kDa (CAV1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005628347.2

ORF Insert Sequence:

ATGGCGGAGG AGATGAGCGA GAAGCAGGTG TACGACGCGC ACACCAAGGA AATCGACCTG 
GTCAACCGCG ACCCCAAGCA TCTCAACGAC GACGTGGTCA AGATTGATTT TGAAGATGTG 
ATTGCAGAAC CAGAAGGAAC ACACAGTTTT GATGGCATCT GGAAGGCCAG CTTCACCACC 
TTCACTGTGA CAAAATACTG GTTTTACCGC TTGCTGTCTG CCCTCTTTGG CATCCCAATG 
GCACTCATAT GGGGCATTTA CTTTGCCATT CTTTCTTTCC TGCACATCTG GGCAGTTGTG 
CCGTGCATTA AGAGTTTCCT GATTGAGATT CAGTGCATCA GCCGTGTCTA TTCCATCTAC 
GTCCACACCT TCTGTGACCC GTTCTTTGAG GCTGTTGGCA AAATATTCAG CAATATCCGC 
ATCAACATGC AGAAAGAAAC ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CAV1 ( XM_005628347.3 ) cDNA ORF clone, Canis lupus familiaris(Dog) -> XP_005628404.1 Canis lupus familiaris caveolin 1 (CAV1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OCe16496
Clone ID Related Accession (Same CDS sequence)	XM_005628347.2 , XM_005628347.3 , XM_014118875.2 , XM_014118875.1
Accession Version	XM_005628347.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 444bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-04
Organism	Canis lupus familiaris(dog)
Product	caveolin-1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006596.3) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 5, 2017 this sequence version replaced XM_005628347.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGAGG AGATGAGCGA GAAGCAGGTG TACGACGCGC ACACCAAGGA AATCGACCTG 
GTCAACCGCG ACCCCAAGCA TCTCAACGAC GACGTGGTCA AGATTGATTT TGAAGATGTG 
ATTGCAGAAC CAGAAGGAAC ACACAGTTTT GATGGCATCT GGAAGGCCAG CTTCACCACC 
TTCACTGTGA CAAAATACTG GTTTTACCGC TTGCTGTCTG CCCTCTTTGG CATCCCAATG 
GCACTCATAT GGGGCATTTA CTTTGCCATT CTTTCTTTCC TGCACATCTG GGCAGTTGTG 
CCGTGCATTA AGAGTTTCCT GATTGAGATT CAGTGCATCA GCCGTGTCTA TTCCATCTAC 
GTCCACACCT TCTGTGACCC GTTCTTTGAG GCTGTTGGCA AAATATTCAG CAATATCCGC 
ATCAACATGC AGAAAGAAAC ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005628404.1
CDS	168..611
Translation	MAEEMSEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTFCDPFFEAVGKIFSNIRINMQKET

Target ORF information:

RefSeq Version	XM_005628347.3
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris caveolin 1 (CAV1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005628347.3

ORF Insert Sequence:

ATGGCGGAGG AGATGAGCGA GAAGCAGGTG TACGACGCGC ACACCAAGGA AATCGACCTG 
GTCAACCGCG ACCCCAAGCA TCTCAACGAC GACGTGGTCA AGATTGATTT TGAAGATGTG 
ATTGCAGAAC CAGAAGGAAC ACACAGTTTT GATGGCATCT GGAAGGCCAG CTTCACCACC 
TTCACTGTGA CAAAATACTG GTTTTACCGC TTGCTGTCTG CCCTCTTTGG CATCCCAATG 
GCACTCATAT GGGGCATTTA CTTTGCCATT CTTTCTTTCC TGCACATCTG GGCAGTTGTG 
CCGTGCATTA AGAGTTTCCT GATTGAGATT CAGTGCATCA GCCGTGTCTA TTCCATCTAC 
GTCCACACCT TCTGTGACCC GTTCTTTGAG GCTGTTGGCA AAATATTCAG CAATATCCGC 
ATCAACATGC AGAAAGAAAC ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CAV1 ( XM_014118875.2 ) cDNA ORF clone, Canis lupus familiaris(Dog) -> XP_013974350.1 Canis lupus familiaris caveolin 1 (CAV1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OCe16496
Clone ID Related Accession (Same CDS sequence)	XM_005628347.2 , XM_005628347.3 , XM_014118875.2 , XM_014118875.1
Accession Version	XM_014118875.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 444bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-04
Organism	Canis lupus familiaris(dog)
Product	caveolin-1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006596.3) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 5, 2017 this sequence version replaced XM_014118875.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGAGG AGATGAGCGA GAAGCAGGTG TACGACGCGC ACACCAAGGA AATCGACCTG 
GTCAACCGCG ACCCCAAGCA TCTCAACGAC GACGTGGTCA AGATTGATTT TGAAGATGTG 
ATTGCAGAAC CAGAAGGAAC ACACAGTTTT GATGGCATCT GGAAGGCCAG CTTCACCACC 
TTCACTGTGA CAAAATACTG GTTTTACCGC TTGCTGTCTG CCCTCTTTGG CATCCCAATG 
GCACTCATAT GGGGCATTTA CTTTGCCATT CTTTCTTTCC TGCACATCTG GGCAGTTGTG 
CCGTGCATTA AGAGTTTCCT GATTGAGATT CAGTGCATCA GCCGTGTCTA TTCCATCTAC 
GTCCACACCT TCTGTGACCC GTTCTTTGAG GCTGTTGGCA AAATATTCAG CAATATCCGC 
ATCAACATGC AGAAAGAAAC ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_013974350.1
CDS	214..657
Translation	MAEEMSEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTFCDPFFEAVGKIFSNIRINMQKET

Target ORF information:

RefSeq Version	XM_014118875.2
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris caveolin 1 (CAV1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_014118875.2

ORF Insert Sequence:

ATGGCGGAGG AGATGAGCGA GAAGCAGGTG TACGACGCGC ACACCAAGGA AATCGACCTG 
GTCAACCGCG ACCCCAAGCA TCTCAACGAC GACGTGGTCA AGATTGATTT TGAAGATGTG 
ATTGCAGAAC CAGAAGGAAC ACACAGTTTT GATGGCATCT GGAAGGCCAG CTTCACCACC 
TTCACTGTGA CAAAATACTG GTTTTACCGC TTGCTGTCTG CCCTCTTTGG CATCCCAATG 
GCACTCATAT GGGGCATTTA CTTTGCCATT CTTTCTTTCC TGCACATCTG GGCAGTTGTG 
CCGTGCATTA AGAGTTTCCT GATTGAGATT CAGTGCATCA GCCGTGTCTA TTCCATCTAC 
GTCCACACCT TCTGTGACCC GTTCTTTGAG GCTGTTGGCA AAATATTCAG CAATATCCGC 
ATCAACATGC AGAAAGAAAC ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CAV1 ( XM_014118875.1 ) cDNA ORF clone, Canis lupus familiaris(Dog) -> XP_013974350.1 Canis lupus familiaris caveolin 1, caveolae protein, 22kDa (CAV1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OCe16496
Clone ID Related Accession (Same CDS sequence)	XM_005628347.2 , XM_005628347.3 , XM_014118875.2 , XM_014118875.1
Accession Version	XM_014118875.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 444bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-09-16
Organism	Canis lupus familiaris(Dog)
Product	caveolin-1 isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003726084.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGAGG AGATGAGCGA GAAGCAGGTG TACGACGCGC ACACCAAGGA AATCGACCTG 
GTCAACCGCG ACCCCAAGCA TCTCAACGAC GACGTGGTCA AGATTGATTT TGAAGATGTG 
ATTGCAGAAC CAGAAGGAAC ACACAGTTTT GATGGCATCT GGAAGGCCAG CTTCACCACC 
TTCACTGTGA CAAAATACTG GTTTTACCGC TTGCTGTCTG CCCTCTTTGG CATCCCAATG 
GCACTCATAT GGGGCATTTA CTTTGCCATT CTTTCTTTCC TGCACATCTG GGCAGTTGTG 
CCGTGCATTA AGAGTTTCCT GATTGAGATT CAGTGCATCA GCCGTGTCTA TTCCATCTAC 
GTCCACACCT TCTGTGACCC GTTCTTTGAG GCTGTTGGCA AAATATTCAG CAATATCCGC 
ATCAACATGC AGAAAGAAAC ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_013974350.1
CDS	272..715
Translation	MAEEMSEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTFCDPFFEAVGKIFSNIRINMQKET

Target ORF information:

RefSeq Version	XM_014118875.1
Organism	Canis lupus familiaris(Dog)
Definition	Canis lupus familiaris caveolin 1, caveolae protein, 22kDa (CAV1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_014118875.1

ORF Insert Sequence:

ATGGCGGAGG AGATGAGCGA GAAGCAGGTG TACGACGCGC ACACCAAGGA AATCGACCTG 
GTCAACCGCG ACCCCAAGCA TCTCAACGAC GACGTGGTCA AGATTGATTT TGAAGATGTG 
ATTGCAGAAC CAGAAGGAAC ACACAGTTTT GATGGCATCT GGAAGGCCAG CTTCACCACC 
TTCACTGTGA CAAAATACTG GTTTTACCGC TTGCTGTCTG CCCTCTTTGG CATCCCAATG 
GCACTCATAT GGGGCATTTA CTTTGCCATT CTTTCTTTCC TGCACATCTG GGCAGTTGTG 
CCGTGCATTA AGAGTTTCCT GATTGAGATT CAGTGCATCA GCCGTGTCTA TTCCATCTAC 
GTCCACACCT TCTGTGACCC GTTCTTTGAG GCTGTTGGCA AAATATTCAG CAATATCCGC 
ATCAACATGC AGAAAGAAAC ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

EPLIN is a crucial regulator for extrusion of RasV12-transformed cells.
Journal of cell science128(4)781-9(2015 Feb)
Ohoka A,Kajita M,Ikenouchi J,Yako Y,Kitamoto S,Kon S,Ikegawa M,Shimada T,Ishikawa S,Fujita Y

Expression of caveolin-1 in the early phase of beta-TCP implanted in dog mandible.
Journal of biomedical materials research. Part B, Applied biomaterials101(5)804-12(2013 Jul)
Chou CT,Bhawal UK,Watanabe N,Kuboyama N,Chang WJ,Lee SY,Abiko Y

Gene expression profiling of early intervertebral disc degeneration reveals a down-regulation of canonical Wnt signaling and caveolin-1 expression: implications for development of regenerative strategies.
Arthritis research & therapy15(1)R23(2013 Jan)
Smolders LA,Meij BP,Onis D,Riemers FM,Bergknut N,Wubbolts R,Grinwis GC,Houweling M,Groot Koerkamp MJ,van Leenen D,Holstege FC,Hazewinkel HA,Creemers LB,Penning LC,Tryfonidou MA

Immunohistochemical and molecular analysis of caveolin-1 expression in canine mammary tumors.
Genetics and molecular research : GMR11(1)153-65(2012 Jan)
Zuccari DA,Castro R,Gavioli AF,Mancini UM,Frade CS,Leonel C

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CAV1 cDNA ORF clone, Canis lupus familiaris(Dog)

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Target ORF information:

ORF Insert Sequence:

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